Characterization of the complete chloroplast genome and comparative analysis of the phylogeny and codon usage bias of three Yunnan wild rice species by Rongxin Li, Rongxin Li, Rongxin Li, Bo Wang, Bo Wang, Suqin Xiao, Suqin Xiao, Ling Chen, Ling Chen, Fuyou Yin, Fuyou Yin, Jinlu Li, Jinlu Li, Cong Jiang, Cong Jiang, Dunyu Zhang, Dunyu Zhang, Qiaofang Zhong, Qiaofang Zhong, Yun Zhang, Yun Zhang, Jiaxin Xing, Jiaxin Xing, Zaiquan Cheng, Zaiquan Cheng, Li Liu, Li Liu

“…Fourteen optimal codons were identified, with 13 ending in A/U and one ending in C. …”
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Mitochondrial DNA oxidation and content in different metabolic phenotypes of women with polycystic ovary syndrome by Mailén Rojo, Mailén Rojo, Hernán Pérez, Hernán Pérez, Andrea Liliana Millán, Andrea Liliana Millán, María Constanza Pautasso, Alejandra Duarte, Alejandra Duarte, Giselle Adriana Abruzzese, Alicia Beatriz Motta, Alicia Beatriz Motta, Gustavo Daniel Frechtel, Gustavo Daniel Frechtel, Gustavo Daniel Frechtel, Gloria Edith Cerrone, Gloria Edith Cerrone

“…Mitochondrial dysfunction, characterized by oxidative stress and reduced antioxidant capacity, plays a key role in PCOS pathology.MethodsIn our study, we investigated 81 women with PCOS, and 57 control women aged 16 to 46 years old. …”
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Multi-omics analysis uncovers predictive biomarkers for the efficacy and outcomes of chemoimmunotherapy in advanced unresectable biliary tract cancers by Jiaojiao Ni, Chaoqun Li, Xiaoqing Xu, Qi Xu, Qian Yin, Hanlin Chen, Shurui Zhou, Jingjing Li, Qinhong Zheng, Yanru Xie, Hongjun Hua, Jianying Jin, Tieming Xie, Haiping Zhao, Feng Yan, Junjun Shen, Yihui Huang, Wangye Zheng, Junrong Yan, Xiaoying Wu, Song Wang, Qiuxiang Ou, Yang Shao, Wei Wu, Wei Zhuo, Jieer Ying

“…In vitro and in vivo experiments were conducted to investigate the role of identified biomarkers in BTC. Results Mutations in TP53, BRCA2, cytokine genes, and high tumor mutation burden were significantly associated with treatment response. …”
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Impacts of sulfate polysaccharide JCS1S2 on retinal neovascularization in oxygen-induced retinopathy rats by Yang Bai, Rui Wang, Can Jin, Can Jin, Lili Wang, Yun Tang, Han Wang, Kan Ding, Kan Ding, Shanjun Cai

“…Group III was further subdivided into three subgroups treated with different concentrations of JCS1S2 (10 μg/μL, 20 μg/μL, and 40 μg/μL). After finding the optimal concentration of JCS1S2 by ADP and HE, PCR, Western blot and transcriptome sequencing were used to analyze the role of JCS1S2 in Müller cells of OIR rats and rat retinas. …”
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Enhancing water use efficiency: Insights from hydrological variability encounter of multiple water sources and implications for terminal Lake management in arid regions by Kun Liu, Yunfei Chen, Bin Wu, Hailiang Xu, Abdul Waheed, Fan Gao, Bing He, Long Zhou, Jie Wu, Qin Zhang, Jinhao Ju

“…This study underscores the critical role of strengthening multi-source water coordination and deepening understanding the dynamics of wet-dry runoff transitions to enhance water security and optimize resource management in arid regions.…”
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Microscopic Structure and Strength Variation Patterns of Fiber-Modified Coarse-Grained Sulfate Saline Soil by DING Jin-hua, LI Jia-jun, GONG Miao-miao, LUO Wei, LI Teng-fei

“…Lignin fiber increased the optimal water content in high-salt soils, promoting nearly complete salt dissolution. …”
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When gender matters: inequalities in health services utilization and risk factors monitoring after acute myocardial infarction by Irene López-Ferreruela, Irene López-Ferreruela, Antonio Gimeno-Miguel, Antonio Gimeno-Miguel, Clara Laguna-Berna, Clara Laguna-Berna, Sara Malo, Sara Malo, Sara Malo, Sara Castel-Feced, Sara Castel-Feced, María José Rabanaque, María José Rabanaque, María José Rabanaque, Isabel Aguilar-Palacio, Isabel Aguilar-Palacio, Isabel Aguilar-Palacio

“…Despite European guidelines highlighting the importance of cardiovascular risk factor (CVRF) management and optimal healthcare utilization, inequalities persist, particularly between genders. …”
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Perceived workplace stressors and professional experiences of clinical embryologists working in Italy and Spain: a pilot qualitative study by Giancarlo Astro, Monica Gatti, Mauro Costa, Arianna Cosmelli, Alessandra Alteri, Attilio Anastasi, Attilio Anastasi, Danilo Cimadomo, Danilo Cimadomo, Lucia De Santis, Lucia De Santis, Francesca Gioia Klinger, Francesca Gioia Klinger, Emanuele Licata, Emanuele Licata, Laura Sosa Fernandez, Laura Sosa Fernandez, Giovanna Tomasi, Giovanna Tomasi, Elena Vegni, Irene Cuevas Sáiz, Nicolas Prados, Nicolas Prados, Nicolas Prados, Valerio Pisaturo, Valerio Pisaturo

“…IntroductionThe well being of clinical embryologists remains a largely neglected aspect in the field of reproductive medicine, despite their critical role in the success of medically assisted reproduction (MAR) procedures. …”
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Silencing of RpATG8 impairs the biogenesis of maternal autophagosomes in vitellogenic oocytes, but does not interrupt follicular atresia in the insect vector Rhodnius prolixus. by Jéssica Pereira, Calebe Diogo, Ariene Fonseca, Larissa Bomfim, Pedro Cardoso, Anna Santos, Uilla Dittz, Kildare Miranda, Wanderley de Souza, Adriana Gioda, Enrique R D Calderon, Luciana Araripe, Rafaela Bruno, Isabela Ramos

“…The autophagy-related protein 8 (ATG8) is conjugated to the autophagic membrane and has a key role in the elongation and closure of the autophagosome. …”
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Brain MRI and regional vulnerabilities to radiation necrosis: investigating the impact of stereotactic radiotherapy in brain metastases treatment by Carlo A. Mallio, Carlo A. Mallio, Ugo Ferrari, Ugo Ferrari, Gianfranco Di Gennaro, Matteo Pileri, Matteo Pileri, Caterina Bernetti, Caterina Bernetti, Enrica Polo, Enrica Polo, Emma Gangemi, Francesca Giannetti, Francesca Giannetti, Paolo Matteucci, Paolo Matteucci, Bruno Beomonte Zobel, Bruno Beomonte Zobel, Edy Ippolito, Edy Ippolito, Sara Ramella, Sara Ramella

“…These findings might have implications for optimizing radiotherapy planning and developing targeted strategies to mitigate the risk of radiation necrosis. …”
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Postoperative complications after central nervous system tumor resection in pediatric patients admitted to an intensive care unit in Colombia by Rubén E. Lasso-Palomino, Rubén E. Lasso-Palomino, Inés Elvira Gómez, Inés Elvira Gómez, María José Soto-Aparicio, Andrés Gempeler, Andrés Gempeler, Andrés Pombo-Jiménez, Melissa Gómez-Toro, Valentina Rojas-Robledo, María Alejandra Jiménez-Arévalo, Karla Alejandra Bastidas-Toro, Jimena Sierra, Sofía Martínez-Betancur, Sofía Martínez-Betancur, Camila Ariza-Insignares, Isabella Montaño-Vivas, Ximena Castro, Ximena Castro, Anita V. Arias

“…Our findings emphasize the importance of tailored interventions and multidisciplinary collaboration to optimize clinical outcomes. Future data comparison from centers sharing similar characteristics will play a crucial role in identifying best practices and enhancing outcomes globally.…”
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Magnetic Resonance Imaging in Multiple Sclerosis: An Analysis of the Implementation of the Portuguese Consensus by Ricardo Soares dos Reis, Alyne Cordeiro, Ana João Marques, Ana Rita Castro, Cristiana Silva, Duarte Carapinha, Francisca Ferreira, Miguel Schön, Daniela Jardim Pereira, João Paulo Gabriel, Luís Ruano, Mariana Santos, Miguel Grunho, Mónica Santos, José Vale, Maria José Sá

“… Introduction: Magnetic resonance imaging (MRI) plays a critical role in diagnosing and monitoring people with multiple sclerosis (MS). …”
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RAS–p110α signalling in macrophages is required for effective inflammatory response and resolution of inflammation by Alejandro Rosell, Agata Adelajda Krygowska, Marta Alcón Pérez, Cristina Cuesta, Mathieu-Benoit Voisin, Juan de Paz, Héctor Sanz-Fraile, Vinothini Rajeeve, Ana Carreras-González, Alberto Berral-González, Ottilie Swinyard, Enrique Gabandé-Rodríguez, Julian Downward, Jordi Alcaraz, Juan Anguita, Carmen García-Macías, Javier De Las Rivas, Pedro R Cutillas, Esther Castellano Sanchez

“…This discovery uncovers a previously unknown role of the p110α isoform in immune regulation within macrophages, offering insight into the complex mechanisms governing their function during inflammation and opening new avenues for modulating inflammatory responses.…”
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The Effect of Systemic Inflammation and Clinicopathologic Features on Survival in Malignant Pleural Mesothelioma: A Multicenter Analysis by Nadiye Sever, Sedat Yıldırım, Ali Fuat Gurbuz, Delyadil Karakaş Kılıç, Esra Zeynelgil, Yunus Emre Altintaş, Berivan Deniz Çimik, Yeşim Ağyol, Ali Kaan Güren, Pınar Erel, Erkam Kocaaslan, Burak Paçacı, Mustafa Alperen Tunç, Abdussamet Çelebi, Nazım Can Demircan, Selver Işık, Rukiye Arıkan, Murat Araz, Serdar Karakaya, Murat Sarı, Osman Köstek, İbrahim Vedat Bayoğlu

“…Epithelioid histology and early-stage disease are associated with significantly longer survival, underscoring the critical role of early detection in improving patient outcomes.…”
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Anatomical heterogeneity in low-grade and high-grade gliomas: A multiscale perspective by Shengpeng Liang, Nuo Dong, Yumin Chen, Yang Yang, Haibing Xu

“…Moreover, the high node strength played a critical role in the distinct spatial distribution of glioma. …”
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A Rare Case of Exophiala Dermatitidis Isolation in a Patient with Non-Cystic Fibrosis Bronchiectasis: Colonization or True Infection? by Francesco Rocco Bertuccio, Nicola Baio, Simone Montini, Valentina Ferroni, Vittorio Chino, Lucrezia Pisanu, Marianna Russo, Ilaria Giana, Elisabetta Gallo, Lorenzo Arlando, Klodjana Mucaj, Mitela Tafa, Maria Arminio, Emanuela De Stefano, Alessandro Cascina, Angelo Guido Corsico, Giulia Maria Stella, Valentina Conio

“…<b>Conclusions:</b> This report highlights the potential role of <i>E. dermatitidis</i> as an under-recognized respiratory pathogen in NCFB and the importance of a multidisciplinary, individualized approach to diagnosis and treatment. …”
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Low transthyretin is associated with the poor prognosis of colorectal cancer by Zhe Zhang, Zhe Zhang, Zhe Zhang, Chenhao Hu, Chenhao Hu, Chenhao Hu, Feiyu Shi, Feiyu Shi, Feiyu Shi, Lei Zhang, Lei Zhang, Lei Zhang, Ya Wang, Ya Wang, Yujie Zhang, Yujie Zhang, Yujie Zhang, Xiaojiang Zhang, Xiaojiang Zhang, Xiaojiang Zhang, Junjun She, Junjun She, Junjun She

“…The X-tile program was used to determine the optimal cut-off value. Cox proportional hazard regression analysis was conducted to evaluate the correlation between the TTR and the cumulative incidence of cancer-specific survival (CSS). …”
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Water Stress Promotes Secondary Sexual Dimorphism in Ecophysiological Traits of Papaya Seedlings by Ingrid Trancoso, Guilherme A. R. de Souza, João Vitor Paravidini de Souza, Rosana Maria dos Santos Nani de Miranda, Diesily de Andrade Neves, Miroslava Rakocevic, Eliemar Campostrini

“…Plant genders could express different functional strategies to compensate for different reproductive costs, as females have an additional role in fruit and seed production. Secondary sexual dimorphism (SSD) expression is frequently greater under stress than under optimal growth conditions. …”
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Scopus-based bibliometric analysis of research trends in silage feed and its impact on rumen fermentation in ruminants by Tri Rachmanto Prihambodo, Randi Mulianda, Wulandari Wulandari, Santika Anggrahini, Novia Qomariyah, Andi Ella, Erna Winarti, Yenni Yusriani, Suyatno Suyatno, Jhon Firison, Deni Fitra, Anwar Efendi Harahap, Dinda Ayu Permata Sari, Taufik Hidayat, Anuraga Jayanegara

“…Background and Aim: Silage plays a pivotal role in ruminant nutrition, significantly influencing rumen fermentation, animal productivity, and environmental sustainability. …”
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Tumor-derived lactate inhibit the efficacy of lenvatinib through regulating PD-L1 expression on neutrophil in hepatocellular carcinoma by Ming Zhao, Qifeng Chen, Wenhua Lu, Ning Lyu, Zhenfeng Zhang, Qiankun Xie, Haijing Deng, Anna Kan, Meng He, Shuang Qiao, Shaolong Li, Huiming Chen, Jinfa Lai, Xiongying Jiang, Shousheng Liu

“…Background Neutrophils play a controversial role in tumor development. The function of programmed cell death-1 ligand (PD-L1+) neutrophils, however, may inhibit the cytotoxicity of anti-tumor immunity. …”
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