Modified pulpotomy procedure in immature permanent teeth with apical periodontitis: a randomised controlled trial by Jun Wang, Wentao Shi, Wen Xiao, Zhengbing Chi

“…Clinical symptoms and complications were recorded, and parallel periapical radiographic images were used to measure changes in root length and apical diameter. …”
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Study protocol for a national observational cohort investigating frailty, delirium and multimorbidity in older surgical patients: the third Sprint National Anaesthesia Project (SNA... by Peter Martin, Akshay Shah, Jose Lourtie, Judith Partridge, Karen Williams, Tom Poulton, Iain Keith Moppett, Carol Green, Bob Evans, Claire Swarbrick, Laura Cortes, Christine Taylor

“…We will publish our findings in peer-reviewed journals and provide summary documents to our participants, sites, healthcare policy-makers and the public.Trial registration number ISRCTN67043129.…”
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A randomised controlled feasibility trial of a BabyWASH household playspace: The CAMPI study. by Sophie Budge, Paul Hutchings, Alison Parker, Sean Tyrrel, Sam Norton, Camila Garbutt, Fitsume Woldemedhin, Mohammed Yasin Jemal, Mathewos Moges, Siraj Hussen, Hunachew Beyene

“…This study was a two-armed, parallel-group, randomised, controlled feasibility trial of a HPS in rural Ethiopia. …”
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The UPBEAT nurse-delivered personalized care intervention for people with coronary heart disease who report current chest pain and depression: a randomised controlled pilot study. by Elizabeth A Barley, Paul Walters, Mark Haddad, Rachel Phillips, Evanthia Achilla, Paul McCrone, Harm Van Marwijk, Anthony Mann, Andre Tylee

“…PC allowed patients to work on unaddressed problems and appears cheaper than TAU.<h4>Trial registration</h4>Controlled-Trials.com ISRCTN21615909.…”
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Wool-derived keratin dressings versus usual care dressings for treatment of slow healing venous leg ulceration: a randomised controlled trial (Keratin4VLU) by Chris Bullen, Angela Wadham, Varsha Parag, Andrew Jull, Jill Waters, Carolina Weller

“…Objective To determine the effect of a keratin dressing for treating slow-to-heal venous leg ulcers (VLU) on VLU healing.Design Pragmatic parallel group randomised controlled trial.Setting Community-dwelling participants.Participants People aged 18 or more years with VLU (either present for more than 26 weeks or ulcer area larger than 5 cm2 or both).Intervention Wool-derived keratin dressing or usual care formulary of non-medicated dressings, on a background treatment with compression.Primary and secondary outcome measures Healing at 24 weeks based on blinded assessment of ulcer photographs. …”
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Effects of a drinking motives and readiness to change tailored digital alcohol intervention among online help-seekers: protocol for a randomised controlled trial by Jim McCambridge, Gillian Shorter, Marcus Bendtsen, Katarina Ulfsdotter Gunnarsson, Oskar Lundgren, Joel Crawford, Elizabeth Collier

“…This protocol describes a randomised controlled trial aimed at estimating the effectiveness of an intervention tailored to motives and readiness to change.Methods and analysis A three-arm, parallel groups, randomised controlled trial will be used to estimate the effects of a motives and readiness to change tailored intervention. …”
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Analysis Mortality in Patients with HIV-infection on Example of a Region with a High Prevalence of Infection by V. Ya. Rosenberg, Yu. K. Plotnikova, E. E. Voronin

“…The increase in mortality practically does not lead to an increase in mortality due to a parallel increase in the number of people living with HIV. 3. …”
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Decomposing the effect of normal aging and Alzheimer’s disease in brain morphological changes via learned aging templates by Jingru Fu, Daniel Ferreira, Örjan Smedby, Rodrigo Moreno

“…In the second step, we apply deep learning-based diffeomorphic registration to align the given image of a subject with a reference imaging template. …”
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Reflective mindfulness and emotional regulation training to enhance nursing students’ self-awareness, understanding, and regulation: a mixed method randomized controlled trial by Gihan Mohamed Mohamed Salem, Wilf Hashimi, Ayman Mohamed El-Ashry

“…Design and methods This study employed a convergent parallel mixed-method randomized controlled trial design. …”
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Theory-based mobile phone text messaging intervention for blood pressure control (TEXT4BP) among hypertensive patients in Nepal: study protocol for a feasibility randomised control... by Buna Bhandari, Padmanesan Narasimhan, Abhinav Vaidya, Rohan Jayasuriya

“…The findings of the study will be disseminated through peer-reviewed publications and conference presentations.Trial registration number ACTRN12619001213134.…”
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Randomised controlled trial to investigate the effectiveness of local oestrogen treatment in postmenopausal women undergoing pelvic organ prolapse surgery (LOTUS): a pilot study to... by Jane Daniels, Lee Middleton, Tina Sara Verghese, Versha Cheed, Lisa Leighton, Pallavi Manish Latthe

“…A larger trial is required to definitively address the role of perioperative oestrogen supplementation.Trial registration number ISRCTN46661996.…”
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Physical activity calorie equivalent (PACE) food labelling on discretionary foods in secondary school canteens in England: an efficacy cluster randomised controlled trial by Natalia Iris, Fehmidah Munir, Amanda J. Daley

“…The study aimed to assess the usefulness of implementing PACE labelling in school canteens and to conduct a process evaluation of using this type of food labelling with young people. Methods A parallel two-armed cluster RCT to evaluate a PACE labelling intervention in secondary schools (typically, adolescents aged 11 and above) in England was conducted. …”
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Evaluation of eight-style Tai chi on cognitive function in patients with cognitive impairment of cerebral small vessel disease: study protocol for a randomised controlled trial by Bin Chen, Hong-Jia Zhao, Hui Liang, Rui Xia, Xiaoyong Zhong, Xinghui Yan

“…The findings will be disseminated through peer-reviewed publications and at scientific conferences.Trial registration number ChiCTR2000033176; Pre-results.…”
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How Much Participant Outcome Data Is Missing from Sight: Findings from a Cohort of Trials Submitted to a German Research Ethics Committee. by Jamie J Kirkham, Kerry M Dwan, Anette Blümle, Erik von Elm, Paula R Williamson

“…The impact of funding source on missingness was also considered at the trial level. From 308 parallel group trials in the study cohort, 167 were published and 141 were unpublished. …”
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RESILSTIGMA. Resilience to self-stigmatization experienced by people living with HIV: Which self-reported factors improve awareness among health workers? by Christine Jacomet, Cécile Miele, Emilie Goncalves, Céline Lambert, Clément Belletier, Françoise Linard, Josiane Phalip-Le Besnerais, Pierre Dellamonica, Michaël Dambrun

“…<h4>Conclusions</h4>While the best means to combat self-stigmatization would be a social-ecological approach, it is fundamental to target in parallel individual vulnerability and protective factors accessible to health workers' interventions. …”
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Referral to Slimming World in UK Stop Smoking Services (SWISSS) versus stop smoking support alone on body weight in quitters: results of a randomised controlled trial by Paul Aveyard, Marcus Munafò, Amanda Lewis, Andrew Farmer, Deborah Lycett

“…Dietary modification may seem an obvious solution, but food restriction may increase cigarette craving and smoking relapse.Trial design An unblinded parallel randomised controlled trial.Methods Participants were adult smokers with a body mass index greater or equal to 23 kg/m2. …”
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Evaluating the feasibility of study methods for a future trial-based economic evaluation of a multistage shared decision-making program for type 2 diabetes mellitus: Protocol for a... by Anna Tichler, Dorijn F L Hertroijs, Ghislaine A P G van Mastrigt, Martijn C G J Brouwers, Dirk Ruwaard, Arianne M J Elissen

“…The results will guide the improvement of study procedures for the economic evaluation of our multistage shared decision-making program for type 2 diabetes.<h4>Trial registration</h4>The study is registered at ClinicalTrials.gov: NCT06410768.…”
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Pain medication tapering for patients with Persistent Spinal Pain Syndrome Type II, treated with Spinal Cord Stimulation: A RCT-study protocol of the PIANISSIMO study. by Maarten Moens, Cleo Lina Crunelle, Koen Putman, Elke Wuyts, Frenn Bultinck, Hubert Van Puyenbroeck, PIANISSIMO consortium, Lisa Goudman

“…<h4>Methods and design</h4>A three-arm, parallel-group multicenter randomized controlled trial will be conducted including 195 patients who will be randomized (1:1:1) to either (a) a standardized pain medication tapering program, (b) a personalized pain medication tapering program, or (c) no tapering program before SCS implantation, all with a follow-up period until 12 months after implantation. …”
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Arresting Early Childhood Caries with Silver Diamine Fluoride Gel Among Preschool Children: Protocol for a Randomised Clinical Trial by Anthony Yihong Cheng, Jieyi Chen, Faith Miaomiao Zheng, Duangporn Duangthip, Chun Hung Chu

“…<b>Methods</b>: This is a 30-month, randomised, active-controlled, parallel-group non-inferiority pragmatic clinical trial with two arms. …”
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Combating sarcopenia in geriatric rehabilitation patients: study protocol of the EMPOWER-GR observational cohort, sarcopenia awareness survey and randomised controlled feasibility... by Andrea B Maier, Carel GM Meskers, Laure MG Verstraeten, Janneke P van Wijngaarden, Marina Tol-Schilder

“…Results will be disseminated through publications in scientific peer-reviewed journals, conferences and social media.Trial registration number NL9444.…”
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