Unveiling the Regulatory Mechanism of Tibetan Pigs Adipogenesis Mediated by WNT16: From Differential Phenotypes to the Application of Multi-Omics Approaches by Qiuyan Huang, Kunli Zhang, Fanming Meng, Sen Lin, Chun Hong, Xinming Li, Baohong Li, Jie Wu, Haiyun Xin, Chuanhuo Hu, Xiangxing Zhu, Dongsheng Tang, Yangli Pei, Sutian Wang

“…The aim of this study is to investigate the physiological characteristics and regulatory mechanisms of porcine intramuscular fat (IMF), subcutaneous fat (take back fat (BF), for example), and visceral fat (take perienteric fat (PF), for example) to address the challenge of optimizing meat quality without excessive fat deposition. …”
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Weight-adjusted waist index is associated with risk of poor bone quality rather than low bone mass in patients with type 2 diabetes by Dehuai Feng, Junying Liu, Ningning Bai, Shujuan Chen, Liming Zhou, Xinlian He, Keli Zhao, Shaobin Wang, Jinyang Wan, Sheng Ouyang, Yiting Zheng, Zhimao Cai, Dewen Yan, Ling Chen

“…This study aimed to investigate the clinical and biochemical determinants of BMD and TBS in patients with T2D, with a focus on elucidating the role of weight-adjusted waist index (WWI) in modulating bone mass and quality in this cohort. …”
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Lipid Metabolism and Breast Cancer: A Narrative Review of the Prognostic Implications and Chemotherapy-Induced Dyslipidemia by Ionut Flaviu Faur, Amadeus Dobrescu, Ioana Adelina Clim, Paul Pasca, Cosmin Burta, Marco Marian, Dan Brebu, Andreea-Adriana Neamtu, Vlad Braicu, Talpai Tamas, Ciprian Duta, Bogdan Totolici

“…<b>Introduction:</b> Lipid metabolism plays a crucial role in breast cancer’s progression, treatment response, and prognosis. …”
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Prognostic Factors and Treatment Outcomes in Gallbladder Cancer Patients Undergoing Curative Surgery: A Multicenter Retrospective Cohort Study by Bowen Xu, Yanjiang Yin, Jianping Chang, Zhiyu Li, Xinyu Bi, Jianqiang Cai, Xiao Chen

“…There is limited consensus regarding the extent of lymphadenectomy, hepatic resection, and the role of adjuvant therapies. Identifying prognostic factors and optimizing treatment strategies are critical for improving outcomes. …”
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HPV-negative oropharyngeal carcinoma as a separate prognostkally unfavorable form of cancer, requiring new approaches to treatment (case report) by A. R. Gevorkov, A. V. Boyko, A. P. Polyakov, L. V. Bolotina, N. N. Volchenko, I. V. Rebrikova, A. М. Lemeshko, S. V. Shashkov

“…Both overall management strategy and recommended standard scheme of CRT should be revised; the role of surgical and chemotherapeutic components of treatment should also be reassessed. …”
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Instantaneous dose rate as a crucial factor in reducing mortality and normal tissue toxicities in murine total-body irradiation: a comparative study of dose rate combinations by Hongyu Zhu, Shihua Liu, Jiaqi Qiu, Ankang Hu, Wanyi Zhou, Jian Wang, Weihang Gu, Yinuo Zhu, Hao Zha, Rong Xiang, Junli Li, Rui Qiu, Chong Zhao, Peng Huang, Xiaowu Deng

“…Conclusion Our findings underscore the pivotal role of instantaneous dose rate in reducing radiation damages. …”
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Impact of genetic risk and lifestyles on cardiovascular disease-free and total life expectancy: a cohort study by Dong Sun, Qiufen Sun, Yinqi Ding, Canqing Yu, Dianjianyi Sun, Yuanjie Pang, Pei Pei, Ling Yang, Iona Y. Millwood, Robin G. Walters, Huaidong Du, Jun Zhang, Dan Schmidt, Junshi Chen, Zhengming Chen, Liming Li, Jun Lv, the China Kadoorie Biobank Collaborative Group

“…Abstract Background Understanding the role of genetic risk and lifestyles on life expectancy (LE) without cardiovascular disease (CVD) and total LE may help optimize healthy aging strategies after taking genetic background into account. …”
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Mitigation of mycotoxin residues and activation of endogenous stem cells in broiler chickens using a toxin binder: Implications for meat safety and performance enhancement by Erma Safitri, Hery Purnobasuki, Tita Damayanti Lestari, Suzanita Utama, Rimayanti Rimayanti, Mirni Lamid, Mutmainah Wardatul Jannah, Siti Darodjah, Goo Jang, Mitsuhiro Takagi

“…Meanwhile, a dose of 1.1 g/kg yielded optimal growth performance and feed efficiency. These findings support the dual functional role of toxin binders in enhancing broiler meat safety and physiological resilience.…”
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Evolutionary dynamics of heparan sulfate utilization by SARS-CoV-2 by Shuhei Higuchi, Yafei Liu, Jun Shimizu, Chikako Ono, Yumi Itoh, Wataru Nakai, Hui Jin, Kazuki Kishida, Kazuo Takayama, Toru Okamoto, Yoshiko Murakami, Taroh Kinoshita, Yoshiharu Matsuura, Tatsuo Shioda, Hisashi Arase

“…These findings suggest that SARS-CoV-2 is evolving to enhance its infectivity by optimizing its interaction with cell surface heparan sulfate.IMPORTANCEThe Omicron variant has evolved to become highly infectious by acquiring numerous mutations. …”
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Yield and Quality of Walnuts Subjected to Deficit Irrigation in Mountainous Water-Starved Environments by Víctor Hugo Durán Zuazo, Belén Cárceles Rodríguez, Esther Sendra, Ángel Antonio Carbonell-Barrachina, Leontina Lipan, Francisca Hernández, Baltasar Gálvez Ruiz, Iván Francisco García-Tejero

“…Walnut (<i>Juglans regia</i> L.) exhibits a high sensitivity to water deficit, making it crucial to comprehend this characteristic in order to optimize irrigation strategies to improve its productivity. …”
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Loss of β2-integrin function results in metabolic reprogramming of dendritic cells, leading to increased dendritic cell functionality and anti-tumor responses by Heidi Harjunpää, Riku Somermäki, Guillem Saldo Rubio, Manlio Fusciello, Sara Feola, Imrul Faisal, Anni I Nieminen, Liang Wang, Marc Llort Asens, Hongxia Zhao, Ove Eriksson, Vincenzo Cerullo, Susanna C Fagerholm

“…DC-based immunotherapies are used in cancer treatment, but their functionality is not optimized and their clinical efficacy is currently limited. …”
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Association of bioelectrical impedance phase angle and nutritional status in patients undergoing pancreaticoduodenectomy by Jialing Li, Defu Hu, Yu Yan, Mengyu Yu, Hexing Hang, Hexing Hang, Yudong Qiu, Yudong Qiu, Dayu Chen, Xu Fu

“…The aims of this study is to investigate the role of PhA in assessing the nutritional status of patients undergoing PD and to propose new strategies for the perioperative nutritional management of these patients.MethodsOne hundred and seventy-three consecutive who underwent PD between March 2023 and September 2024 were evaluated and analyzed retrospectively. …”
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Inflammatory and nutritional markers predict response and prognosis of patients with locally advanced gastric cancer receiving neoadjuvant immunochemotherapy by Yiwen Sun, Mengjie Liang, Xingzhou Wang, Wenting Dong, ZhenShui Wu, Feng Sun, Xiaofeng Lu, Feng Wang, Song Liu, Meng Wang, Shichao Ai, Xiaofei Shen, Wenxian Guan

“…Abstract Background Metabolism plays an important role in the occurrence and development of gastric cancer, including in neoadjuvant immunochemotherapy. …”
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Small extracellular vesicles derived from mesenchymal stromal cells loaded with β-nicotinamide mononucleotide activate NAD+/SIRT3 signaling pathway-mediated mitochondrial autophagy... by Zixuan Sun, Jiali Li, Yuzhou Zheng, Jiaxin Zhang, Wenhuan Bai, Xinyi Deng, Zhijing Wu, XueZhong Xu, Wei Ding, Hui Qian, Yulin Tan

“…Notably, NMN-sEVs treatment increased intracellular NAD+ levels and SIRT3 expression, as well as rescued the inhibition of senescence-induced mitochondrial autophagy, suggesting a role for NMN-sEVs in the remodeling of mitochondrial function through mitochondrial autophagy. …”
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Enhancing Corn Image Resolution Captured by Unmanned Aerial Vehicles With the Aid of Deep Learning by Emilia Alves Nogueira, Bruno Moraes Rocha, Gabriel da Silva Vieira, Afonso Ueslei da Fonseca, Juliana Paula Felix, Antonio Oliveira-Jr, Fabrizzio Soares

“…The increasing global population has heightened the demand for food, making it crucial to optimize agricultural practices. As a versatile crop, corn plays a crucial role in global food security, particularly in countries like the United States, Brazil, China, and Argentina, where corn farming is a major economic driver. …”
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Determination of the prevalence and predictors of ventricular thrombus with assessment of the risk of systemic embolization to the CNS in patients after acute myocardial infarction... by Stepan Hudec, Martin Hutyra, Jan Precek, Jan Latal, Radomir Nykl, Miloslav Spacek, Martin Sluka, Daniel Sanak, Zbynek Tudos, Dalibor Pastucha, Milos Taborsky

“…The aim of this observational study was to determine the role of transthoracic echocardiography and cardiac markers in predicting the occurrence of LVT compared with a reference cardiac imaging (DE-CMR) and to determine the risk of systemic embolization to the CNS using brain MRA. …”
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Perceptions about chronic health conditions, multimorbidity and self-management practices in rural northeast South Africa: findings from a qualitative study by Edward Fottrell, Stephen Tollman, F Xavier Gómez-Olivé, Rochelle Burgess, Alisha N Wade, Audry Dube, Nicola Joan Christofides, Belinda J Njiro, Chodziwadziwa Whiteson Kabudula

“…Participants also highlighted the role of religion in the control of chronic disease risk factors and traditional treatments for uncommon conditions such as epilepsy. …”
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Rapid Detection of <i>PML::RARA</i> Fusions in Acute Promyelocytic Leukemia: CRISPR/Cas9 Nanopore Sequencing with Adaptive Sampling by William Middlezong, Victoria Stinnett, Michael Phan, Brian Phan, Laura Morsberger, Melanie Klausner, Jen Ghabrial, Natalie DeMetrick, Jing Zhu, Trisha James, Aparna Pallavajjala, Christopher D. Gocke, Maria R. Baer, Ying S. Zou

“…Understanding the involvement of additional genes and positional effects related to the <i>PML</i> and <i>RARA</i> genes could shed light on their role in APL and may aid in the development of novel targeted therapies.…”
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Genome-Wide Identification and Expression Analysis of the HSP90 Gene Family in Relation to Developmental and Abiotic Stress in Ginger (<i>Zingiber officinale</i> Roscoe) by Daoyan Xiao, Yajun Jiang, Zhaofei Wang, Xingyue Li, Hui Li, Shihao Tang, Jiling Zhang, Maoqin Xia, Meixia Zhang, Xingfeng Deng, Hong-Lei Li, Huanfang Liu

“…This study investigates the HSP90 gene family in ginger and its crucial role in the plant’s responses to abiotic stresses. …”
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In situ estimation of active dispersal abilities in reef fish early life stages using tracking technologies by Eliot Ruiz, Pierre‐Yves Pascal, Lucie Vanalderweireldt, Sébastien Cordonnier, Amélia Chatagnon, Pierre‐Louis Rault, Séverine Albouy‐Boyer, Juliette Silhol, Raphaël Thomas, Charlotte R. Dromard, Loïc Pellissier, Thomas Le Berre, Jacques Panfili, Camille Albouy, Fabien Leprieur

“…Abstract Most reef fishes possess an early pelagic stage that ensures the crucial role of maintaining connectivity between distant populations, as movements of older demersal stages are generally restricted. …”
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