Assessment of Bowel Preparation Using Low-Volume Sulphate-Based Preparations in Comparison with Macrogols: A Multicenter, Randomized, Comparative Clinical Study of the 3rd Phase by E. D. Fedorov, V. V. Veselov, S. V. Kashin, E. V. Tikhomirova, A. V. Veselov, D. V. Zavyalov, A. Kornowski, T. E. Gorskaya, M. Volteau, T. Ponchon

“…The proportion of patients with a successful bowel preparation (BBPS ≥6 scores) was high in both groups (OSS [PP-population]: 97.2 % (95 % confidence interval [CI] 89.5–99.3), Macrogol [PP-population]: 97.7 % (95 % CI: 90.7–99.4)). …”
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Recruiting patients into a healthcare services trial: lessons learned from a feasibility study to investigate a patient-oriented navigation intervention for age-associated diseases by Kathrin Gödde, Hella Fügemann, Ulrike Grittner, Raphael Kohl, Andreas Meisel, Thomas Reinhold, Nina Rieckmann, Susanne Schnitzer, P. Markus Deckert, Nikolaj Frost, Christian H. Nolte, Stephan J. Schreiber, Ute Goerling, Christine Holmberg

“…A key challenge of these studies, as for trials in general, is finding an effective recruitment strategy to reach the intended sample size in the targeted population. Methods Detailed documentation of the recruitment process was conducted as part of the process evaluation for a mixed-methods feasibility study including randomized trials and parallel cohort studies to evaluate a patient-oriented navigation program. …”
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Brachial plexus nerve block versus haematoma block for closed reduction of distal radius fracture in adults: The BLOCK Trial – a protocol for a multicentre randomised controlled tr... by Janus Christian Jakobsen, Anders Kehlet Nørskov, Mikkel Brabrand, Ole Mathiesen, Bjarke Viberg, Christian Rothe, Lars Hyldborg Lundstrøm, Kai Henrik Wiborg Lange, Stig Brorson, Christoffer Calov Jørgensen, Jonas Askø Andersen, Cecilie Dupont Harwood, Anne-Sofie Linde Jellestad, Aurelien-Xuan Rosendal Bahuet, Rasmus Linnebjerg Knudsen, Lana Chafranska Andersen, Per Hviid Gundtoft, Mads Terndrup

“…Introduction Distal radius fractures account for one-fifth of all fractures in the active elderly population and may cause chronic pain, loss of hand function and reduced work productivity, imposing a significant socioeconomic burden. …”
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Strategic multimodal intervention in at-risk elderly Indians for prevention of dementia (SMRUTHI INDIA): a cohort multiple randomised controlled trial (cmRCT) protocol by Pooja Sharma, Divyani Garg, Maroof Ahmad Khan, Ayush Agarwal, Manish Barvaliya, Shubham Gupta, Alex Rebello, Ashima Nehra, Anu Gupta, Padma Srivastava, Kritika Sharma, Subrata Baidya, Abhik Sinha, Shampa Das, Sunil Kumar Raina, Sakshi Sharma, Venugopalan Y Vishnu, Varuna Sharma, Subarna Roy, P K Anand, Nilima Nilima, Vaibhav Patil, Rajeev Aggarwal, Aditi Dubey, Hina Narzari, Sneha Sneha, Kamini Kashyap, Krishan Kaushal, Kajal Fulara, Shikha Chaudhary, Divya M R, Vasundhara Misra, Phaniraj Vastrad, Priyadarshanraj N, Sandesh J R, Harshath Ajay V, Aishwarya Bhovi, Mailrappa Padiyappa Hooli, Sagar P M, Ambika Y V, Ripanjit Singh, Naveen M R, Shilpa K, Sharanabasavaraj Devaramani, Sandip Bhattacharjee, Bishakha Sen, Shalina Jamatia, Manish Acharjee, Dipankar Deb, Pameli Jamatia, Munmun Debbarma, Shaily Bhushan, Rishabh Gautam, Rishav Bhatia, Arnav Verma, Kalpna Sharma, Gajraj Singh, Priyanka Kumari Meena, Akhilesh Nagar, Hitesh Tiwari, Tinku Yogi, Vikram Raigar, Vinny Wilson, Shradha Singh, Zubia Nasir, Daksha Kumari, Mallamma Duddagi, Basamma R Alur, Sreetama Bahaduri, Aditya Choudhary, Suhas Murali, Jyoti Kattna, Amita Sengupta, Dolan Roy, Tithi Patra, Bandana Kayestha, Yachana Sharma, Nandini Rawat, Kavita Bairwa, Muskan Sharma, Divyani Rathore

“…In parallel, the care bundle will be culturally and linguistically adapted and pilot-tested in 20 participants in each zone. …”
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Research priorities for children’s cancer: a James Lind Alliance Priority Setting Partnership in the UK by Nigel J Hall, David Weller, Bob Phillips, Faith Gibson, Susie Aldiss, Rachel Dommett, Jessica Elizabeth Morgan, Alex Brownsdon, Helen Morris, Julia Chisholm, Sonia Malik, Jonathan Gower, Andy Stewart, Dan Saunders, Ashley Ball-Gamble, Helen Hartley, Rachel Hollis, Scott Crowther, Jenni Hatton, Louise Henry, Loveday Langton, Kirsty Maddock, Keeley McEvoy, Simon Parke, Sue Picton, Rosa Reed-Berendt, Wendy Tarplee-Morris, Amy Walsh, Anna Watkins

“…Shortlisting via a second online survey identified the highest priority questions. A parallel process with children was undertaken. A final consensus workshop was held to determine the Top 10 priorities.Participants Children and survivors of childhood cancer, diagnosed before age 16, their families, friends and professionals who work with this population.Results Four hundred and eighty-eight people submitted 1299 potential questions. …”
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ENHANCE-D: protocol for a pragmatic, 3-arm, randomised controlled trial comparing the impact of enhanced smoking cessation interventions to very brief advice for adult smokers in d... by Richard Holliday, Nina Wilson, Vicky Ryan, Chrissie Butcher, Tara Homer, Philippa Watts, Dorcas Kareithi, Paul Blaylock, Laura Ternent, Roland Finch, Susan M. Bissett, Adam Todd, Helen Hancock, Fiona Ellwood, David I. Conway, Nicholas S. Jakubovics, Ralf Kist, Richard D. Holmes, Linda Bauld, Philip M. Preshaw, Elaine McColl

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DIAMONDS—a diabetes self-management intervention for people with severe mental illness: protocol for an individually randomised controlled multicentre trial by Tim Doran, Najma Siddiqi, Simon Gilbody, Rowena Jacobs, Patrick Doherty, Catherine Hewitt, Laura Mandefield, Simon Walker, Ian Kellar, Sarah Alderson, David Osborn, Vicki Johnson, Judith Watson, Gregor Russell, Steve Parrott, Jan Rasmus Boehnke, Peter A Coventry, Jinshuo Li, Richard Ian Gregory Holt, Judy Wright, David Shiers, Michelle Hadjiconstantinou, Keith Double, Claire Carswell, Jennifer V E Brown, Lucy Sheehan, Grace Catherine O’Carroll, Charlie Peck, R A Ajjan, Angela Ross, Mark Dawson

“…Introduction Type 2 diabetes mellitus (T2DM) is two to three times more common in people with severe mental illness (SMI) than in the general population. Supporting self-management in diabetes is fundamental to improving clinical outcomes. …”
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Maternal and neonatal outcomes of in-water and out-of-water births in low-obstetric-risk labour: a retrospective observational study at Piacenza hospital. by Elisa Piccolo, Giacomo Biasucci, Mariasole Magistrali, Belinda Benenati, Daniela Russo, Marina Paola Mercati, Sonia Tesoriati, Marina Cicalla, Simona Illari, Cristiana Pavesi, Maurizio Beretta, Marina Bolzoni

“…METHODS A retrospective observational cohort study employing a parallel design was undertaken. A total of 698 women with low-risk obstetric pregnancies were included and stratified into two groups based on the type of delivery. …”
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Telehealth-delivered cognitive rehabilitation for people with cognitive impairment as part of the post-COVID syndrome: protocol for a randomised controlled trial as part of the CIC... by Martina Vanova, Aysha Mohamed Rafik Patel, Iona Scott, Gina Gilpin, Emily N. Manning, Charlotte Ash, Philippa Wittenberg, Jason Lim, Zoe Hoare, Rachel Evans, Nathan Bray, Christopher M. Kipps, Ciara Devine, Saliha Ahmed, Ross Dunne, Anna Koniotes, Catherine Warren, Dennis Chan, Aida Suarez-Gonzalez

“…Methods This is a multi-centre, parallel-group, individually randomised controlled trial, comparing standard clinical care with and without cognitive rehabilitation. …”
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Clinical and cost-effectiveness of an online-delivered group-based pain management programme in improving pain-related disability for people with persistent pain—protocol for a non... by Anthony Dowell, Sarah Gerard Dean, Leigh Hale, Andrew R Gray, Tristram Ingham, Bernadette Jones, Cheryl Davies, Rebecca Grainger, William Leung, Meredith Perry, Hemakumar Devan, Dagmar Hempel, Jessica Mills, Barbara Saipe, Edward Shipton

“…Introduction Persistent non-cancer pain affects one in five adults and is more common in Māori—the Indigenous population of New Zealand (NZ), adults over 65 years, and people living in areas of high deprivation. …”
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Pharmacy Integrated Transitions (PIT) trial: a protocol for a pragmatic cluster-randomised crossover trial by Elizabeth Austin, Catherine Kim, Elizabeth J Austin, Giana H Davidson, Bryan A Comstock, Sarah E Monsell, Bryan Comstock, Mariam N Hantouli, Jocelyn Chaing, Arzu Ahmed Dervish, Nick J Gionet, Shalynn Howard, Nathalia Jimenez, Miriam Liberman, Edwin G Lindo, Zachary A Marcum, Thuan D Ong, Elina Serrano, Katherine Simons, Lydia S Sun, Oleg Zaslavsky

“…The trial aims to include a diverse patient population transitioning from hospitals to SNFs. The primary outcome is medication-related problems within 30 days posthospital discharge. …”
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Proposal for a revised Barthel index classification based on mortality risk assessment in functional dependence for basic activities of daily living by Vicente Martín Moreno, Vicente Martín Moreno, María Inmaculada Martínez Sanz, Amanda Martín Fernández, Sara Guerra Maroto, Eva Sevillano Fuentes, Elena Pérez Rico, Irene Sánchez González, Miriam Fernández Gallardo, Julia Herranz Hernando, María Palma Benítez Calderón, Laura Calderón Jiménez, Elena Sánchez Rodríguez, Miguel Recuero Vázquez, Helena Alonso Samperiz, Irene León Saiz, Juana Marcos Guerra

“…We propose its use as a screening test in parallel to the Barthel index. The study suggests that the Barthel Index may have limitations in adequately discriminating mortality risk.…”
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Web-Based Application for Reducing Methamphetamine Use Among Aboriginal and Torres Strait Islander People: Randomized Waitlist Controlled Trial by Rachel Reilly, Rebecca McKetin, Federica Barzi, Tayla Degan, Nadine Ezard, Katherine Conigrave, Julia Butt, Yvette Roe, Handan Wand, Brendan Quinn, Wade Longbottom, Carla Treloar, Adrian Dunlop, James Ward

“…Future web-based apps for this population need to consider methods to increase participant engagement. …”
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Statistical analysis plan for the 24-week randomised trial of hypoglycaemia prevention, awareness of symptoms, and treatment: HypoPAST by Sharmala Thuraisingam, Jennifer A. Halliday, Uffe Søholm, Elizabeth Holmes-Truscott, Christel Hendrieckx, Timothy C. Skinner, Vincent L. Versace, Jane Speight

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Les réseaux d’alimentation en eau des pentes de la Croix-Rousse et de la presqu’île de Lyon by Jules Ramona

“…However, the nature of their relationship (parallel or hierarchical?) needs to be clarified. Dedicated to thermal activities or to the supply of fountains, the presence of a forced water system suggests the existence of an imposing and complex public supply system.Lastly, the analysis of the hydraulic installations of use can be used to attempt a classification according to supply modes. …”
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Text message intervention delivered from Australian general practices to improve breast cancer survivors’ physical activity and cardiovascular risk factors: protocol for the EMPOWE... by Karice K Hyun, Christine Mitchell, Julie Redfern, Nashid Hafiz, Rebecca Raeside, Brooke Nickel, Carolyn Ee, Jennifer McIntosh, Elisabeth Elder, Raymond J Chan, David Mizrahi, Stephanie R Partridge, Anna C Singleton, Allyson Ruth Todd, Kirsty E Stuart

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Efficacy of the cigarette-burning application combined with medication intervention for smoking cessation in China: A randomized controlled trial by Xiao-Wen Wei, Rui Qin, Yong-Zhuang Liu, Zhao Liu, An-Qi Cheng, Xin-Mei Zhou, Zheng Su, Zi-Yang Cui, Jin-Xuan Li, Liang Zhao, Dan Xiao, Chen Wang

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Comparative efficacy and safety of adalimumab biosimilar (BCD-057) and innovator in patients with psoriasis vulgaris. Results of the BCD-057-2/CALYPSO phase III international, mult... by Т. V. Korotaeva, A. V. Samtsov, A. L. Bakulev, M. M. Kokhan, I. K. Minullin, O. A. Vylegzhanina, V. V. Dubensky, B. V. Khalilov, A. A. Khotko, O. S. Zykova, I. V. Chumachenko, A. M. Lukyanov, A. V. Artemyeva, S. I. Derbin, E. Yu. Stukalina, E. V. Chernyaeva, R. A. Ivanov

“…Immunogenicity was determined using the validated test of patient serum samples for binding antibodies (BAb) and neutralizing antibodies.Results and discussion. The per-protocol population for efficacy evaluation included 342 patients. …”
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The Privatisation of a National Project by Gabriel Schwake

“…Consequently, the architectural and urban features of these settlements were parallel to the ruling political, economic and social values and were thus characterised by reproduced homogeneous and economical residential environments. …”
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Analysis of the dynamic correlation between chronic comorbidities and health shocks among middle-aged and older adults people in rural mountainous areas of southern Ningxia—from 14... by Juan Yang, Juan Yang, Shan Liu, Shan Liu, Fei Li, Fei Li, Haodong Meng, Haodong Meng, Hui Qiao, Hui Qiao, Yongxin Xie, Yongxin Xie

“…Meanwhile, it is also necessary to closely monitor health shock events, and accordingly optimize the management strategies for chronic comorbidities, thereby reducing the incidence of health shocks among the middle-aged and older adults population, improving the quality of life and health, and promoting the realization of the goal of healthy aging.…”
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