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Methylene Blue in Ventilator-Induced Lung Injury after Pneumonectomy: an Experimental Study
Published 2007-06-01“…After measurement of the parameters of systemic hemodynamics and extravascular water of the lung (EVWL), the animals were divided into 3 groups: 1) a control group (CG, n=7) with a tidal volume (TV) of 6 ml/kg and an end-expiratory positive pressure (PEEP) of 2 cm H2O; 2) a VILI group (n=9) with a TV of 12 ml/kg and a PEEP of 0 cm H2O; 3) a group of MB (n=7) that was given in parallel with a damaging ventilation mode. The thermodilution technique (using a Cold Z-021 monitor, (Pulsion, Germany)) was employed to measure volumetric parameters and EVWL. …”
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102
Potential induction of the relative mRNA expression levels of CYP450 by Zhicaowu-Hezi (Aconiti kusnezoffii radix preparata and Terminalia chebula Retz.)
Published 2025-07-01“…Rats received 14-day oral administrations of either Zhicaowu, Hezi, or their combinations (1:1, 1:3, 3:1 ratios), followed by comprehensive assessment using: (1) cocktail probe drug assays monitoring seven CYP450 isoforms (CYP1a2, 2b1, 2c11, 2c13, 2d2, 2e1, 3a1) with HPLC quantification methods for substrate detection, (2) RT-qPCR analysis of hepatic CYP450 mRNA expression, and (3) parallel in vitro studies employing rat liver microsomes to verify enzyme activity changes. …”
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103
Effect of CYP3A4 inhibitor and induction on the pharmacokinetics and safety of FHND9041, a novel EGFR T790M inhibitor, in healthy Chinese
Published 2025-05-01“…Caution is advised when FHND9041 is co-administered with Itraconazole or other strong CYP3A4 inhibitors. Close monitoring of tolerability during co-administration is essential, and dose reduction may be necessary if required. …”
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Molecular biological and ultrasonic methods in the evaluation of the effectiveness of drug therapy in patients with cervical cancer and ovarian cancer
Published 2014-07-01“…This paper analyzes the data of complex clinical, ultrasound and pathological study of 86 patients, was 2 groups of patients – 58 women with locally advanced cervical cancer (IIb–IIIb stages) and 28 patients with ovarian cancer (IIa−IV stages).During the morphological and ultrasonic parallels found a direct correlation between the degree of drug and the amount pathomorphism tumor focus, a reduction of vascularization and blood flow velocity.…”
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106
Adaptive Just-in-Time Intervention to Reduce Everyday Stress Responses: Protocol for a Randomized Controlled Trial
Published 2025-01-01“…Participants enrolled in both conditions will engage in self-monitoring for the entire study period and have access to a general stress management education module. …”
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107
Improving transparency in malaria programme funds: A business case for connected diagnostics in Kenya
Published 2024-11-01“…Based on these insights, we estimated a 25% reduction in costs can be realised, while simultaneously better quality indicators can be monitored. …”
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108
[Translated article] AVIP project (Prosthetic Virtual Friend): Study of clinical–functional outcomes and satisfaction with a mobile application in the perioperative management and...
Published 2025-03-01“…Material and method: Randomised clinical trial with parallel groups involving patients with an indication for THA. …”
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Proyecto AVIP (Amigo VIrtual Protésico): estudio de resultados clínico-funcionales y de satisfacción con una aplicación móvil en el manejo perioperatorio y seguimiento de implantes...
Published 2025-03-01“…Material and method: Randomized clinical trial with parallel groups involving patients with an indication for THA. …”
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110
Iris: A Next Generation Digital Pathology Rendering Engine
Published 2025-01-01“…This buffering rate allows for an entirely new field of view to be fully buffered and rendered in less than a single monitor refresh on a standard display, and high detail features within 2–3 monitor refresh frames. …”
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INFLUENCE OF TIME MODES OF THERMAL TREATMENT ON Pt-Si SYSTEM MICROSTRUCTURE
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113
The Main Forms of Advanced Training of Soviet Censors in the Second Half of the 1940s (proceeding from the materials of the State Archives of Kirovohrad Oblast)
Published 2023-12-01“…Several forms of advanced training were applied in parallel, namely: professional training, seminars, meetings of censorship workers (at regional, republican and all-Union levels) and the party education system. …”
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Pilot study of extended-release lorcaserin for cocaine use disorder among men who have sex with men: A double-blind, placebo-controlled randomized trial.
Published 2021-01-01“…Lorcaserin was not associated with significant reductions in cocaine use by urine testing, but was associated with significant reductions in self-reported cocaine use. …”
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116
An unusual mortality event for bottlenose dolphins links to altered diets resulting from ecological changes
Published 2025-04-01“…The changes in diet reflected availability of prey, with a fisheries independent monitoring program yielding parallel changes in catches of sea bream and ladyfish. …”
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117
Smart Learning Ecosystems beyond 2030
Published 2025-05-01“…An effort that was conducted in parallel to the definition of the SDGs by the UNESCO that included also SDG 4 [5] aimed at ensuring access to quality, equitable and inclusive education for all, a sine qua non for promoting sustainable development. …”
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118
Hybrid closed-loop systems for managing blood glucose levels in type 1 diabetes: a systematic review and economic modelling
Published 2024-12-01“…Interventions to manage diabetes include education, continuous glucose monitoring (including a sensor, transmitter and display device) and insulin therapy [multiple daily injections or continuous subcutaneous insulin infusion (CSII)]. …”
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119
Preventive administration of shengmaiyin: a novel approach to counteract heatstroke-induced coagulopathy in rats
Published 2025-03-01“…Plasma samples were subjected to data-independent acquisition (DIA)-based quantitative proteomics analysis, and differentially expressed proteins identified were further authenticated using parallel reaction monitoring (PRM) and Enzyme-Linked Immunosorbent Assay (ELISA).ResultsThe SMY group exhibited a significantly extended running distance and time before reaching a core temperature of 42°C compared to the EHS group. …”
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Improved RT-DETR for Infrared Ship Detection Based on Multi-Attention and Feature Fusion
Published 2024-11-01“…The model incorporates a novel backbone by integrating CSP and parallelized patch-aware attention to enhance sensitivity to infrared imagery. …”
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