Effectiveness of high-intensity inspiratory muscle training, and resistance and aerobic exercise for cardiovascular health in chronic obstructive pulmonary disease (HIRAC-COPD): a... by Bin Yu, Wenbin Liu, Yuekong Hu, Yuling Huang, Qin Dai, Yuting Yang, Chunmei Fu, Zhen Zeng, Lingyan Li, Bo Yang, Zhiying Lei, Yunzhe Fan, Yuchen Li, Jiang Wu, Jinxiang Zhu, Peng Yu, Jiqi Yang, Haojiang Zuo, Peng Jia, Shujuan Yang

“…Methods This is a three-arm, parallel-group, assessor-blinded, randomized controlled trial with an eight-week intervention period and a 24-week follow-up. …”
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Determining the feasibility of a codesigned and personalised intervention (Veg4Me) to improve vegetable intake in young adults living in rural Australian communities: protocol for... by Ralph Maddison, John C Mathers, Sarah A McNaughton, Lauren C Blekkenhorst, Katherine M Livingstone, Gavin Abbott, Laura Alston, Jonathan C Rawstorn, Eric O, Yuxin Zhang, Scott Barnett, Stephanie R Partridge, Stephanie L Godrich, Gilly A Hendrie, Kate Dullaghan

“…Results will be disseminated to the scientific community through peer-reviewed publications and conference presentations.Trial registration number Australia New Zealand Clinical Trials Registry, ACTRN12623000179639p, prospectively registered on 21 February 2023, according to the World Health Organizational Trial Registration Data Set. …”
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A physical activity counseling intervention to promote health among pregnant women: a study protocol of randomized clinical trial by Xin Chen, Yong-fang Deng, Chun-feng Fu, Xiao Yang, Lingling Gao

“…Methods/design We will conduct a single-center, parallel, randomized controlled trial at a maternal–child health care center. …”
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Enhancing physical activity during pregnancy using a multi-theory model: a study protocol for a randomised controlled trial in China by Wei Zhang, Yu Shen, Le Zhang, Ying Jin, Ningning Liu, Suwen Feng, Xuesong Zhang

“…Participants will receive clarification regarding the study objectives, procedures and will be asked to sign informed consent in written form before the start of the study.Trial registration number ChiCTR2400080843. Prospectively registered on 8 February 2024.…”
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A multi-center trial-based economic evaluation of the SELF-program: A function-focused care program for nursing staff providing long-term care for geriatric clients in nursing home... by Ruben M W A Drost, Ghislaine A P G van Mastrigt, Stan Vluggen, Silke F Metzelthin, Michel H C Bleijlevens, Getty Huisman-de Waal, Janneke M de Man-van Ginkel, Sandra M G Zwakhalen

“…<h4>Methods</h4>The economic evaluation ran parallel to a two-arm multicenter cluster-randomized trial, in which the nursing staff in the intervention group received the SELF-program, and nursing staff in the control group received no program and delivered care as usual. …”
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Efficacy of linaclotide in combination with polyethylene glycol for bowel preparation in Chinese patients undergoing colonoscopy polypectomy: protocol for a randomised controlled t... by Jing Xu, Ping-ping Chen, Dong Chen, Hui-Ying Zhao, Xiao-Feng Cai, Xiao-Bin Wang, Chao-Xu Liu

“…This trial was registered on the Chinese Clinical Trial Registry with registration number ChiCTR2300075410…”
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Primary prevention of stroke: randomised controlled pilot trial protocol on engaging everyday activities promoting health by Aileen Bergström, Susanne Guidetti, Ann-Helen Patomella, Emelie Mälstam, Christina Eriksson, Elisabet Åkesson, Anders Kottorp, Eric Asaba

“…Study results will be disseminated through peer-review journals and presentations to mixed audiences at regional and international conferences.Trial registration number NCT03730701.…”
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Changes in Macular Pigment Optical Density and Serum Lutein Concentration in Japanese Subjects Taking Two Different Lutein Supplements. by Akira Obana, Masaki Tanito, Yuko Gohto, Shigetoshi Okazaki, Werner Gellermann, Paul S Bernstein

“…<h4>Methods</h4>Thirty-six healthy volunteers were recruited into this prospective, randomized, parallel-group, double-masked comparative study at a single institute. …”
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Automatic versus manual oxygen titration using a novel nasal high-flow device in medical inpatients with an acute illness: a randomised controlled trial by Mark Weatherall, Richard Beasley, Irene Braithwaite, Nethmi Kearns, Allie Eathorne, James Harper, Grace Bird, Nicholas Shortt

“…The aim of this study was to assess the efficacy of automatic oxygen titration using a closed-loop feedback system to achieve SpO2 within a prescribed target rangeMethods An open-label randomised parallel group trial was undertaken comparing automatic oxygen titration using a novel nasal high-flow device to manual oxygen titration using nasal high flow. …”
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Rationale, design and objectives of two phase III, randomised, placebo-controlled studies of GLPG1690, a novel autotaxin inhibitor, in idiopathic pulmonary fibrosis (ISABELA 1 and... by Kevin K Brown, Toby M Maher, Michael Kreuter, David J Lederer, Wim Wuyts, Nadia Verbruggen, Simone Stutvoet, Ann Fieuw, Paul Ford, Walid Abi-Saab, Marlies Wijsenbeek

“…Results will be reported in a peer-reviewed publication.Trial registration numbers NCT03711162; NCT03733444.…”
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Effects of poly-bioactive compounds on lipid profile and body weight in a moderately hypercholesterolemic population with low cardiovascular disease risk: a multicenter randomized... by Rosa Solà, Rosa-M Valls, José Puzo, José-Ramón Calabuig, Angel Brea, Anna Pedret, David Moriña, José Villar, Jesús Millán, Anna Anguera

“…AP is a product which could benefit patients having moderate hyperlipidemia and excess body weight.<h4>Trial registration</h4>ClinicalTrials.gov NCT01562080.…”
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Pitavastatin and Atorvastatin double-blind randomized comPArative study among hiGh-risk patients, including thOse with Type 2 diabetes mellitus, in Taiwan (PAPAGO-T Study). by Ping-Yen Liu, Liang-Yu Lin, Hung-Ju Lin, Chien-Hsun Hsia, Yi-Ren Hung, Hung-I Yeh, Tao-Cheng Wu, Ju-Yi Chen, Kuo-Liong Chien, Jaw-Wen Chen

“…To test the hypothesis that treatment with pitavastatin (2 mg/day) is not inferior to treatment with atorvastatin (10 mg/day) for reducing low-density lipoprotein cholesterol (LDL-C), a 12-week multicenter collaborative randomized parallel-group comparative study of high-risk ethnic Chinese patients with hypercholesterolemia was conducted in Taiwan. …”
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Efficacy of two doses of intra-articular ozone therapy for pain and functional mobility in knee osteoarthritis: a double-blind randomized trial by Zahra Arjmanddoust, Ahmad Nazari, Azar Moezy

“…Nevertheless, there was no significant difference in the efficacy between the two ozone concentrations. Trial registration The trial is registered on us ClinicalTrials.gov in 2024-05-01 with the following ID code NCT06088706.…”
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Focus group-supported development and psychometric exploration of an instrument to assess perceived physical exertion in nursing students by Eva Lorenz, Eva Grüne, Johanna Popp, Klaus Pfeifer, Johannes Carl

“…Methods We initially conducted two parallel semi-structured focus group interviews with purposefully sampled nursing students to gain insights into their daily physical load. …”
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Dynamic rasterstereography improves the detection of movement delays and dynamic asymmetries in the scapulothoracic kinematic of healthy subjects by Richard Julius Freytag, Jonas Wilhelm Moss, Filippo Maria Piana Jacquot, Jakob Zapatka, Rebecca Herrmann, Mahmoud Ragab, Sebastian Scheidt, Davide Cucchi

“…A metronome ensured consistent timing, and for DRS a grid of parallel light rays projected onto the back surface was captured using indirect optical measurement techniques. …”
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FACT: a randomised controlled trial to assess the feasibility of QbTest in the assessment process of attention deficit hyperactivity disorder (ADHD) for young people in prison—a fe... by Charlotte Lucy Hall, Prathiba Chitsabesan, Charlotte Lennox, Lesley-Anne Carter, Susan Young, Abdullah Kraam, Nikki Brown, Lloyd Wilkinson-Cunningham, Mindy Reeves

“…The objective of this study is to assess the feasibility and acceptability of QbTest in the assessment of ADHD within the CYPSE.Methods and analysis A single-centre parallel group feasibility randomised controlled trial will be conducted. …”
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Enhancing professional communication training in higher education through artificial intelligence(AI)-integrated exercises: study protocol for a randomised controlled trial by Gunther Meinlschmidt, Sara Koc, Emma Boerner, Marion Tegethoff, Thomas Simacek, Liam Schirmer, Michael Schneider

“…Classes will be assigned within a parallel group design to the AI condition (AI-enhanced exercises alongside teaching-as-usual, TAU, that includes classical exercises) or the control condition (TAU only). …”
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Effectiveness of specialist involvement in case discussion conferences with primary healthcare providers on the management of type 2 diabetes patients: a study protocol for a clust... by Jia Li, Jiawei Li, Chao Long, Aoqi Ge, Luping Hei, Zhikai Yang, Juanjuan Li, Xianjing Qin, Xinlu Song, Beibei Yuan

“…Methods This study will be a parallel cluster randomized controlled trial in which primary healthcare institutions in Shouguang city and Shangsi County will be randomly allocated to the intervention and control groups. …”
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Effect of PCSK9 inhibitor on early neurological deterioration in acute ischemic stroke patients with a history of coronary heart disease: a study protocol for a randomized controll... by Xing Gong, Xinting Yu, Lanlan Pu, Yang Jiao, Lin Liu, Hua Cao, Xiaofei Ji

“…Methods This is a prospective, randomized, parallel-group, blinded-endpoint, single-center clinical study. …”
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A digital programme to prevent falls and improve well-being in people living with dementia in the community: the KOKU-LITE feasibility randomised controlled trial protocol by Emma Stanmore, Jaheeda Gangannagaripalli, Emma Vardy

“…This trial aims to test the feasibility and acceptability of trial processes and usability of KOKU-LITE.Methods and analysis A two-arm, parallel, non-blinded feasibility randomised controlled trial will be conducted using mixed methods. …”
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