Preserving cognitive function in patients with Alzheimer's disease: The Alzheimer's disease neuroprotection research initiative (ADNRI) by Jie Liu, Heleen vanBeusekom, Xian‐Le Bu, Gong Chen, Paulo Henrique Rosado de Castro, Xiaochun Chen, Xiaowei Chen, Andrew N. Clarkson, Tracy D. Farr, Yuhong Fu, Jianping Jia, Jukka Jolkkonen, Woojin Scott Kim, Paula Korhonen, Shen Li, Yajie Liang, Guang‐Hui Liu, Guiyou Liu, Yu‐Hui Liu, Tarja Malm, Xiaobo Mao, Joaquim Miguel Oliveira, Mike M. Modo, Pedro Ramos‐Cabrer, Karsten Ruscher, Weihong Song, Jun Wang, Xuanyue Wang, Yun Wang, Haitao Wu, Lize Xiong, Yi Yang, Keqiang Ye, Jin‐Tai Yu, Xin‐Fu Zhou, Marietta Zille, Colin L. Masters, Piotr Walczak, Johannes Boltze, Xunming Ji, Yan‐Jiang Wang

“…To attain effective treatment for AD, it is necessary to (1) conduct extensive research on various mechanisms that cause neurodegeneration, including advances in neuroimaging techniques for earlier detection and a more precise characterization of molecular events at scales ranging from cellular to the full system level; (2) identify neuroprotective intervention targets against different neurodegeneration mechanisms; and (3) discover novel and optimal combinations of neuroprotective intervention strategies to maintain cognitive function in AD patients. …”
Get full text

Adaptive conflict resolution for IoT transactions: A reinforcement learning-based hybrid validation protocol by Mohammad A. Al Khaldy, Ahmad Nabot, Ahmad al-Qerem, Issam Jebreen, Abdulbasit A. Darem, Asma A. Alhashmi, Mohammad Alauthman, Amjad Aldweesh

“…Our key innovation lies in dynamically learning optimal scheduling policies that minimize transaction aborts while maximizing throughput under varying workload conditions. …”
Get full text

MEP-YOLOv5s: Small-Target Detection Model for Unmanned Aerial Vehicle-Captured Images by Shengbang Zhou, Song Zhang, Chuanqi Li, Shutian Liu, Dong Chen

Get full text

Research and application of unified cross-system data services for coal mines based on industrial internet platforms by WAN Maoquan, LI Hao, WANG Hao

“…Test results showed that, compared to the traditional distributed interface model, the proposed system optimized average data response time from 270 ms to 148 ms and improved data processing accuracy to 99.57%. …”
Get full text

DeepContainer: A Deep Learning-based Framework for Real-time Anomaly Detection in Cloud-Native Container Environments by Ke Xiong, Zhonghao Wu,  Xuzhong Jia

“…The proposed framework addresses critical security challenges in containerized infrastructures through an innovative integration of neural network architectures and automated response mechanisms. DeepContainer implements a multi-layered detection approach, combining feature engineering techniques with optimized deep learning models to identify security anomalies across diverse container workloads. …”
Get full text

The future of herbicide application: controlled-release formulations for enhanced agricultural sustainability by Vijeta Luhach, Jyoti Yadav, Poonam Barala, Parul Sangwan, Shashi Suhag, Vinita Hooda

“…Despite these innovations, challenges remain in standardizing processes, enhancing cost-effectiveness, and scaling up field applications. …”
Get full text

INNOVATIVE DESIGN AND FABRICATION OF FIXTURES FOR ENHANCED ULTRASONIC TESTING by Rahman Hakim, Windi Hapsari, Benndy Haddli Irawan

“…In conclusion, the fixture offers a safe, practical, and effective solution to optimize UT equipment calibration.…”
Get full text

A Novel Dual-Branch Global and Local Feature Extraction Network for SAR and Optical Image Registration by Xuanran Zhao, Yan Wu, Xin Hu, Zhikang Li, Ming Li

Get full text

Indole metabolism and its role in diabetic macrovascular and microvascular complications by W. Hu, C. Garrison, R. Prasad, M.E. Boulton, M.B. Grant

“…Tryptophan (Trp), an essential amino acid obtained through dietary sources, plays a crucial role in various physiological processes. The metabolism of Trp branches into three principal pathways: the serotonin pathway, the kynurenine pathway, and the indole pathway. …”
Get full text

COVID-19 and cognitive impairment: a review of the emerging evidence by Nicholas Aderinto, Gbolahan Olatunji, Emmanuel Kokori, Ikponmwosa Jude Ogieuhi, Ismaila Ajayi Yusuf, Emmanuel Egbunu, Bonaventure Michael Ukoaka, Adetola Emmanuel Babalola, Temiloluwa Oluwakorede Adefusi, John Ehi Aboje, Abdulrahmon Moradeyo

“…While the precise mechanisms remain under investigation, potential contributing factors include neuroinflammation, hypoxia, and psychological effects. …”
Get full text

Using convolutional neural networks for image semantic segmentation and object detection by Shuangmei Li, Chengning Huang

“…This study provides a more effective strategy for processing complex images by optimizing network structure and enhancing feature fusion.…”
Get full text

Enhancement of Phonological Memory Following Transcranial Magnetic Stimulation (TMS) by Matthew P. Kirschen, Mathew S. Davis-Ratner, Thomas E. Jerde, Pam Schraedley-Desmond, John E. Desmond

“…These results provide new insights into how the brain processes verbal information by establishing the necessity of the inferior parietal region for optimal phonological storage. …”
Get full text

Mass flow of PAHs and fragrance substances in the sedimentation tanks of conventional domestic wastewater treatment plant–trace organic chemicals passing through sedimentation tank... by Noriatsu Ozaki, Yiwen Mao, Tomonori Kindaichi, Akiyoshi Ohashi

“…The results provide a foundation for future research aimed at optimizing sedimentation mechanisms and exploring advanced treatment strategies to improve pollutant removal efficiency and environmental protection.…”
Get full text

Neural correlates of facial recognition deficits in autism spectrum disorder: a comprehensive review by Jianmei Liu, Jianmei Liu, Huihui Chen, Haijing Wang, Zhidan Wang

“…It has been found that the reduced activation in the FG and atypical activation of the amygdala and STS contribute to difficulties in processing facial cues, while increased reliance on the PFC for facial recognition tasks imposes a cognitive load. …”
Get full text

Novel co-culture model of T cells and midbrain organoids for investigating neurodegeneration in Parkinson’s disease by Elizaveta Gerasimova, Amke C. Beenen, Daniil Kachkin, Martin Regensburger, Sebastian Zundler, David B. Blumenthal, Gloria Lutzny-Geier, Beate Winner, Iryna Prots

“…Our work establishes a novel 3D cell co-culture model as a promising tool to investigate the effect of the adaptive immune system on the midbrain and can be used in future studies to address these processes in the context of PD.…”
Get full text

Assessment of efficiency of use of technologies of the distributed register in the conditions of digital economy by E. N. Klotchkova, L. V. Oveshnikova

“…The effectiveness of the use of distributed registry technologies in this study is considered in the financial industry, business processes of companies and international practice. …”
Get full text

Impact of blockchain technology on supply chain collaboration: A case study of JD Chain by Chen Zhirui

“…This paper examines JD’s blockchain framework and its impact on various supply chain functions, revealing that blockchain technology has markedly improved procurement efficiency, reduced costs, enhanced customer trust and sales revenue, optimized logistics operations, and streamlined management processes. …”
Get full text

Green Technology Game and Data-Driven Parameter Identification in the Digital Economy by Xiaofeng Li, Qun Zhao

“…These findings offer theoretical guidance for optimizing green policy design and identifying behavioral pathways, while establishing a foundation for data-driven modeling of dynamic evolutionary processes.…”
Get full text

Glucocorticoid receptor epigenetic activity in the heart by Olukunle Akinborewa, Mattia Quattrocelli

“…GR signaling influences essential processes within cardiomyocytes, including hypertrophy, calcium handling, and metabolic balance, all of which are vital for proper cardiac function. …”
Get full text

Collective predator evasion: Putting the criticality hypothesis to the test. by Pascal P Klamser, Pawel Romanczuk

“…Critical systems exhibit unique properties, which may benefit collective information processing such as maximal responsiveness to external stimuli. …”
Get full text