Characterizing Cross-Provincial High-Cost Patients in Rural China: Cross-Sectional Study by Minjiang Guo, Xiaotong Jiang, Yang Liu, Yang Liu, Fangyuan Zhang, Zhongyuan Zhang, Yazi Li

“…In China, approximately 95% of rural residents are covered by Urban and Rural Resident Basic Medical Insurance. In parallel, increasing population mobility has made it more common for rural residents to seek medical treatment and claim reimbursements across provincial boundaries. …”
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Clinical and economic effectiveness of Schroth therapy in adolescent idiopathic scoliosis: insights from a machine learning- and active learning-based real-world study by Erdal Ayvaz, Merve Uca, Ednan Ayvaz, Zafer Yıldız

“…Abstract Background Adolescent idiopathic scoliosis (AIS) is a prevalent musculoskeletal condition affecting approximately 2–3% of the adolescent population. Although exercise-based therapeutic interventions are increasingly employed as non-surgical alternatives, their clinical and economic effectiveness remains underexplored in real-world settings. …”
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Efficacy of pharmacological and non-pharmacological therapy on chronic cancer pain intensity of adults with cancer: A network meta-analysis protocol. by Wenhao Su, Xueling Li, Yanru Wang

“…The final analysis results may be significantly heterogeneous, because the population with cancerous pain suffers from different types of cancers. …”
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Multicentre, open-label, randomised, controlled trial to compare early intervention with calcimimetics and conventional therapy in preventing coronary artery calcification in patie... by Yukio Yuzawa, Daijo Inaguma, Soshiro Ogata, Hideki Kawai, Yoshitaka Tatematsu, Naoki Okamoto, Eiichi Watanabe, Midori Hasegawa, Naotake Tsuboi

“…Therefore, this study will evaluate the efficacy and safety of early intervention with upacicalcet, a calcimimetic used to prevent coronary artery calcification in this patient population.Methods and analysis This multicentre, open-label, randomised, parallel-group controlled study will compare an early intervention group, which received upacicalcet and a low-dose VDRA, with a conventional therapy group, which received a VDRA. …”
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Pregnant women’s perceptions of antenatal care and utilisation of digital health tools in Magu District, Tanzania: a qualitative study by Sandra van Pelt, Marit van der Pijl, Robert A.C. Ruiter, Pendo M. Ndaki, Rehema Kilimba, Laura Shields-Zeeman, John B.F. de Wit, Karlijn Massar

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Mutation screening of retinal dystrophy patients by targeted capture from tagged pooled DNAs and next generation sequencing. by Christopher M Watson, Mohammed El-Asrag, David A Parry, Joanne E Morgan, Clare V Logan, Ian M Carr, Eamonn Sheridan, Ruth Charlton, Colin A Johnson, Graham Taylor, Carmel Toomes, Martin McKibbin, Chris F Inglehearn, Manir Ali

“…Prior to the development of massively parallel sequencing, comprehensive genetic screening was unobtainable for most patients. …”
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Topical olive oil is not inferior to hyperoxygenated fatty aids to prevent pressure ulcers in high-risk immobilised patients in home care. Results of a multicentre randomised tripl... by Inmaculada Lupiañez-Perez, Shakira Kaknani Uttumchandani, Juan Carlos Morilla-Herrera, Francisco Javier Martin-Santos, Magdalena Cuevas Fernandez-Gallego, Francisco Javier Navarro-Moya, Yolanda Lupiañez-Perez, Eugenio Contreras-Fernandez, Jose Miguel Morales-Asencio

“…Design: Non-inferiority, triple-blind, parallel, multicentre, randomised clinical trial. Scope: Population attending Primary Healthcare Centres in Andalusia (Spain). …”
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Study protocol for a stepped-wedge, randomized controlled trial to evaluate implementation of a suicide risk identification model among behavioral health patients in three large he... by Scott P. Stumbo, Stephanie A. Hooker, Rebecca C. Rossom, Kathleen Miley, Brian K. Ahmedani, Elizabeth Lockhart, Hsueh-Han Yeh, Bobbi Jo H. Yarborough

“…A stepped-wedge design using repeated measures pre/post-implementation maximizes statistical efficiency and power with fewer participants compared to a parallel design while allowing all clinics to participate. …”
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Comparative study on the depression, anxiety, and some risk factors among different nationalities during the coronavirus disease 2019 pandemic: a cross-sectional study by Walaa A. Fouad, Thanaa M. Rabah, Asmaa M. Fathy, Sherif M. Eldeeb, Doaa E. Ahmed, Ahmed Aboulghate, Ghada A. Abdellatif, Amira Mohsen, Dalia M. Elmosalami, Rehan M. Saleh, Hala A. Amer, Iman I. Salama, Aida M. Abdelmohsen, Fardos S. Bayomi, Somaia I. Salama, Lobna A. El Etreby, Samia M. Sami, Fatma A. Shaaban, Hanaa Emam, Hazem M. El-Hariri

“…The viral pandemic may be triggered by a parallel shadow pandemic of mental illness, including corona-phobia in adults and children. …”
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Effectiveness of Peer Support on Foot Self-Care Practices among Diabetic Patients in Western Kenya by Lucy Kavinguha, Tecla Sum, John Okoth, Morris Senghor

“… Context: The global burden of diabetes is steadily rising with a parallel increase in related complications. Individuals with chronic conditions such as diabetes need assistance in learning, mastering, and sustaining complex self-care practices that support healthy living and prevent the development of complications. …”
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Optimizing Recruitment and Retention in Cancer Clinical Trials in Low-Resource Settings: Barriers and Facilitators From Nigerian Provider's Perspectives by Babayemi O. Olakunde, Ngozi Idemili-Aronu, Tara M. Friebel-Klingner, Adaeze Chike-Okoli, Ijeoma U. Itanyi, Tonia C. Onyeka, Kimberly Levinson, Anne F. Rositch, Richard B.S. Roden, Tzyy-Choou Wu, Echezona E. Ezeanolue

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Exercise Identity and Spiritual Well-Being in Nursing Home Residents: Mediating Roles of Social Support and Exercise Behavior in Hebei Province, China by Luo S, Wu LM, Wang Y, Jin HQ, Zhao YN, Du XF

“…Exercise behavior also partially mediated the relationship between exercise identity and Spiritual well-being, with an indirect effect value of 0.201, accounting for 33.5% of the total effect (0.599).Conclusion: Perceived social support and exercise behavior have parallel mediating effects on the relationship between exercise identity and Spiritual well-being of older adults residing in nursing homes. …”
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Current state of medication treatment practice for heart failure with reduced ejection fraction among cardiologists in Japan: a survey on the relationship between satisfaction leve... by Satoru Hashimoto, Yoshihiro Motozawa, Toshiki Mano

“…Abstract Background The number of patients with heart failure is steadily increasing in parallel with the aging of the population in Japan. …”
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Antibody response to Plasmodium vivax in the context of Epstein-Barr virus (EBV) co-infection: A 14-year follow-up study in the Amazon rainforest. by Luiz F F Guimarães, Bárbara A Rodrigues, Michelle H F Dias, Matheus G Barcelos, Maria F A Nascimento, Sâmick L Moreira-Nascimento, Sofia L Afonso, Barbara G S Abreu, Jaap M Middeldorp, Francis B Ntumngia, John H Adams, Camila Fabbri, Stefanie Lopes, Cor J F Fernandes, Flora S Kano, Luzia H Carvalho

“…<h4>Conclusions/significance</h4>In an immunocompetent P. vivax-exposed adult population neither sporadic episodes of EBV-DNAemia nor antibody responses to lytic/latent EBV antigens influence the longevity of both strain-specific and strain-transcending DBPII immune responses. …”
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Cross-sectional and longitudinal trajectory analyses of sleep duration and frailty among middle-aged and older Chinese adults by Wei Zheng, Yan Sun, Xianling Liu, Miao Lu, Di Xu

“…Abstract The relationship between sleep duration and frailty remains unclear, particularly regarding their bidirectional nature and temporal dynamics in the Chinese population. This study aimed to investigate the cross-sectional association, developmental trajectories, and interactions between sleep duration and frailty in Chinese middle-aged and older adults. …”
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Survey of Hand Hygiene, High-Touch Device Use, and Proper Habits of Health Care Workers for Infection Risk Prevention: Protocol for a Cross-Sectional Study by Antonio Aprile, Giustino Morlino, Claudia Mosconi, Luca Guarente, Alessandra Messina, Mariachiara Carestia, Patrizia De Filippis, Francesca Pica, Massimo Maurici, Leonardo Palombi

“…Sampling will be conducted quarterly (first 2 weeks of each quarter) to assess any changes in microbial flora. In parallel, an Italian version of the World Health Organization questionnaire on health care workers’ knowledge of hand hygiene and a questionnaire on the use of high-touch devices will be administered to participants. …”
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Lifestyle Advice Combined with Personalized Estimates of Genetic or Phenotypic Risk of Type 2 Diabetes, and Objectively Measured Physical Activity: A Randomized Controlled Trial. by Job G Godino, Esther M F van Sluijs, Theresa M Marteau, Stephen Sutton, Stephen J Sharp, Simon J Griffin

“…We examined the effect of communicating an estimate of genetic or phenotypic risk of type 2 diabetes in a parallel group, open, randomized controlled trial.<h4>Methods and findings</h4>We recruited 569 healthy middle-aged adults from the Fenland Study, an ongoing population-based, observational study in the east of England (Cambridgeshire, UK). …”
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Three siblings with giant axonal neuropathy caused by a novel variant in GAN gene: the first report from Egypt by Abdelrahim A. Sadek, Mohammed A. Aladawy, Tarek M. M. Mansour, Ali Farag El Hadad, Abd Elaziz Shokry, Rin Khang, Seung Woo Ryu, Elsayed Abdelkreem

“…The extent of brain imaging abnormalities paralleled the clinical severity as case 1 had only moderate white matter changes while case 2 showed extensive white matter lesions, ventriculomegaly, and atrophic changes. …”
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Standing genetic variation and introgression shape the cryptic radiation of Aquilegia in the mountains of Southwest China by Jun-Chu Peng, Ziwen He, Zhi-Qiang Zhang

“…Using whole-genome resequencing of 158 individuals from 23 natural populations, we identify three to four paraphyletic lineages within each morphological species. …”
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Measles immune suppression: lessons from the macaque model. by Rory D de Vries, Stephen McQuaid, Geert van Amerongen, Selma Yüksel, R Joyce Verburgh, Albert D M E Osterhaus, W Paul Duprex, Rik L de Swart

“…Histopathological analysis of lymphoid tissues showed lymphocyte depletion in the B- and T-cell areas in the absence of apoptotic cells, paralleled by infiltration of T-lymphocytes into B-cell follicles and reappearance of proliferating cells. …”
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