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12641
Diagnosis of hypertonicity of the masticatory muscles at a dental appointment
Published 2021-10-01“…In the study of this area, the main role is played by the clinician, only if all the diagnostically valuable information is available, it is possible to formulate an optimal treatment plan and avoid aggravation of the patient's condition due to incorrect diagnosis and treatment.Conclusions. …”
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12642
Advances in cancer immunotherapy: historical perspectives, current developments, and future directions
Published 2025-05-01“…Key immunotherapeutic strategies, such as cancer vaccines, oncolytic viruses, adoptive cell transfer, and ICIs, are discussed in detail. Additionally, the role of nanotechnology, cytokines, chemokines, and adjuvants in enhancing the precision and efficacy of immunotherapies were explored. …”
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12643
Investigating the temperature-dependent selectivity of CO2 reduction on Ru-cluster catalysts supported by MXene
Published 2025-05-01“…Electronic structure analysis revealed that the orbital interactions between the Ru4 cluster and CO2 play a pivotal role in determining the adsorption configuration of the CO2 molecule. …”
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12644
H2MV (v1.0): global physically constrained deep learning water cycle model with vegetation
Published 2025-05-01“…These parameters have an explicit role to model soil moisture (SM) storage and the partitioning of evapotranspiration (ET). …”
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12645
Enhancement of Immune Responses by Guanosine-Based Particles in DNA Plasmid Formulations against Infectious Diseases
Published 2019-01-01“…In the present study, we examined the role of “Supramolecular Hacky Sacks” (SHS) particles, made via the hierarchical self-assembly of a guanosine derivative, as a novel immunomodulator for DNA plasmid preparations. …”
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12646
Impact of Hematopoietic Stem Cell Transplantation on PD-1 Blockade Efficacy in Relapsed/Refractory Hodgkin’s Lymphoma
Published 2025-04-01“…PD-1 inhibitors have shown efficacy, but the role of hematopoietic stem cell transplantation (HSCT) following PD-1 blockade remains uncertain. …”
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12647
A cross-sectional study evaluating insulin injection techniques and the impact of instructions from various healthcare professionals on insulin users in the southern region of Saud...
Published 2025-05-01“…Background It is evident that proper use of the insulin injection technique (IIT) is important for optimizing the efficacy of the therapy. Despite the readily available manufacturers’ instructions, healthcare professionals (HCPs) play a major role in educating patients. …”
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12648
Heat transfer in magneto-hybrid nanofluids with viscous and joule dissipation: a successive over relaxation analysis
Published 2025-09-01“…It is observed that induced magnetic field intensity increases with the coupling parameter, highlighting its significant role in magneto-hybrid nanofluids. Tables are arranged to demonstrate shear stress, couple stress, and heat transfer rate. …”
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12649
Cell biomechanics on muscle atrophy: from intricate mechanisms to therapeutic frontiers
Published 2025-12-01“…Although core molecular pathways and cellular changes are well characterized, the role of mechanical cues in modulating these mechanisms remains underexplored.Main Findings Our review reveals five convergent atrophy drivers—mechanical unloading, ECM alterations, mitochondrial dysfunction/oxidative stress, inflammation, and endocrine imbalance—that converge on inhibited mTORC1 signaling, activated FoxO/UPS/autophagy, and impaired satellite‐cell function. …”
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12650
Targeting Biomarkers of Proliferation and Inflammation (Ki67, p53, and COX-2) in Actinic Keratoses with Photodynamic Therapy
Published 2025-06-01“…Further studies are required to optimize PDT protocols.…”
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12651
Spatio-temporal scale evaluation of landscape visual quality in urban near-natural plant communities: A nomogram visualization approach
Published 2025-07-01“…Some qualitative indicators showed higher influence levels when at “medium” states, indicating that maintaining reasonable indicator levels plays an important role in enhancing LVQ. The research results provide intuitive, quantifiable scientific evidence for urban designers and planners, helping to optimize plant configuration in urban green spaces and improve overall landscape quality. …”
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12652
Astaxanthin Mitigates ADHD Symptoms in Spontaneously Hypertensive Rats via Dopaminergic Modulation and Brain–Gut Axis Regulation
Published 2025-04-01“…Biochemical analyses were conducted to evaluate changes in the levels of various neurotrophic factors, while histological examinations were performed to assess neuroprotective effects. Additionally, the role of ASTA in the brain–gut axis was investigated. …”
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12653
Hydrocarbon accumulation characteristics and main controlling factors of major salt-bearing basins in Central Asia
Published 2025-03-01“…Additionally, salt windows induced by deep faults, gypsum-salt pinch-out zones, and salt tectonic activities facilitate vertical migration of hydrocarbons in sub-salt source rocks, playing a crucial role in large-scale hydrocarbon accumulation in supra-salt rock sequences.…”
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12654
Determinants of hypertension-related knowledge, attitude, and practices (KAP) among caregivers in Neno, rural Malawi: A cross-sectional study
Published 2025-01-01“…Caregivers play a crucial role in ensuring optimal care for hypertensive patients and reducing associated complications. …”
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12655
Predictors and Clinical Impacts of Impaired Heart Rate Variability in Women with Breast Cancer
Published 2025-03-01“…Hypertension plays a crucial role in the deterioration of HRV in patients with BC, and de novo AF is more common in patients with impaired HRV. …”
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12656
Should South Asian Stock Market Investors Think Globally? Investigating Safe Haven Properties and Hedging Effectiveness
Published 2024-11-01“…Moreover, these results hold significant implications for investors seeking to optimize portfolios and manage risk, as well as for policymakers aiming to strengthen regional market resilience. …”
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12657
Multi-omics characterization of aflatoxigenic Aspergillus from grains and rhizosphere of maize across agroecological zones of Cameroon
Published 2025-05-01“…This finding highlights a potential avenue for biocontrol, warranting further research to elucidate the underlying metabolic pathways and optimize conditions for practical application.…”
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12658
Precise Modulation of Reorganization Energy through Methyl Substitution for High Performance Organic Solar Cells
Published 2025-08-01“…This enhancement is attributed to optimized molecular stacking, improved film morphology, and reduced trap‐assisted recombination. …”
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Effects of neuromuscular training on tennis players: a systematic review and meta-analysis
Published 2025-07-01“…Furthermore, age appeared to play a role, as players over 18 years showed greater gains in service velocity and power compared to their younger counterparts. …”
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12660
Clinical and Preclinical Evidence on a Novel Percutaneous Pulsatile Ventricular Assist Device (PulseCath): Protocol for a Scoping Review
Published 2025-05-01“…ABSTRACT Background and Aims Temporary mechanical circulatory support (tMCS) devices play a crucial role in improving survival for patients with hemodynamic instability by providing cardiac assistance, and may serve as either a bridge to recovery or destination therapy. …”
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