Abstract 033: Trends in Cerebral Angiogram Utilization for Patients with Infective Endocarditis: A Nationwide Analysis by Giana Dawod, Alis J. Dicpinigaitis, Paulina Díaz, Clinton Ehidom, Nicholas Janocko, Alexander E. Merkler

“…Future directions should focus on understanding the appropriate timing of imaging in relation to the patient’s disease course to optimize inpatient care.…”
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Development of the Composition and Technology for Production a Solid Dispersion System by Hot Melt Extrusion to Increase the Bioavailability of the Active Substance by K. A. Gusev, D. N. Maimistov, V. I. Pavlovsky, A. R. Aliev, A. V. Pavlovsky, O. V. Ivanova, D. O. Tsyrenov, E. V. Flisyuk

“…The solubility of an active pharmaceutical ingredient plays a major role in drug absorption. Hot melt extrusion is a batch or continuous process that allows creating solid dispersion systems based on various carriers in order to increase solubility and bioavailability of active substances. …”
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Prognostic analysis of esophageal cancer patients after neoadjuvant therapy by Jing Dong, Cheng Li, Bingxiang Wang, Yang Li, Suzhen Wang, Hongxia Cui, Min Gao

“…BackgroundNeoadjuvant therapy is widely used for esophageal cancer (EC), but optimal treatment regimens and predictive factors for outcomes remain unclear. …”
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Innovative strategies to optimise colorectal cancer immunotherapy through molecular mechanism insights by Quanjun Lin, Zhiqiang Wang, Jue Wang, Ming Xu, Xinyi Zhang, Peng Sun, Yihang Yuan

“…Additionally, in vitro experiments were performed on DLX2, a gene strongly associated with poor prognosis, to validate its potential role as a therapeutic target in CRC progression.ResultsEight major cell types were identified across the tissue samples. …”
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SPP1+ tumor-associated macrophages define a high-risk subgroup and inform personalized therapy in hepatocellular carcinoma by Wei-Xuan Xu, Ya-Mei Ye, Jia-Lin Chen, Xin-Ying Guo, Chen Li, Juan Luo, Lin-Bin Lu, Xiong Chen

“…SPP1 blockade emerged as a strategy for counteracting immunosuppression, and cluster-specific therapies may optimize the management of HCC.…”
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Glycated albumin levels in the third trimester of women with gestational diabetes mellitus are associated with adverse pregnancy-related outcomes by Yueshuai Pan, Ruting Gu, Qianqian Li, Jingyuan Wang, Yan Zhang, Lin Zhao, Yue Wu, Lili Wei

“…In the future, the potential role of GA as a predictor of adverse pregnancy outcomes need to be further confirmed and explored in GDM women.…”
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DAPSI(W)R(M) put into practice for a nature-based solution: Framework applied to the coastbusters approach by Alexia Semeraro, Rémi Dupont, Vicky Stratigaki, Tomas Sterckx, Gert Van Hoey

“…Our results underscore the importance of a favorable institutional environment for NbS and suggest that public acceptance and stakeholder involvement play a crucial role in successful implementation. This study contributes to the understanding and operationalization of Nature-based Solutions in coastal management.…”
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Associations Between the Polymorphisms in the Coding Sequence of SLCO1B1 and Blood Lipid Levels Before and After Treatment by Atorvastatin in the Chinese Han Adults with Dyslipidem... by Chen C, Tian Y, Jia F, Feng M, Zhang G, Li Q, Zhang Y, Sun N, Hu S, Ji Z

“…The findings underscore the crucial role of the rs2306283 polymorphism in the response to atorvastatin’s efficacy, highlighting the significance of pharmacogenomics in personalized medicine. …”
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Improving Organic Acid Secretion of <i>Aspergillus niger</i> by Overexpression C4-Dicarboxylic Acid Transporters by Yiyang Tan, Shutong Liu, Sheng Wu, Xiaolu Wang, Depei Wang, Xianli Xue

“…The objective of this study was to investigate the specificity of six DCTs (DCT1-5 and C4t318) from <i>Aspergillus niger</i> or <i>Aspergillus oryzae</i>, focusing on their role in different production strategies for C4-dicarboxylic acids. …”
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Investigation of the Impact of Soil Physicochemical Properties and Microbial Communities on the Successful Cultivation of Morchella in Greenhouses by Xinhai Liu, Bo Yin, Liqiang Meng, Xiaoyu Zhao, Jialong Wang, Rui Liu, Lina Hu, Xiangxiang Wang, Yu Liu, Yinpeng Ma

“…Furthermore, the construction of the fungal-bacterial co-occurrence network revealed that the NM soil exhibited a higher number of nodes and greater network stability, suggesting that its complex microbial community structure may play a crucial role in the successful cultivation of Morchella. …”
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Medial meniscus injury changed plantar pressure distributions and decreased posture stability especially in those with varus alignment: a cross-sectional study based on a wearable... by Ting Zhu, Fangyuan Ding, Rui Chen, Haoyang Kang, Rui Guo, Xiaoming Wu, Dong Jiang

“…While studies focus on joint degeneration, the role of extrinsic factors such as postural control remains underexplored. …”
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Cutaneous Changes Beyond Psoriasis: The Impact of Biologic Therapies on Angiomas and Solar Lentigines by Florin Ciprian Bujoreanu, Diana Sabina Radaschin, Ana Fulga, Laura Bujoreanu Bezman, Carmen Tiutiuca, Mihaela Crăescu, Carmen Pantiș, Elena Niculet, Alina Pleșea Condratovici, Alin Laurențiu Tatu

“…Given these associations, further research is needed to elucidate the underlying mechanisms and refine treatment strategies to optimize dermatologic care for psoriasis patients.…”
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PENERAPAN GREEN BUILDING DI PERKANTORAN MENARA SUARA MERDEKA, SEMARANG by Soraya Rizky Nabilla

“…Building users play a role in green behavior that supports saving energy use. …”
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People with dementia and informal caregivers’ perceptions of barriers and facilitators to implementing a behavioral activation intervention: a qualitative study using Normalization... by Frida Svedin, Oscar Blomberg, Anders Brantnell, Paul Farrand, Louise von Essen, Anna Cristina Åberg, Joanne Woodford

“…Involving patients and informal caregivers may be particularly important for low-intensity interventions, given the active role they are expected to adopt for successful intervention implementation, e.g., they are seen as active agents as opposed to passive recipients. …”
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Enhancing Fracture Detection in Remote Settings: Evaluating the Efficacy of FIXUS AI Deep Learning Algorithms in Identifying Fifth Metatarsal Fractures Using Mixed-Quality X-rays by Atta Taseh MD, Alireza Gholipour PhD, Mani Eftekhari, Alireza Ebrahimi MD, Alexandra F. Flaherty MD, MS, Alexandra F. Flaherty MD, MS, Sumner Jones, Varun Nukala, Gregory R. Waryasz MD, Daniel Guss MD, MBA, John Y. Kwon MD, Christopher W. DiGiovanni MD, Lorena Bejarano-Pineda MD, Soheil Ashkani-Esfahani MD

“…Conclusion: This study highlights the crucial role of image quality in developing deep learning models for detecting fifth metatarsal fractures. …”
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Synthesis and properties of 2-(4-phenyl-5-(((5-phenylamino-1,3,4-thiadiazole-2-yl)thio)methyl)-1,2,4-triazole-3-yl)thio)ethanoic acid and its salts by A. S. Hotsulia, S. O. Fedotov

“…During the work, the method of obtaining 2-((4-phenyl-5-(((5-phenylamino-1,3,4-thiadiazole-2-yl)thio)methyl)-1,2,4-triazole-3-yl)thio)ethanoic acids was optimized. The role of the reaction medium at this stage was played by water. …”
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The metabolomic approach to the complex biochemical characteristics of cole <i>Brassica oleracea</i> L. by Alla E. Solovyeva, Tatiana V. Shelenga, Anna M. Artemyeva

“…Samples with the optimal component composition for balanced human nutrition, which are proposed to be used in breeding for quality, including obtaining varieties for healthy (functional) and therapeutic and prophylactic nutrition of the population of theRussian Federation were found.…”
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A Novel pH-Responsive Nano-Sized Lanthanum-Doped Polyvinyl Alcohol-Carbon Quantum Dot Composite for Root Canal Irrigation by Yu L, Zhang C, Yang J, Li L

“…Chemical irrigants play a crucial role in complementing mechanical instrumentation in ensuring adequate disinfection. …”
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Donor and recipient genetic variants in drug metabolizing enzymes and transporters affect early tacrolimus pharmacokinetics after liver transplantation by Alexandra D. Ladd, Isabella Angeli-Pahim, Duncan Lewis, Curtis Warren, Satyavardhan Nittu, Jatinder Lamba, Sergio Duarte, Ali Zarrinpar

“…These findings demonstrate that genetic polymorphisms in both donor and recipient significantly affect tacrolimus dose requirements and the ability to maintain the target therapeutic tacrolimus levels in the immediate post-transplant period, emphasizing the role of precision medicine in optimizing immunosuppression therapeutic drug dosing.…”
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Research status and frontiers in liver cancer immunotherapy: a bibliometric perspective on highly cited literature by Pan Su, Yeqiong Han, Jindong Yi, Yu Hou, Yao Xiao, Yao Xiao, Yao Xiao

“…In the future, it is necessary to optimize treatment resistance solutions, integrate interdisciplinary resources, and promote the development of precision and personalized treatment.…”
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