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18661
Comparative analysis of CDR3 length-dependent patterns in VHHs
Published 2025-08-01“…Notably, species-specific differences were apparent, with Alpaca and Llama VHHs showing more pronounced CDR3 length-dependent patterns than those from Bactrians.DiscussionThese findings highlight the significant impact of CDR3 length on VHH sequence, structure, and antigen interaction characteristics, providing valuable insights for VHH engineering, synthetic library design, and the development of therapeutic nanobodies optimized for targeting diverse epitopes.…”
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18662
Application of Membrane Capacitive Deionization as Pretreatment Strategy for Enhancing Salinity Gradient Power Generation
Published 2025-02-01“…However, to fully capitalize on the benefits of MCDI pretreatment, it is recommended that further process optimization be conducted.…”
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18663
Accelerated design of high-strength refractory multi-principal element alloys from first-principles calculations
Published 2025-05-01“…To rapidly develop high-strength refractory multi-principal element alloys (RMPEAs), we systematically calculate elastic moduli and mechanical properties for a series of body-centered-cubic (bcc) RMPEAs using the first-principles method. By analyzing equiatomic V33Nb33Mo34 and V25Nb25Mo25X25 (X = Al, Ti, Zr, Hf, V, Nb, Ta, Cr, Mo, and W) bcc RMPEAs, we discover that the product of shear modulus (G) and electronegativity difference (δχ), i.e., G × δχ, accurately predicts yield strength (σy). …”
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18664
Effect of transcranial direct current stimulation combined with speech and language therapy in post ischemic stroke aphasia: A systematic review
Published 2025-09-01“…However, inconsistencies in outcomes and short-term follow-up effects highlight the need for further research to optimize and standardize treatment protocols.…”
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18665
Machine Learning-Enhanced Discrimination of Gamma-Ray and Hadron Events Using Temporal Features: An ASTRI Mini-Array Analysis
Published 2025-04-01“…Our methodology employs a Random Forest classifier with optimized hyperparameters, trained on a balanced dataset of gamma and hadron events. …”
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18666
Isolation, Characterization, and Preliminary Application of Staphylococcal Bacteriophages in Sichuan <i>Paocai</i> Fermentation
Published 2025-05-01“…Additionally, notable differences in color and flavor were observed between the two groups of <i>paocai</i> during the fermentation process. …”
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18667
Predicting a clinically narrow pelvis using neural network data analysis
Published 2023-05-01“…The use of neural network analysis of clinical data obtained on the eve of childbirth allows to predict СNP development at sufficient degree of accuracy (98.0 %), which, in the future, after being introduced into clinical practice, will optimize a choice of delivery method in patients at risk (anatomically narrow pelvis, large fetus), reduce emergency caesarean sections and improve birth outcomes.…”
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18668
Numerical and Experimental Study of a Hydrodynamic Analysis of the Periodical Fluctuation of Bio-Inspired Banded Fins
Published 2025-02-01“…Furthermore, we analyze how varying angle of attack or optimizing front/rear edge shapes can effectively enhance hydrodynamic performance.…”
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18669
Spatial Matching Relationship between the Accessibility of Elderly Health and Recreation Facilities and the Distribution of Elderly Population: A Case Study of Sichuan Province
Published 2025-05-01“…Subsequently, the influencing factors and driving mechanisms of the matching relationship were analyzed using a geographical detector; the rationality of the layout of regional elderly health and recreation facilities was also analyzed, providing ideas for exploring and optimizing social old-age care strategies in the new era. …”
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18670
Nutrient Solution Selection Modulates Growth Patterns and Leaf Elemental Accumulation in Alfalfa (<i>Medicago sativa</i>) Grown
Published 2025-04-01“…The findings provide empirical evidence for optimizing alfalfa cultivation in a nitrogen-deficient soil-based mix substrate through nutrient solution selection.…”
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18671
PENGARUH AKTIVITAS MENANYA BERBASIS MASALAH DENGAN METODE SAINTIFIK TERHADAP PROSES KOGNITIF SISWA
Published 2020-11-01“…From 353 total population, the sample was taken using simple random sampling technique which resulted in 73 students who were then divided into two classes. The data collection method used was content and empirical validated essay test. …”
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18672
Fabrication-Tolerant Single-Transverse-Mode Supersymmetric Laser Arrays
Published 2025-01-01“…Two independent superpartners are introduced on both sides of the main array, with one coupling and eliminating the higher-order odd symmetry supermodes, and the other coupling and eliminating the higher-order even symmetry supermodes in the main array, enabling more efficient coupling of higher-order transverse modes into the lossy superpartners, which leads to the increased loss of high-order supermodes. RDS design method is used to improve the single-transverse-mode characteristics with fabrication tolerance, which considers the fabrication error in ridge waveguide width during the optimization process. …”
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18673
Studi Model Bisnis Eksisting dalam Implementasi Layanan Lumpur Tinja Terjadwal (LLTT) di Bawah Satuan Kerja (Studi kasus: Kota Bekasi dan Kota Makassar) dan BUMD (Studi kasus: Kota...
Published 2021-11-01“…This study aims to identify and evaluate the business model that implements the LLTT method that operate under Local’s Work Units (UPTD) and under Regional/Locals’s Owned Enterprises (BUMD) with the method of observation, literature study, and interviews. …”
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18674
Machine learning algorithms to predict stroke in China based on causal inference of time series analysis
Published 2025-05-01“…Setting CHARLS adopts a multi-stage probability sampling method, covering samples from 28 provinces, and collects data every two years through computer-aided personal interviews (CAPI). …”
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18675
Deciphering the role of miRNA-mRNA interactions in cerebral vasospasm post intracranial hemorrhage
Published 2025-02-01“…By employing the degree scores method for each gene, we identified the top 10 genes and developed a protein-protein interaction (PPI) network. …”
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18676
Unraveling the discrepancies between Eulerian and Lagrangian moisture tracking models in monsoon- and westerly-dominated basins of the Tibetan Plateau
Published 2024-09-01“…For moisture tracking over the TP, we recommend using high-resolution forcing datasets, prioritizing temporal resolution over spatial resolution for WAM2layers, while for FLEXPART-WaterSip, we suggest applying bias corrections to optimize the filtering of precipitation particles and adjust evaporation estimates.…”
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18677
Impact of the absence of opioid anesthesia on postoperative outcome indicators: a systematic review and meta-analysis
Published 2025-08-01“…OFA is expected to serve as a safe and effective anesthesia strategy to optimize the perioperative outcomes of patients.…”
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18678
Study on the growth characteristics of Pinus yunnanensis seedlings based on hormonal regulation and chlorophyll metabolism
Published 2025-02-01“…These findings can provide valuable references for cultivating high-quality seedlings, optimizing seed source selection, and improving afforestation techniques.…”
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18679
Performance Improvement of TiO<sub>2</sub> Ultraviolet Photodetectors by Using Atomic Layer Deposited Al<sub>2</sub>O<sub>3</sub> Passivation Layer
Published 2024-11-01“…To reduce the processing time and enhance light absorption, a hydrothermal method was used to grow a relatively thick TiO<sub>2</sub>-NR-containng working electrode. …”
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18680
Propagation Characteristics of Multi-Cluster Hydraulic Fracturing in Shale Reservoirs with Natural Fractures
Published 2025-04-01“…Hydraulic fracturing of gas and oil reservoirs is the primary stimulation method for enhancing production in the field of petroleum engineering. …”
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