The clinical characteristics of Hirayama disease in females by Hongwei Wang, Wei Lei, Ye Tian, Jianwei Wu, Xiaosheng Ma, Feizhou Lyu, Xinlei Xia, Jingjuan Liang, Jianyuan Jiang, Hongli Wang

“…Discussion: Although females presented with Hirayama disease two years earlier than males, no other clinical differences were observed. Hirayama disease is likely associated with growth and development in puberty, and early identification, regardless of whether patients are male or female, is critical to optimizing prognosis. …”
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Regional patterns of genetic variants in expanded carrier screening: a next-generation sequencing pilot study in Fujian Province, China by Danhua Guo, Danhua Guo, Nani Zhou, Qianqian He, Qianqian He, Na Lin, Na Lin, Shuqiong He, Shuqiong He, Deqin He, Deqin He, Yifang Dai, Yifang Dai, Ying Li, Ying Li, Xuemei Chen, Xuemei Chen, Hailong Huang, Hailong Huang, Jia Jia, Hua Cao, Liangpu Xu, Liangpu Xu

“…BackgroundThis pilot study aimed to characterize the regional distribution of genetic variants associated with autosomal recessive and X-linked recessive (AR/XLR) conditions in Fujian Province, Southeast China, to inform the development of targeted carrier screening programs.MethodsAn expanded carrier screening (ECS) panel utilizing next-generation sequencing (NGS) technology was designed to analyze 332 genes associated with 343 AR/XLR conditions. …”
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Safety assessment of symptomatic intracranial atherosclerotic stenosis: a comparison between sole balloon angioplasty and medical treatment by Wen-feng Cao, Wen-feng Cao, An Wen, An Wen, Xian-min Cao, Ling-feng Wu, Ling-feng Wu, Yong-liang Zhou, Yong-liang Zhou, Zheng-bing Xiang, Zheng-bing Xiang, Wei Rao, Wei Rao, Quan-hong Chu, Quan-hong Chu, Wang-Wang Hong, Wang-Wang Hong, Shi-min Liu, Shi-min Liu

“…Simple balloon angioplasty (SBA), a less invasive and safer alternative to stent placement, is an effective alternative treatment for sICAS.MethodsWe conducted a retrospective analysis on patients with sICAS treated at the Jiangxi Provincial People’s Hospital between January 2020 and December 2023. …”
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Transcutaneous electrical nerve stimulation as an adjuvant treatment for thoracolumbar acute hyperesthesia in chondrodystrophic dogs: a prospective blinded controlled clinical stud... by Débora Gouveia, Débora Gouveia, Débora Gouveia, Ana Cardoso, Ana Cardoso, Carla Carvalho, Marina Moisés, André Coelho, André Coelho, André Coelho, Maria Manuel Balça, Maria Manuel Balça, Maria Manuel Balça, Rui Alvites, Rui Alvites, Rui Alvites, Rui Alvites, Ana Colette Maurício, Ana Colette Maurício, Ana Colette Maurício, António Ferreira, António Ferreira, Ângela Martins, Ângela Martins, Ângela Martins

“…This study aimed to evaluate the efficacy of TENS as an adjunctive treatment for thoracolumbar paraspinal hyperesthesia in dogs.MethodsThis prospective, blinded, controlled cohort study was conducted in a clinical setting. …”
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Psychological Well-being for educational counselors in the center of Erbil City by Payam Khasro Mirza, Omer Yassen Mala Ebrahim

“… • Identify the indication of statistical differences of the feeling level of the psychological quality according to gender variable. …”
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Nonlinear Relationship Between the Elderly’s Perception of Green Spaces and Their Activity Characteristics by Yuanjing WU, Yongyi YOU, Wei ZHOU, Siren LAN

“…To address this gap, this research employs the extreme gradient boosting (XGBoost) model to investigate the nonlinear relationship between the elderly’s perception of urban park green spaces and their activity characteristics, aiming to inform age-friendly park design and evidence-based green space planning strategies.MethodsThis research is based on 779 valid questionnaires collected from five representative urban parks in Fuzhou, a city experiencing rapid demographic aging and urban expansion. …”
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Early bevacizumab dose and time modifications may affect efficacy of atezolizumab plus bevacizumab for advanced hepatocellular carcinoma treatment by F. Rossari, D. Lavacchi, E. Alimenti, C. Soldà, F. Salani, L. Esposito, S. Foti, S. Camera, M. Persano, F. Lo Prinzi, F. Vitiello, E. Pellegrini, M. Bruccoleri, M.D. Rizzato, M. Caccese, I.G. Rapposelli, A. Guidolin, A. De Rosa, L. Antonuzzo, G. Masi, M.A. Iavarone, S. Lonardi, M. Rimini, A. Casadei-Gardini

“…Additionally, early bevacizumab dose/time modifications (eBEVmod) may negatively impact outcome. Materials and methods: Data from AtezBev-treated aHCC patients (n = 100) in five Italian institutions were retrospectively analyzed. …”
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Efficacy of acupuncture as adjunctive therapy for patients with acute exacerbation of chronic obstructive pulmonary disease: a systematic review and meta-analysis by Guofeng Li, Jimin Liu, Guixian Yang, Jiajia Li, Yuan He, Xinru Fei, Lai Wei, Dongkai Zhao

“…However, the weaning success rate did not show a statistically significant difference between the two groups (RR = 1.18, 95%CI 0.95 ~ 1.48, p = 0.14). …”
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Clinical application value of intracavitary PRP infusion combined with IVF-FET in patients with chronic endometritis by ZHANG Xiaotong, HAO Xiaoyuan, FANG Rui, HU Shuyao, MA Linkun, ZHAO Yaqi, HAN Wei

“…[Objective] To evaluate the clinical application value of intrauterine perfusion with platelet-rich plasma (PRP) combined with in vitro fertilization-frozen-thawed embryo transfer (IVF-FET) in patients with chronic endometritis (CE). [Methods] A randomized controlled trial (RCT) was conducted, enrolling 60 CE patients undergoing artificial cycle frozen embryo transfer at our hospital from January 2022 to January 2024. …”
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Study Protocol of Expanded Multicenter Prospective Cohort Study of Active Surveillance on Papillary Thyroid Microcarcinoma (MAeSTro-EXP) by Jae Hoon Moon, Eun Kyung Lee, Wonjae Cha, Young Jun Chai, Sun Wook Cho, June Young Choi, Sung Yong Choi, A Jung Chu, Eun-Jae Chung, Yul Hwangbo, Woo-Jin Jeong, Yuh-Seog Jung, Kyungsik Kim, Min Joo Kim, Su-jin Kim, Woochul Kim, Yoo Hyung Kim, Chang Yoon Lee, Ji Ye Lee, Kyu Eun Lee, Young Ki Lee, Hunjong Lim, Do Joon Park, Sue K. Park, Chang Hwan Ryu, Junsun Ryu, Jungirl Seok, Young Shin Song, Ka Hee Yi, Hyeong Won Yu, Eleanor White, Katerina Mastrocostas, Roderick J. Clifton-Bligh, Anthony Glover, Matti L. Gild, Ji-hoon Kim, Young Joo Park

“…The second phase of MAeSTro (MAeSTro-EXP) expands AS to low-risk papillary thyroid carcinoma (PTC) tumors larger than 1 cm, driven by the hypothesis that overall risk assessment outweighs absolute tumor size in surgical decision-making. Methods This protocol aims to address whether limiting AS to tumors smaller than 1 cm may result in unnecessary surgeries for low-risk PTCs detected during their rapid initial growth phase. …”
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Continuous arterial blood pressure indices and early hematoma expansion in patients with spontaneous intracerebral hemorrhage by Annerose Mengel, Vasileios Siokas, Rebecca Buesink, Sara Roesch, Kornelia Laichinger, Redina Ferizi, Efthimios Dardiotis, Patricia Schwarz, Jennifer Sartor-Pfeiffer, Constanze Single, Antje Giede-Jeppe, Till-Karsten Hauser, Sven Poli, Markus Krumbholz, Ulf Ziemann, Katharina Feil

“…Our study explores the potential link between BPV within the first 24 h after admission and HE in ICH. Methods: In a prospective cohort single-center study, we analyzed consecutive patients with spontaneous ICH. …”
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Impact of Diabetes and Glycemia on Cardiac Improvement and Adverse Events Following Mechanical Circulatory Support by Christos P. Kyriakopoulos, Iosif Taleb, Eleni Tseliou, Konstantinos Sideris, Rana Hamouche, Eleni Maneta, Marisca Nelson, Ethan Krauspe, Sean Selko, Joseph R. Visker, Elizabeth Dranow, Matthew L. Goodwin, Rami Alharethi, Omar Wever‐Pinzon, James C. Fang, Josef Stehlik, Craig H. Selzman, Thomas C. Hanff, Stavros G. Drakos

“…We sought to investigate the effect of glycemia on functional cardiac improvement, morbidity, and mortality in durable left ventricular assist device (LVAD) recipients. Methods and Results Consecutive patients with an LVAD were prospectively evaluated (n=531). …”
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Enhancing maize above-ground biomass estimation through multispectral, digital and LiDAR fusion on UAV platforms by Ziheng Feng, Zheqing Yang, Liunan Suo, Ke Wu, Zhiyao Ma, Haiyan Zhang, Jianzhao Duan, Wei Feng

“…Existing vegetation index (VI)-based maize AGB estimation methods using unmanned aerial platforms show limited generalizability due to insufficient integration of environmental and management factors. …”
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The Effect of SLM Spreader Structures on the Powder Spreading Dynamics Mechanism of Diamond Tools by HUANG Guoqin, ZHANG Jiangtao, ZHU Xiaowei, XU Yangli, SUN Long, DU Yulong, ZHANG Yunhe

“…Under the condition ofthe structural parameter optimization given in this work,the influence of spreader structures on the powder bedquality was comprehensively considered. …”
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Effects of UV-B radiation on the photosystem performance and fruit quality of strawberry in greenhouse by CHEN Yanrong, DING Shanming, LIU Zhen, SHI Huimei, XIAO Wei, CHEN Xiude, LI Ling, LI Dongmei

“…Improving the photosynthetic performance of strawberry leaves, assimilates synthesis and sugar accumulation in fruit through improved light quality regulation facilities may become a possibility. [Methods] In this study, Xuelixiang strawberries cultivated in a solar greenhouse were used as test materials. …”
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Development of a clinical decision support tool for Primary care Management of lower Urinary tract Symptoms in men: the PriMUS study by Adrian Edwards, Ridhi Agarwal, Janine Bates, Alison Bray, Sarah Milosevic, Emma Thomas-Jones, Michael Drinnan, Marcus Drake, Peter Michell, Bethan Pell, Haroon Ahmed, Natalie Joseph-Williams, Kerenza Hood, Yemisi Takwoingi, Chris Harding

“…Objectives 1 and 2: development of statistical models and diagnostic accuracy Methods Men presenting to their GP with LUTS were recruited prospectively from GP practices in Bristol, Newcastle upon Tyne and Wales. …”
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Biological protection of plants in agricultular landscape—state of the art, problems and ways of their decision by Sokolov M S, Kolombet L V

“…It is obvious, that in a complex with others, alternative (chemical) methods and means, the systemic approach is an integral condition of introducing bioprotection both in open agrobiocenosis, and in agrolandscape. …”
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Effect of tool angle in nanocutting of single crystal GaN using diamond cutter by Yongqiang WANG, Hao XIA, Zhihang HU, Shuaiyang ZHANG, Shaohui YIN

“…The primary objective is to establish clear relationships between tool angles, material removal mechanisms, defect generation (dislocations, phase transformation, amorphization), and final surface integrity, thereby providing foundational knowledge for optimizing ultra-precision machining processes. MethodsTo achieve these objectives, a rigorous multi-scale investigation is conducted, combining molecular dynamics simulation with experimental verification. …”
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Real-world patterns of immunoglobulin replacement therapy for infection prevention in common variable immunodeficiency: a multicenter nationwide study by Pedro Moral Moral, Pedro Moral Moral, Victor Garcia-Bustos, Victor Garcia-Bustos, Héctor Balastegui-Martin, Héctor Balastegui-Martin, Sandra Martínez Mercader, Sandra Martínez Mercader, Carmen Bracke, Carmen Bracke, Lourdes Mateu, Lourdes Mateu, Xavier Solanich, Xavier Solanich, Xavier Solanich, Arnau Antolí, Arnau Antolí, Arnau Antolí, Juan Luis Carrillo-Linares, Ángel Robles-Marhuenda, Francesc Puchades, Ana Pelaez Ballesta, Nuria López-Osle, Miguel Ángel Torralba-Cabeza, Ana María Bielsa Masdeu, Jorge Gil Niño, Nuria Tornador Gaya, Guillem Pascual Castellanos, Rosario Sánchez-Martínez, José Manuel Barragán-Casas, Andrés González-García, José Luís Patier de la Peña, Daniel López-Wolf, Antonia Mora Rufete, Alba Canovas Mora, Marta Dafne Cabañero-Navalon, Marta Dafne Cabañero-Navalon

“…This study aimed to evaluate real-world patterns of IgRT use in Spanish CVID patients and provide a comprehensive analysis of the factors associated with IVIg and SCIg administration in routine clinical practice.MethodsA cross-sectional, multicenter study was conducted using data from the GTEM-SEMI-CVID Registry, encompassing 212 adult CVID patients receiving IgRT across Spain. …”
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Early-life growth and emotional, behavior and cognitive outcomes in childhood and adolescence in the EU child cohort network: individual participant data meta-analysis of over 109,... by Romy Gonçalves, Sophia Blaauwendraad, Demetris Avraam, Andrea Beneíto, Marie-Aline Charles, Ahmed Elhakeem, Joaquin Escribano, Louise Etienne, Gonzalo García-Baquero Moneo, Ana Gonçalves Soares, Jasmin de Groot, Veit Grote, Dariusz Gruszfeld, Kathrin Guerlich, Monica Guxens, Barbara Heude, Berthold Koletzko, Aitana Lertxundi, Manuel Lozano, Hanan El Marroun, Rosie McEachan, Angela Pinot de Moira, Gillian Santorelli, Katrine Strandberg-Larsen, Muriel Tafflet, Chloe Vainqueur, Elvira Verduci, Martine Vrijheid, Marieke Welten, John Wright, Tiffany C. Yang, Romy Gaillard, Vincent W.V. Jaddoe

“…We assessed the associations of birth characteristics and early life growth with behavior and cognitive outcomes from childhood to adolescence. Methods: We used harmonized data of 109,481 children from 8 European birth cohorts. …”
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