Clinical and cost-effectiveness of a diabetes education and behavioural weight management programme versus a diabetes education programme in adults with a recent diagnosis of type... by Jennifer Bostock, Robbie Duschinsky, Stephen J Sharp, Stephen Morris, Simon J Griffin, Brett Doble, Alan Brennan, Amy L Ahern, Jenny Woolston, Emma Wells, Nazrul Islam, Emma Ruth Lawlor, Andrew J Hill, Ed Wilson, Carly A Hughes, Clare Boothby

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Leveraging genomic insights from the neglected malaria parasites P. malariae and P. ovale using selective whole genome amplification (SWGA) approach by Fathia Ben-Rached, Amit Kumar Subudhi, Chang Li, Mariah Alawi, Rohit Satyam, Sui Xu, Guoding Zhu, Raeece Naeem, Sara Mfarrej, Di Liu, Zenaida Stead, Caroline Askonas, Yaobao Liu, Jun Cao, Arnab Pain

“…On average, P. malariae had 93% of the genome covered by ≥ 10 reads; parallel improvements in genome coverage were achieved for both P. ovale spp. with 81% on average of the genome covered by ≥ 10 reads. …”
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Comprehensive Molecular Analysis of Disease-Related Genes as First-Tier Test for Early Diagnosis, Classification, and Management of Patients Affected by Nonsyndromic Ichthyosis by Tiziana Fioretti, Fabrizio Martora, Ilaria De Maggio, Adelaide Ambrosio, Carmelo Piscopo, Sabrina Vallone, Felice Amato, Diego Passaro, Fabio Acquaviva, Francesca Gaudiello, Daniela Di Girolamo, Valeria Maiolo, Federica Zarrilli, Speranza Esposito, Giuseppina Vitiello, Luigi Auricchio, Elena Sammarco, Daniele De Brasi, Roberta Petillo, Antonella Gambale, Fabio Cattaneo, Rosario Ammendola, Paola Nappa, Gabriella Esposito

“…In the attempt to molecularly classify 17 unrelated Italian patients referred with congenital nonsyndromic ichthyosis, we performed massively parallel sequencing of over 50 ichthyosis-related genes. …”
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Effectiveness of biomarker-guided duration of antibiotic treatment in children hospitalised with confirmed or suspected bacterial infection: the BATCH RCT by Cherry-Ann Waldron, Philip Pallmann, Simon Schoenbuchner, Debbie Harris, Lucy Brookes-Howell, Céu Mateus, Jolanta Bernatoniene, Katrina Cathie, Saul N Faust, Josie Henley, Lucy Hinds, Kerry Hood, Chao Huang, Sarah Jones, Sarah Kotecha, Sarah Milosevic, Helen Nabwera, Sanjay Patel, Stéphane Paulus, Colin VE Powell, Jenny Preston, Huasheng Xiang, Emma Thomas-Jones, Enitan D Carrol

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Severe menopausal symptoms and associated factors among post-menopausal women in Ambo town, West Shewa, Ethiopia: a cross-sectional study by Galana Takele Namara, Binyam Seifu Woldeyes, Dereje Yadesa Irenso, Daniel Belema Fekene, Gizachew Abdissa Bulto, Musa Abduro Fata, Warkitu Sileshi Ensermu, Amare Tesfaye Yami

“…Despite the fact that the population of menopausal women in Ethiopia is growing in parallel with their life expectancy, little is known about the severity and factors associated with menopausal symptoms among post-menopausal women. …”
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Focal Segmental Glomerulosclerosis Patient Baseline Characteristics in the Sparsentan Phase 3 DUPLEX Study by Howard Trachtman, Jai Radhakrishnan, Michelle N. Rheault, Charles E. Alpers, Jonathan Barratt, Hiddo J.L. Heerspink, Irene L. Noronha, Vlado Perkovic, Brad Rovin, Hernán Trimarchi, Muh Geot Wong, Alex Mercer, Jula Inrig, William Rote, Ed Murphy, Patricia W. Bedard, Sandra Roth, Stewart Bieler, Radko Komers

“…Results: The primary analysis population includes 371 patients (336 adult, 35 pediatric [<18 years]) who were randomized and received study drug (median age, 42 years). …”
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Effectiveness of socioecological model-guided, smart device-based, and self-management-oriented lifestyle (3SLIFE) intervention on healthy lifestyles and metabolic syndrome risk in... by Bin Yu, Yuchen Li, Chunlan Ma, Jan D. Reinhardt, Qingyu Dou, Haojiang Zuo, Xue Yang, Ming Li, Changwei Cai, Yunzhe Fan, Zixing Huang, Tong Pang, Qi Tang, Fen Yang, Tingting Ye, Peng Jia, Shujuan Yang

“…This study applies 3SLIFE to community-dwelling adults, aiming to improve healthy lifestyles. Methods In this parallel, cluster-randomized controlled trial, 20 communities in Southwestern China were randomly assigned 1:1 to either the intervention or control group. …”
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The Gorongosa elephants through war and recovery by Joyce Poole, Petter Granli

“…Près de 2200 avant la guerre, leur nombre a chuté en deçà de 200, affectant la structure de la population et les familles qui la composent, l’apparence physique des éléphants, leur constitution génétique et leur comportement (étude parallèle). …”
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Cost-effectiveness of Spironolactone for Adult Female Acne (SAFA): economic evaluation alongside a randomised controlled trial by Ingrid Muller, Miriam Santer, Beth Stuart, Paul Little, Matthew J Ridd, Karen Thomas, Nick Francis, Kim S Thomas, Gareth Griffiths, Natalia V Permyakova, Jacqui Nuttall, Irene Soulsby, Alison M Layton, Tracey H Sach, Sarah Pyne, Susanne Renz, Zina Eminton, Megan Lawrence

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Assessing spatial variability of soil macro fauna and tree canopy using fractal theory (Case study: Riparian Forest of Maroon River) by Shaieste Gholami, ehsan sayad, Hamid Taleshi

“…Soil macro fauna were sampled using 175 sampling point along parallel transects (perpendicular to the river). The distance between transects was 100m. …”
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A comparison of acceptability of contraceptive vaginal rings, pills, and injectables among cisgender women in Kenya and Zimbabwe: protocol for a mixed-methods study [version 1; pee... by Chelsea B. Polis, Irene V. Bruce, Francis O. Obare, Lisa B. Haddad, Cynthia Banda, Petros Isaakidis, Antwanette Heyns, Terrance Kufakunesu, Mercy Kamupira, Farai Machinga, Zachary A. Kwena, Aleck Mapangire, Regina F. Magore, Matheus Mathipa, Mercy Marimirofa, Mary Mudavanhu, Sanyukta Mathur, Prisca Mutero, Tatenda P. Mujuru, Collen Nyatsambo, Betty Njoroge, Leah Omondi, Sarah Okumu, Marlena G. Plagianos, Tevyne Omondi, Samuel Sithole, Greshon Rota, J. Brady Burnett-Zieman, Bruce Variano, George Odwe, Petina Musara, Serah Gitome, Gerald Hangaika, Kuziwa Kuwenyi, Elizabeth A. Bukusi

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A legume-enriched diet improves metabolic health in prediabetes mediated through gut microbiome: a randomized controlled trial by Xiaorong Wu, Alvin Surya Tjahyo, Vera Sergeyevna Brok Volchanskaya, Long Hui Wong, Xianning Lai, Yi Ning Yong, Farhana Osman, Shia Lyn Tay, Priya Govindharajulu, Shalini Ponnalagu, Rachel Tso, Hwee Sze Teo, Kaijie Khoo, Huan Fan, Chew Chan Goh, Clara Poh Lian Yap, Melvin Khee-Shing Leow, Christiani Jeyakumar Henry, Sumanto Haldar, Kevin Junliang Lim

“…The study was a 16-week, single-blind, parallel-design, randomized controlled trial (n = 63 intervention group (IG), n = 64 control group (CG); mean ± SD age 62.2 ± 6.3 years, BMI 23.8 ± 2.6 kg/m2). …”
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Needs assessment for a decision support tool in oral cancer requiring major resection and reconstruction: a mixed-methods study protocol by David Goldstein, John R de Almeida, Rosemary Martino, Douglas B Chepeha, David Forner, Paul Hong, Martin Corsten, Valeria E Rac, Andrew G Shuman, Anna M Sawka, Jonathan C Irish, Dale H Brown, S Mark Taylor, Patrick J Gullane, Jonathan R Trites, Ralph Gilbert, Matthew H Rigby, Jolie Ringash

“…It is a multi-institutional convergent parallel mixed-methods needs assessment study. Patients and surgeon dyads will be recruited to complete questionnaires related to their perception of the SDM process (nine-item Shared Decision-Making Questionnaire, SDM-Q-9 and SDM-Q-Doc) and to take part in semistructured interviews. …”
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Effects of Anti-CD20 Antibody Therapy on Immune Cell Dynamics in Relapsing-Remitting Multiple Sclerosis by Alice G. Willison, Ramona Hagler, Margit Weise, Saskia Elben, Niklas Huntemann, Lars Masanneck, Steffen Pfeuffer, Stefanie Lichtenberg, Kristin S. Golombeck, Lara-Maria Preuth, Leoni Rolfes, Menekse Öztürk, Tobias Ruck, Nico Melzer, Melanie Korsen, Stephen L. Hauser, Hans-Peter Hartung, Philipp A. Lang, Marc Pawlitzki, Saskia Räuber, Sven G. Meuth

“…Data were analyzed by conventional gating and unsupervised computational approaches. In parallel, different clinical parameters were longitudinally assessed. …”
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Posterior iliac crest vs. proximal tibia: distinct sources of anti-inflammatory and regenerative cells with comparable 6-month clinical outcomes in treatment of osteoarthritis by E. Mormone, L. Savastano, G. Rossi, F. Maruccia, G. Di Maggio, N. P. Sinisi, M. Sandri, M. Copetti, E. De Santis, V. Guerra, G. Biancofiore, C. Cisternino, E. Caradonna, P. Graziano, F. L. Gorgoglione

“…Methods A single-center, parallel, randomized controlled study was designed to investigate the efficacy of BMA from the posterior iliac crest compared to BMA from the proximal tibia, against a control group treated with PRP, in knee OA. …”
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Assessment of knowledge, attitudes, and performance of postgraduate nursing students regarding clinical reasoning and evidence-based nursing: a multicenter cross-sectional study in... by Zahra Mohebi, Azizallah Dehghan, Ali Taghinezhad, Sorur Javanmardifard, Mostafa Bijani

“…Additionally, it included three parallel components for evidence-based nursing: Evidence-Based Nursing Attitude (EBN-A), Evidence-Based Nursing Knowledge (EBN-K), and Evidence-Based Nursing Practice (EBN-P). …”
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Identification and Analysis of Effective Factors on the Trend of the Iranian Banking Network to Implement Green Banking by W. Qelich

“…In the following, the known factors are ranked and prioritized with Friedman's test. The statistical population of this research was all managers and banking experts in Tehran. …”
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CTN 328: immunogenicity outcomes in people living with HIV in Canada following vaccination for COVID-19 (HIV-COV): protocol for an observational cohort study by Cecilia T Costiniuk, Jean-Pierre Routy, Shari Margolese, Enrico Mandarino, Joel Singer, Mohammad-Ali Jenabian, Mario Ostrowski, Jonathan B Angel, Ann Burchell, Darrell Tan, Colin Kovacs, Mark Hull, Mark Brockman, Sharon Walmsley, Aslam H Anis, Marianne Harris, Curtis Cooper, Marc-André Langlois, Iva Kulic, Judy Needham, Zabrina Brumme

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Short-term exposure to PM2.5 constituents and mortality risks for diabetes subtypes and related complications in eastern China by Jingjing Zhang, Jiaying Fang, Jiajun Shen, Yalin Zhang, Yunquan Zhang, Hao Zheng

“…The highest odds ratio (OR) per IQR increase was 1.033 (95 % confidence interval: 1.018, 1.049) for NO3− (IQR: 10.8 μg/m3), followed by 1.030 (1.015, 1.045) for NH4+ (IQR: 6.4 μg/m3), 1.027 (1.014, 1.040) for OM (IQR: 7.5 μg/m3), 1.025 (1.012, 1.038) for BC (IQR: 1.3 μg/m3), and 1.020 (1.006, 1.034) for SO42− (IQR: 6.3 μg/m3). Parallel associations with various PM2.5 components were only observed for type 2 diabetes (T2D) instead of type 1 diabetes. …”
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The Eczema Bathing Study: Weekly versus daily bathing for people with eczema? Protocol of an online, randomised controlled trial [version 2; peer review: 1 approved, 2 approved wit... by Paul Leighton, Wei Chern Gavin Fong, Ingrid Muller, Laura Howells, Arabella Baker, Eleanor J Mitchell, Eleanor Harrison, Leila Thuma, Yimin Jiang, Lucy Bradshaw, Alan Montgomery, Fiona Cowdel, Matthew J Ridd, Jane Ravenscroft, Reiko J Tanaka, Miriam Santer, Richard Swinden, Nicholas Hilken, Carron Layfield, Richard Dooley, Sophia Collins, Clare Upton, Tracy Owen, Firoza Davies, Devin Patel, Mars Eddis-Finbow, Hywel C Williams, Goldie Putrym, Kim S Thomas, Amanda Roberts

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