Relevance, ad hoc concepts and analogy by Ewa Mioduszewska

“… In Relevance Theory (RT) concepts are “enduring elementary mental structure[s] capable of playing different discriminatory or inferential roles on different occasions in an individual’s mental life.” …”
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Investigating Non-steroidal Anti-Inflammatory Drugs as Potential Cancer Adjuncts: A Novel Approach to Cancer Therapy by Sadaf Alam, Leena Anjum, Muhammad Haneef

“…Methodology: A comprehensive review of clinical, epidemiological, and experimental studies was conducted to assess the roles of NSAIDs including aspirin, meloxicam, celecoxib, sulindac, naproxen, indomethacin, and piroxicam, in cancer treatment. …”
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Des chiens pour protéger contre les loups des brebis en parcs clôturés : une pratique nouvelle et encore problématique by Baptiste Potet, Charles-Henri Moulin, Michel Meuret

“…Within their group, the guard dogs can play complementary roles and this optimizes protection. The rearrangement of dog groups during the year can cause difficulties. …”
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Preliminary investigation of the effect of ferulic acid on miRNAs and LncRNAs in Mongolian horse skeletal muscle satellite cells by Wendian Gong, Wenqi Ding, Tugeqin Bou, Lin Shi, Yanan Lin, Xiaoyuan Shi, Zheng Li, Huize Wu, Manglai Dugarjaviin, Dongyi Bai

“…The target genes of non-coding RNAs are enriched in processes such as positive regulation of TOR signaling, cell migration, and positive regulation of vascular endothelial cell proliferation, where they play important roles in cell growth and proliferation. Dual luciferase reporter assays confirmed that LncRNA MSTRG.7632.14 competitively binds to eca-miR-6529, thereby relieving its inhibitory effect on PDK1 and forming a biologically functional regulatory axis.ConclusionThis study reveals that ferulic acid can regulate muscle fiber proliferation and type transformation through the interaction network of non-coding RNAs and target genes, providing potential targets for optimizing the athletic performance and muscle function of equids.…”
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Molecular imprinting and nanomaterial synergy for lactate detection by Christopher Animashaun, Gymama Slaughter

“…Key fabrication strategies, such as electropolymerization, green nanomaterial synthesis, and surface imprinting, are critically examined for their roles in optimizing imprinting sensitivity and electron transfer efficiency. …”
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<i>In Vitro</i> Assessment of Biological and Functional Properties of Potential Probiotic Strains Isolated from Commercial and Dairy Sources by Elmira Kelidkazeran, Meriam Bouri Yildiz, Fikrettin Sahin

“…The findings indicate that these probiotic strains exhibit diverse functionalities beyond intestinal health, with potential roles in digestion, oxidative stress reduction, and immune support. …”
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Comparative genome analysis of Campylobacter fetus subspecies revealed horizontally acquired genetic elements important for virulence and niche specificity. by Sabine Kienesberger, Hanna Sprenger, Stella Wolfgruber, Bettina Halwachs, Gerhard G Thallinger, Guillermo I Perez-Perez, Martin J Blaser, Ellen L Zechner, Gregor Gorkiewicz

“…It further highlights the importance of surface-exposed structures to C. fetus pathogenicity and demonstrates how evolutionary forces optimize the fitness and host-adaptation of these pathogens.…”
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Harnessing Nitrous Oxide for Sustainable Methane Activation: A Computational Exploration of CNC-Ligated Iron Catalysts by Bruce M. Prince

“…The triplet (S = 1) and quintet (S = 2) spin states exhibit critical roles in the catalytic pathway, with intersystem crossing facilitating optimal reactivity. …”
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Legal Protection for Malnourished Children for Fulfillment of Health Services by Amelia Pranita Ikhsan, Hasbir Paserangi, Muh Hasrul

“…The results of the study found that the legal protection for malnourished children for the fulfillment of health services in the prevention of malnutrition in children who were not carried out optimally. Various cross-sectoral roles are needed in the effort to fulfill the rights of malnourished children. …”
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Bedaquiline and linezolid regimens for multidrug-resistant tuberculosis: a systematic review and meta-analysis by Mahdis Cheraghi, Mehrnaz Amiri, Sahar Andarzgoo, Fatemeh Zarei, Zahra Sadat Seghatoleslami, Rosella Centis, Dina Visca, Lia D’Ambrosio, Emanuele Pontali, Mohammad Javad Nasiri, Giovanni Battista Migliori

“…This systematic review and meta-analysis sought to examine the efficacy of linezolid (LZD) and bedaquiline (BDQ) in MDR-TB treatment regimens, evaluating their roles in enhancing therapeutic success and informing optimized management of MDR-TB. …”
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Appropriate dietary phosphorus levels promote growth performance, mineral retention, and hepatic lipid metabolism in juvenile American eels (Anguilla rostrata) by Yichuang Xu, Shuo Wang, Xinyu Hu, Pan Wang, Xiaozhao Han, Jinyue Yang, Ying Liang, Shaowei Zhai

“…Phosphorus (Pi) is an essential mineral for fish and exerts critical roles in growth, metabolism, and skeletal development. …”
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Getting time and building trust: unveiling the systemic, relational, and personal factors influencing clinical pharmacy service implementation in South Africa, a qualitative study by Lucille Crafford, Rashmi A Kusurkar, Elmien Bronkhorst, Andries Gous, Anouk Wouters

“…A lack of dedicated positions and healthcare professionals’ misunderstanding restrict ward activities and hinder full collaboration, limiting their potential to optimize patient care. This study addresses a gap by exploring how perceived healthcare professionals’ understanding of clinical pharmacists’ roles impacts their motivation and service implementation. …”
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Spatio-Temporal Influencing Factors of the Coupling Coordination Degree Between China’s New-Type Urbanization and Transportation Carbon Emission Efficiency by Han Jia, Weidong Li, Runlin Tian

“…The following is found: (1) NU and CET show a spatial pattern of “leading in the east and lagging in the west”, and are optimized over time, but with significant regional differences; (2) the degree of coupling coordination jumps from “basic disorder” to “basic coordination”, but has not yet reached the level of advanced coordination, with significant spatial clustering characteristics (Moran’s I index between 0.244 and 0.461); (3) labor force structure, transportation and energy intensity, industrial structure and scientific and technological innovation are the core factors driving the coupled coordination, and have significant spatial spillover effects, while government intervention and per capita income have limited roles. …”
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Reproductive cycle of cultured chub mackerel (Scomber japonicus), in a land-based tank system in Jeju Island, Korea by Seong Il Baek, Seung Cheol Ji, Jeong-Hyeon Cho, Jeong-Hyeon Cho

“…Thus, identifying reproductive patterns of chub mackerel in land-based systems is essential to optimize breeding strategies and juvenile production. …”
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Efficacy and safety of immunotherapy or antiangiogenic agent-based treatment strategies versus chemotherapy as first-line treatment for extensive-stage small cell lung cancer: a ne... by Chengjun Wang, Chuang Yang, Wen Zhao, Rongyu Zhang, Tiantian Xuan, Jisheng Li

“…These findings clarified the roles of ICIs and antiangiogenic agent-based treatment strategies in this population.…”
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Unveiling the determinants of battery electric vehicle performance: A systematic review and meta-analysis by Fangjie Liu, Muhammad Shafique, Xiaowei Luo

“…The findings highlight that although technological advancements and regulatory frameworks are the predominant drivers of BEV performance, environmental conditions and user behaviors also play significant roles. The key emerging topics identified suggest further research avenues, particularly in optimizing battery technology and expanding policy support. …”
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Improved Production of Recombinant Human Activin A in Escherichia coli by Zahra Hajihassan, Navid Nazari, Fatemeh Armaghan

“…Activin A is a member of transforming growth factor β (TGF-β) superfamily. It plays numerous roles in the body such as cell growth regulation and differentiation, wound repairing and modulation of inflammatory responses. …”
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Advances in Flow Control Methods for Pump-Stall Suppression: Passive and Active Approaches by Hongbo Zhao, Xiangkai Zhou, Long Meng, Xuejin Zhu, Chengqi Mou, Peijian Zhou

“…The discussion highlights passive and active flow control methods, emphasizing their roles in suppressing stall phenomena. Passive flow-control strategies, including surface roughness, grooves, obstacles, fixed guide vanes, and vortex generators, are examined with a focus on their mechanisms and effectiveness in suppressing stall. …”
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Physicochemical and Functional Properties of Soluble and Insoluble Dietary Fibers in Whole Grains and Their Health Benefits by Pathumi Ariyarathna, Patryk Mizera, Jarosław Walkowiak, Krzysztof Dziedzic

“…Future research should focus on enhancing the bioavailability and functionality of whole-grain dietary fibers, optimizing the methods by which they are extracted, and exploring their potential applications in the food and pharmaceutical industries.…”
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Individually Modified Microneedle Array for Minimal Invasive Multi-Electrolyte Monitoring by Ketian Yu, Yukun Ma, Yiming Wei, Wanying Chen, Zhen Dai, Yu Cai, Xuesong Ye, Bo Liang

“…Electrolytes play crucial roles in regulating nerve and muscle functions. Currently, microneedle technology enables real-time electrolyte monitoring through minimally invasive methods. …”
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