HELP-VDL: study protocol for a multicentre, open, randomised, controlled clinical trial comparing the use of the head-elevated laryngoscopy position and the use of a videolaryngosc... by Marc Fischler, Morgan Le Guen, Zoé Coppere, Guillaume Dufour, Jonathan Ouattara, Julie Trichereau

“…The results will be submitted for publication in peer-reviewed journals.Trial registration numberNCT03987009; Pre-results.…”
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Effects of whole grain, fish and bilberries on serum metabolic profile and lipid transfer protein activities: a randomized trial (Sysdimet). by Maria Lankinen, Marjukka Kolehmainen, Tiina Jääskeläinen, Jussi Paananen, Laura Joukamo, Antti J Kangas, Pasi Soininen, Kaisa Poutanen, Hannu Mykkänen, Helena Gylling, Matej Orešič, Matti Jauhiainen, Mika Ala-Korpela, Matti Uusitupa, Ursula Schwab

“…These changes may be related to known protective functions of HDL such as reverse cholesterol transport and could partly explain the known protective effects of fish consumption against atherosclerosis.<h4>Trial registration</h4>The study was registered at ClinicalTrials.gov NCT00573781.…”
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PHYSIO+++: protocol for a pilot randomised controlled trial assessing the feasibility of physiotherapist-led non-invasive ventilation for patients with hypoxaemia following abdomin... by Ianthe Boden, Linda Denehy, B Mark Smithers, Natasha Reid, Claire Hackett, Peter Kruger, Nina Ripley, Rachel M Walker, Louise Hope

“…Results will be published to inform future research.Trial registration number ACTRN12622000839707.…”
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Rehabilitation nursing for motor functional recovery of acute ischaemic stroke: study protocol for a randomised controlled trial by Yuanyuan Chen, Mei Li, Jianmiao Wang, Yuping Zhang, Jingfen Jin

“…Peer-reviewed journals and presentations at national and international conferences will be used to disseminate the results.Trial registration number NCT03702452.…”
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A randomized clinical trial to evaluate two doses of an intra-articular injection of LMWF-5A in adults with pain due to osteoarthritis of the knee. by David Bar-Or, Kristin M Salottolo, Holli Loose, Matthew J Phillips, Brian McGrath, Nathan Wei, James L Borders, John E Ervin, Alan Kivitz, Mark Hermann, Tammi Shlotzhauer, Melvin Churchill, Donald Slappey, Vaughan Clift

“…<h4>Methods</h4>This was a multicenter randomized, vehicle-controlled, double-blind, parallel study designed to evaluate the safety and efficacy of two doses of an intra-articular injection of LMWF-5A. …”
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Quadratus lumborum block is feasible alternative to epidural block for postoperative analgesia after open radical cystectomy: surgical and oncological outcomes of a randomised clin... by Erik Veskimäe, Andrus Korgvee, Heini Huhtala, Heikki Koskinen, Maija-Liisa Kalliomaki, Teuvo Tammela, Eija Junttila

“…The aim of this study was to assess the impact of bilateral single injection quadratum lumborum block (QLB) on patients’ recovery and complication rates compared with epidural analgesia after ORC in a single-centre, randomised, parallel-group trial including adult patients with bladder cancer. …”
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Positive-word stimuli via a smartphone application have no immediate-term effects on multi-directional reach ability in standing position: a randomized controlled trial by Kenta Azukizawa, Kodai Hirose, Yuta Morigami, Naoki Higashi, Hiroyuki Uchida, Kazuki Hirao

“…Objectives The purpose of the study was to examine the immediate-term effect of positive-word stimuli via a smartphone application on the multi-directional reach ability in standing position in young adults.Methods This study was an immediate-term, assessor-blinded, two-arm, parallel-group, randomized controlled trial among young adults recruited from one university in Japan. …”
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Protocol for a randomised controlled trial of the combined effects of the GLP-1 receptor agonist liraglutide and exercise on maintenance of weight loss and health after a very low-... by Mads Rosenkilde, Bente Merete Stallknecht, Simon Birk Kjær Jensen, Julie Rehné Lundgren, Charlotte Janus, Christian Rimer Juhl, Lisa Møller Olsen, Sten Madsbad, Signe Sørensen Torekov

“…Results will be submitted for publication in international peer-reviewed scientific journals.Trial registration number 2015-005585-32…”
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Study protocol. TRAAPREVIA—TRAnexamic acid for preventing blood loss following a cesarean delivery in women with a placenta pREVIA or low-lying placenta: a multicenter randomized,... by Loïc Sentilhes, Hugo Madar, Amélie Ifrah, Jean-Marie Chrétien, Catherine Deneux-Tharaux, the TRAAPREVIA Study Group, the Groupe de Recherche en Obstétrique et Gynécologie (GROG)

“…Methods and design This multicenter, double-blind, randomized controlled trial with two parallel groups will include 1380 women with placenta previa or a low-lying placenta and a cesarean delivery at a term ≥ 32 weeks, modeled on our previous study of tranexamic acid administered after cesarean deliveries (TRAAP2). …”
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Dose-dependent effect of coconut oil supplementation on obesity indices: a systematic review and dose-response meta-analysis of clinical trials by Zahra Gaeini, Zahra Bahadoran, Hanieh Malmir, Parvin Mirmiran

“…Systematic review registration PROSPERO CRD420251031291.…”
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Assessing the effectiveness and the feasibility of a group-based treatment for self-stigma in people with mental disorders in routine mental health services in North-East Italy: st... by Antonio Lasalvia, Luca Bodini, Doriana Cristofalo, Veronica Fin, Philip T. Yanos, Chiara Bonetto

“…Methods and analysis This pragmatic, multisite, superiority, randomized, wait-list controlled trial with two parallel arms will recruit over four hundred patients with severe mental disorders from 26 public community-based mental health centers in North-East Italy. …”
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Educational interventions delivered to prescribing advisers to influence primary care prescribing: a very low-cost pragmatic randomised trial using routine data from OpenPrescribin... by Helen J Curtis, Brian MacKenna, Bhavana Reddy, Alex J Walker, Sebastian Bacon, Rafael Perera, Ben Goldacre

“…Methods An opportunistic randomised, controlled parallel-group trial. Participants (clinical commissioning groups, CCGs) were randomised to intervention or control in a 1:1 ratio. …”
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Supervised pulmonary tele-rehabilitation and individualized home-based pulmonary rehabilitation for patients with COPD, unable to participate in center-based programs. The protocol... by Christina Nielsen, Nina Godtfredsen, Stig Molsted, Charlotte Ulrik, Thomas Kallemose, Henrik Hansen

“…The trial is registrered at ClinicalTrials.gov, identifier: NCT05664945 (23.12.2022).…”
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Effects of Music and Aromatherapy on Blood Pressure and Heart Rate Among Endodontic Patients: A Randomized Clinical Trial by Seyed Amir Mousavi, Fateme Nasiri, Melika Sadat Araghbidi Kashani, Ali Ghazalgoo, Pedram Iranmanesh, Soheil Shahbazi

“…Material and Methods In this single‐blind, parallel‐group, randomized clinical trial, 72 adult patients diagnosed with irreversible pulpitis and normal periapical conditions were referred to a dental school for endodontic treatment. …”
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Midline catheter (10 cm) versus long peripheral intravenous catheter (6.4 cm): Randomized clinical trial protocol with economic analysis. by Tiago Oliveira Teixeira, Leandro Augusto Hansel, Rodrigo do Nascimento Ceratti, Ivana Duarte Brum, Arlene Gonçalves Dos Santos Fernandes, Carolina Geske Saline, Marina Junges, Eneida Rejane Rabelo-Silva

“…The use of these devices remains incipient in Latin America, especially in Brazilian public institutions, requiring studies to evaluate evidence on the use and costs of these technologies in this specific population. Trial Registration: ClinicalTrials.gov. NCT05884294.…”
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Study protocol for a hybrid implementation-effectiveness trial of Game Changers for Cervical Cancer Prevention in Uganda. by Glenn J Wagner, Laura M Bogart, Joseph K B Matovu, Violet Gwokyalya, Jolly Beyeza-Kashesya, Allison Ober, Harold D Green, Sylvia Nakami, Margrethe Juncker, Eve Namisango, Emmanuel Luyirika, Ryan K McBain, Kathryn Bouskill, Rhoda K Wanyenze

“…In the Implementation phase, GC-CCP will be implemented over 36 months at each clinic, with screened women (index participants) enrolled as research participants receiving the intervention in the first 6 months as part of a parallel group RCT overseen by the research study team to evaluate efficacy for CC screening uptake among their enrolled social network members. …”
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High-velocity nasal insufflation in the management of overlap syndrome: a randomized clinical trial by Lamiaa Hassan Shaaban, Ashraf Zin EL-Abdeen Mohamed, Abanoub Hany Sadek, Waleed Gamal Elddin Khaleel

“…This study aims to investigate the effectiveness of HVNI in managing the overlap syndrome subgroup of patients presenting with hypercapnic respiratory failure. Methods This parallel randomized controlled study was performed on 46 overlap syndrome patients (combined COPD and OSA). …”
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An Examination into the Safety and Efficacy of Khapregesic&amp;reg;, a Khaya Senegalensis Preparation, on Women Experiencing Menstrual Pain and Menstrual Distress: A Randomized, Do... by Lopresti AL, Smith SJ, Ferdinands FR

“…Therefore, the purpose of this two-arm, parallel-group, randomized, double-blind, placebo-controlled trial was to examine the safety and efficacy of supplementation with a Khaya senegalensis preparation (Khapregesic®) on menstrual pain and menstrual distress in menstruating women.Methods: Eighty-four women experiencing menstrual pain and distress were supplemented 3g daily with this Khaya senegalensis preparation or a placebo for one menstrual cycle. …”
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Web-Based Application for Reducing Methamphetamine Use Among Aboriginal and Torres Strait Islander People: Randomized Waitlist Controlled Trial by Rachel Reilly, Rebecca McKetin, Federica Barzi, Tayla Degan, Nadine Ezard, Katherine Conigrave, Julia Butt, Yvette Roe, Handan Wand, Brendan Quinn, Wade Longbottom, Carla Treloar, Adrian Dunlop, James Ward

“…Future web-based apps for this population need to consider methods to increase participant engagement. Trial RegistrationAustralian New Zealand Clinical Trials Registry ACTRN12619000134123p; https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?…”
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Recruiting patients into a healthcare services trial: lessons learned from a feasibility study to investigate a patient-oriented navigation intervention for age-associated diseases by Kathrin Gödde, Hella Fügemann, Ulrike Grittner, Raphael Kohl, Andreas Meisel, Thomas Reinhold, Nina Rieckmann, Susanne Schnitzer, P. Markus Deckert, Nikolaj Frost, Christian H. Nolte, Stephan J. Schreiber, Ute Goerling, Christine Holmberg

“…Methods Detailed documentation of the recruitment process was conducted as part of the process evaluation for a mixed-methods feasibility study including randomized trials and parallel cohort studies to evaluate a patient-oriented navigation program. …”
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