N-acetylcysteine in Kidney Disease: Molecular Mechanisms, Pharmacokinetics, and Clinical Effectiveness by Estefani Y. Hernández-Cruz, Omar E. Aparicio-Trejo, Fadi A. Hammami, Daniel Bar-Shalom, Martin Tepel, Jose Pedraza-Chaverri, Alexandra Scholze

“…Kidney function of the patient population and pathomechanisms of the kidney disease should guide rational NAC trial design. …”
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A case of severe ketoacidosis as the first clinical manifestation of type 2 diabetes mellitus in a youngster by Bruno Bombaci, Fortunato Lombardo, Stefano Passanisi, Sara Aramnejad, Rossella Morello, Mariella Valenzise, Giuseppina Salzano, Malgorzata Gabriela Wasniewska

“…The incidence of T2D in the pediatric population is increasing, paralleling the rise in obesity rates among youths. …”
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Dynamics of ideas about the concept of epileptic psychosis by Y. A. Yakovleva, M. Y. Kissin, Y. V. Popov, A. A. Pichikov, N. Y. Safonova, T. M. Goguadze

“…Introduction: psychosis in epilepsy is more common than in the general population. The frequency of psychotic mental disorders varies from 0,5% to 10%. …”
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Hygiene and prevention of the addictions in adolescents: existential-humanistic model by P. N. Moskvitin

“…After training statistically reliable difference of experimental group from control group in each of the parallels of the 8, 9 and 10 classes presented in research is revealed. …”
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The long-term impact of the COVID-19 pandemic on tuberculosis care and infection control measures in anti-retroviral therapy (ART) clinics in low- and middle-income countries: a mu... by Marcel Yotebieng, Lukas Fenner, Haruka Uemura, Jacqueline Huwa, Ellen Brazier, Marie Ballif, Oliver Ezechi, Anchalee Avihingsanon, Denna Michael, Jonathan Euvrard, Guy Muula, Nagalingeswaran Kumarasamy, Lameck Diero, Brian Otaalo, Eric Komena, Nicolas Banholzer, Lisa Perrig, Dominique Mahambu Nsonde, Sarah Obatsa, Patricia Lelo, Patrice Gouéssé, Idiovino Rafael, Richard Ramdé, I Ketut Agus Somia

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The dynamics of the gut microbiota in prediabetes during a four-year follow-up among European patients—an IMI-DIRECT prospective study by Liwei Lyu, Yong Fan, Josef Korbinian Vogt, Marc Clos-Garcia, Amelie Bonnefond, Helle Krogh Pedersen, Avirup Dutta, Robert Koivula, Sapna Sharma, Kristine Højgaard Allin, Caroline Brorsson, Henna Cederberg, Elizaveta Chabanova, Federico De Masi, Emmanouil Dermitzakis, Petra J. Elders, Marieke T. Blom, Monika Hollander, Rebeca Eriksen, Ian Forgie, Gary Frost, Giuseppe N. Giordano, Harald Grallert, Mark Haid, Tue Haldor Hansen, Bernd Jablonka, Tarja Kokkola, Anubha Mahajan, Andrea Mari, Timothy J. McDonald, Petra B. Musholt, Imre Pavo, Cornelia Prehn, Martin Ridderstråle, Hartmut Ruetten, Leen M.‘t Hart, Jochen M. Schwenk, Evelina Stankevic, Henrik S. Thomsen, Jagadish Vangipurapu, Henrik Vestergaard, Ana Viñuela, Mark Walker, Torben Hansen, Allan Linneberg, Henrik Bjørn Nielsen, Søren Brunak, Mark I. McCarthy, Philippe Froguel, Jerzy Adamski, Paul W. Franks, Marku Laakso, Joline W. J. Beulens, Ewan Pearson, Oluf Pedersen

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Rice residue management alternatives and nitrogen optimization: impact on wheat productivity, microbial dynamics, and enzymatic activities by Charul Chaudhary, Dharam B. Yadav, Virender S. Hooda, Ankur Chaudhary, Jagdish Parshad, Ankush Kumar, Rajbir SIngh Khedwal, Ashok Yadav

“…This increase in enzymatic activity was paralleled by a robust positive correlation between the microbial population and enzymatic activity across various residue retention practices. …”
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Machine learning identifies genes linked to neurological disorders induced by equine encephalitis viruses, traumatic brain injuries, and organophosphorus nerve agents by Liduo Yin, Morgen VanderGiessen, Morgen VanderGiessen, Vinoth Kumar, Benjamin Conacher, Po-Chien Haku Chao, Michelle Theus, Erik Johnson, Kylene Kehn-Hall, Kylene Kehn-Hall, Xiaowei Wu, Hehuang Xie

“…Valuable insights may be gleaned by drawing parallels to other extensively researched neuropathologies, such as traumatic brain injuries (TBI). …”
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Unlocking the dual healing powers of plant-based metallic nanoparticles: managing diabetes and tackling male infertility challenges by Ayesha Siddiqa, Rahmatullah Qureshi, Ghazala Yasmin, Shaista Rafique, Noor-Ul-Ain Zafar, Chudary Sadam Hussain, Sana ur Rehman, Neelum Naheed

“…DM impacts male reproductive health across four aspects: ejaculation, erectile dysfunction, structural alterations in reproductive organs, and alterations in semen quality. The population of male individuals with diabetes is steadily rising, paralleled by an increase in fertility issues among men. …”
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Metabolic signatures of adiposity in young adults: Mendelian randomization analysis and effects of weight change. by Peter Würtz, Qin Wang, Antti J Kangas, Rebecca C Richmond, Joni Skarp, Mika Tiainen, Tuulia Tynkkynen, Pasi Soininen, Aki S Havulinna, Marika Kaakinen, Jorma S Viikari, Markku J Savolainen, Mika Kähönen, Terho Lehtimäki, Satu Männistö, Stefan Blankenberg, Tanja Zeller, Jaana Laitinen, Anneli Pouta, Pekka Mäntyselkä, Mauno Vanhala, Paul Elliott, Kirsi H Pietiläinen, Samuli Ripatti, Veikko Salomaa, Olli T Raitakari, Marjo-Riitta Järvelin, George Davey Smith, Mika Ala-Korpela

“…Consistent with the causal influences of adiposity, weight changes were paralleled by extensive metabolic changes, suggesting a broadly modifiable systemic metabolite profile in early adulthood. …”
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Efficacy and Safety of Transcatheter Mitral Valve Edge-to-Edge Repair with a MitraClip Device in Real-World Canadian Practice by Shamir R. Mehta, MD, MSc, Anita Asgar, MD, Robert Boone, MD, Josep Rodes-Cabau, MD, PhD, Eric A. Cohen, MD, Andrew Czarnecki, MD, Marino Labinaz, MD, Shahar Lavi, MD, Nicolo Piazza, MD, Kevin R. Bainey, MD, Akshay Bagai, MD, Jean-Michel Paradis, MD, J.D. Schwalm, MD, Douglas Wright, MD, Helen Nguyen, BSc, Tara McCready, PhD, Rajibul Mian, PhD, John Webb, MD, Neil Fam, MD

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Topical TLR7 agonist and radiotherapy in patients with metastatic breast cancer by Ping Jin, Xiaochun Li, Francesco Marincola, Ena Wang, Sandra Demaria, Davide Bedognetti, Darawan Rinchai, Sylvia Adams, Yelena Novik, Ruth Oratz, David Stroncek, Judith Goldberg, Silvia Chiara Formenti, Maria Fenton-Kerimian, Pascale G Levine

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Long-term outcomes in leucine-rich glioma inactivated-1 autoimmune encephalitis and associated biomarkers of inflammation and neuronal and glial injury by Tyler L. Borko, Tyler L. Borko, Phillip Winters, Kelli M. Money, Stefan Sillau, Sadie Eggmann, Sean Selva, Alanna Ritchie, Ryan Kammeyer, Ryan Kammeyer, Gregory P. Owens, Jeffrey L. Bennett, Jeffrey L. Bennett, Amanda L. Piquet

“…The trend of clinical improvement is paralleled with a slow decline in NfL and GFAP levels, returning to levels like our control population after 6 and 3 years, respectively. …”
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Analyzing Waste Policy-Making from the Perspective of Local People in the Selected Villages of Kermanshah County by Parvin Rezaeibavandpour, Mohammad Akbarpour

“…Rural areas have likewise encountered various types of waste and their associated negative consequences, paralleling global trends. Consequently, effective waste management has emerged as a crucial response to these challenges. …”
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