Primary Cell Cultures in Neurobiology: Optimized Protocol for Culture of Mouse Fetal Hindbrain Neurons by Hadrien Glibert, Laure Bridoux, Maëlle Palate, Coralie Piget, Marie-Thérèse Ahn, Roberta Gualdani, Ana Domínguez-Bajo, Frédéric Clotman, Filippo M. Rijli, Françoise Gofflot

“…Importantly, considerable differences exist in neuronal cell populations and in glial cell contribution between different brain regions. …”
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Optimization and Evaluation of Conditions for Orthotopic Nude Mouse Models of Human Liver Tumor Cells by MENG Yu, LIANG Dongli, ZHENG Linlin, ZHOU Yuanyuan, WANG Zhaoxia

“…Objective The study aims to optimize the conditions for constructing orthotopic nude mouse models of liver cancer by injecting human liver tumor cell lines and to explore appropriate timings for drug administration. …”
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Parameter optimization of the notched blade spiral fertilizer discharger for pineapple orchards based on DEM by Guoqiang Dun, Guoqiang Dun, Quanbao Sheng, Xinxin Ji, Hailiang Li, Chunyu Ma, Xinming Li, Haitian Sun, Luhan Wang, Chao Ma, Zhenzhen Yu, Hongxuan Wang

“…The discrete element method is used to simulate the fertilizer-discharging process. …”
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Heuristic thermal sensor allocation methods for overheating detection of real microprocessors by Xin Li, Xueting Wei, Wei Zhou

“…On this basis, a heuristic method based on genetic algorithm is proposed to find a near‐optimal thermal sensor allocation solution, which can make overheating detection probability significantly improved with a greatly reduced execution time. …”
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A Method for Evaluating the Digital Precision of Induction Logging Tools by ZHAO Yanwei, LIANG Xiaobing, SUN Xuekai, CHEN Wen, LIU Yue, JIANG Liming, ZHU Ruiming

“…Effectiveness of the proposed method is verified by inspecting the consistency between the equivalent apparent conductivity of the "zero" signal and the theoretical outcomes of "ADC conductivity scales". …”
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Solving Bilevel Multiobjective Programming Problem by Elite Quantum Behaved Particle Swarm Optimization by Tao Zhang, Tiesong Hu, Jia-wei Chen, Zhongping Wan, Xuning Guo

“…Finally, we use eight different test problems to measure and evaluate the proposed algorithm, including low dimension and high dimension BLMPPs, as well as attempt to solve the BLMPPs whose theoretical Pareto optimal front is not known. …”
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Multi-Level Thresholding Color Image Segmentation Using Modified Gray Wolf Optimizer by Pei Hu, Yibo Han, Zheng Zhang

“…To acquire the optimal thresholds at different levels, we modify the GWO (MGWO) in terms of leader selection, position update, and mutation. …”
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Optimization of dynamic parameters of straddle monorail vehicle to improve pantograph-catenary contact quality by ZHANG Yuejun, YANG Zhen, DU Zixue, WEN Xiaoxia, XU Zhouzhou

“…The results show that the rigidness of the running tires and the guide tires has a great influence on the pantograph-catenary contact quality , and the standard deviation of the contact force decreases to a certain degree at different speed after parameter optimization. The abrasion problem of pantograph sliding block of straddle monorail vehicle can be improved by optimizing the radial rigidness of tires.…”
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A Method of Productivity Prediction for Multi-Fractured Horizontal Well by YANG Fan, GAO Yanwu, SHAO Guanghui, LIU Jieli, XU Rui, ZHOU Jufeng

“…After large-scale volume fracturing by classification and clustering, there is a large difference in production. The factors affecting production capacity are not clear, which makes it difficult to evaluate the production capacity of horizontal wells. …”
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The rock cutting simulation of heterogeneous granite using FDEM method by Weiji Liu, Hongxing Deng, Xiaohua Zhu, Yanxin Lv, Yunxu Luo

“…However, the traditional mechanical rock breaking is still the mainstream rock-breaking method. A detailed understanding of the rock cutting mechanism is essential to achieve high efficiency in rock breaking and to optimize the cutting parameters. …”
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REFLEX—A novel method for the rapid estimation of flood extent by Mauro Arcorace, Andrea Libertino, Lorenzo Alfieri, Simone Gabellani, Alessia Matanò, Alessandro Masoero, Valerio Basso, Giorgio Boni

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Risk Analysis and Route Optimization of Dangerous Goods Transportation Based on the Empirical Path Set by Haixing Wang, Qianqian Liang

“…Based on the empirical path set generated from the track data of dangerous goods vehicles, we present a new method for the risk analysis and path optimization of dangerous goods transportation. …”
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A Lightweight Citrus Object Detection Method in Complex Environments by Qiurong Lv, Fuchun Sun, Yuechao Bian, Haorong Wu, Xiaoxiao Li, Xin Li, Jie Zhou

“…Aiming at the limitations of current citrus detection methods in complex orchard environments, especially the problems of poor model adaptability and high computational complexity under different lighting, multiple occlusions, and dense fruit conditions, this study proposes an improved citrus detection model, YOLO-PBGM, based on You Only Look Once v7 (YOLOv7). …”
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Optimization of bioactive compounds extraction from olive pomace by microwave hydro diffusion and gravity by Vanessa Sabrina Fagundes Batista, Gabriel dos Santos Souza, Débora Piovesan de Moraes, Daniele Freitas Ferreira, Juliano Smanioto Barin, Renius de Oliveira Mello, Cláudia Severo Da Rosa

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Study on optimization strategy for hybrid underlay/overlay spectrum sharing based on queuing model by Jian-ping LIU, Shun-fu JIN, Bao-shuai WANG

“…In order to improve the licensed spectrum utilization in cognitive radio networks,and provide higher experience quality to system users,the optimizing strategies of the hybrid underlay/overlay spectrum sharing mode was studied.For secondary users,a queuing model with service time following two phase order exponential distribution was constructed,and a method to obtain the steady state distribution was presented for the system model.Based on reward-cost structure,individual optimization strategy with observable case and the Nash equilibrium strategy with unobservable case were discussed.With purpose of optimal social benefit and maximal spectrum incomes,the pricing policies for secondary users to use licensed spectrum were formulated.Using the system experiment,the relations among the different optimal strategies were investigated,and the rationality of the price mechanism was verified.By contrasting the optimal social benefits gained by hybrid underlay/overlay spectrum sharing mode，overlay spectrum sharing mode and underlay spectrum sharing mode,it is further shown that the social optimization strategy of hybrid overlay/underlay sharing mode is more effective and stable to fully use the spectrum resource.…”
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Research and Application of Optimization Technology for High-Efficiency Fracturing and Packing Parameters of Unconsolidated Sandstone by Liwei Sun

“…The fracturing and filling technology is expected to meet the dual needs of production stimulation and sand control of unconsolidated sandstone reservoirs, but there is no clear guiding method for the optimization of construction parameters, which hinders its efficient development. …”
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Light-Weighting of Planetary Gearbox Based on Multi-Strategy Optimization Sparrow Search Algorithm by Shuting Lin, Zhirong Zhang, Yinghao Ma, Hua Li

“…During the planetary gearbox design process, the issue of light-weighting has been studied using various methods. To get better results from light-weighting, it is necessary for new methods to be considered to deal with this problem. …”
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An Optimized NGS Workflow Defines Genetically Based Prognostic Categories for Patients with Uveal Melanoma by Michele Massimino, Elena Tirrò, Stefania Stella, Cristina Tomarchio, Sebastiano Di Bella, Silvia Rita Vitale, Chiara Conti, Marialuisa Puglisi, Rosa Maria Di Crescenzo, Silvia Varricchio, Francesco Merolla, Giuseppe Broggi, Federica Martorana, Alice Turdo, Miriam Gaggianesi, Livia Manzella, Andrea Russo, Giorgio Stassi, Rosario Caltabiano, Stefania Staibano, Paolo Vigneri

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Simulation Analysis and Experimental Study on Strength Optimization of a Plug-In Oil Hose Joint by Chang Chen, Jikun Guo, Shifu Zhang, Qixin Zhang, Dongmei Zhang, Yongjie Niu, Hao Sun

“…The strength of the joint was optimized by applying materials with different properties and adjusting the circular angle of the joint. …”
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Multi-objective optimization of the design parameters of texture bottom profiles in a parallel slider by Nilesh D. Hingawe, Skylab P. Bhore

“…Abstract In this paper, a square textured parallel slider is considered for a study to improve the hydrodynamic performance of moving parts. The numerical method is employed for the analysis of a square texture with different bottom profiles: flat, triangle T1, triangle T2, and curved. …”
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