ARTEMISIA: a mechanistic study of a novel Janus kinase 1 inhibitor to advance molecular understanding and precision medicine in asthma by Davinder Paul Singh Dosanjh, Erika Darrah, Tina Jellesmark Jensen, Zala Jevnikar, Alese Halvorson, Mathias Cardner, Rod Hughes, Sarah S. Grant, Adam Platt, Chris E. Brightling

“…Trial registration NCT06435273 (ClinicalTrials.gov). Registered 24th May 2024.…”
Get full text

Improving Quality of Care Through Detection of Complexity Among Community‐Dwelling Older People Receiving District‐Nurse Support: ImPaCt Study Randomised Controlled Trial by Jennifer Boak, Tshepo Rasekaba, Irene Blackberry

“…ABSTRACT Aim To examine the effect of implementing the patient complexity instrument (PCI) in addition to usual‐care on complexity detection, clinical‐care time allocation and referrals to supportive services compared to usual‐assessment alone. Design A parallel‐group‐blocked pragmatic randomised controlled trial. …”
Get full text

Mindfulness meditation and improvement in depressive symptoms among Spanish- and English speaking adults: A randomized, controlled, comparative efficacy trial. by Eric Lopez-Maya, Richard Olmstead, Michael R Irwin

“…<h4>Methods</h4>In this randomized clinical trial with 2 parallel treatment groups, adults with moderate levels of perceived stress (n = 76) were recruited from the Los Angeles community from October 2015 to March 2016, stratified into Spanish- (n = 36) and English speaking (n = 40) language groups, and randomized for 6 weeks of treatment with standardized mindful awareness practices (MAPs) or health education (HE). …”
Get full text

Effect of dose administration aids on adherence to self-administered medications: a systematic review protocol by Anthony Rodgers, Emily Atkins, Kanika Chaudhri, Richard O Day, Madeleine Kearney

“…The risk of bias will be ascertained by two reviewers in parallel using The Cochrane Risk of Bias Tool. A meta-analysis will be performed if data are homogenous.Ethics and dissemination Ethics approval will not be required for this study. …”
Get full text

Effects of Transcutaneous Electrical Acustimulation on Patients with Fibromyalgia Syndrome: Study Protocol of a Randomized, Double-Blind, Sham-Controlled Trial by Li Y, Fan B, Wang X, Hu N, Zhou X, Zhang Y, Mao P, Li Y

“…This study aims to evaluate the efficacy and mechanisms of TEA treatment for FMS.Design: This is a prospective, randomized, double-blind, and placebo-controlled trial with two parallel groups, conducted at a single center. Forty participants will be randomly assigned to either the TEA group or the sham-TEA group in a 1:1 ratio. …”
Get full text

Efficacy of therapeutic fasting and plant-based diet in patients with rheumatoid arthritis (NutriFast): study protocol for a randomised controlled clinical trial by Anika M Hartmann

“…Results of this trial will be disseminated through peer-reviewed publications and scientific presentations.Trial registration number NCT03856190.…”
Get full text

Chronic low back pain management: clinical and psychophysiological outcomes of multimodal approaches—a randomised controlled trial on yoga and mindfulness by Basit Ansari, Shamoon Noushad, Sadaf Ahmed, Yusra Saleem

“…Data will be collected at baseline (week 0), at the end of the intervention (week 12) and 12 weeks after the intervention (week 24). Trial registration number NCT06910982.…”
Get full text

Comparison of Vaginal Birth Rate between Induction of Labour and Expectant Management at 40 Weeks in Women with a Previous Caesarean Section: A Pilot Randomized Controlled Trial by K. Rajalakshmi, Gowri Dorairajan, Swetha S. Kumar, C. Palnivel

“…This trial is registered with CTRI/2018/09/015719 (date of registration 14th September 2018).…”
Get full text

Multicentre randomised phase II study of the perioperative administration of flurbiprofen axetil in patients with non-small cell lung cancer: study protocol of the FLAX Study by Kentaro Sakamaki, Katsuya Watanabe, Tetsukan Woo, Munetaka Masuda

“…Results will be published in a peer-reviewed journal.Trial registration number Japan Registry of Clinical Trials (jRCTs031190167; Pre-results) (https://jrct.niph.go.jp/).…”
Get full text

Intraoperative protective mechanical ventilation in patients requiring emergency abdominal surgery: the multicentre prospective randomised IMPROVE-2 study protocol by Samir Jaber, Emmanuel Futier, Karim Asehnoune, Bruno Pereira, Gerald Chanques, Justine Bourdier, Thomas Godet, Louisa Khaled, Lynda Araujo

“…Methods and analysis The IMPROVE-2 study is a multicentre randomised, parallel-group clinical trial of 680 patients requiring emergency abdominal surgery under general anaesthesia. …”
Get full text

Comparison of ultrasound-guided subtransverse process interligamentary plane block with paravertebral block for postoperative analgesia in thoracic surgery: protocol for a randomis... by Yang Liu, Hong Shi, Danyang Wang, Tianyi Zhu, Wenxin He

“…The findings will be submitted for publication in peer-reviewed journals.Trial registration number ChiCTR2200066909.…”
Get full text

Effects of upper-limb aerobic exercise plus general exercise versus general exercise alone among patients with spinal cord injury in northern Nigeria: A protocol for a randomized c... by Fatima Kachalla Gujba, Sonill Sooknunan Maharaj, Aminu Alhassan Ibrahim

“…<h4>Method</h4>This is a multicenter, assessor-blind, parallel group, randomized controlled superiority trial to be conducted among SCI patients attending three tertiary hospitals in Kano State, northern Nigeria. …”
Get full text

Analysis of photoluminescence decay kinetics of aluminum phthalocyanine nanoparticles interacting with immune cells by F. G. Bystrov, V. I. Makarov, D. V. Pominova, A. V. Ryabova, V. B. Loschenov

“…A model of surface molecules transitions from parallel to perpendicular position, regarding to the plane of the crystal nanoparticle was proposed.…”
Get full text

Near-infrared light devices versus landmark approach for peripheral venous access in the intensive care unit: protocol of a randomised controlled study by Mai-Anh Nay, Mathilde Wanneveich, Aude Ferrier, Amélie Despres, Aurélie Brasselet, Gaëtan Badre

“…The results will be submitted for publication in peer-reviewed journals.Trial registration number Clinicaltrials.gov: NCT06234293.…”
Get full text

MyKid’sNutrition mobile application: effect on mothers’ nutritional knowledge and nutritional status of preschool-aged children with undernutrition – a randomised controlled trial... by Ali Hojati, Mahdieh Abbasalizad Farhangi

“…Also, children’s weight and BMI for age z-scores changed more compared with the control group.Trial registration number IRCT20140907019082N11.…”
Get full text

Smartphone Application for Celiac Patients: Assessing Its Effect on Gastrointestinal Symptoms in a Randomized Controlled Clinical Trial by Zeinab Nikniaz, Zahra Akbari Namvar, Masood Shirmohammadi, Elham Maserat

“…Methods. In the present parallel randomized controlled clinical trial, 60 patients with CD were assigned randomly to receive education through a smartphone application (n=30) or conventional clinical education (n=30). …”
Get full text

Clinical advantages of cad-cam-fabricated full-arch fixed implant-supported monolithic zirconia dental prosthesis with digital modelling of the occlusion surfaces by R. A. Rozov, V. N. Trezubov, A. Pozzi

“…Prostheses were based on 237 implants Nobel Replace/Select/Groovy, Nobel Parallel CC. The number of supports for one prostheses was from 6 to 10, which averaged 7.64±1.08. …”
Get full text

Factor structure of the Utrecht Work Engagement Scale in a sample of Danish and Swedish haemodialysis nurses by Maria Lindberg, Kati Knudsen, Magnus Lindberg

“…Exploratory factor analysis based on polychoric correlations and parallel analysis identified one factor. Scaling assumptions were supported based on desirable levels of corrected item-total correlations. …”
Get full text

Annexin levels in GCF determine the imbalance of periodontal inflammatory regulation by Melis Yilmaz, İpek Bal, Sena Hanli, Emrah Turkmen, Nur Balci, Hilal Uslu Toygar

“…Conclusions: The data suggest that periodontitis is associated with a disruption of the balance between pro-inflammatory mechanisms (ANXA2 and IL-1beta) and inflammation resolution (ANXA1), in parallel with PISA levels. Clinical Trial Registration: ClinicalTrials.gov NCT06554756 (15/08/2024).…”
Get full text

Efficacy and safety of Cheonwangbosim-dan (Tian Wang Bu Xin Dan) for treatment of mild cognitive impairment: A randomized placebo-controlled pilot trial. by Jae-Hong Kim, Ae-Ran Kim, Bok-Nam Seo, Gwang-Cheon Park, Jeong-Soon Lee

“…This clinical trial adopted a double-blind, single-center, parallel-arm, prospective, randomized controlled pilot study design with a full analysis set. …”
Get full text