Chronic Khat Chewing Induced High-Grade Hemorrhoidal Disease and Post-Operative Bleeding in Yemen by Al-Kubati WR

“…In Yemen, anorectal diseases, including hemorrhoids, are prevalent, and hemorrhoidectomy is frequently performed.Purpose: This study evaluates the relationship between chronic khat chewing and high-grade hemorrhoidal disease, as well as post-operative complications such as bleeding and pain.Patients and Methods: This prospective cross-sectional study included 1,896 patients aged 16– 85 years, meeting the inclusion criteria were included and followed for three months.Patients Were Divided Into Two Groups: Chronic khat chewers (n=1,492) and non-khat chewers (n=404) Data included khat habits, clinical assessments, digital rectal exams, anoproctoscopy, intraoperative findings, and post-operative outcomes.Results: Chronic khat chewing was strongly associated with thrombosed grade IV hemorrhoidal disease. …”
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Reflections and implementation strategies for constructing a standard system for deep coalbed methane exploration and exploitation by Xinjun CHEN, Zengqin LIU, Baojian SHEN, Shihu ZHAO, Jiaqi ZHANG, Jincheng YE

“…This leads to insufficient technical adaptability and pronounced risks of safety and environmental protection in the exploration and exploitation of deep CBM. MethodsThrough a systematic analysis of differences in geological and engineering characteristics between shallow and deep CBM, this study proposed a standard system framework following three dimensions (i.e., geological complexity, technical adaptability, and industrial and ecological collaboration) and four principles (scientific, systematic, practical, and dynamic natures). …”
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Muscular and Renal Safety of Ticagrelor with High-Intensity Statins: Retrospective Cohort Findings by Alshammari AS, Shalwala AA, Alnuhait MA, Alhazmi AY, Fagieha RE, Hallabi NB, Alandijani EA, Aloufi MA, Alharbi MS, Alzahrani RS, Elkholy EM, Elrggal ME, Alotaibi AS

“…This study aimed to evaluate these risks in a real-world clinical setting in Saudi Arabia.Methods: This retrospective observational cohort study was conducted at the Makkah Cardiology Center, Saudi Arabia. …”
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Smartphone-Based Telemonitoring for Better Oral Health With Toothbrushes: 6-Month Randomized Controlled Trial by Jaeyeon Kim, Yiseul Choi, Yoolbin Song, Wonse Park

“…However, further studies are needed to optimize feedback intervals and improve long-term adherence. …”
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O IMPACTO DAS EXPERIÊNCIAS ESTIGMATIZADORAS E AUTOESTIGMA NA SAÚDE MENTAL E NO COMPORTAMENTO SUICIDA: UM ESTUDO EM PAÍSES DE LÍNGUA PORTUGUESA by Henrique Marques Pereira, Mariana Quelhas Marques Coelho

“…Conclusions: Self-stigmatization has a negative impact on mental health and suicidal behavior, and countries should initiate mental health promotion campaigns and suicide prevention campaigns whose central goal should be to optimize people's quality of life…”
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Effectiveness of Topic-Based Chatbots on Mental Health Self-Care and Mental Well-Being: Randomized Controlled Trial by Alan C Y Tong, Kent T Y Wong, Wing W T Chung, Winnie W S Mak

“…ObjectiveThis study evaluated the effectiveness of a rule-based, topic-specific chatbot intervention in improving self-care efficacy, mental health literacy, self-care intention, self-care behaviors, and mental well-being immediately after 10 days and 1 month of its use. MethodsA 2-arm, assessor-blinded randomized controlled trial was conducted. …”
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Phosphate Peritoneal Equilibration Test, Hypothesizing New Parameters to Classify Peritoneal Phosphate Handling Through the Peritoneal Membrane by Francesca K. Martino, Chiara Ciotti, Anna Basso, Ruggero Zanella, Lucia F. Stefanelli, Dorella Del Prete, Federico Nalesso

“…Methods: We hypothesized a simple two-compartment model to describe phosphate removal driven by diffusion. …”
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Examining the Effects of the Protection Motivation Theory–Based Online Intervention on Improving the Cognitive Behavioral Outcomes of Caregivers of Children With Atopic Diseases: Q... by Dequan Shen, Qinzhun Zhang, Jiayu Tang, Jiahui Wu, Hui Huang, Yuchang Xu, Yinan He, Jialu He, Chengyin Ye

“…In the intervention group, caregivers exhibited stronger intentions and partial behavioral optimization (eg, environmental allergen control, with Z=–3.025; P=.002) and children showed improved medication adherence (Z=–4.457; P<.001) and alleviated eczema (Z=–3.112; P=.002) and allergic rhinitis symptoms (Z=–3.277; P<.001), although no significant differences emerged in asthma control (Z=–.830; P=.41) or food allergy–related caregiver burden (Z=–1.693; P=.09). …”
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Application of Six Sigma in the management of caregivers of inpatients in Department of Neurology during the COVID-19 outbreak (六西格玛管理法在新型冠状病毒肺炎疫情防控期间神经内科住院患者陪护人员管理中的应用)... by PAN Xi (潘习), XU Lan (徐岚), WANG Zhi (王稚)

“…Objective To evaluate the application of Six Sigma in the management of caregivers of inpatients in Department of Neurology during the COVID-19 outbreak. Methods Based on the Six Sigma approach, the management process of caregivers of inpatients in Department of Neurology was divided into five phases: definition, measurement, analysis, improvement and control. …”
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Exploring the Impact of the Multimodal CAPABLE eHealth Intervention on Health-Related Quality of Life in Patients With Melanoma Undergoing Immune-Checkpoint Inhibition: Prospective... by Itske Fraterman, Lucia Sacchi, Henk Mallo, Valentina Tibollo, Savannah Lucia Catherina Glaser, Stephanie Medlock, Ronald Cornet, Matteo Gabetta, Vitali Hisko, Vadzim Khadakou, Ella Barkan, Laura Del Campo, David Glasspool, Alexandra Kogan, Giordano Lanzola, Roy Leizer, Manuel Ottaviano, Mor Peleg, Konrad Śniatała, Aneta Lisowska, Szymon Wilk, Enea Parimbelli, Silvana Quaglini, Mimma Rizzo, Laura Deborah Locati, Annelies Boekhout, Lonneke V van de Poll-Franse, Sofie Wilgenhof

“…CAPABLE is an extensively tested eHealth app, including educational material, remote symptom monitoring, and well-being interventions. MethodsThis prospective pilot study compared an exploratory cohort that received the CAPABLE smartphone app and a multisensory smartwatch for 6 months (intervention) to a 2:1 individually matched historical prospective control group. …”
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Impact of Metastasectomy on Survival Outcomes in Colorectal Cancer: A Single Center Retrospective Study by Oğuzcan Kınıkoğlu, Yunus Emre Altıntaş, Goncagül Akdağ, Sedat Yıldırım, Hacer Şahika Yıldız, Akif Doğan, Uğur Özkerim, Sıla Öksüz, Alper Topal, Deniz Işık, Tuğba Başoğlu, Heves Sürmeli, Seval Ay, Hatice Odabaş, Nedim Turan

“…Our findings align with existing literature, particularly regarding the survival benefits of lung metastasectomy and the importance of achieving complete tumor resection Methods: This retrospective cohort study included 73 patients with colon cancer who underwent metastasectomy between January 2014 and June 2023. …”
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Lower body mass index is associated with the achievement of target LDL in patients using PCSK9 inhibitors in Taiwan by Kuan-Chieh Tu, Wei-Ting Chang, Hui-Wen Lin, Po-Lin Lin, Yen-Wen Wu, Chao-Feng Lin, Hung-I. Yeh, Min-Ji Charng, Po-Hsun Huang, Tsung-Hsien Lin, Wei-Wen Lin, I.-Chang Hsieh, Feng-Yu Kuo, Ching-Pei Chen, Sheng-Hsiang Lin, Yi-Heng Li

“…This study investigates the characteristics of patients who achieve target LDL-C reduction (< 70 mg/dl) after PCSK9 inhibitor therapy. Methods A multicenter, retrospective cohort study included patients initiating PCSK9 inhibitors at 11 teaching hospitals in Taiwan (2017–2021). …”
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Lifestyle habits and type 2 diabetes traits in patients from healthcare centers in Dubai, United Arab Emirates: a cross-sectional study by Kenana Hatab, Fadila Serdarevic, Fadila Serdarevic, Fadila Serdarevic, Aisha Yousuf, Sarah Al Ali, Khawla Eissa Ahmed M. Al Hajaj, Khawla Eissa Ahmed M. Al Hajaj, Fatima Mohamed Abdulla Mohamed Almarzooqi, Leena Tawfiq Swaidan, Elsheikh Farah ElHassan, Mahra Nooruddin Abdulwahid Kazim, Hanan Hamza Ahmed Abdalla, Hanan Ali Al-Muhaureq, Salah Mohammed Thabit, Hassan Abdulla BaKhamis, Sabina Semiz, Sabina Semiz

“…ObjectivesGiven the increasing prevalence of type 2 diabetes (T2D) in the United Arab Emirates (UAE), in this cross-sectional study we analyzed the dietary habits, physical activity, as well as anthropometric, clinical, and laboratory parameters in patients with T2D and nondiabetic (ND) subjects from the UAE.Subjects and MethodsThis study included 344 UAE nationals, age 18 or older, who completed a questionnaire to assess their dietary habits and physical activity. …”
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Impacts of Traditional Warm-Up and Post-Activation Potentiation on Muscle Endurance During the Back Squat: Response of Blood Lactate, Perceived Effort, and Time Under Tension by Taianda M. Amorim, Alexandre V. Gurgel, Viviane Faleiro, Thiago T. Guimarães, Estêvão R. Monteiro, Felipe G. Teixeira, Bruno Jotta, Tiago C. Figueiredo, Raquel C. Castiglione, Silvio R. Marques-Neto

“…This randomized crossover study compared the acute effects of traditional and PAP-based warm-ups on local muscular endurance (LME) during free weight back squats in resistance-trained men. Methods: Twelve trained males (age: 41.3 ± 5.7 years; one repetition maximum squat: 129.3 ± 14.3 kg) completed three randomized squat sessions: mobility with LME (M + LME), traditional warm-up with LME (T + LME), and PAP with LME (PAP + LME). …”
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Early Palliative Care Following Aborted Cancer Surgery: Results of a Prospective Feasibility Trial by Jordan M. Cloyd, MD, Rakhsha Khatri, BA, Angela Sarna, BS, Lena Stevens, PhD, Victor Heh, PhD, Mary Dillhoff, MD, Alex Kim, MD, Timothy M. Pawlik, MD, PhD, MPH, Aslam Ejaz, MD, Sharla Wells-Di Gregorio, PhD, Erin Scott, MD, Sachin S. Kale, MD

“…We hypothesized that early ambulatory PC referral following aborted cancer surgery would be feasible and acceptable. Methods:. This single-institution prospective clinical trial enrolled adult patients with gastrointestinal or hepatopancreatobiliary cancer with no prior PC exposure who had curative-intent oncologic surgery that was unexpectedly aborted. …”
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Historical overview, advancements, and future prospects of coalfield structure research in China by Daiyong CAO, Yiwen JU, Yucheng XIA, Bo JIANG, Shuzheng NING, Yingchun WEI, Anmin WANG, Xiaoming LI, Wenfeng ZHAN, Huantong LI, Lu WANG, Zhuocheng CAI

“…Amidst the ongoing energy structure optimization and the transformation and upgrading of coalfield geology in China, it is both practically and historically significant to review the history of coalfield structure research, summarize relevant experience, and contemplate future directions of the research under emerging circumstances.Methods Based on literature analysis, as well as the long-term research practices of the authors’ team, this study discusses the disciplinary attribute of coalfield structure research, reviews the history of this field both at home and abroad, and summarizes major achievements in China. …”
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The effect of taurine supplementation on markers of muscle damage and muscle pain in an athletic population: A systematic review and meta-analysis of randomized controlled trials a... by Elaheh Dehghani, Fatemeh Naeini, Sakineh Shab Bidar, Mohammad Beba, Erfan Mortezapour, Ruhollah Nourian, Khashayar Danandeh, Zahra Gohari Dezfuli, Kurosh Djafarian

“…This systematic review and meta-analysis examines the effects of TS on EIMD and muscle pain in athletes. Methods: PubMed, Scopus, and Web of Science were systematically searched for randomized controlled trials (RCTs) on TS in athletic populations until March 2025. …”
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Transcranial photobiomodulation improves functional brain networks and working memory in healthy older adults: An fNIRS study by Qin Yang, Xiujuan Qu, Can Sheng, Xing Zhao, Guanqun Chen, Xiaoni Wang, Yuxia Li, Wenying Du, Xiaoqi Wang, Yu Sun, Xiaobo Li, Haijing Niu, Ying Han

“…Methods: A total of 55 right-handed healthy older adults were randomly assigned to sham tPBM session group or active tPBM session group. …”
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Type 2 diabetes mellitus’ impact on heart failure patients’ exercise tolerance: a focus on maximal fat oxidation during exercise by Huiying Zhu, Huiying Zhu, Jianchao Pan, Jianxuan Wen, Jianxuan Wen, Xiaojing Dang, Xiaojing Dang, Xiankun Chen, Xiankun Chen, Yunxiang Fan, Yunxiang Fan, Weihui Lu, Weihui Lu, Wei Jiang, Wei Jiang

“…ObjectiveTo explore the impact of type 2 diabetes mellitus (T2DM) on exercise tolerance and fat oxidation capacity in patients with heart failure (HF).MethodsWe retrospectively analyzed 108 Chinese patients with HF who were divided into a diabetic group (T2DM group, n = 47) and a non-diabetic group (non-T2DM group, n = 61). …”
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Elevated mepolizumab levels in patients with severe asthma responsive to 1 year’s mepolizumab treatment by Takayasu Nishimaki, MD, Hitoshi Sasano, MD, PhD, Sonoko Harada, PhD, Tomohito Takeshige, MD, PhD, Yuuki Sandhu, MD, PhD, Yuki Tanabe, MD, Kei Matsuno, MD, PhD, Tetsutaro Nagaoka, MD, PhD, Jun Ito, MD, PhD, Ryo Atsuta, MD, PhD, Mayu Ohuchi, PhD, Shigehiro Yagishita, MD, PhD, Akinobu Hamada, PhD, Kazuhisa Takahashi, MD, PhD, Norihiro Harada, MD, PhD

“…Objective: We investigated the relationship between serum mepolizumab concentrations and treatment response in patients with severe asthma. Methods: Patients with mepolizumab-treated severe asthma were enrolled onto this prospective cohort study. …”
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