A WeChat-Based Decision Aid Intervention to Promote Informed Decision-Making for Family Members Regarding the Genetic Testing of Patients With Colorectal Cancer: Randomized Control... by Huanhuan Li, Yanjie Zhao, Wei Li, Wenxia Wang, Shengze Zhi, Yifan Wu, Qiqing Zhong, Rui Wang, Jiao Sun

“…ObjectiveThis study aims to determine whether a decision aid (DA) tool could promote informed decision-making among family members regarding the genetic testing of a patient with CRC. MethodsA single-center, parallel-group, randomized controlled trial was conducted. …”
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Microbial and clinical disparities in pneumonia: insights from metagenomic next-generation sequencing in patients with community-acquired and severe pneumonia by Wang Luo, Shuhua Zhang, Jinhuan Sun, Jinhuan Sun, Jianhui Xu, Weihua Huang, Ruiqing Hao, Zhao Ou, Zhao Ou, Ziyang Wen, Ziyang Wen, Daiwei Wang, Daiwei Wang, Guanhua Xiao, Hangming Dong

“…Beta diversity analysis demonstrated significant differences in microbial community composition between CAP and SP groups (p = 0.001), though alpha diversity metrics showed no significant differences. …”
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Polymorphism of TNF gene in acute coronary syndrome patients: data from the registries ORACLE I and ORACLE II by V. A. Brazhnik, L. О. Minushkina, A. О. Averkova, Е. A. Zubova, A. A. Rogozhina, М. A. Evdokimova, A. S. Galyavich, S. N. Tereshchenko, N. A. Koziolova, М. G. Glezer, А. V. Jagoda, О. I. Boeva, Е. V. Khoroletz, Е. А. Karmanchikova, V. O. Konstantinov, G. I. Speshilov, Е. N. Dankovtseva, D. А. Zateishchikov

“…To analyze possible association of the risk of adverse outcomes development in patients post acute coronary episode (ACS), with the polymorphism of gene TNF. Material and methods. To the study, patients included, that were under observation in 2 registry studies ORACLE I and II (Exacerbation of coronary heart disease: logic-probability ways of course prediction and treatment optimization). …”
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Construction and evaluation of a height prediction model for children with growth disorders treated with recombinant human growth hormone by Feng Zhu, Anle Wu, Lingling Chen, Ya Xia, Xiaoju Luo, Jieqian Zhu, Lina Huang, Yu Zhang

“…Methods A total of 786 children were included, randomly split into a derivation cohort (N = 551) and a test cohort (N = 235). …”
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Assessing HIV-1 subtype C infection dynamics, therapeutic responses and reservoir distribution using a humanized mouse model by Snehal Kaginkar, Leila Remling-Mulder, Ashashree Sahoo, Tejaswini Pandey, Pranay Gurav, Jyoti Sutar, Amit Kumar Singh, Ella Barnett, Sivasankar Panickan, Ramesh Akkina, Vainav Patel

“…Thus, treatment approaches developed for HIV-1B need to be suitably optimized for HIV-1C. A suitable animal model will help delineate comparative aspects of HIV-1C and HIV-1B infections.MethodsHere, we used a humanized mouse model to evaluate HIV-1C infection, disease progression, response to anti-retroviral therapy (ART) and viral rebound following therapy interruption. …”
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Integrating community perspectives to improve survey completion rates in public health research by refining controversial survey elements by Arleth A. Escoto, Angel Lomeli, Maria Linda Burola, Breanna Reyes, Ana Perez-Portillo, Scarlet Flores, Kayleigh Kornher, Norma Porras, Ariel Cohen, Linda Salgin, Borsika A. Rabin, Louise C. Laurent, Marva Seifert, Nicole A. Stadnick

“…This study used cognitive interviews (CIs), a methodological tool that can aid in developing and refining elements for multi-faceted assessments, and previous survey response patterns to refine, streamline, and increase response rates of RADx-UP Common Data Elements (CDEs) for survey/questionnaire use. Methods: Ten previously enrolled CO-CREATE study participants were interviewed between May–June 2023. …”
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Vaccination with inactivated SARS-CoV-2 vaccine TURKOVAC induces durable humoral and cellular immune responses up to 8 months by Seçil Yılmaz, Ahmet Eken, Ahmet Eken, Zafer Sezer, Zafer Sezer, Burcu Şen Bağcı, Serife Erdem, Medine Doğan Sarıkaya, Busra Kaplan, Busra Kaplan, Ahmet Inal, Ahmet Inal, Adnan Bayram, Gamze Kalın Unuvar, Gokmen Zararsız, Serra İlayda Yerlitas, Nuri Cakir, Shaikh Terkis Islam Pavel, Muhammet Ali Uygut, Hazel Yetiskin, Ates Kara, Aykut Ozdarendeli, Aykut Ozdarendeli

“…Additionally, the impact of two versus three doses of vaccination on these parameters was analyzed.MethodsVolunteers (n = 80) received two or three doses of TURKOVAC. …”
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Does Syndesmotic Fixation Technique Impact Complication Rates and Functional Outcomes Measured by PROMIS Scores Following Operative Repair of Ankle Fractures? by Steven Hadley BA, Rachel Bergman MD, John Peabody MD, Sarah Westvold MPH, Ryan Filler MD, Milap Patel DO, Anish Kadakia MD

“…We hypothesized that Tightrope and IB would reduce complications and improve PROMIS scores compared to screws. Methods: 782 patients who underwent ankle fracture surgery at a single institution between January 2016-December 2021 were reviewed retrospectively. …”
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Midterm outcomes of physician-modified endovascular grafts for repair of postdissection and degenerative thoracoabdominal aortic aneurysmsCentral MessagePerspective by Guangmin Yang, MD, Ming Zhang, MD, PhD, Yepeng Zhang, MD, Guangyan Wu, MD, Xiaoqiang Li, MD, PhD, Min Zhou, MD, PhD

“…We seek to compare the midterm outcomes of PMEGs in patients with postdissection (PD) and degenerative (DG) TAAAs. Methods: Data were analyzed for 126 patients (age 68 ± 13 years; 101 men [80.2%]) with TAAAs treated by PMEGs from 2017 to 2020, including 72 PD-TAAAs and 54 DG-TAAAs. …”
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Automatic segmentation and volume measurement of anterior visual pathway in brain 3D-T1WI using deep learning by Yongliang Han, Haixiang Wang, Qi Luo, Jingjie Wang, Chun Zeng, Qiao Zheng, Linquan Dai, Yiqiu Wei, Qiyuan Zhu, Wenlong Lin, Shaoguo Cui, Yongmei Li

“…We aim to explore the feasibility of automatic AVP segmentation and volume measurement in brain T1-weighted imaging (T1WI) using the 3D UX-Net deep-learning model.MethodsClinical data and brain 3D T1WI from 119 adults were retrospectively collected. …”
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VENETOCLAX-BASED VERSUS 7+3 INDUCTION THERAPY IN FIT YOUNGER ADULTS WITH NEWLY DIAGNOSED NON-CBF AML by Dmitrii Zhogolev, Nikita Pastukhov, Bella Aybova, Anna Smirnova, Ivan Moiseev, Sergey Bondarenko, Alexander Kulagin

“…Survival analysis was conducted using the Kaplan-Meier method and log-rank test. Cumulative incidences of relapse and NRM were assessed using competing risk models with Gray’s test. …”
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Functional and quality of life outcomes after partial glossectomy: a multi-institutional longitudinal study of the head and neck research network by Agnieszka Dzioba, Daniel Aalto, Georgina Papadopoulos-Nydam, Hadi Seikaly, Jana Rieger, Johan Wolfaardt, Martin Osswald, Jeffrey R. Harris, Daniel A. O’Connell, Cathy Lazarus, Mark Urken, Ilya Likhterov, Raymond L. Chai, Erika Rauscher, Daniel Buchbinder, Devin Okay, Risto-Pekka Happonen, Ilpo Kinnunen, Heikki Irjala, Tero Soukka, Juhani Laine, Head and Neck Research Network

“…Abstract Background While aggressive treatment for oral cancer may optimize survival, decrements in speech and swallowing function and quality of life often result. …”
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Survival benefits and toxicity effects of radiotherapy and immunotherapy treatments in melanoma patients with brain metastases: A meta-analysis by Jialing Wen, Xiangdi Meng, Wenchao Gu, Shenke Zhang, Li Sui, Gang Guo, Liang Yan, Wangcai Ren, Xuanzhang Tu, Kensuke Osada, Takashi Shimokawa, Yang Li, Liqiu Ma

“…Objective: To compare the efficacy and toxicity of four treatment strategies in patients with MBMs. Methods: A systematic literature search of the Cochrane, PubMed, Embase, Web of Science, and OVID Medline databases was performed until July 24, 2024. …”
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The sensitivity of aerosol data assimilation to vertical profiles: case study of dust storm assimilation with LOTOS-EUROS v2.2 by M. Pang, M. Pang, J. Jin, T. Yang, X. Chen, A. Segers, B. Buyantogtokh, Y. Gu, J. Li, H. X. Lin, H. X. Lin, H. Liao, W. Han

“…Aerosol data assimilation has gained popularity as it combines the advantages of both methods. Despite numerous studies in this domain, few have addressed the challenges faced in assimilating aerosol data with significant differences in magnitude and degree of freedom between the model state and observations, especially in the vertical direction. …”
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Comparison of Omega-3 polyunsaturated fatty acids bioavailability in fish oil and krill oil: Network Meta-analyses by Thi-Phuong-Thao Pham, Thi-Van Hoang, Phuc-Thao-Nguyen Cao, Thi-Thuy-Duong Le, Van-Thao-Nguyen Ho, Thi-Mai-Hoa Vu, Thi-Hoai-Thu Le, Huynh-Thien-Xuan Pham, Thanh-Thien Tran, Okti Ratna Mafruhah, Thi-Thuy-Linh Pham, Min-Tsang Hsieh, Hai-Anh Ha

“…Understanding these differences can optimize their therapeutic use. This study aims to compare the bioavailability of Omega-3 PUFAs in fish oil and krill oil using a network meta-analysis approach. …”
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Association between prognostic nutritional index and risk of moderate-to-severe basic activities of daily living dependence two years after hip fracture surgery in older adults by Qian Wu, Wenquan Ding, Zhongtai Zhang, Rui La, Dongqing You, Qingfeng Ding, Zhigang Zhang, Yuhao Cui, Lixin Huang, Lisong Li, Dinghua Jiang, Shenghao Wang

“…This study aimed to evaluate the prognostic value of the Prognostic Nutritional Index (PNI) in identifying older patients at risk of moderate-to-severe BADL dependence two years after hip fracture surgery. Methods A total of 526 older patients with hip fractures were included in the analysis. …”
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Laminectomy and fusion better maintains horizontal gaze than laminoplasty in cervical spondylotic myelopathy by Bradley T. Hammoor, MD, MS, Lara L. Cohen, MD, MPH, Grace X. Xiong, MD, Harry M. Lightsey, MD, Matthew Lindsey, MD, Harold A. Fogel, MD, Daniel G. Tobert, MD, Stuart H. Hershman, MD

“…This study evaluated postoperative horizontal gaze and cervical sagittal alignment in patients undergoing either procedure. Methods: In this retrospective cohort study at 2 academic centers, patients underwent either LF or LP. …”
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Atogepant for migraine prevention: a meta-analysis of safety and efficacy in adults by Adarsh Raja, Rabia Asim, Muhammad Hamza Shuja, Sandesh Raja, Tazheen Saleh Muhammad, Simran Bajaj, Abdul Hadi Ansari, Hamza Ali, Iffat Ambreen Magsi, Muhammad Hammad Faridi, Hamza Ali Hasnain Sheikh, Muhammad Junaid Imran, Muhammad Ahmed, Muhammad Sohaib Asghar, Muhammad Sohaib Asghar

“…Patients prefer oral therapies because they are easier to use, making atogepant, an orally accessible small-molecule CGRP receptor antagonist, a possible alternative.ObjectivesThis systematic review and meta-analysis compared the safety and effectiveness of atogepant with placebo in treating migraine.MethodsAdhering to the PRISMA guidelines, we meticulously gathered randomized controlled trials (RCTs) from databases including the Cochrane Library, PubMed, Science Direct, and ClinicalTrials.gov. …”
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Does Green Brazilian Propolis Extract Improve Functional Capacity in Symptomatic Chronic Coronary Disease?—A Pilot Randomized Trial by Clara Salles Figueiredo, Luiz Carlos Santana Passos, Caio Rebouças Fonseca Cafezeiro, Rodrigo Morel Vieira de Melo, Tainá Teixeira Viana, Eduardo Jorge Gomes de Oliveira, Andresa Aparecida Berretta, Marcelo Augusto Duarte Silveira

“…This pilot study aimed to evaluate whether six weeks of EPP-AF^® supplementation improves functional capacity assessed by treadmill exercise testing. <b>Methods</b>: This was a randomized, double-blind, placebo-controlled pilot study conducted at a coronary disease clinic in Brazil. …”
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Prediction of progressive fibrosing interstitial lung disease in patients with systemic sclerosis: insight from the CRDC cohort study by Xiaofeng Zeng, Yong Hou, Qian Wang, Jiuliang Zhao, Mengtao Li, Dong Xu, Xinwang Duan, Jiaxin Zhou, Min Hui

“…Background This study aims to establish a reliable prediction model of progressive fibrosing interstitial lung disease (PF-ILD) in patients with systemic sclerosis (SSc)-ILD, to achieve early risk stratification and to help better in preventing disease progression.Methods 304 SSc-ILD patients with no less than three pulmonary function tests within 6–24 months were included. …”
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