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CS03 | Khorana risk score and genomic profiling for prediction of venous thromboembolism in ovarian cancer
Published 2025-08-01“…Methods: We included patients with OC consecutively enrolled in the Comprehensive Genomic Profiling (CGP) program (NCT 06020625) at Gemelli University Polyclinic Foundation IRCCS between March 2022 and December 2023. …”
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1165
Macrophage Polarization in Myocardial Ischemia‒Reperfusion Injury: Pathophysiology and Therapeutic Targets
Published 2025-07-01“…In addition, macrophages play a key intersection role in multiple pathological mechanisms, including but not limited to, the regulation of oxidative stress, the drive of programmed cell death, and the remodeling of the microenvironment. …”
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1166
Modeling of the internal structure of a spherical graphite inclusion in ductile cast iron and its behavior under loading
Published 2025-01-01“…According to one of the versions, it is a complex combination of oxides, sulfides and oxysulphides, the outer layer of this particle being coherent with the graphite lattice; according to another version, it is a particle of siliceous ferrite. …”
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1167
Astragaloside IV Attenuates High-Glucose-Induced Impairment in Diabetic Nephropathy by Increasing Klotho Expression via the NF-κB/NLRP3 Axis
Published 2023-01-01“…Pyroptosis, an inflammatory form of programmed cell death, is reported to take part in DN pathogenesis recently. …”
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1168
Phosphorus speciation in water and sediments
Published 2025-04-01“…The stream sediments were particularly rich in phosphorus adsorbed on metal oxides, which can be released due to changes in pH. …”
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1169
Piperine as an Herbal Alternative for the Prevention of Drug-Induced Liver Damage Caused by Paracetamol
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Biochemical–molecular–genetic biomarkers in the tear film, aqueous humor, and blood of primary open-angle glaucoma patients
Published 2023-05-01“…Outstanding clinical trials and animal-model study designs, innovative technology, and analytical approaches in bioinformatics are essential tools to successfully uncover novel glaucoma biomarkers with a high potential for translation into clinical practice.MethodsTo better understand the clinical and biochemical-molecular-genetic glaucoma pathogenesis, we conducted an analytical, observational, and case-comparative/control study in 358 primary open-angle glaucoma (POAG) patients and 226 comparative-control individuals (CG) to collect tears, aqueous humor, and blood samples to be processed for identifying POAG biomarkers by exploring several biological pathways, such as inflammation, neurotransmitter/neurotrophin alteration, oxidative stress, gene expression, miRNAs fingerprint and its biological targets, and vascular endothelial dysfunction, Statistics were done by using the IBM SPSS 25.0 program. …”
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Identification of hypoxene metabolites in urine samples using gas chromatography–tandem mass spectrometry for anti-doping control
Published 2024-11-01“…It achieves this by increasing the utilization of oxygen by mitochondria, intensifying oxidative phosphorylation, and as a result, improving tissue respiration. …”
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Hydrogen sulfide protects against cisplatin-induced experimental nephrotoxicity in animal models: a systematic review and meta-analysis
Published 2025-05-01“…Methods According to the pre-registered program (PROSPERO: CRD 42023463779), we searched PubMed/Medline, Embase, and Web of Science databases using the keywords: hydrogen sulfide, cisplatin, acute kidney injury, and alternatives. …”
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Overview of Oncology: Drug-Induced Cardiac Toxicity
Published 2025-04-01“…One particular group of drugs, called anthracyclines, have garnered attention due to their impact on oxidative stress and their ability to cause direct harm to heart muscle cells. …”
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PHARMACOKINETIC PROPERTIES OF A NEW KAPPA-OPIOID ANALGESIC RU-1205 COMPOUND AT A SINGLE PERORAL ADMINISTRATION
Published 2021-07-01“…Biotransformation of a substance probably proceeds mainly with the formation of oxidized forms of the initial molecule by reactions of the first phase of metabolic transformation. …”
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Linoleic acid metabolite 13-Hydroxyoctadecadienoic acid as a biphasic ferroptosis modulator in granulosa cells: multi-omics analysis of ovine atretic follicles
Published 2025-05-01“…Introduction13-Hydroxyoctadecadienoic acid (13(S)-HODE) is a bioactive lipid derived from linoleic acid, it plays prominent roles in cellular processes such as lipid metabolism, oxidative stress, and apoptosis. Follicular atresia is a complex physiological process involving multiple forms of cell death. …”
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Targeting p53-p21 signaling to enhance mesenchymal stem cell regenerative potential
Published 2025-06-01Get full text
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Enhanced superconducting qubit performance through ammonium fluoride etch
Published 2024-01-01Get full text
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Cyclodextrin attenuates atherosclerosis by diminishing gasdermin D (GSDMD)-mediated pyroptosis
Published 2025-07-01“…Abstract Pyroptosis, a programmed form of cell death, typically increases during the atherosclerosis development. …”
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