Advancements in Bio-Nanotechnology: Green Synthesis and Emerging Applications of Bio-Nanoparticles by M. D. K. M. Gunasena, G. D. C. P. Galpaya, C. J. Abeygunawardena, D. K. A. Induranga, H. V. V. Priyadarshana, S. S. Millavithanachchi, P. K. G. S. S. Bandara, K. R. Koswattage

“…It highlights the need for further research to optimize synthesis processes, understand mechanisms of action, and expand the scope of their applications. …”
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Interrelationship Between Obstructive Sleep Apnea Syndrome and Small Airway Disease: A Comprehensive Review by Chou-Chin Lan, Chung Lee, Lun-Yu Jao, Yao-Kuang Wu, Kuo-Liang Huang, Wen-Lin Su, Yi-Chih Huang, Chih-Wei Wu, Mei-Chen Yang

“…Addressing shared risk factors and understanding the interplay between these conditions are crucial for optimizing care. This review identifies key knowledge gaps, including the need for precise diagnostic tools and targeted therapies, which are essential for advancing personalized treatment strategies for individuals with obstructive sleep apnea syndrome and small airway disease.…”
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A comprehensive review of additively manufactured biomedical titanium alloys for bone tissue engineering: Biocorrosion, biomechanical, and biological properties by A.H. Noorbakhsh Nezhad, E. Mohammadi Zahrani, S.F. Mousavinasab, A.M. Alfantazi

“…Additively manufactured Ti-based scaffolds manifest a controllable combination of essential properties such as modulated porosity fraction, optimized porous architecture, tuned Young's modulus, and adjustable mechanical properties. …”
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The Effect of Layer Thickness and Nozzle Diameter in Fused Deposition Modelling Printing on the Flexural Strength of Zirconia Ceramic Samples Produced by a Multistage Manufacturing... by Anton Smirnov, Oleg Yanushevich, Natella Krikheli, Yulia Zhukovskaya, Mihail Soloninkin, Petr Naumenko, Nestor Washington Solis Pinargote, Pavel Peretyagin, Sergey Grigoriev, Nikita Nikitin

“…The results obtained make it possible to optimize the considered process of manufacturing ceramic products from ZrO₂ printed using FDM technology from extruded composite filaments.…”
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Simultaneous quantification of 12 water-soluble vitamins in MDCK cell culture media by eco-friendly ion-pairing reagent-free HPLC-UV by Lei Zhou, Mengting Zhang, Huinan Sun, Liyuan Duan, Qingwei Meng

“…This robust, cost-effective platform provides biomanufacturers with a powerful quality control tool for optimizing vitamin supplementation in vaccine production systems, addressing a critical gap in cell culture analytics.…”
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Investigation of biomolecular dynamics by sensitivity-enhanced 1H–2H CPMAS NMR using matrix-free dynamic nuclear polarization by Thomas Biedenbänder, Aryana Rodgers, Mirjam Schröder, Liliya Vugmeyster, Björn Corzilius

“…Here, we present an approach to use DNP-enhanced 2H NMR to study dynamics of selectively deuterated methyl groups in insoluble proteins such as amyloid beta (Aβ) fibrils. We adopted and optimized the matrix-free DNP approach by varying the amount of added polarizing agent as well as the rehydration level of model proteins. …”
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Decoding colorectal cancer lung metastasis: a global research odyssey by Xu Zhang, Xu Zhang, Liping Wang, Tong Fu, Xuchu Duan, Hao Wang, Yuqing Chen, Xiaoyu Liu

“…Future research should focus on optimizing integrated therapeutic approaches and refining clinical management protocols to further improve outcomes for patients with CRC and pulmonary metastases.…”
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Efficient TE-Polarized Mode-Order Converter Based on High-Index-Contrast Polygonal Slot in a Silicon-on-Insulator Waveguide by Lijun Hao, Rulei Xiao, Yuechun Shi, Pan Dai, Yong Zhao, Shengping Liu, Jun Lu, Xiangfei Chen

“…Therefore, when the slot is optimized, we can achieve efficient mode conversions based on the multimode interference. …”
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Co-Cultivations of <i>Beauveria bassiana</i>, <i>Metarhizium anisopliae</i>, and <i>Trichoderma harzianum</i> to Produce Bioactive Compounds for Application in Agriculture by Pauline Flores da Silva, Maicon Sérgio Nascimento dos Santos, Beatriz de Andrade Araújo, Bruno Douglas Kerber, Heloisa Alves Pinto de Oliveira, Jerson Vanderlei Carús Guedes, Marcio Antonio Mazutti, Marcus Vinícius Tres, Giovani Leone Zabot

“…As a way forward, this product demonstrated integrated bioactivities as insecticide and fungicide and can be optimized to substitute chemical pesticides that have negative impacts on the environment.…”
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Adverse events associated with hepatic arterial infusion chemotherapy and its combination therapies in hepatocellular carcinoma: a systematic review by Ying Wu, Zhenpeng Zeng, Shuanggang Chen, Shuanggang Chen, Danyang Zhou, Gangling Tong, Duanming Du

“…These recommendations aim to optimize treatment outcomes while minimizing adverse impacts on patient quality of life.…”
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Surveillance of Antibiotic Prescribing in Intensive Care Units in Poland by Ewa Trejnowska, Aleksander Deptuła, Magda Tarczyńska-Słomian, Piotr Knapik, Miłosz Jankowski, Agnieszka Misiewska-Kaczur, Barbara Tamowicz, Jakub Śmiechowicz, Remigiusz Antończyk, Paul Armatowicz, Wiktor Sułkowski, Grażyna Durek

“…Intensive Care Units (ICUs) represent the heaviest antibiotic burden within hospitals, and sepsis is the second noncardiac cause of mortality in ICUs. Optimizing appropriate antibiotic treatment in the management of the critically ill in ICUs became a major challenge for intensivists. …”
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Engineering Pichia pastoris for the efficient production of the high-value steroid intermediate 15α-OH-D-ethylgonendione by Yu-Long Zeng, Yang-Yang Li, Bei-Feng-Chu Zheng, Dong-Qi Xie, Sheng-Qiang Tong, Yuan Yuan, Ya-Jun Wang, Bin Xue, Xiao-Guang Liu

“…Shake-flask cultivation was performed to optimize fermentation parameters and assess the potential of the engineered P. pastoris strains for 15α-OH-DE production. …”
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Customizable metamaterial design for desired strain-dependent Poisson’s ratio using constrained generative inverse design network by Sukheon Kang, Hyunggwi Song, Hyun Seok Kang, Byeong-Soo Bae, Seunghwa Ryu

“…A deep neural network (DNN) is then trained to map input geometric parameters to these principal components, with the architecture optimized using grid search. The CGIDN facilitates the inverse design process by recommending geometric parameters for unit cell designs that match specified target Poisson’s ratio-strain curves. …”
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Virtual reality and mixed reality in the assessment of spatial memory by Sara Garcia-Navarra, Lucia Solares, Marta Mendez

“…Standardization, accessibility, and the creation of adaptive assessment for clinical populations will be crucial for optimizing the use of digital technologies in spatial memory research.…”
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Non-classical pulmonary exacerbation in cystic fibrosis revealing ALK-Translocated lung cancer: A case report by Mohamad Hadhud, Johnathan Arnon, Anat Hershko-Moshe, Adi Hollander, Noa Hurvitz-Lehmann, Assaf Potruch, Henny Azmanov, Rottem Kuint, Nurith Hiller, Elie Picard, Naama Sebbag-Sznajder, Shira Leebhoff, Michael Wilschanski, Myriam Grunewald, Liron Birimberg-Schwartz, Malena Cohen-Cymberknoh

“…Care for pwCF with lung cancer requires a unique multi-disciplinary approach to optimize their complex multifactorial treatment.…”
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Precise multi-factor immediate implant placement decision models based on machine learning by Guanqi Liu, Shudan Deng, Runzhong Liu, Yuanxiang Liu, Quan Liu, Shiyu Wu, Zhuofan Chen, Runheng Liu

“…This research is of significant reference value for optimizing clinical decision-making, improving the success rate of immediate implant placement, and enhancing the efficiency of doctor-patient communication. …”
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Capture of geogenic pollutants through Borophene B36: In silico analysis from a DFT approach. by Noé Brígido-Salvador, Luz Palomino-Asencio, Rafael Catarino-Centeno, Pricila Betbirai Romero-Vázquez, Laura Gabriela Elvir-Padilla, Erwin García-Hernández

“…This work investigates the interaction mechanisms between geogenic (arsenic and fluoride) pollutants and the B36 nanocluster using density functional theory (DFT). Structural optimizations and energetic analyses reveal strong chemisorption for both fluoride and arsenic in the gas phase, with adsorption energies of −5.38 eV and −2.83 eV, respectively, and short binding distances of 1.40 Å (fluoride) and 1.45 Å (arsenic). …”
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Adaptive control strategies for button motor actuated insect scale flapping wing MAV mechanisms by Spoorthi Singh, Meet Hitesh Jain, Kanishk Kaushal, Mohammad Zuber, Ernnie Illyani Basri, Kamarul Arifin Ahmad, Sharul Sham Dol, Vishnu G. Nair

“…Additionally, an AI-based disturbance observer is implemented to enhance stability and optimize power efficiency by compensating for environmental disturbances. …”
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Correlation and Comparative Evaluation of MOCART and MOCART 2.0 for Assessing Cartilage Repair by Felix Conrad Oettl, Louis Leuthard, Moritz Brunner, Vincent A. Stadelmann, Stefan Preiss, Michael Leunig, Gian M. Salzmann, Jakob Hax

“…<i>Background and Objectives</i>: Chondral and osteochondral lesions can lead to osteoarthritis if untreated, making accurate assessment of cartilage repair outcomes essential for optimizing treatment strategies. The objective of this study was to compare MOCART and MOCART 2.0 and to evaluate the clinical utility of both across different surgical cartilage repair techniques and various time points. …”
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Molecular Dynamics Simulation of Lipid Nanoparticles Encapsulating mRNA by Zhigang Zhang, Dazhi Cheng, Wenqin Luo, Donling Hu, Tiantian Yang, Kaixuan Hu, Li Liang, Wei Liu, Jianping Hu

“…These findings provide a scientific basis for further designing and optimizing LNP components to enhance the efficacy of mRNA vaccine encapsulation.…”
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