Effectiveness of task-oriented circuit training on the motor performance of ischaemic stroke patients: a study protocol for randomised clinical trial by Mohammad Anwar Hossain, Harun Or Rashid, Farzana Sharmin, Abid Hasan Khan, Farjana Sharmin, Md Forhad Hossain, Mahdi Ul Bari, Md Ershad Ali, Arnob Datta, Saiba Muhammad Sabrin, Md Rezaul Karim

“…With the rapidly growing stroke survivor population, it is crucial to identify an effective method for their healthcare. …”
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Regenerative therapies in lichen sclerosus genitalis patients and possible efficacy in preventing squamous cell carcinoma development: a long-term follow-up pilot study by Marinella Tedesco, Barbara Bellei, Lavinia Alei, Monia Di Prete, Carlo Cota, Tiziano Pallara, Antonio Bonadies, Alessandra Latini, Stefania De Fazio, Emilia Migliano

“…LS patients are at higher risk of developing squamous cell carcinoma (SCC) in their lifetime compared to the general population. Through a retrospective study, we evaluated the impact of regenerative medicinebased therapies on SCC onset in the context of genital LS. …”
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Effects of ω-3 PUFAs Supplementation on Myocardial Function and Oxidative Stress Markers in Typical Rett Syndrome by Silvia Maffei, Claudio De Felice, Pierpaolo Cannarile, Silvia Leoncini, Cinzia Signorini, Alessandra Pecorelli, Barbara Montomoli, Stefano Lunghetti, Lucia Ciccoli, Thierry Durand, Roberto Favilli, Joussef Hayek

“…/day) versus the remaining half untreated population. Echocardiographic systolic longitudinal parameters of both ventricles, but not biventricular diastolic measures, improved following ω-3 PUFAs supplementation, with a parallel decrease in the OS markers levels. …”
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Circadian rest-activity rhythms and multimorbidity and mortality risks among menopausal women: a trajectory analysis of a UK Biobank cohort by Xiyun Ren, Wentong Wang, Wei Li, Lishuang Sun, Tianyu Liu, Haibo Zhou, Tianshu Han, Changhao Sun, Xiangfeng Lu, Wenjing Tian

“…Objectives We examined relationships between circadian rest-activity rhythms (CRARs) and multimorbidity progression in this population. Methods We used UK Biobank data, involving 10,138 participants, who were initially free of chronic conditions. …”
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From grit to flourishing: physical literacy’s mediating role in enhancing well-being among college students with obesity by Xingyu Liu, Zidong Li, Wanru Cheng, Jian Zhang, Xiaoyu Ma, Di Tang, Jinde Liu, Tianyu Gao, Ting Liu, Tao Chen, Ruisi Ma

“…A multifaceted approach that fosters both psychological traits and physical competencies may prove beneficial in improving the psychological and physical health of this population.…”
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GeNepher data- and biobank for patients with (suspected) genetic kidney disease: Rationale, design and status update by Laura R. Claus, Iris Lekkerkerker, Bert van der Zwaag, Tri Q. Nguyen, Nine V.A.M. Knoers, Martin H. de Borst, Maarten B. Rookmaker, Marc R. Lilien, Albertien M. van Eerde

“…With a tiered approach participants can give broad consent for including their 1) available medical data (including genetic testing results), 2) inclusion of massively parallel sequencing data for add-on analysis, and 3) additional biobank sampling (e.g. urine for tubuloids, skin biopsy for fibroblasts). …”
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Respiratory muscle training improves aerobic capacity and respiratory muscle strength in youth wrestlers by Mehmet Ismail Tosun, Erkan Demirkan, Abdurrahim Kaplan, Yasemin Ari Yilmaz, Irem Eker Arici, Michael Favre, Veysi Aslan, Mehmet Kutlu

“…This study aimed to investigate the effects of RMT on respiratory muscle strength and aerobic endurance in youth wrestlers.MethodsA parallel-grouperal was conducted across 22 male youth wrestlers aged 14.8 ± 0.4 years. …”
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A Randomised Trial Examining Cardiovascular Morbidity and All-Cause Mortality 24 years Following General Health Checks: the Ebeltoft Health Promotion Project (EHPP) by Martin Bernstorff, Pia Deichgræber, Niels Henrik Bruun, Else-Marie Dalsgaard, Morten Fenger-Grøn, Torsten Lauritzen

“…General health checks have been suggested to facilitate this process.Objectives To examine the long-term effect of population-based general health checks on CVD and all-cause mortality.Design and setting The Ebeltoft Health Promotion Project (EHPP) is a parallel randomised controlled trial in a Danish primary care setting.Participants The EHPP enrolled individuals registered in the Civil Registration System as (1) inhabitants of Ebeltoft municipality, (2) registered with a general practitioner (GP) participating in the study and (3) aged 30–49 on 1 January 1991. …”
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Development, validation, and application of a dual-color fluorescent assay for high-throughput screening of anti-chikungunya drugs by Pattadon Sawetpiyakul, Duangpron Peypala, Pathaphon Wiriwithya, Gridsada Phanomchoeng, Tanatorn Khotavivattana, Warintorn Chavasiri, Sittiporn Pattaradilokrat, Siwaporn Boonyasuppayakorn

“…Abstract Chikungunya virus (CHIKV), one of the arthropod-borne viruses, has been affecting the global population for more than 70 years since it was first described with more than 620,000 cases in 2024 alone. …”
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BACK TO THE “GOLD STANDARD”: HOW PRECISE IS HEMATOCRIT DETECTION TODAY? by Leonid Livshits, Tal Bilu, Sari Peretz, Anna Bogdanova, Max Gassmann, Harel Eitam, Ariel Koren, Carina Levin

“…Methods: 223 blood samples from the "general population" and 19 from sickle cell disease patients were examined in parallel for hematocrit values using the automated HCT, standard "micro-HCT" and "ImageJ" micro-HCT methods. …”
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Comparative Analysis of the Diversity of SARS-CoV-2 Lines Circulating in Omsk Region in 2020–2022 by E. A. Gradoboeva, Zh. S. Tyulko, A. V. Fadeev, A. G. Yakimenko, V. V. Yakimenko

“…However, this does not exclude the parallel occurrence of certain mutations in remote territories from each other.…”
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Protocol MelatoSom-Kids-PTSD: sleep disturbances in children and adolescents with post-traumatic stress disorder (PTSD) – a randomized double-blind placebo-controlled trial to inve... by Julie Rolling, Eve Reynaud, Amaury C. Mengin, Thomas Zanfonato, Patrice Bourgin, Carmen M. Schroder

“…Secondary endpoints will be the differences in objective sleep quality parameters and daytime functioning before and after treatment, in children with PTSD and their caregivers.Discussion: This paper describes the MelatoSOM-Kids-PTSD protocol, which will evaluate the effectiveness of melatonin, a treatment that has already demonstrated an excellent benefit-risk ratio in the paediatric population over 4 years.…”
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An unusual mortality event for bottlenose dolphins links to altered diets resulting from ecological changes by Megan K. Stolen, Wendy Noke Durden, Teresa Jablonski, Graham A. J. Worthy, Richard Paperno, Charles A. Jacoby

“…The changes in diet reflected availability of prey, with a fisheries independent monitoring program yielding parallel changes in catches of sea bream and ladyfish. …”
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Evaluation of the efficacy of integrating digital therapeutics with home-based cardiac rehabilitation on cardiovascular health in high-risk post-PCI patients (DTx-HBCR): Study prot... by Shuangliang Ma, Zhongxiu Chen, Junyan Zhang, Jiani Liu, Lin Xu, Baotao Huang, Mingang Zhou, Hua Wang, Yong Chen, Mian Wang, Chen Li, Yong He

“…Methods The DTx-HBCR trial is a parallel-arm, randomized controlled trial that will enroll 366 high-risk patients undergoing PCI at West China Hospital of Sichuan University. …”
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Evidence synthesis in neuromyelitis optica spectrum disorders: modeling a clinical trial based on published data by D. G. Tolkacheva, I. V. Fateev, K. V. Sapozhnikov, O. N. Mironenko, A. A. Lazarev, V. D. Batorova, A. A. Porozova, A. V. Zinkina-Orikhan

“…According to its results, for the expected BCD-132-6/AQUARELLE population, a 6-month ARR of 0.116 (95 % CI: 0.030–0.212) was predicted for anti-CD20 therapy. …”
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Associations of circadian syndrome with gout and hyperuricemia: a cross‑sectional analysis of NHANES 2007–2018 by Jun-Wei Ren, Jia-Hao Wang, Yun-Fei Xiao, Yun-Jin Bai, Ping Han

“…Conclusion This study identified that CircS was significantly associated with both gout and hyperuricemia in the US general population. The risk of these conditions increased in parallel with rising CircS scores. …”
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Comparison of Two Manual Therapy Programs, including Tendon Gliding Exercises as a Common Adjunct, While Managing the Participants with Chronic Carpal Tunnel Syndrome by Fauzia Javed Sheereen, Bibhuti Sarkar, Pallavi Sahay, Mohammad Abu Shaphe, Ahmad H. Alghadir, Amir Iqbal, Taimul Ali, Fuzail Ahmad

“…The study followed a two-arm parallel-group randomized comparative design. Thirty participants (aged 30–59 years) with chronic CTS were recruited randomly to both the NT and CBMT groups. …”
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A mobile-based randomized controlled trial on the feasibility and effectiveness of screening for major depressive disorder: study protocol by M. M. E. Zandbergen, E. E. L. Jansen, L. J. Jabbarian, H. J. de Koning, I. M. C. M. de Kok

“…Methods This study will be a three-arm, parallel randomized control trial (RCT) performed in a multi-ethnic population within the municipality of Rotterdam (the Netherlands). …”
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Japi 2.0, a gaming platform to stimulate cognitive and non-cognitive skills in early childhood: protocol for a pilot randomized controlled trial by Jorge Gaete, Saray Ramírez, Cristian A. Rojas-Barahona, Valentina Romo, Natalia Ríos, Ricardo Araya

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Investigating the effect of mindfulness-based art therapy on self-efficacy of multiparous and nulliparous women: A randomized controlled trial by Ashraf Beirami, Zahra Rahemi

“…Methods: The present study was a randomized clinical trial with three parallel intervention arms (multiparous and nulliparous groups) and a control. …”
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