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Development of a multi-epitope vaccine from outer membrane proteins and identification of novel drug targets against Francisella tularensis: an In Silico approach
Published 2025-04-01“…Outer membrane proteins (OMPs) were predicted using subcellular localization tools and immunogenicity was evaluated using a reverse vaccinology pipeline. …”
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Separation and Characterization of Heterogeneity Among Various Sizes of Outer Membrane Vesicles Derived from the Probiotic <i>Escherichia coli</i> Nissle 1917
Published 2025-05-01“…Outer membrane vesicles (OMVs) are extracellular vesicles secreted by Gram-negative bacteria with diameters of 20–250 nm. …”
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Axial Compressive Behavior of Outer Square Inner Circular Spontaneous Combustion Coal Gangue Concrete-Filled Double-Skin Steel Tubular Stub Column
Published 2024-12-01“…The analysis encompasses parameters such as the strength of the core SCGCAC (<i>f</i><sub>c,i</sub>), the strength of the sandwiched concrete (<i>f</i><sub>c,o</sub>), the yield strength of the outer steel tube (<i>f</i><sub>y,o</sub>), the yield strength of the inner steel tube (<i>f</i><sub>y,i</sub>), the width-to-thickness ratio (<i>B</i>/<i>t</i><sub>o</sub>), the diameter-to-thickness ratio of the inner tube (<i>D</i>/<i>t</i><sub>i</sub>), and the diameter-to-width ratio of the outer tube (<i>D</i>/<i>B</i>). …”
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The Three Ni Doctrine of Healing the World: A New Breakthrough in Qing Dynasty Daoism’s Interpretation of the “Inner Sage, Outer King” Ideal Within the Three Teachings Unity Moveme...
Published 2025-05-01“…It marks a significant breakthrough in the traditional Chinese ideal of “Inner Sage, Outer King” 內聖外王. Furthermore, Min integrated the Three Ni Doctrine with the Celestial Immortality teachings of Jing’ai Mountain Daoism, creating a systematic Daoist orthodoxy known as the “Heart Lineage of the Most High” (Ch. …”
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The Legal Regime of Natural Resources of Celestial Bodies: Current State of the Relevant Russian Laws and Perspectives for a Common BRICS Legal Approach
Published 2025-08-01“…In view of the current global outer space-related transformation processes, the legal regime concerning the natural resources of celestial bodies has become one of the most challenging issues to coherently resolve at international and, accordingly, national legal levels. …”
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Opportunities and challenges of bacterial extracellular vesicles in regenerative medicine
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Bacterial membrane-modified cerium oxide nanoboosters enhance systemic antitumor effects of radiotherapy in metastatic triple-negative breast cancer
Published 2025-02-01“…Abstract Background Radiotherapy plays an important role in the treatment of triple-negative breast cancer, yet its ability to trigger systemic responses against distant tumors remains limited. Results To address this challenge, we developed a biomimetic nanobooster by incorporating cerium oxide (CeO2) nanoparticles with bacterial outer membrane vesicles (OMVs), termed CeO2@OMV. …”
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Scheduling of Mixed Fleet Passing Through River Bottleneck in Multiple Ways
Published 2024-10-01“…To handle the nonlinear terms in the model, an outer approximation technique is applied to linearize the model while ensuring the approximation error remains controlled. …”
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The contextual adaptation and educational impacts of the mhGAP-IG to address child mental and behavioral disorder treatment gap in China: A mixed-method study
Published 2025-06-01“…Barriers were concentrated in intervention characteristics (e.g., complexity, time and labor costs) and outer setting (e.g., stigma, high treatment cost). …”
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Rapid inspection for shaft parts in the automotive field
Published 2025-05-01“…It is equipped with key mechanical structures, including a positive and negative detection and total length measurement component, an outer diameter detection component, and an outer diameter detection and dual-flank meshing cross-bar distance measurement component. …”
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Targeting copper homeostasis: Akkermansia-derived OMVs co-deliver Atox1 siRNA and elesclomol for cancer therapy
Published 2025-05-01“…However, the therapeutic efficacy of copper ionophores such as elesclomol (ES) is often hindered by cellular copper homeostasis mechanisms that limit copper influx and cuproptosis induction. To address this challenge, we developed a nanoagent utilizing outer membrane vesicle (OMV) derived from Akkermansia muciniphila (Akk) for co-delivery of antioxidant 1 copper chaperone (Atox1)-targeting siRNA and ES (siAtox1/ES@OMV) to tumors. …”
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Crosstalk between polymorphic toxin-immunity systems involved in kin discrimination
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Addressing the impact of Lyman opacity in inference of divertor plasma conditions with 2D spectroscopic camera analysis of Balmer emission during detachment in JET L-mode plasmas
Published 2025-03-01“…The impact of re-absorption of the deuterium Lyman series emission was addressed in inferring divertor plasma conditions from Balmer series emission with 2D spectroscopic camera analysis during detachment in JET L-mode plasmas. …”
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School-Based Health Centers Addressing Health Equity for LGBTQ + Patients (SBHCs HELP): protocol for a stepped-wedge trial to implement innovations promoting structural competency...
Published 2024-11-01“…Discussion This study addresses the long-term goal of high-quality care and decreased health disparities for SGD youth. …”
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Evaluation of Immunogenicity of an Orf Virus Vector-Based Vaccine Delivery Platform in Sheep
Published 2025-06-01“…It is well-established for chlamydial infections, including ovine enzootic abortion, that the major outer membrane protein (MOMP) antigen is protective. …”
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Physico-Mechanical Properties of Male and Female Hemp Plants
Published 2025-04-01“…The results showed that male hemp plants have an increase in thickness and inner and outer diameter values from the lower to the upper region compared to female hemp plants. …”
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Effect of double-layer formwork curing on the early temperature field and properties of precast concrete components in environments with large diurnal temperature variations
Published 2024-12-01“…Abstract An efficient double-layer formwork curing method using an “inner supporting formwork + outer insulation formwork” was proposed in this study to address the early cracking of precast concrete components in high altitude regions. …”
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A NeutroEconomic Resilience Framework for High-Quality Regional Economic Development Under the New Normal
Published 2025-07-01“…The findings underscore NeutroAlgebra's potential in addressing complex economic challenges. …”
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