Analysis of Antioxidant Activity and Volatile Components in Rapeseed Flower-Enriched Persimmon Wine by Zhijie Li, Kaishuo Sun, Yanyan Wang, Fang Yu, Zhiwen Liu

“…These findings also offer theoretical support for a deeper understanding of the fermentation mechanisms of persimmon wine while providing practical guidance to optimize production processes, ultimately improving both product flavor and stability. …”
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Bridging intentions and outcomes: a program theory approach to residency accreditation standards by Dana Tenne-Fishbain, Yehuda L. Danon, Rachel Nissanholz-Gannot

“…Several critical components were identified as missing from current standards, reflecting gaps in educational processes, oversight mechanisms, and organizational responsibilities. …”
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Transposon-directed insertion-site sequencing (TraDIS) analysis of Enterococcus faecium using nanopore sequencing and a WebAssembly analysis platform by Alexandra L. Krause, Wytamma Wirth, Adrianna M. Turner, Louise Judd, Lucy Li, Willem van Schaik, Benjamin P. Howden, Glen P. Carter, Torsten Seemann, Ryan Wick, Timothy P. Stinear, Andrew H. Buultjens, Ian R. Monk

“…Our end-to-end platform for running TraDIS experiments in VREfm will permit accessible, genome-scale, forward genetic screens to probe molecular mechanisms of persistence and pathogenesis.IMPORTANCEThere are limited genetic tools specifically developed and optimized for function in Enterococcus faecium. …”
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Integrative transcriptomic-physiological analysis deciphers nitrogen-mediated carbon reallocation balancing growth and flavonoid metabolism in Epimedium pubescens by Shangnian Liu, Shangnian Liu, Xiaojing An, Xiaojing An, Chaoqun Xu, Dongmei He, Xianen Li, Caixia Chen, Baolin Guo, De Xu, Juan Huang

“…Weighted gene co-expression network analysis (WGCNA) identified the grey60 module as a hub coordinating carbon–nitrogen metabolism and mRNA processing. A tripartite regulatory network linking nitrogen-responsive genes (e.g., EpF3H, UGT), Icariin-type flavonoid/carbon metabolism (e.g., icariin, soluble sugars), and growth phenotypes (e.g., biomass, photosynthesis) elucidated how nitrogen optimizes the trade-off between medicinal quality and yield in E. pubescens. …”
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Preformulation Study of Carbamazepine Orally Disintegrating Tablets for Pediatric Patients Using Direct Compression and the SeDeM Diagram Tool: A Quality by Design Approach by Ricard Canadell-Heredia, Khadija Rouaz-El-Hajoui, Natalia Franco-Piedrahita, Pilar Pérez-Lozano, Marc Suñé-Pou, Josep María Suñé-Negre, Encarna García-Montoya

“…<b>Methods:</b> The development was carried out following a Quality by Design (QbD) approach, beginning with preformulation studies using the SeDeM expert system. Various co-processed excipients (PROSOLV^® ODT and PARTECK^® ODT) and non-co-processed excipients (L-HPC LH11 and L-HPC NBD-022) were evaluated. …”
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Assessing low free gas saturation via acoustic velocity in porous media by Rengang Shi, Rengang Shi, Jianwu Wang, Zhoutuo Wei, Zhoutuo Wei, Xinmin Ge, Xinmin Ge, Lei Xing, Lei Xing, Junfeng Zhao

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Antioxidants to Defend Healthy and Youthful Skin—Current Trends and Future Directions in Cosmetology by Anna Budzianowska, Katarzyna Banaś, Jaromir Budzianowski, Małgorzata Kikowska

“…Oxidative stress, primarily driven by an imbalance between reactive oxygen species (ROS) production and the skin’s defense mechanisms, accelerates aging processes, damages cellular structures, and compromises skin integrity. …”
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Metabolic syndrome, left ventricular diastolic dysfunction and heart failure with preserved ejective fraction by Dan Zhou, Shuisheng Lin, Zongchen Liu, Jiawen Yuan, Huixia Ren, Huiying Tan, Yi Guo, Xin Jiang

“…HFpEF encompasses a diverse range of pathological processes. In these patients, LVDD and elevated left ventricular filling pressure are the primary manifestations. …”
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Strategies for applying interpretable and explainable AI in real world IoT applications by Anber Abraheem Shlash Mohammad, Suleiman Ibrahim Shelash Mohammad, Badrea Al Oraini, Asokan Vasudevan, Ayman Hindieh, Ali Altarawneh, Muhammad Turki Alshurideh, Imad Ali

“…Most traditional AI models are regarded as "black boxes," in which understanding decision-making processes presents a challenge in crucial domains such as healthcare, smart cities, and industrial automation. …”
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Computational Modelling of Tunicamycin C Interaction with Potential Protein Targets: Perspectives from Inverse Docking with Molecular Dynamic Simulation by Vivash Naidoo, Ikechukwu Achilonu, Sheefa Mirza, Rodney Hull, Jeyalakshmi Kandhavelu, Marushka Soobben, Clement Penny

“…Protein glycosylation plays a crucial role in cancer biology, influencing essential cellular processes such as cell signalling, immune recognition, and tumour metastasis. …”
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A novel lactylation-related gene signature to predict prognosis and treatment response in lung adenocarcinoma by Hongyi Zhang, Hongyi Zhang, Yihao Liu, Xuanguang Li, Chen Ding, Chunqiu Xia, Hua Huang, Hongyu Liu, Jun Chen, Jun Chen

“…BackgroundLactylation, a novel post-translational modification, has emerged as a critical regulatory mechanism in various biological processes, including tumor progression. …”
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AASNet: A Novel Image Instance Segmentation Framework for Fine-Grained Fish Recognition via Linear Correlation Attention and Dynamic Adaptive Focal Loss by Jianlei Kong, Shunong Tang, Jiameng Feng, Lipo Mo, Xuebo Jin

“…Smart fisheries, integrating advanced technologies such as the Internet of Things (IoT), artificial intelligence (AI), and image processing, are pivotal in enhancing aquaculture efficiency, sustainability, and resource management by enabling real-time environmental monitoring, precision feeding, and disease prevention. …”
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A hybrid YOLO-UNet3D framework for automated protein particle annotation in Cryo-ET images by Ziyang Liu, Chunhong Yuan, Zixin Zhang, Xiang Zhou, Xiangyu Li, Zhen Tian, Yuting Pei, Zuowen Jiang, Zhikui Tian

“…In this study, we present a hybrid framework integrating You Only Look Once (YOLO) object detection with UNet3D volumetric segmentation, enhanced by density-based spatial clustering of applications with noise (DBSCAN) post-processing for automated protein particle annotation in cryo-ET volumes. …”
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Identification of sex-biased and gonadal developmental miRNAs during critical windows of early gonadal differentiation in the Chinese giant salamander (Andrias davidianus) by Shijun Yang, Xinlin Wang, Han Yang, Fan Yan, Lishan Xu, Zhijie Jian, Guangxiang Zhu, Qin Wang

“…Given that male CGS are larger than female, understanding the mechanisms behind gonadal differentiation and development is critical for optimizing production in aquaculture. …”
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Fast preparation of high-performance zero-valent iron biochar materials for the removal of arsenic and antimony pollutants utilizing waste wheat straws by Renxi Fang, Jing Peng, Lanxi Yu, Zepeng Wang, Keliang Pan, Chunjie Yan, Sen Zhou

“…The proposed technique overcomes the limitations of conventional tube furnace carbonization by achieving uniform heating with 97.94% reduced energy consumption (35.1 kW·h/kg vs 1706.8 kW·h/kg) and 99.61% shorter processing time (60 s vs 4.3 h). The optimized BC@20Fe0 had adsorption capacities of 100.0 mg/g and 151.5 mg/g for As(V) and Sb(V), respectively, which were about 1.6 and 2.5 times higher than those of the traditional biochar composites. …”
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Optically tunable catalytic cancer therapy using enzyme-like chiral plasmonic nanoparticles by Haeun Kang, Subin Yu, Ryeong Myeong Kim, Youngbi Kim, Sang Chul Shin, Dohyub Jang, Jeong Hyun Han, Sugyeong Hong, Eunice EunKyeong Kim, Sun Hee Kim, Dong June Ahn, Jeong Woo Han, Sehoon Kim, Ki Tae Nam, Luke P. Lee, Dong Ha Kim

“…Abstract Cascade enzymatic reactions in living organisms are fundamental reaction mechanisms in coordinating various complex biochemical processes such as metabolism, signal transduction, and gene regulation. …”
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Cross-Feature Hybrid Associative Priori Network for Pulsar Candidate Screening by Wei Luo, Xiaoyao Xie, Jiatao Jiang, Linyong Zhou, Zhijun Hu

“…CFHAPNet incorporates a novel architecture and strategies to integrate multi-class heterogeneous feature subimages from each candidate into multi-channel data processing. By implementing cross-attention mechanisms and other enhancements for multi-view feature interactions, the model significantly strengthens its ability to capture fine-grained image texture details and weak prior semantic information. …”
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NPI-WGNN: A Weighted Graph Neural Network Leveraging Centrality Measures and High-Order Common Neighbor Similarity for Accurate ncRNA–Protein Interaction Prediction by Fatemeh Khoushehgir, Zahra Noshad, Morteza Noshad, Sadegh Sulaimany

“…Predicting ncRNA–protein interactions (NPIs) is essential for understanding regulatory roles in cellular processes and disease mechanisms, yet experimental methods are costly and time-consuming. …”
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Hemolysis following Intravenous Immunoglobulin Therapy - Adverse effect to remember about by Sebastian Iwaniuk, Ignacy Maciejewski, Kinga Kowalik, Szymon Szypulski, Aleksandra Zielińska, Maria Michalska, Natalia Tylczyńska, Kinga Tylczyńska, Zuzanna Skiba, Jakub Skiba

“…Its pathophysiology involves both intravascular and extravascular mechanisms, influenced by factors such as blood group, IVIG dosage, and manufacturing processes.[11] While severe hemolysis is rare, mild cases are more common and may prolong hospitalizations.[12] Raising awareness of IVIG-related hemolysis can improve patient management and therapeutic decision-making, ultimately optimizing clinical outcomes. …”
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Comparative analysis of library preparation approaches for FFPE gene expression profiling and related recommendations by Sara Pignatta, Marcella Tazzari, Valentina Indio, Maria Maddalena Tumedei, Francesco Limarzi, Francesca Tauceri, Michela Tebaldi, Dalila Fanelli, Jenny Bulgarelli

“…We critically discuss these results in relation to RNA availability, technical performance, cost-effectiveness, processing time, and automation potential, offering practical guidance for selecting optimal RNA-seq strategies in clinical and translational research settings.…”
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