Epidemiology of pulmonary embolism in China, 2021: a nationwide hospital-based studyResearch in context by Kaiyuan Zhen, Yuzhi Tao, Lei Xia, Shengfeng Wang, Qian Gao, Dingyi Wang, Zhaofei Chen, Xianglong Meng, Yuting Kang, Guohui Fan, Zhu Zhang, Peiran Yang, Jixiang Liu, Yu Zhang, Chaozeng Si, Wei Wang, Jun Wan, Yuanhua Yang, Zhihong Liu, Yingqun Ji, Juhong Shi, Qun Yi, Guochao Shi, Yutao Guo, Nuofu Zhang, Zhaozhong Cheng, Ling Zhu, Zhe Cheng, Xianbo Zuo, Wanmu Xie, Qiang Huang, Shuai Zhang, Lanxia Gan, Bing Liu, Simiao Chen, Cunbo Jia, Chen Wang, Zhenguo Zhai

“…We then calculated the incidence and mortality rates in different conditions of VTE prevention and management system construction. …”
Get full text

Role of Post-Operative Rehabilitation in TM Joint Arthritis: Functional Outcomes of Interposition Trapeziectomy vs. Prosthesis by Camillo Fulchignoni, Silvia Pietramala, Leopoldo Arioli, Emanuele Gerace, Domenico De Mauro, Giulia Frittella, Elisa Di Dio, Mirko Grauso, Gianfranco Merendi, Lorenzo Rocchi

“…However, the role of post-operative rehabilitation in optimizing outcomes for these procedures remains underexplored. …”
Get full text

Kinesiophobia and associated factors among patients after cardiac surgery under cardiopulmonary bypass: a cross-sectional study by Min You, Min You, Qianqian Mou, Qianqian Mou, Xiaotao Cao, Xiaotao Cao, Meng Luo, Meng Luo, Yi Song, Yi Song, Qingqing Li, Qingqing Li, Huiyun Hu, Huiyun Hu, Jianping Song

“…Nonetheless, few studies have explored this phenomenon in patients following cardiac surgery under cardiopulmonary bypass.ObjectivesThe primary objective of this study was to investigate the prevalence of kinesiophobia and its contributing factors in patients after cardiac surgery under cardiopulmonary bypass, to inform the development of targeted intervention strategies to address kinesiophobia, enhance patient motivation and adherence to early activities, and optimize postoperative rehabilitation outcomes.MethodsA cross-sectional survey was conducted, assessing patients via questionnaires, including the Tampa Scale for Kinesiophobia Heart, Exercise Self-Efficacy Scale, D Personality Scale-14, Pain Catastrophizing Scale, and Family Care Index Questionnaire. …”
Get full text

The evolution of three-dimensional knee kinematics after ACL reconstruction within one year by Lingchuang Kong, Huahao Lai, Xiaolong Zeng, Peng Gao, Peng Gao, Wenhao Liang, Qi Gao, Qi Gao, Zhiyuan Kong, Wu Wu, Xiaona Wu, Tao Zhang

“…IntroductionThis study aims to explore the dynamic changes in the six degrees of freedom (6DOF) kinematics of the knee joint in patients within one year after anterior cruciate ligament reconstruction (ACLR), combined with clinical scoring systems to analyze functional recovery characteristics, providing scientific evidence for optimizing postoperative rehabilitation strategies.MethodsThe study enrolled 49 patients followed up at 3 months postoperatively, 33 patients at 6 months, and 35 patients at 12 months. …”
Get full text

The impact of COVID-19 on thyroid function and psychological state of Graves’ disease: a one-year prospective study by Lujia Xu, Jianbo Zhang, Jianbo Zhang, Riping Cong, Yujian Zhang, Xuenan Song, Wei Wang, Yingli Diao, Haijiao Liu, Kuanxiao Tang

“…The FT3/FT4 ratio guides (antithyroid drugs) ATDs optimization, while psychological intervention effectively mitigates anxiety and depression in GDC patients.…”
Get full text

Comparing palliation strategies for single-ventricle anatomy with transposed great arteries and systemic outflow obstructionCentral MessagePerspective by Alyssa B. Kalustian, MD, Zachary A. Spigel, MD, Christopher E. Greenleaf, MD, Tam T. Doan, MD, Alejandra I. Chavez, MD, Iki Adachi, MD, Jeffrey S. Heinle, MD, Ziyad M. Binsalamah, MD

“…There were no significant differences in overall survival, Fontan completion, reintervention-free survival in the first interstage period, pulmonary artery reintervention-free survival, long-term systemic valve competency, or ventricular dysfunction. …”
Get full text

EFFICIENCY OF DYNAMIC ELECTRONEUROSTIMULATION IN KNEE OSTEOARTHRITIS: RESULTS OF A MULTICENTER RANDOMIZED STUDY by O. M. Lesnyak, E. Yu. Kadochnikova, L. I. Alekseeva, I. G. Dydykina, O. B. Ershova, E. M. Zaitseva, T. A. Korotkova, T. A. Popova, M. L. Sukhareva, E. A. Taskina, V. N. Khodyrev, E. P. Sharapova, A. G. Solodovnikov, A. A. Vlasov

“…Dynamic electroneurostimulation (DENS) is a type of percutaneous electroneurostimulation with a differentiation approach to choosing exposure areas and to optimizing electrocutaneous therapeutic action on the reflexogenic areas and acupuncture points for analgesia and for the treatment of functional disorders.Objective: to study the clinical efficiency and safety of therapy using a DiaDENS-PC apparatus in the treatment of knee osteoarthritis (OA).Subjects and methods. …”
Get full text

Prediction of joint deformity after MIPPO with double reverse traction repositor based on Hounsfield units derived from CT scans by Guimiao Li, Kejia Shang, Shengnan Zhang, Zhongzheng Wang, Yanjiang Yang, Chunxu Fu, Chen Feng, Di Zhang, Yingze Zhang

“…We analyzed the relationship between Bone Mineral Density(BMD), knee alignment, PTOA grading, and joint function. Differences in BMD and knee alignment were compared between patients with HKA < 177° (varus group) and those with HKA ≥ 177° (non-varus group). …”
Get full text

A case-control study on Chlamydia psittaci pneumonia and legionella pneumonia by Ying Gao, Yuan-jie Lin, Wen-long Zhang, Jian-ming Ni, Shu-guang Han, Liang Bao

“…This allows for the optimization of antibiotic choices and the reduction of unnecessary multidrug combinations, which can improve prognosis and reduce the risk of drug resistance.…”
Get full text

Linguistic Markers of Pain Communication on X (Formerly Twitter) in US States With High and Low Opioid Mortality: Machine Learning and Semantic Network Analysis by ShinYe Kim, Winson Fu Zun Yang, Zishan Jiwani, Emily Hamm, Shreya Singh

“…Semantic network analysis revealed denser discourse in HDS (density=0.28) focused on distress and barriers to care, while LDS discourse emphasized recovery and optimism. ConclusionsOur findings demonstrated that linguistic markers in publicly shared pain-related discourse show distinct and predictable differences across regions with varying opioid mortality risks. …”
Get full text

Enhancing Immersion in Virtual Reality–Based Advanced Life Support Training: Randomized Controlled Trial by Dilek Kitapcioglu, Mehmet Emin Aksoy, Arun Ekin Ozkan, Tuba Usseli, Dilan Cabuk Colak, Tugrul Torun

“…Further research should explore ways to optimize AI’s role in education through VR. …”
Get full text

RATIONAL SUPPORTIVE THERAPY FOR CHEMOTHERAPY INDUCED ANEMIA: A PHARMACO-ECONOMIC ANALYSIS OF ERYTHROPOIETIN THERAPY IN CANCER PATIENTS IN RUSSIAN FEDERATION by V. B. Larionova, I. S. Krysanov, A. V. Snegovoy, P. A. Zeinalova, V. S. Krysanova, V. Yu. Ermakova

“…Recombinant forms of human erythropoietin and intravenous forms of iron preparations should be the most popular correction methods in everyday practice.The high cost of complex anemia therapy and the social significance of oncological diseases necessitate a pharmaco-economic analysis of registered in Russia erythropoietin preparations and the optimization of existing anemia treatment regimens in cancer patients in order to reduce the expenditures of the health budget. …”
Get full text

Comprehensive analysis of 1103 infants referred to a single center due to positive newborn screening test for phenylketonuria by Ayça Burcu Kahraman, Kısmet Çıkı, Begüm Poşul, Mustafa Güvercin, Yılmaz Yıldız, Ali Dursun, Serap Sivri, Turgay Coşkun, Ayşegül Tokatlı

“…This study highlights significant regional differences within Türkiye regarding DBS collection, result reporting, and age at admission. …”
Get full text

Efficacy and safety comparison of CAR-T and blinatumomab immunotherapy as bridge-to-transplant strategies in relapsed/refractory B cell acute lymphoblastic leukemia by Wenyue Cao, Ningwen Li, Gaoxiang Wang, Hao Xu, Yang Yang, Jue Wang, Jinhuan Xu, Yun Li, Yicheng Zhang, Yang Cao, Na Wang

“…Further studies are needed to optimize these treatment strategies.…”
Get full text

Disparities in Rotator Cuff Tear Progression Definitions and Rates by Mason J. Garcia, BS, Daniela Caro, MD, Maria Velasquez Hammerle, MD, Juan B. Villarreal, MD, Joseph P. DeAngelis, MD, MBA, FAOA, FAAOS, Arun J. Ramappa, MD, Ara Nazarian, PhD

“…For FT tears, the progression rate was 54.9% ± 18.6% at a follow-up time of 3.0 ± 2.0 years, with 8 definitions for tear enlargement. A significant difference (p < 0.0001) was found between the progression rates of PT and FT tears. …”
Get full text

Development and validation of a 16-gene T-cell- related prognostic model in non-small cell lung cancer by Anbing Zhang, Anbing Zhang, Huang Ting, Huang Ting, Jun Ma, Jun Ma, Xiuqiong Xia, Xiaoli Lao, Xiaoli Lao, Siqi Li, Jianping Liang, Jianping Liang

“…BackgroundNon-small cell lung cancer (NSCLC) exhibits variable T-cell responses, influencing prognosis and outcomes.MethodsWe analyzed 1,027 NSCLC and 108 non-cancerous samples from TCGA using ssGSEA, WGCNA, and differential expression analysis to identify T-cell-related subtypes. …”
Get full text

NG2 MOLECULE EXPRESSION IN ACUTE LYMPHOBLASTIC LEUKEMIA B CELLS: A FLOW-CYTOMETRIC MARKER FOR THE RAPID IDENTIFICATION OF KMT2A GENE REARRANGEMENTS by Maria Laura Bisegna, Nadia Peragine, Loredana Elia, Mabel Matarazzo, Maria Laura Milani, Stefania Intoppa, Mariangela Di Trani, Francesco Malfona, Maurizio Martelli, Maria Stefania De Propris

“…Materials and Methods: We evaluated 88 NG2+ B-ALL cases identified with a NG2 positivity threshold >10%, from a cohort of 1382 newly diagnosed B-ALLs referred to the Division of Hematology of ‘Sapienza’ University of Rome.                                                       …”
Get full text

Microbial and clinical disparities in pneumonia: insights from metagenomic next-generation sequencing in patients with community-acquired and severe pneumonia by Wang Luo, Shuhua Zhang, Jinhuan Sun, Jinhuan Sun, Jianhui Xu, Weihua Huang, Ruiqing Hao, Zhao Ou, Zhao Ou, Ziyang Wen, Ziyang Wen, Daiwei Wang, Daiwei Wang, Guanhua Xiao, Hangming Dong

“…Beta diversity analysis demonstrated significant differences in microbial community composition between CAP and SP groups (p = 0.001), though alpha diversity metrics showed no significant differences. …”
Get full text

Causal inference study of PRRSV-MLV vaccine dosing effects on wean-to-finish performance during outbreaks by Swaminathan Jayaraman, Tyler Bauman, Amy Maschhoff, Caleb Shull, Peng Li, Edison Magalhaes, Giovani Trevisan, Daniel C. L. Linhares, Chunlin Li, Gustavo S. Silva

“…This study demonstrates the value of causal inference methods in analyzing real-world vaccination outcomes and provides evidence-based guidance for optimizing PRRSV vaccination protocols in commercial swine production.…”
Get full text

Polymorphism of TNF gene in acute coronary syndrome patients: data from the registries ORACLE I and ORACLE II by V. A. Brazhnik, L. О. Minushkina, A. О. Averkova, Е. A. Zubova, A. A. Rogozhina, М. A. Evdokimova, A. S. Galyavich, S. N. Tereshchenko, N. A. Koziolova, М. G. Glezer, А. V. Jagoda, О. I. Boeva, Е. V. Khoroletz, Е. А. Karmanchikova, V. O. Konstantinov, G. I. Speshilov, Е. N. Dankovtseva, D. А. Zateishchikov

“…To analyze possible association of the risk of adverse outcomes development in patients post acute coronary episode (ACS), with the polymorphism of gene TNF. Material and methods. To the study, patients included, that were under observation in 2 registry studies ORACLE I and II (Exacerbation of coronary heart disease: logic-probability ways of course prediction and treatment optimization). …”
Get full text