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Heterogeneity Assessment of Breast Cancer Tumor Microenvironment: Multiparametric Quantitative Analysis with DCE-MRI and Discovery of Radiomics Biomarkers
Published 2025-07-01“…Future advancements demand multicenter data harmonization, radiogenomics integration, and digital twin technology to optimize personalized therapeutic navigation systems. …”
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Deep Learning-Based Sound Source Localization: A Review
Published 2025-07-01“…Future research should prioritize physics-informed modeling to embed acoustic propagation mechanisms, unsupervised domain adaptation to reduce reliance on labeled data, and sensor-algorithm co-design to optimize hardware-software synergy. These directions aim to propel SSL toward intelligent systems characterized by high precision, strong robustness, and low power consumption. …”
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Economic Peaks and Value-at-Risk Analysis: A Novel Approach Using the Laplace Distribution for House Prices
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Cutaneous Changes Beyond Psoriasis: The Impact of Biologic Therapies on Angiomas and Solar Lentigines
Published 2025-03-01“…Statistical analyses evaluated associations among biologic therapy classes, systemic inflammation, and cutaneous lesion development. …”
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The impact of pH value on the transfer and release dynamics of doxorubicin facilitated by carbon nanotubes within the capillary network surrounding cancerous tumors through molecul...
Published 2024-10-01“…This work concluded that MD simulations greatly enhanced the progress of pH-responsive CNT-based drug delivery systems. By offering comprehensive understanding of their behavior in acidic tumor environments, these simulations optimized these systems for targeted cancer treatment.…”
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Curcumin, EGCG and apigenin in cervical cancer: mechanistic insights and therapeutic potential
Published 2025-07-01“…While bioavailability and systemic stability hinder clinical translation, advancements in nanotechnology and targeted delivery systems offer promising solutions. …”
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43408
A review on aluminum alloys produced by wire arc additive manufacturing (WAAM): Applications, benefits, challenges and future trends
Published 2024-11-01“…In the following section, the methods used to improve mechanical properties and optimize the microstructure are examined in detail. …”
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The Multifactorial Pathogenesis of Endometriosis: A Narrative Review Integrating Hormonal, Immune, and Microbiome Aspects
Published 2025-04-01“…Recent evidence suggests that the gut microbiota significantly influence immune responses, estrogen metabolism, and systemic inflammation, potentially contributing to EM progression. …”
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Carbon footprint reduction associated with a surgical outreach clinic
Published 2021-04-01“…Abstract Background Healthcare systems generate substantial carbon footprints that may be targeted to decrease greenhouse gas emissions. …”
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Unobstructive and safe-to-wear watt-level wireless charger
Published 2024-11-01“…Abstract A wearable microgrid that centralizes and distributes harvested energy across different body regions can optimize power utilization and reduce overall battery weight. …”
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Determinants of myocardial fibrosis in patients with immune-mediated inflammatory diseases
Published 2025-06-01“…IMIDs included rheumatoid arthritis, systemic lupus erythematosus, systemic sclerosis (SSc), ankylosing spondylitis, psoriatic arthritis and vasculitis. …”
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ELSMOR – towards European Licensing of Small Modular Reactors: Methodology recommendations for light-water small modular reactors safety assessment [version 2; peer review: 1 appro...
Published 2024-10-01“…Providing a comprehensive compliance framework that regulators can adopt and operate, the licensing process of such SMRs could be optimized, helping their deployment. In this prospect, as a result of ELSMOR’s work, this article gives an overview of the specific issues that LW-SMRs may bring about in the different domains of nuclear safety, in terms of: • Methodological standpoints: safety goals, safety requirements, safety principles (defence-in-depth implementation); • Main safety functions of reactivity control, decay heat removal and confinement management; • Severe accident management; • Other safety issues particular to SMRs: use of shared systems; performing of multi-unit probabilistic safety assessment (PSA); spent fuel management, transport and disposal management. …”
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Oridonin: A natural terpenoid having the potential to modulate apoptosis and survival signaling in cancer
Published 2025-02-01“…Its derivatives and novel delivery systems offer promising avenues for overcoming drug resistance and optimizing its therapeutic efficacy. …”
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AI and Interventional Radiology: A Narrative Review of Reviews on Opportunities, Challenges, and Future Directions
Published 2025-04-01“…Robotics and automation in IR are advancing, though full autonomy in AI-guided systems has not been achieved. Despite these advancements, the integration of AI in IR is complex, involving imaging systems, robotics, and other technologies. …”
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Electrospun Polycaprolactone–Gelatin Fibrils Enabled 3D Hydrogel Microcapsules for Biomedical Applications
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