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Photothermal-electrocatalysis interface for fuel-cell grade ammonia harvesting from the environment
Published 2025-07-01Get full text
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925
Fasting induces the expression of PGC-1α and ERR isoforms in the outer stripe of the outer medulla (OSOM) of the mouse kidney.
Published 2011-01-01“…Taken together, our data suggest that fasting activates the energy balance program in the OSOM of the kidney.…”
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926
Compositional stratigraphy of clay‐bearing layered deposits at Mawrth Vallis, Mars
Published 2008-06-01Get full text
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927
The significance of calcium ions in cerebral ischemia-reperfusion injury: mechanisms and intervention strategies
Published 2025-05-01“…These ions are integral not only for intracellular signaling pathways but also for various pathological processes, such as programmed cell death, inflammatory responses, and oxidative stress. …”
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When HSFs bring the heat—mapping the transcriptional circuitries of HSF-type regulators in Candida albicans
Published 2025-01-01“…I highlight how they can regulate, in common, a crucial developmental program: filamentous growth.…”
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Anticancer Potential of Bioactive Compounds in Premna serratifolia, Premna odorata, and Premna tomentosa: A Review of In Vitro Evidence
Published 2025-05-01“…The compounds identified—such as flavonoids, terpenoids, and steroids—exhibit diverse actions, including cell cycle arrest, apoptosis induction, inhibition of metastasis, oxidative stress modulation, and autophagy. Key compounds like quercetin, kaempferol, and stigmasterol demonstrate multi-targeted actions, effectively regulating pathways such as PI3K/AKT and NF-κB while selectively targeting cancer cells. …”
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Renalase inhibition defends against acute and chronic β cell stress by regulating cell metabolism
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933
Decreased telomerase activity and shortened telomere length in infants whose mothers have gestational diabetes mellitus and increased severity of telomere shortening in male infant...
Published 2024-12-01“…We hypothesize that the poor intrauterine environment in pregnant women with GDM may lead to chromosomal DNA damage and telomere damage in umbilical cord blood cells, providing evidence of an association between intrauterine programming and increased long-term metabolic disease risk in offspring.MethodsWe measured telomere length (TL), serum telomerase (TE) activity, and oxidative stress markers in umbilical cord blood mononuclear cells (CBMCs) from pregnant women with GDM (N=200) and healthy controls (Ctrls) (N=200) and analysed the associations of TL with demographic characteristics, biochemical indicators, and blood glucose levels.ResultsThe length of telomeres in umbilical CBMCs in the GDM group was significantly shorter than that in the Ctrl group (P<0.001), and the shortening of telomeres in male infants in the GDM group was more significant than that in the Ctrl group (P<0.001) after adjustment for Pre-pregnancy body mass index (PBMI), Pregnancy weight gain (PGW), and Triglyceride (TG) as confounding factors. …”
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Ferroptosis as a therapeutic target in glioblastoma: Mechanisms and emerging strategies
Published 2025-09-01“…Ferroptosis is a promising therapeutic avenue for combating drug-resistant cancers because it is a recently discovered mechanism of programmed cell death that oxidizes membrane lipids and is triggered by an accumulation of reactive oxygen species. …”
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MS and GC–MS Analytical Methods for On-Line Thermally Induced Evolved Gas Analysis (OLTI-EGA)
Published 2025-07-01“…Pyrolyzers, thermobalances, or simple heaters can increase the temperature of the analyzed samples according to a programmed and software-managed ramp, allowing for control over both the heating rate and isothermal stages. …”
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Metabolic reprogramming driven by Ant2 deficiency augments T Cell function and anti-tumor immunity in mice
Published 2025-05-01“…Metabolic profiling reveals that these T cells adopt an activated-like metabolic program with increased mitobiogenesis and anabolism. …”
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Siglec‐G Suppresses CD8+ T Cells Responses through Metabolic Rewiring and Can be Targeted to Enhance Tumor Immunotherapy
Published 2024-12-01“…However, their effector function can be severely impaired by inhibitory receptors such as programmed death‐1 (PD‐1) and T cell immunoglobulin domain and mucin domain‐3 (Tim‐3). …”
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ncRNAs-Mediated Pyroptosis in Cerebral Ischemia-Reperfusion Injury: Pathophysiology, Mechanisms, and Therapeutic Perspectives
Published 2025-02-01“…Cerebral ischemia-reperfusion injury (CIRI) is a complex pathological process triggered by transient obstruction of blood flow and subsequent reperfusion, ultimately leading to intracellular disturbances such as oxidative stress, inflammatory responses, and programmed cell death. …”
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Understanding the Growth and Properties of Sputter‐Deposited Phase‐Change Superlattice Films
Published 2025-06-01“…Several reports have highlighted that programming efficiency improves in devices featuring superlattice stacks, such as Ge2Sb2Te5/Sb2Te3. …”
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VDAC1: A Key Player in the Mitochondrial Landscape of Neurodegeneration
Published 2024-12-01“…Mitochondrial dysfunction and oxidative stress are central features of neurodegenerative diseases. …”
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