Spatial Distribution Characteristics and Co-occurrence Risk of Rainstorms and High Tide Levels in Guangzhou by Zheng Yangkun, Wang Feng, Wei Qiuying, Zhang Yun, Yang Fang, Hu Maochuan

“…By quantifying the joint probabilities of extreme rainfall and tidal events, we offered a scientific basis for optimizing flood control and drainage infrastructure. …”
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The mechanism of PGR-free direct organogenesis in Lycium ruthenicum leaf explants revealed by RNA-Seq and phytohormone metabolome co-analysis by Lujia Li, Yucheng Wang, Wenhui Liu, Yue Gao, Jiawen Wang, Huifang Lu, Weiman Xu, Qin-Mei Wang

“…These findings offer valuable theoretical guidance for optimizing direct organogenesis systems in plant leaves.…”
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Design and Research of a New Cold Storage: The Phase-Temperature Storage (PTS) to Reduce Evaporator Frosting by Lihua Duan, Yanli Zheng, Yunbin Jiang, Wenhan Li, Limei Li, Bin Liu, Bin Li, Xihong Li

“…Enhancing the surface area of the sub-storehouse and increasing convective wind speed are identified as key factors for improving convective heat transfer within the sub-storehouse. Moreover, the optimized design ensures a more uniform temperature distribution inside the sub-storehouse. …”
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Ecological Pea Production in Hungary: Integrating Conservation Tillage with the Application of <i>Rhizobium</i> spp., <i>Ensifer</i> spp., <i>Pseudomonas</i> spp., and <i>Bacillus<... by Jana Marjanović, Abdulrahman Maina Zubairu, Sandor Varga, Shokhista Turdalieva, Réka Erika Döbröntey, Mária Ágnes Fodor, Apolka Ujj

“…This ongoing study focuses on evaluating the long-term effects of crop rotation on key agricultural parameters, aiming to optimize practices over time. Statistical analysis (one-way ANOVA) revealed no significant differences across most parameters <i>(p</i> > 0.05), except for total sugar content (<i>p</i> < 0.05), which aligns with expectations given the limited tillage prior to the study. …”
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MALDI-TOF MS experience with the identification of complex microorganisms using two devices in a National Reference Laboratory by Maria Florencia Rocca, Diego Danze, Gastón D´Angiolo, Paula Etcheverry, Claudia Martínez, Mónica Prieto

“…ABSTRACT Matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) methodology has meant a true revolution in clinical microbiology, optimizing diagnosis times through reliable results in a matter of minutes, replacing phenotypic and molecular procedures in several cases. …”
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Cooking for disability: a pilot study on nutritional interventions for mental health support in adults with autism spectrum disorder by Johanna Maria Catharina Blom, Ciro Ruggerini, Franco Caroli, Carla Ferreri, Annalisa Masi, Veronica Rivi, Pierfrancesco Sarti, Mauro Rebecchi, Chiara Arletti

“…Despite these insights, targeted nutritional interventions in adults with severe ASD remain understudied.AimThis pilot study investigated whether a precision, biomarker-guided dietary intervention could improve both behavioral symptoms and underlying biological dysregulations in adults with Level 3 ASD.MethodsSeven adults with severe ASD residing at the ASP Charitas residential facility in Modena (Italy) participated in a 12-month dietary intervention aimed at reducing inflammation, optimizing fatty acid profiles, and supporting metabolic health. …”
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Enhanced Aerosol Containment Performance of a Negative Pressure Hood with an Aerodynamic Cap Design: Multi-Method Validation Using CFD, PAO Particles, and Microbial Testing by Seungcheol Ko, Kisub Sung, Min Jae Oh, Yoonjic Kim, Min Ji Kim, Jung Woo Lee, Yoo Seok Park, Yong Hyun Kim, Ju Young Hong, Joon Sang Lee

“…Healthcare providers performing aerosol-generating procedures (AGPs) face significant infection risks, emphasizing the critical need for effective aerosol containment systems. In this study, we developed and validated a negative pressure chamber enhanced with an innovative aerodynamic cap structure designed to optimize aerosol containment. …”
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Determining Ligand Binding and Specificity Within the β₂-Integrin Family with a Novel Assay Platform by Carla Johanna Sommer-Plüss, Céline Leiggener, Elira Nikci, Riccardo Vincenzo Mancuso, Said Rabbani, Christina Lamers, Daniel Ricklin

“…For this purpose, the major ligand-binding domains (αI) of all four β₂ integrins were recombinantly expressed in both low- and high-affinity states. By optimizing the expression parameters and selecting appropriate purification tags, all αI-domain variants could be produced with high yield and purity. …”
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Evaluating Sugarcane Yield Estimation in Thailand Using Multi-Temporal Sentinel-2 and Landsat Data Together with Machine-Learning Algorithms by Jaturong Som-ard, Savittri Ratanopad Suwanlee, Dusadee Pinasu, Surasak Keawsomsee, Kemin Kasa, Nattawut Seesanhao, Sarawut Ninsawat, Enrico Borgogno-Mondino, Filippo Sarvia

“…Farmers can apply the maps to gain an overview of the yield variability, improving farm management practices and optimizing inputs to increase productivity and sustainability such as fertilizers. …”
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The Characteristics of Chitosan Derived from Lobster Shells and its Effect on Fungi Activity and Water Stability of Lobster Pellets by Muhsinul Ihsan, Ali Harris, Mukminah, Megawati, Nining Purwati, Handa Muliasari, Bayu Priyambodo, Clive Jones, Leo Nankervis

“…Increasing concentration of chitosan increased water stability of pellets up to 1.5% inclusion, while 0.5% optimized Fusarium sp. inhibition. These findings suggest that chitosan from lobster shells can be sustainably utilized to enhance feed quality, reducing fungal contamination and nutrient leaching in aquaculture systems.…”
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Engineering a 3D platform for testis bioengineering: generation and proteomic profiling of decellularized fish testicular scaffolds by Ivana Felipe Rosa, Ivana Felipe Rosa, Ivana Felipe Rosa, Beatriz Marques Souza, Lucas Benites Doretto, Lucas Benites Doretto, Maira da Silva Rodrigues, Caroline Nascimento Barquilha, Matheus Naia Fioretto, Luiz Marcos Frediani Portela, José Carlos Souza Vieira, Luis Antonio Justulin, Pedro de Magalhães Padilha, Changwei Shao, Changwei Shao, Rafael Henrique Nóbrega

“…Further investigations are warranted to optimize hydrogel formulations and assess their capacity to support the in vitro proliferation and differentiation of spermatogonial stem cells (SSCs).…”
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Patient-centered outcomes with subcutaneous immunoglobulin use for infection control in primary and secondary immunodeficiencies: data of a GEIE Spanish Registry by Sandra Martínez Mercader, Victor Garcia-Bustos, Victor Garcia-Bustos, Pedro Moral Moral, Pedro Moral Moral, Carmen Martínez Buenaventura, Elisa Escudero Vergara, María Carmen Montaner Bosch, Héctor Balastegui-Martín, Héctor Balastegui-Martín, Sonia Galindo Maycas, Berta Palací Mur, Marian Escobar Palazón, María Moreno Mulet, Ignacio Campanero Carrasco, Alicia López, Carlos Daniel Hernández Ruiz, Laura Ruiz-López, Rocío Guzmán Guzmán, Rocío Guzmán Guzmán, Marta Dafne Cabañero-Navalon, Marta Dafne Cabañero-Navalon

“…Background and aimSubcutaneous immunoglobulin (SCIg) has emerged as an alternative to intravenous administration for patients with primary (PID) and secondary immunodeficiencies (SID), offering benefits such as fewer systemic adverse reactions and greater patient autonomy. …”
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The impact of mass screening and treatment interventions on malaria incidence and prevalence: a retrospective analysis of a malaria elimination programme in eastern Myanmar, and sy... by Jade D. Rae, Angela Devine, Chanapat Patekkham, Aung Myint Thu, Gilles Delmas, Daniel M. Parker, Richard J. Maude, Jacher Wiladphaingern, Ladda Kajeechiwa, May Myo Thwin, Saw Win Tun, Julie A. Simpson, François H. Nosten

“…While these interventions are important drivers for achieving elimination goals, particularly in high-burden settings, it is important that various factors be considered when determining their suitability and how to optimize implementation.…”
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Rapid Determination of Fatty Acids in Ziziphi Spinosae Semen from Different Origins by Internal Extractive Electrospray Ionization Mass Spectrometry by Peng LIU, Ning WANG, Si-yu XIE, Le-ting WANG, Zhe-hao LIANG, Run-chen LAI, Man-man QIN

“…After the conditions were optimized, methanol was chosen as the extraction solvent, the temperature of the ion transport tube was set at 400 ℃, and the spray voltage was fixed at −5 kV. …”
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Plot‐level satellite imagery can substitute for UAVs in assessing maize phenotypes across multistate field trials by Nikee Shrestha, Anirudha Powadi, Jensina Davis, Timilehin T. Ayanlade, Huyu Liu, Michael C. Tross, Ramesh K. Mathivanan, Jordan Bares, Lina Lopez‐Corona, Jonathan Turkus, Lisa Coffey, Talukder Zaki Jubery, Yufeng Ge, Soumik Sarkar, James C. Schnable, Baskar Ganapathysubramanian, Patrick S. Schnable

“…Summary Accurate early yield estimates at fields and plots offer potential benefits to farmers in optimizing their agronomic practices and breeders in screening thousands of varieties contributing to improving agriculture and food production systems. …”
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Interleukin-15Rα-Sushi-Fc Fusion Protein Co-Hitchhikes Interleukin-15 and Pheophorbide A for Cancer Photoimmunotherapy by Zhe Li, Jiaojiao Xu, Hongzheng Lin, Sheng Yu, Jingwen Sun, Chen Zhang, Sihang Zhang, Tingting Li, Afeng Yang, Wei Lu

“…<b>Conclusions</b>: The enhanced antitumor therapeutic effect demonstrates that the co-hitchhiking delivery strategy, optimizing the pharmacokinetics of both the photosensitizer and IL-15, provides a promising strategy for combinatorial photodynamic and IL-15 immunotherapy.…”
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First-Principles Study on the CO₂ Reduction Reaction (CO₂RR) Performance of h-BN-Based Single-Atom Catalysts Modified with Transition Metals by Xiansheng Yu, Can Zhao, Qiaoyue Chen, Lai Wei, Xucai Zhao, Lili Zhang, Liqian Wu, Yineng Huang

“…In the CO₂RR pathway, Mn@B₋₁N exhibits the lowest limiting potential (<i>U_L</i> = −0.524 V), and its higher d-band center (−0.334 eV), which aligns optimally with the adsorbate orbitals, highlights its excellent catalytic activity. …”
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Methotrexate and Tumor Necrosis Factor Inhibitors Independently Decrease Neutralizing Antibodies after SARS-CoV-2 Vaccination: Updated Results from the SUCCEED Study by Carol A Hitchon, Dawn M. E. Bowdish, Gilles Boire, Paul R. Fortin, Louis Flamand, Vinod Chandran, Roya M. Dayam, Anne-Claude Gingras, Catherine M. Card, Inés Colmegna, Maggie J. Larché, Gilaad G. Kaplan, Luck Lukusa, Jennifer L.F. Lee, Sasha Bernatsky, on behalf of the SUCCEED Investigative Team

“…As SARS-CoV-2 circulation continues, ongoing vigilance regarding optimized vaccination is required.…”
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Somatization symptoms and burnout: a correlational study among emergency nurses by Ningxiang Li, Ningxiang Li, Ningxiang Li, Nan Xie, Nan Xie, Nan Xie, Xiaoli Chen, Xiaoli Chen, Xiaoli Chen, Hao Zhang, Hao Zhang, Hao Zhang, Luying Zhong, Luying Zhong, Luying Zhong, Dongmei Diao, Dongmei Diao, Dongmei Diao, Ling Zhu, Ling Zhu, Ling Zhu, Yue Zhou, Yue Zhou, Yue Zhou

“…To address this issue, healthcare management should consider implementing alternative shift patterns, optimizing workforce allocation, and revising compensation systems to ensure equitable labor distribution. …”
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Beyond the surface of capacity building: a mixed-methods study of the core functions and forms of dissemination and implementation science consultations by Kera N. Swanson, Nicole A. Stadnick, Gregory A. Aarons, Lauren Brookman-Frazee, Isaac Bouchard, Zeying Du, Anna G. Brubaker, Carrie Geremia, Kelli Cain, Lilliana R. Conradi, Marisa Sklar, Clare Viglione, Borsika A. Rabin

“…These results suggest the need for scalable consultation frameworks, improved tracking systems, and tiered training resources to optimize the reach and impact of DIS capacity-building efforts.…”
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