Improving the perception of respect for and the dignity of inpatients: a systematic review by Pablo Eduardo Pereira Dutra, Laiana Azevedo Quagliato, Antonio Egidio Nardi

“…The lack of interventional studies in this field has led to a gap in knowledge to be filled with better designed studies and effect measurements.PROSPERO registration number CRD42021241805.…”
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Study protocol: the SPInal NAVigation (SPINAV) trial – comparison of augmented reality surgical navigation, conventional image-guided navigation, and free-hand technique for pedicl... by Victor Gabriel El-Hajj, Anastasios Charalampidis, Daniel Fell, Erik Edström, Adrian Elmi-Terander, Paul Gerdhem

“…Patients and methods This is a single center, open label, parallel assignment, three arm, randomized, controlled trial, comparing: Augmented reality surgical navigation (ARSN), Infrared surgical navigation (IRSN) and Free-hand (FH) technique. …”
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A mix methodology study to compile the factors contributing towards poor uptake of antiretroviral therapy among high-risk groups: Female sex workers, people with intravenous drug u... by Debjani Sengupta, Archi Chandra, Upasana Poddar, Rahul Biswas, Pramit Ghosh, Arkaprovo Pal, Sandipta Chakraborty, Debjani Guchait

“…Conclusion: Monetary incentive for travel, single window service rapid service and process to access drugs from any center (via a central registration system if possible) may be useful.…”
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The influence of identity-oriented psychotrauma therapy on Hashimoto disease activity: a randomised controlled trial by Maria-Magdalena Macarenco, Cristian Opariuc-Dan, Teodora Georgescu

“…However, given the attrition-related sensitivity of some results, further replication in larger, well-retained samples is necessary before drawing definitive conclusions.Trial registration: ClinicalTrials.gov identifier: NCT04600349.…”
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Adverse events associated with endoscopic retrograde cholangiopancreatography: protocol for a systematic review and meta-analysis by Marcus Vaska, Yuhong Yuan, Nauzer Forbes, Grigorios I. Leontiadis, B. Joseph Elmunzer, Kirles Bishay, Zhao Wu Meng, Jordan Iannuzzi

“…A study team of eight data abstracters will independently determine study eligibility, assess quality and abstract data in parallel, with any two concordant entries constituting agreement and with discrepancies resolved by consensus. …”
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The effectiveness of community engagement using M-Mama champions in improving awareness of obstetric danger signs, birth preparedness and complication readiness among pregnant wome... by Alex Sanga, Stephen Kibusi, James Tumaini Kengia

“…It's, therefore worth an adoption for wider application.<h4>Trial registration</h4>NCT06325319 (Effect of Community Engagement Using M-Mama Champions), registered on 15th March 2024.…”
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Effectiveness of adapted self-help plus (SH+) to reduce psychological distress among university students in Indonesia (APRESIASI): protocol of a randomized controlled trial by Dhini Andriani, Fredrick D. Purba, Anke B. Witteveen, Neily Zakiyah, Marit Sijbrandij

“…If shown to be effective, SH + has the potential to be scaled up across university settings. Trial registration ISRCTN15761598, 14/07/2023.…”
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Can the accepting foreign clinical data policy improve innovation investment of pharmaceutical firms? Empirical evidence from China by Mengjuan Jiang, Jingjing Huang, Su Wang, Yulu Fan, Yuwen Chen, Yuwen Chen

“…IntroductionIn October 2017, China initiated adjustments to the registration procedures for imported drugs to promote accessibility to overseas drugs. …”
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Investigating the efficacy of transcranial direct current stimulation on chronic pain management in endometriosis patients: A randomized controlled trial protocol. by Tatiana Camila de Lima Alves da Silva, Hégila da Silva Dantas, Luiza Eduarda Macedo, Talita Duarte Martins, Edson Silva-Filho, Rodrigo Pegado, Linda McLean, Maria Thereza Albuquerque Barbosa Cabral Micussi

“…<h4>Methods</h4>This is a single-center, parallel, double-blinded, randomized, controlled clinical trial protocol study. …”
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Nebulised 3% hypertonic saline versus 0.9% saline for treating patients hospitalised with acute bronchiolitis: protocol for a randomised, double-blind, multicentre trial by Sara Szupieńko, Aleksandra Buczek, Henryk Szymański

“…The findings of the study will be submitted to a peer-reviewed journal, and abstracts will be submitted to relevant national and international conferences.Trial registration number ClinicalTrials.gov Registry (NCT06069336).…”
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Protocol of a tailored educational intervention for general practitioners on potentially inappropriate medications among older patients at community healthcare institutions in Beij... by Nan Li, Fang Wang, Xiaodong Guan, Mengyuan Fu, Luwen Shi, Haishaerjiang Wushouer, Xinyan Zhang, Xiaoyan Nie

“…The findings will be published in scientific and conference presentations.Trial registration number ChiCTR2100047788.…”
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Effects of integrated exercise approach on total testosterone levels in eumenorrheic women: a randomized controlled trial by Wajiha Shahid, Rabiya Noor

“…This was a two-armed parallel design, single-blinded, randomized controlled trial held from March 14, 2023, to February 21, 2024, in Aadil Hospital Defense Lahore. …”
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Supported Telemonitoring and Glycemic Control in People with Type 2 Diabetes: The Telescot Diabetes Pragmatic Multicenter Randomized Controlled Trial. by Sarah H Wild, Janet Hanley, Stephanie C Lewis, John A McKnight, Lucy B McCloughan, Paul L Padfield, Richard A Parker, Mary Paterson, Hilary Pinnock, Aziz Sheikh, Brian McKinstry

“…Current Controlled Trials, registration number ISRCTN71674628.<h4>Trial registration</h4>Current Controlled Trials ISRCTN 71674628.…”
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Assessment of prehospital tracheal intubation technique using initial direct laryngoscopy during videolaryngoscopy: randomized controlled simulated trial by Cédric Cibotto, Mathieu Pasquier, Nicolas Beysard, Frédéric Rouyer, Olivier Grosgurin, Laurent Bourgeois, Elio Erriquez, Ely Braun, Birgit Andrea Gartner, Thibaut Desmettre, Laurent Suppan

“…Conclusion In this simulated study among novice providers, direct airway visualization prior to videolaryngoscopy did not improve time to intubation or to ventilation. Trial registration ClinicalTrials.gov, Registration Number: NCT06918717, registered on April 8th, 2025. …”
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Effects of herbal medicines (Eunkyosan/Yin qiao san and Samsoeum/Shen su yin) for treating the common cold: A randomized, placebo-controlled, multicenter clinical trial by Kwan-Il Kim, Minna Hong, Yang-Chun Park, Beom-Joon Lee, Kitae Kim, Byoung Kab Kang, Jun-Yong Choi

“…Methods: A randomized, patient-assessor-blind, placebo-controlled, parallel, and multicenter clinical trial was conducted. …”
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Detour-Straddle 3D-like path planning of unmanned mining truck in open pit mines based on optimized ant colony algorithm by Mingyu GAO, Jiusheng BAO, Yan YIN, Deping HU, Kekun ZHANG, Chenzhong ZHU, Maosen WANG, Kai WANG

“…Firstly, a 3D map construction method based on laser point cloud is designed, and the valid point cloud data after filtering and registration are rasterized and the grid height is calculated, and the 3D map containing obstacle height information is obtained. …”
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Prolonged versus single dose in penicillin oral challenge testing: protocols for a pilot and definitive randomised controlled trial (PROSPECTOR studies) by Vito Sabato, Jason Trubiano, Sara Vogrin, Richard Sullivan, Michael Lane, Suran Fernando, Fiona James, Jonathan Grant Peter, Morgan Rose, Amy Legg, Irvin Ng, Ana Copaescu, Elise Mitri, Jack Godsell, Lene Heise Garvey, Philip Li

“…The aim of the PROSPECTOR studies was to determine the feasibility (PROSPECTOR-1) of a definitive trial (PROSPECTOR-2) to evaluate the safety and effectiveness of prolonged oral challenge (ie, 5 days) versus single-dose oral challenge in patients with a delayed or unknown penicillin allergy phenotype (PROSPECTOR-2).Methods and analysis A pair of double-blind two-arm parallel placebo-controlled trials will be undertaken—PROlonged versus Single dose in PEnicillin oral Challenge Testing double-blind parallel group randomised placebo-cOntrolled tRial (PROSPECTOR Studies). …”
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Statistical analysis plan for the Prenatal Iodine Supplementation and Early Childhood Neurodevelopment (PoppiE) randomised controlled trial by Thomas R. Sullivan, Tim J. Green, Jacqueline F. Gould, Maria M. Makrides, Karen P. Best

“…Methods PoppiE (Prenatal Iodine Supplementation and Early Childhood Neurodevelopment) is a multi-centre, parallel, two-arm, clinician, researcher and participant blinded randomised controlled trial. …”
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Percutaneous transhepatic or endoscopic ultrasound-guided biliary drainage in malignant distal bile duct obstruction using a self-expanding metal stent: Study protocol for a prospe... by Daniel Schmitz, Carlos T Valiente, Markus Dollhopf, Manuel Perez-Miranda, Armin Küllmer, Joan Gornals, Juan Vila, Jochen Weigt, Torsten Voigtländer, Eduardo Redondo-Cerezo, Thomas von Hahn, Jörg Albert, Stephan Vom Dahl, Torsten Beyna, Dirk Hartmann, Franziska Franck, Francisco Javier García-Alonso, Arthur Schmidt, Albert Garcia-Sumalla, Amaia Arrubla, Markus Joerdens, Tobias Kleemann, José Ramón Aparicio Tomo, Felix Grassmann, Jochen Rudi

“…<h4>Methods</h4>The study is designed as a non-randomized, controlled, parallel group, non-inferiority trial. Each of the 16 study centers performs the procedure with the best local expertise (PTBD or EUS-BD). …”
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Effectiveness of an institution-based adapted physical activity programme versus a home-based self-management programme for chronic poststroke adults: protocol for a randomised con... by Pascal Auquier, Etienne Satger, Nicolas Prieur-Blanc, Jean-Michel Viton, Laurent Bensoussan, Maëva Cotinat

“…The results will be disseminated via publications in the scientific literature, oral and poster presentations by partners at international scientific meetings and associations of patients.Trial registration NCT06061770.…”
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