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681
Different Heat Tolerance of Two Creeping Bentgrass Cultivars Related to Altered Accumulation of Organic Metabolites
Published 2025-06-01“…In addition, the data can also be utilized in breeding programs to improve the heat tolerance of other grass species. …”
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682
Comprehensive Insights into Sarcopenia in Dialysis Patients: Mechanisms, Assessment, and Therapeutic Approaches
Published 2025-03-01“…The pathogenesis involves a complex interplay of chronic inflammation, oxidative stress, metabolic acidosis, hormonal imbalances, protein waste, malnutrition, and reduced physical activity. …”
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683
Electrochemical sensing of 3,3’-Dichlorobiphenyl using green-synthesized gold nanoparticles and Polyvinylpyrrolidone composite
Published 2025-07-01“…The fabricated AuNP-PVP composite, deposited on an indium tin oxide (ITO) electrode, exhibited superior electrochemical activity and sensitivity, attributed to its high surface area and conductivity. …”
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684
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686
Transcriptomic Profiling of Hypoxia-Adaptive Responses in Tibetan Goat Fibroblasts
Published 2025-05-01“…These findings underscore the pivotal role of gene–environment interactions in hypoxic adaptation, offering novel perspectives for both livestock breeding programs and biomedical research initiatives.…”
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687
Assessing cold stress resilience in wild chickpea accessions using physiological, biochemical, and reproductive traits
Published 2025-07-01“…The wild chickpea accessions exhibiting high seed yield under cold stress are promising candidates for breeding programs aimed at cold tolerance.…”
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688
Diagnostic and prognostic value of inflammatory indices in patients with prediabetes and type 2 diabetes mellitus
Published 2025-05-01“…The levels of SII, SIRI, HbA1c, arginase, inducible nitric oxide synthase, and other metabolic markers were measured. …”
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689
Prolonged heat stress in Brassica napus during flowering negatively impacts yield and alters glucosinolate and sugars metabolism
Published 2025-05-01“…DEGs and metabolites identified through this study could serve as important biomarkers for breeding programs to select cultivars with stronger resistance to heat. …”
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690
STIM1‐mediated calcium influx controls antifungal immunity and the metabolic function of non‐pathogenic Th17 cells
Published 2020-07-01“…STIM1 deletion impaired the production of Th17 cytokines essential for antifungal immunity and compromised the expression of genes in several metabolic pathways including Foxo and HIF1α signaling that regulate glycolysis and oxidative phosphorylation (OXPHOS). Our study further revealed distinct roles of STIM1 in regulating transcription and metabolic programs in non‐pathogenic Th17 cells compared to pathogenic, proinflammatory Th17 cells, a finding that may potentially be exploited for the treatment of Th17 cell‐mediated inflammatory diseases.…”
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691
Assessing the Effects of Pesticides on Aquacultured Fish and Ecosystems: A Comprehensive Environmental Health Review
Published 2025-05-01“…This can promote liver dysfunction, metabolism deregulation, oxidative stress, and hematological imbalances, impair immune responses, and adversely affect fish reproduction. …”
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692
Cell biomechanics on muscle atrophy: from intricate mechanisms to therapeutic frontiers
Published 2025-12-01“…Although core molecular pathways and cellular changes are well characterized, the role of mechanical cues in modulating these mechanisms remains underexplored.Main Findings Our review reveals five convergent atrophy drivers—mechanical unloading, ECM alterations, mitochondrial dysfunction/oxidative stress, inflammation, and endocrine imbalance—that converge on inhibited mTORC1 signaling, activated FoxO/UPS/autophagy, and impaired satellite‐cell function. …”
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693
Evaluation of different sesame varieties cultivated under saline conditions in the southwestern coastal region of Bangladesh
Published 2025-02-01“…Sesame (Sesamum indicum L.) is widely used in many cooking techniques worldwide, and it is known as the ''queen of oilseeds'' because it contains polyunsaturated lipids that prevent oxidative rancidity and carry oil content up to 60%. …”
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694
Sex differences in resting skeletal muscle and the acute and long-term response to endurance exercise in individuals with overweight and obesity
Published 2025-08-01“…Both sexes adapted to 8-week endurance training by upregulating mitochondrial proteins involved in TCA cycle, oxidative phosphorylation, and β-oxidation. Training equalized fast-twitch fiber type protein levels, mainly by reducing them in males. …”
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695
Comparative Analysis of Physiological Parameters, Antioxidant Defense, Ion Regulation, and Gene Expression in Two Distinct Maize Hybrids Under Salt Stress at Seedling Stage
Published 2025-04-01“…These insights are highly valuable for breeding programs focused on developing salt-tolerant maize hybrids.…”
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696
Cardiotoxicity of Chemotherapeutic Drugs (Literature Review and Clinical Case Description)
Published 2019-12-01“…The most common pathophysiological mechanism of anthracycline cardiotoxicity is described by the oxidative stress hypothesis, which implies that the generation of reactive oxygen species and lipid peroxidation of the cell membrane damages cardiomyocytes. …”
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697
Heterozygous Kmt2d loss diminishes enhancers to render medulloblastoma cells vulnerable to combinatory inhibition of LSD1 and OXPHOS
Published 2025-05-01“…Here, we show that heterozygous Kmt2d loss in murine cerebellar regions promotes MB genesis driven by heterozygous loss of the MB-suppressor gene Ptch via the upregulation of tumor-promoting programs (e.g., oxidative phosphorylation [OXPHOS]). …”
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698
Shared transcriptional regulators and network rewiring identify therapeutic targets linking type 2 diabetes mellitus and hypertension
Published 2025-08-01“…This study aimed to uncover shared transcriptional programs and disease-specific regulatory networks contributing to cardiometabolic dysfunction.MethodsWe systematically selected transcriptomic datasets and employed an integrative systems biology approach that combined differential gene expression analysis, co-expression network construction, protein-protein interaction mapping, transcription factor activity inference, and network rewiring analysis. …”
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699
Seed priming with salicylic acid enhances salt stress tolerance by boosting antioxidant defense in Phaseolus vulgaris genotypes
Published 2025-04-01“…SA pretreatment also significantly enhanced the antioxidant defense system, reducing oxidative damage induced by salinity stress. Principal component analysis (PCA) successfully categorized the genotypes into semi-tolerant, tolerant, semi-sensitive, and sensitive classes based on their stress responses. …”
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700
Observational study of ground-level ozone and climatic factors in Craiova, Romania, based on one-year high-resolution data
Published 2024-11-01“…Using two statistical analysis programs, Python and SPSS, a good understanding of the correlations between these variables and ozone concentration is obtained. …”
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