Exploring salinity adaptation in teleost fish, focusing on omics perspectives on osmoregulation and gut microbiota by Evodia Moses Mkulo, Evodia Moses Mkulo, Evodia Moses Mkulo, Lukman Iddrisu, Mpwaga Alatwinusa Yohana, Anna Zheng, Anna Zheng, Anna Zheng, Jiahao Zhong, Jiahao Zhong, Jiahao Zhong, Minxuan Jin, Minxuan Jin, Minxuan Jin, Felix Danso, Linjuan Wang, Linjuan Wang, Linjuan Wang, Huijuan Zhang, Huijuan Zhang, Huijuan Zhang, Baogui Tang, Baogui Tang, Baogui Tang, Hui Zhou, Hui Zhou, Hui Zhou, Kwaku Amoah, Kwaku Amoah, Kwaku Amoah, Jiansheng Huang, Jiansheng Huang, Jiansheng Huang, Bei Wang, Bei Wang, Bei Wang, Zhongliang Wang, Zhongliang Wang, Zhongliang Wang, Zhongliang Wang

“…Although some species tolerate varying salinity levels, rapid shifts beyond their optimal tolerance cause stress. Euryhaline species experience stress at extreme salinities, whereas stenohaline species are sensitive to minor changes. …”
Get full text

Association of weight-adjusted waist index with preserved ratio impaired spirometry and all-cause mortality by Xin Jiao, Xin Jiao, Xin Jiao, Linqi Huang, Luoqi Lin, Luoqi Lin, Luoqi Lin, Fanggang Zhu, Fanggang Zhu, Fanggang Zhu, Feiting Fan, Feiting Fan, Feiting Fan, Jingmin Xiao, Jingmin Xiao, Jingmin Xiao, Lei Wu, Lei Wu, Lei Wu, Lin Lin, Lin Lin, Lin Lin, Yuanbin Chen, Yuanbin Chen, Yuanbin Chen

“…A U-shaped curve characterized the nonlinear WWI-mortality association in PRISm (p for nonlinearity = 0.0025), whereas positive linear trends were observed in non-PRISm individuals and overall.ConclusionLower WWI levels were linked to an elevated PRISm risk, highlighting central obesity’s role in respiratory health. Maintaining an optimal WWI may mitigate mortality risk in adults with PRISm, emphasizing the need for targeted weight management.…”
Get full text

Navigating disruption in the PID landscape: embracing opportunities and anticipating threats in the next ten years by Lúcia Mamede, Roser Cantenys Sabà, Roser Cantenys Sabà, Samya Van Coillie, Johan Prévot, Silvia Sánchez-Ramón, Cecilia Poli, Cecilia Poli, Cecilia Poli, Anne Barasa, Björn W. Schuller, Björn W. Schuller, Björn W. Schuller, Ayal Hendel, Nicolas Garcelon, Cornelis Boersma, Cornelis Boersma, Cornelis Boersma, Pamela Lee, Claire Booth, Claire Booth, Luigi D. Notarangelo, Jose Drabwell, Nicholas L. Rider, Frank J. T. Staal, Frank J. T. Staal, Siobhan O. Burns, Siobhan O. Burns, Martin Van Hagen, Martin Van Hagen, Martin Van Hagen, Martine Pergent, Jacques G. Rivière, Jacques G. Rivière, Jacques G. Rivière, Jacques G. Rivière, Nizar Mahlaoui, Nizar Mahlaoui, Nizar Mahlaoui

“…IntroductionThe International Patient Organisation for Primary Immunodeficiencies (IPOPI) held its third edition of the Global Multi-Stakeholders’ Summit, gathering key primary immunodeficiencies (PID) stakeholders and experts to discuss and foment global collaboration.MethodsThis edition focused on the impact of genomic medicine in PID treatment, the role of digital health, including artificial intelligence, in PID care, and how to anticipate and minimise risks to ensure optimal patient access to care.ResultsThese discussions aimed to examine current hurdles and brainstorm feasible solutions and priorities for the PID community in these areas in the next ten years.DiscussionThese discussions led to recommendations for comprehensive approaches to care and access to treatment for PID patients, suggesting actions that will bring the community closer to treatments based on real-world evidence and adjusted to patient’s needs. …”
Get full text

A novel risk stratification system for primary small-cell carcinoma of the esophagus: indication for prognostication and staging by Yong Yang, Jing Yu, Silin Chen, Xiaomin Wang, Furong Wu, Cheng Huang, Yuping Lin, Tianlan Tang, Tiantian Gao, Zewei Zhang, Yiping Zhang, Liyan Wang, Junqiang Chen, Zhenyang Zhang, Weijie Wang, Jiangbo Lin, Ying Wang, Yuanji Xu, Lei Zhao

“…The current study was to investigate the role of a novel risk stratification system (RSS) for PSCCE. …”
Get full text

Adjuvant combination and antigen multimerization shape neutralizing antibody and T cell responses to a SARS-CoV-2 RBD subunit vaccine by João Pedro da Silva Nunes, Mariângela de Oliveira Silva, Juliana de Souza Apostolico, Isabela Pazotti Daher, Rodolfo Ferreira Marques, Marcio Massao Yamamoto, Alexia Adrianne Venceslau Brito Carvalho, Maria Fernanda de Castro-Amarante, Edison Luiz Durigon, Carsten Wrenger, Luiz Mario Ramos Janini, Edmarcia Elisa de Souza, Robert Andreata-Santos, Juliana Terzi Maricato, Edecio Cunha-Neto, Edecio Cunha-Neto, Edecio Cunha-Neto, Jorge Kalil, Jorge Kalil, Silvia Beatriz Boscardin, Silvia Beatriz Boscardin, Daniela Santoro Rosa, Daniela Santoro Rosa

“…Despite the use of distinct platforms, most approved vaccines utilize the Spike protein as the main antigen due to its pivotal role in virus entry, mediated by the receptor binding domain (RBD). …”
Get full text

Patient-reported outcomes (PROs) in clinical trials and in clinical practice: report from the XXI national conference of the Italian Association of Medical Oncology (AIOM) by Oriana Ciani, Carla Ida Ripamonti, Fabio Efficace, Giuseppe Viscardi, Francesco De Lorenzo, Massimo Di Maio, Lara Gitto, Elisabetta Iannelli, Francesco Perrone, Ethan Basch, Alessandra Raimondi, Antonella Brunello, Carmine Pinto, Alberto Puccini, Silvana Quaglini, Evaristo Maiello, Martina Pagliuca, Saverio Cinieri, Gianmauro Numico, Paolo Bossi, Patrizia Popoli, Tiziana Latiano, Laura Marandino, Francesco Longo, Alberto Servetto, Angela Piattelli, Giordano Domenico Beretta, Davide Petruzzelli, Marco Zibellini, Laura Locati, Gualberto Gussoni, Gianluca Mignone, Pricivel M Carrera

“…Addressing infrastructural and technological challenges will be vital for optimising patient outcomes and ensuring optimal care across the cancer journey.…”
Get full text

Development of a single-cell cloning technique for isolation of Pentatrichomonas hominis: a promising tool for diagnosing Trichomonas spp. infections in the pig breeding industry by Yibin Zhu, Haiming Cai, Shenquan Liao, Juan Li, Siyun Fang, Hanqin Shen, Dingai Wang, Zhuanqiang Yan, Minna Lv, Xuhui Lin, Junjing Hu, Yongle Song, Xiangjie Chen, Lijun Yin, Jianfei Zhang, Nanshan Qi, Mingfei Sun

“…Abstract Background Pig breeding is a crucial sector of the global economy, playing a significant role in meat production. However, the prevalence of Trichomonas spp., a group of parasites known to induce diarrhea in various hosts, presents significant challenges in breeding facilities. …”
Get full text

An urgent call for more ambitious ocean literacy strategies in marine protected areas: a collaboration project with small-scale fishers as a case study by Janire Salazar, Janire Salazar, Sílvia Gómez, Begoña Vendrell-Simón, Begoña Vendrell-Simón, Begoña Vendrell-Simón, Miroslav Pulgar, Núria Viladrich, Núria Viladrich, Núria Viladrich, Stefano Ambroso, Stefano Ambroso, Stefano Ambroso, Patricia Baena, Andreu Santín, Andreu Santín, Maria Montseny, Maria Montseny, Marina Biel-Cabanelas, Josep-Maria Gili

“…Cold-Water Corals play a paramount role in marine benthic ecosystems, increasing their complexity and providing spawning and nursery habitats to many species. …”
Get full text

2025 photonics for agrifood roadmap: towards a sustainable and healthier planet by Lien Smeesters, Francesca Venturini, Stefan Paulus, Anne-Katrin Mahlein, David Perpetuini, Daniela Cardone, Arcangelo Merla, Benjamin Gac, Stephane Perrin, Denis Trégoat, Luiz Poffo, Antoine Fournier, Giuseppe Bonifazi, Silvia Serranti, Wenzhi Liao, Noureddin Osseiran, Mathias Vanwolleghem, Romain Peretti, Aparajita Bandyopadhyay, Karl Bertling, Krishnan Parameswaran, Aleksandar D Rákic, Amartya Sengupta, Sune Svanberg, Małgorzata Kujawinska, Daniel Cozzolino, Dolores Pérez Marín, José A Entrenas de León, Irina Torres Rodríguez, Marietta Fodor, Eszter Benes, Anna Matkovits, Zsuzsa Jókai, Simona M Cristescu, Amir Khodabakhsh, Khalil Jahromi, Mohammadreza Nematollahi, Frans H Harren, Eugene Rokx, Ewa Sikorska, Kay Sowoidnich, Martin Maiwald, Bernd Sumpf, Matthieu Roussey, Kai-Erik Peiponen, Antoni Femenias, Polina Fomina, Vjekoslav Kokoric, Robert Stach, Boris Mizaikoff, Maria Konstantaki, Stavros Pissadakis, Umberto Michelucci, Sławomir Paśko, Anna Pakuła, Richard A Crocombe, Ellen V Miseo, Andreas C Liapis, Faisal Ahmed, Zhipei Sun, Chrysoula Chandrinou, Marianneza Chatzipetrou, Ioanna Zergioti, Ulrich Trog, Anja Haase, Martin Smolka, Lex Oosterveld, Chris Van Hoof, André Müller, Michael Hlavatsch, Diellza Bajrami, Ernesto Olvera-Gonzalez, Nivia Escalante-Garcia, Arturo B Soro, Koenraad Van Hoorde, Brijesh K Tiwari, Thomas Westerhoff, Michael Kneissl, Anna Grazia Mignani

“…Photonics technologies play a crucial role in driving technological advancements within the agrifood industry, aiming to deliver a sustainable food and agriculture, and offering healthy, nutritious and safe food for all of us. …”
Get full text

Effective cellular and neutralizing immunity against SARS-CoV-2 after mRNA booster vaccination is associated with pDC and B cell activation by Dorit Fabricius, Carolin Ludwig, Carolin Ludwig, Matthias Proffen, Matthias Proffen, Janina Hägele, Janina Hägele, Judith Scholz, Judith Scholz, Christiane Vieweg, Christiane Vieweg, Immanuel Rode, Immanuel Rode, Simone Hoffmann, Simone Hoffmann, Sixten Körper, Sixten Körper, Hubert Schrezenmeier, Hubert Schrezenmeier, Bernd Jahrsdörfer, Bernd Jahrsdörfer

“…Despite differences in humoral responses between regimens, breakthrough infection rates up to 25 weeks post-booster were comparable across cohorts, suggesting compensatory mechanisms via cellular immunity.DiscussionOur findings highlight the pivotal role of pDCs and T cells in sustaining effective immunity following mRNA booster vaccination. …”
Get full text

Distinct features of humoral and cellular immunity against Omicron breakthrough infection among chronic liver disease patients: An experience from a follow-up cohort by Yongmei Liu, Yuzhu Shi, Haoting Zhan, Yuling Wang, Wenfang Yuan, Yuchen Xie, Linlin Cheng, Xinru Guo, Xiaomeng Li, Haiyan Kang, Haolong Li, Yongliang Chen, Xingli Sun, Huixia Gao, Fumin Feng, Erhei Dai, Yongzhe Li

“…The positive correlations between humoral/cellular immunity and memory/activated T cells reveal their coordinated role in adaptive immune defense against SARS-CoV-2. …”
Get full text

Mixed-methods, descriptive and observational cohort study examining feeding and growth patterns among low birthweight infants in India, Malawi and Tanzania: the LIFE study protocol by Christopher R Sudfeld, Karim Manji, Rodrick Kisenge, Tisungane Mvalo, Melda Phiri, Christopher Duggan, Lauren Spigel, Anne CC Lee, Bethany A Caruso, Laura Subramanian, Megan Marx Delaney, Shivaprasad S Goudar, Linda Vesel, Katherine EA Semrau, Irving F Hoffman, Melissa Young, Friday Saidi, Jnanindra Nath Behera, Roopa M Bellad, Leena Das, Sangappa Dhaded, Gowdar Guruprasad, Sujata Misra, Sanghamitra Panda, Latha G Shamanur, Sunil S Vernekar, Sarah Somji, Linda Adair, Kiersten Israel-Ballard, Stephanie L Martin, Kimberly L Mansen, Krysten North, Emily Benotti, Eliza Fishman, Katelyn Fleming, Natalie Henrich, Kate Miller, Danielle E Tuller

“…Feeding promotion tailored to meet the nutritional needs of LBW infants in LMICs may serve a crucial role in curbing newborn mortality rates and promoting growth. …”
Get full text

Non-technical skills for neurosurgeons: An international survey by S.M. Cavallo, E. Pellencin, G. Carone, N. Castelli, R. Ayadi, A. Moiyadi, L. Padayachy, T.R. Meling, F. Di Meco, A. Perin, F. Olldashi, A. Al Anazi, I. Kanaan, F. Garcia Colmena, P. Ajler, M. Socolovsky, E. Knosp, C. Raftopoulos, J.C. Rodrigues, Jr., Y.P. Enchev, B. Xu, P. Chul-Kee, K. Rotim, J. Posti, B. Meyer, H. Shimamoto, Y. Makhambetov, J. Frosen, S.P. Chandra, P. Cappabianca, G. Piatelli, L. Genitori, A. Germanò, G. Sabatino, C. Bernucci, C. Giussani, A. Olivi, D. Locatelli, R. Stefini, C. Castrioto, A. Mangiola, M.M. Fontanella, L. Tacconi, C. Conti, M. Skrap, N. El Abbadi, M.R. Sharma, M.S. Shamim, S. Sharif, J.P. Farias, I.S. Florian, A.O. Gushcha, L. Rasulic, P. Vulekovic, B.T. Ang, A. Lagares, R. Diez Valle, J. Ensenat, L. Ley Urzaiz, J.A. Barcia Albacar, S.S. Kupanur, L. Regli, I.F. Dunn, D. Adelson, J. Bederson, A.D. Levi, A.Y. Alturky, C. Matula, B. Cortes, W. Xiang, T. Li, N.M.F. El-Ghandour, R. Kanai, R. Patir, B.K. Misra, S. Dwarakanath, F. Servadei, F. Tomasello, C. Casali, G. Unsgard, J.J. Morcos, T. Souhil, I. Khoja, I. Kehayov, M. Vukic, M. Ziebell, H.A. Gulisano, M. Tange, K. Kurozumi, M. Locatelli, D. Garbossa, J.L. Gomez Amador, A.O. Rodriguez, K. Ashkan, M. Lim, M. Maleki, A. Agrawal, A. Naik, D.M. Sciubba, L.J. Kim, R.J. Spinner, P. McDonald, G. Pavesi

“…Research question: This study seeks to understand how important NTSs are perceived by neurosurgeons across diverse roles and socio-economic backgrounds. The objective is to identify key NTSs and explore their role in surgical precision, teamwork, and collaboration. …”
Get full text

Compartmentalization of High Infratemporal Fossa in Oral Cavity Squamous Cell Carcinomas and Its Impact on Clinical Outcome by Abhishek Mahajan, Ujjwal Agarwal, Renuka M. Ashtekar, Nivedita Chakrabarty, Richa Vaish, Vijay Maruti Patil, Vanita Noronha, Nandini Menon, Vasundhara Smriti, Jai Prakash Agarwal, Sarbani Ghosh-Laskar, Anil K. D’Cruz, Pankaj Chaturvedi, Prathamesh Pai, Asawari Patil, Munita Bal, Swapnil Rane, Neha Mittal, Kumar Prabhash

“…Conclusions: Baseline imaging plays a critical role in guiding individualized treatment and predicting clinical outcomes. …”
Get full text

Influence of Emergent Vegetation Layout on Flow Pattern in a Rectangular Shallow Basin by Junnan LYU, Yuxuan JIANG, Zhidong YAO, Chen YE, Xufeng YAN

“…Objective Shallow basins, varying in natural and artificial forms, are prevalent in urban and rural areas. They play critical roles in ecology, water resource management, environmental protection, and enhancing landscape aesthetics. …”
Get full text

Political Order and Nomadic Life in Iran: From the Afsharid Period to the End of the Qajar Dynasty by Shahram Gholami, Siavash Gholipour

“…Additionally, nomadic practices often misaligned with the optimal productivity of water and soil resources. …”
Get full text

Research Progress on Ambient Visual Information Analysis and Perception Measurement Methods for Motion Vision by Haipeng ZHU, Yuhang KONG, (JPN) OHNO Ryuzo

“…Visual information, continuously changing during movement, plays a critical role in spatial cognition and environmental experience. …”
Get full text

Evaluation Indicators of Science, Technology, and Innovation: A Comparative Study of Iran, Australia, and New Zealand by Leila Namdarian

“…For policymakers, the study offers a roadmap to foster dynamic innovation ecosystems, optimize resource allocation, and enhance global competitiveness. …”
Get full text

Investigating the hatchability and nauplii biometry of Artemia franciscana in unconventional waters of Sistan region, Southeast Iran by Hashem Khandan Barani, Abdolali Rahdari, Narjes Sanchooli, Ali Khosravanizadeh

“…Using these water sources for aquaculture is suggested for optimal utilization and reduction of their adverse effects on the environment. …”
Get full text

Aquatic Environment and Nitrogen and Phosphorus Balance in Micropterus salmoides Culture Under Biofloc Model by Yuqin JIN, Shunlong MENG, Huimin XU, Chao SONG, Limin FAN, Liping QIU, Dandan LI

“…In this regard, aquaculture may play a key role in maximizing the use of various aquatic resources to produce a wide range of food organisms using a combination of intensive farming practices. …”
Get full text