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  1. 21

    Sonographic postpartum anal sphincter defects and the association with pelvic floor pain and dyspareunia by Malin Huber, Charlotta Larsson, Jan‐P Lehmann, Karin Strigård, Anna Lindam, Katarina Tunón

    Published 2023-10-01
    “…Anal sphincters were assessed with 3D‐EAUS 3 months postpartum, and self‐reported pelvic floor function data were obtained using a web‐based questionnaire distributed 1 year after delivery. …”
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    Article
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    THE RENIN-ANGIOTENSIN SYSTEM AND ITS INVOLVEMENT IN PAIN CONTROL. A NEW INSIGHT INTO AN OLD SYSTEM by Daniela Pechlivanova, Dimo Angelov, Elena Dzhambazova

    Published 2025-04-01
    “…Accumulating data however enlarged scientific knowledge on the role of RAS in control of brain functions and modulation of pain susceptibility. Scientific evidence indicates a differential involvement of angiotensin receptors in the modulation of pain transmission and suppression. …”
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    Article
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    Association of visceral adiposity index and chronic pain in US adults: a cross-sectional study by Weilong Xu, Ruizhen Shi, Youzhuang Zhu, Wei Feng

    Published 2025-03-01
    “…Abstract The Visceral Obesity Index (VAI) is utilized as a metric employed to assess the distribution of abdominal adipose tissue as well as the functional status of adipose tissue. …”
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  8. 28

    Lumbar Temperature Map of Elderly Individuals with Chronic Low Back Pain—An Infrared Thermographic Analysis by Nelson Albuquerque, Liliana Gonçalves, Wally Strasse, Joaquim Gabriel, Laetitia Teixeira, Pedro Cantista

    Published 2025-05-01
    “…However, its applicability in clinical practice and correlation with functional and pain-related parameters remain unclear. …”
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    Article
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    Efficacy of Combined High-Intensity Laser Therapy and Collagenase Chemonucleolysis in Lumbar Disc Herniation Management: a Prospective Randomized Controlled Trial by Peng Song, Chao Ma, Chenchen Xu, Yongjun Zhang, Yan Yuan

    Published 2025-06-01
    “…Conclusions Our findings demonstrate that high-intensity laser therapy augmentation of collagenase chemonucleolysis significantly improves early postoperative pain and functional outcomes in patients with lumbar disc herniation. …”
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    Article
  10. 30

    Therapeutic effects of teriparatide on subchondral bone lesions and pain in mono-iodoacetate-induced osteoarthritis rat model by Koji Aso, Natsuki Sugimura, Masashi Izumi, Ikeuchi Masahiko

    Published 2025-09-01
    “…Subchondral bone pathology scores were significantly correlated with asymmetric weight distribution. Conclusion: TPTD attenuated subchondral bone lesions and improved weight-bearing function in MIA-induced OA, highlighting its therapeutic potential in OA-related pain.…”
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    Minimal Clinically Important Difference in Patients with Acute Neck Pain Undergoing Conservative Treatment with Korean Medicine by Kim JS, Kim E, Shin S, Ha IH, Lee YJ

    Published 2025-07-01
    “…The MCID and SCB of pain, functional disability, and quality of life were assessed using anchor-based methods. …”
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    Article
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    Preclinical Animal Models to Investigate the Role of Na<sub>v</sub>1.7 Ion Channels in Pain by Alvaro Yogi, Umberto Banderali, Maria J. Moreno, Marzia Martina

    Published 2025-04-01
    “…Voltage-gated sodium channels (Na<sub>v</sub>s) are major drivers of the excitability of sensory neurons, and the Na<sub>v</sub> subtype 1.7 (Na<sub>v</sub>1.7) has been shown to be critical for the transmission of pain-related signaling. This is highlighted by demonstrations that gain-of-function mutations in the Na<sub>v</sub>1.7 gene SCN9A result in various pain pathologies, whereas loss-of-function mutations cause complete insensitivity to pain. …”
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    Critical Role of p38&alpha; MAPK Subclass in the Development of Pain Hypersensitivity After Hind Paw Incision by Ishikawa D, Yamakita S, Oh-Hashi K, Amaya F

    Published 2025-02-01
    “…The present animal study explored the function of four p38 mitogen-activated protein kinase (MAPK) subclasses (α, β, γ, and δ) in dorsal root ganglion (DRG) in the development of post-incisional pain hypersensitivity.Methods: The amount of p38 MAPK subclass mRNA in the DRG of male Sprague-Dawley rats was quantified using real-time PCR. …”
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    Carrier rocket-inspired hydrogel microspheres targeting subchondral bone osteoclast activity alleviate osteoarthritic pain and cartilage degeneration by Zhenglin Zhu, Yujia Luo, Pengcheng Xiao, Yi Xie, Jun Zhang, Ke Huang, Xiangdong Wu, Ke Lu, Yuting Zhang, Jianye Tan, Hong Chen, Wei Huang, Yiting Lei, Junyi Liao

    Published 2025-08-01
    “…Abstract Background Osteoarthritis (OA) represents a major global health challenge, characterized by progressive cartilage degeneration and subchondral bone remodeling, which culminate in debilitating pain and functional impairment. While recent studies have underscored the pivotal role of activated osteoclasts in the pathogenesis of OA and its associated pain, the therapeutic potential of intra-articular drug delivery has been hindered by challenges such as rapid synovial clearance and the poor permeability of cartilage, limiting the effective inhibition of subchondral osteoclast activity. …”
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    Towards the Real-World Analysis of Lumbar Spine Standing Posture in Individuals with Low Back Pain: A Cross-Sectional Observational Study by Elena Muñoz-Gómez, Frederick McClintock, Andrew Callaway, Carol Clark, Raee Alqhtani, Jonathan Williams

    Published 2025-05-01
    “…Analysis of standing posture across time included variability, fidgeting, and amplitude probability distribution function analysis. The study demonstrated that accelerometers are a valid method for extracting standing posture from everyday activity data. …”
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