Antiphospholipid Antibodies and COVID‐19: A Systematic Review of Clinical Implications by Tahereh Sabaghian, Amir Behnam Kharazmi, Fatemeh Omidi, Bahareh Hajikhani, Shabnam Tehrani, Sayna Mardani, Amir Hashem Shahidi Bonjar, Rosella Centis, Lia D'Ambrosio, Giovanni Sotgiu, Fabio Angeli, Mohammad Javad Nasiri, Giovanni Battista Migliori

“…This systematic review explores the role of antiphospholipid antibodies in COVID‐19, focusing on their potential clinical implications. Methods This systematic review, following PRISMA guidelines, assesses studies exploring the link between antiphospholipid antibodies and COVID‐19. …”
Get full text

Longitudinal Analysis of Tetanus- and Influenza-Specific IgG Antibodies in Myeloma Patients by Sebastian Kobold, Tim Luetkens, Britta Marlen Bartels, Yanran Cao, York Hildebrandt, Orhan Sezer, Henrike Reinhard, Julia Templin, Katrin Bartels, Nesrine Lajmi, Friedrich Haag, Carsten Bokemeyer, Nicolaus Kröger, Djordje Atanackovic

“…We found that MM is associated with a profound disease- and therapy-related immunosuppression, which is compensated for a few months after alloSCT, most likely by application of IVIG. This and the differences regarding the recovery of anti-FLU and anti-TT antibody titers during the following years need to be taken into account for optimizing IVIG application and immunization after alloSCT.…”
Get full text

Comparative Analysis of Biochemical Parameters, Thermal Behavior, Rheological Features, and Gelling Characteristics of Thai Ligor Hybrid Chicken and Broiler Meats by Ngassa Julius Mussa, Chantira Wongnen, Warangkana Kitpipit, Worawan Panpipat, Mingyu Yin, Siriporn Riebroy Kim, Manat Chaijan

“…Understanding these variations in biochemical properties and functional behavior can help optimize processing methods and produce meat products of superior quality that meet consumer preferences.…”
Get full text

Evaluating pediatric tuberculosis dosing guidelines: A model-based individual data pooled analysis. by Lufina Tsirizani Galileya, Roeland E Wasmann, Chishala Chabala, Helena Rabie, Janice Lee, Irene Njahira Mukui, Anneke Hesseling, Heather Zar, Rob Aarnoutse, Anna Turkova, Diana Gibb, Mark F Cotton, Helen McIlleron, Paolo Denti

“…We pooled data from large pharmacokinetic studies to identify key covariates influencing drug exposure to optimize tuberculosis dosing in children.<h4>Methods and findings</h4>We used nonlinear mixed-effects modeling to characterize the pharmacokinetics of rifampicin, isoniazid, and pyrazinamide, and investigated the association of human immunodeficiency virus (HIV), antiretroviral therapy (ART), drug formulation, age, and body size with their pharmacokinetics. …”
Get full text

Significantly Increased Aqueous Solubility of Piperine via Nanoparticle Formulation Serves as the Most Critical Factor for Its Brain Uptake Enhancement by Li J, Leung SSY, Chan EHY, Jiang C, Ho ETY, Zuo Z

“…In the current study, formulation strategies and routes of administration were assessed to enhance systemic and brain uptake of piperine.Methods: Formulation of piperine nanoparticles (PIP NPs) was developed to enhance its solubility. …”
Get full text

Prognostic Value of the Goutallier Scale for Paravertebral Muscle Atrophy in Predicting Disability and Pain Outcomes in Degenerative Lumbar Spinal Stenosis: A Longitudinal Cohort S... by Giuseppe Corazzelli, Sergio Corvino, Chiara Di Domenico, Federico Russo, Vincenzo Meglio, Settimio Leonetti, Valentina Pizzuti, Marco Santilli, Alessandro D’Elia, Francesco Ricciardi, Sergio Paolini, Raffaele de Falco, Oreste de Divitiis, Vincenzo Esposito, Gualtiero Innocenzi

“…No significant differences in comorbidities or complication rates were identified across GS subgroups. …”
Get full text

Fournier gangrene is associated with increased length of stay and higher healthcare costs compared to non-perineal necrotizing soft tissue infections: a retrospective analysis of t... by Hayato Mitaka, Kristen McQuerry, Kelsey Karnik, Alexandre R. Marra, Toshio Naito, Patrick Ten Eyck, Paul G. Auwaerter, Yuji Yamada, Takaaki Kobayashi

“…However, comprehensive nationwide data remain limited. Methods: This retrospective cohort study analyzed the National Inpatient Sample (2016–2020) to compare outcomes between FG and non-perineal NSTIs. …”
Get full text

Chest trauma clinical practice guideline protects against delirium in patients with rib fractures by Valérie Courval, Raymond Tang, Peter Rose, Naisan Garraway, Robin Som, Jenna Kroeker, Anas Wess, Yuwei Yang, Bader Al-Zeer, Harjot Uppal, Patricia Balmes, Nasira Lakha, Angie Brisson, Jennifer Sakai, Emilie Joos

“…This prospective cohort study aimed to assess the impact of the CTCPG on pain management interventions and patient outcomes.Methods The study involved patients admitted between January 1, 2021 and December 31, 2021 (post-CTCPG cohort) and a historical control group admitted between November 1, 2018 and December 31, 2019 (pre-CTCPG cohort). …”
Get full text

Hepatocellular carcinoma in Korea: an analysis of the 2016-2018 Korean Nationwide Cancer Registry by Jihyun An, Young Chang, Gwang Hyeon Choi, Won Sohn, Jeong Eun Song, Hyunjae Shin, Jae Hyun Yoon, Jun Sik Yoon, Hye Young Jang, Eun Ju Cho, Ji Won Han, Suk Kyun Hong, Ju-Yeon Cho, Kyu-Won Jung, Eun Hye Park, Eunyang Kim, Bo Hyun Kim

“…This study evaluated the characteristics of Korean patients newly diagnosed with HCC in 2016-2018. Methods Data from the Korean Primary Liver Cancer Registry (KPLCR), a representative database of patients newly diagnosed with HCC in South Korea, were analyzed. …”
Get full text

Combined Positive Score and Cisplatin Sensitivity Are Prognostic Factors for Response to Nivolumab Therapy for Recurrent Metastatic Squamous Cell Carcinoma of the Head and Neck by Hiroaki Iijima, Akihiro Sakai, Koji Ebisumoto, Go Ogura, Mayu Yamauchi, Takanobu Teramura, Aritomo Yamazaki, Takane Watanabe, Toshihide Inagi, Ryoko Yanagiya, Ai Yamamoto, Hiroshi Ashida, Yoshiyuki Ota, Yurina Sato, Naoya Kobayashi, Daisuke Maki, Naoya Nakamura, Kenji Okami

“…This finding may help to optimize ICI therapy strategies.…”
Get full text

From virtual to reality: application of a novel 3D printing hollow model for early-stage lung cancer in the clinical teaching of thoracoscopic sublobar resection by Di Yang, Di Yang, Yafei Miao, Yafei Miao, Linqian Li, Linqian Li, Linqian Li, Qing Yu, Qing Yu, Qiang Guo, Hefei Li, Xuguang Zhang, Shujie Cheng, Shujie Cheng, Jinghua Li, Jinghua Li, Ke Zhang, Ke Zhang, Ke Zhang, Ke Zhang

“…This study evaluates the educational efficacy of a 3DP lung cancer model optimized for surgery in teaching thoracoscopic sublobar resection.MethodsA total of 62 clinical interns were randomly assigned into two groups: a 3D visualization (3DV) model group and a 3DP model group. …”
Get full text

How repeatable is PAPE effect: the impact of in-season isometric squat activation on countermovement jump performance enhancement in national level soccer players by Jakub Jarosz, Dawid Gawel, Pawel Grycmann, Piotr Aschenbrenner, Michal Spieszny, Michal Wilk, Michal Krzysztofik

“…However, pairwise McNemar tests did not reveal significant differences (p = 0.549–1.000), suggesting that while response distribution fluctuated, no specific session-to-session differences were detected. …”
Get full text

Multi-peak light sources can improve the physical and mechanical properties of a zirconia- and diatomite-based dental resin: an in vitro study by Jucivaldo Martins Gonçalves, Thalles Arievo Mota Sales, Cauã Santiago Figueiredo, Rafael Pinto de Mendonça, Jefferson Pires da Silva Júnior, Tânia Mara da Silva, Sérgio Eduardo de Paiva Gonçalves, Hércules Bezerra Dias

“…Material and Methods: A total of 270 specimens were prepared to evaluate the degree of conversion (DC), flexural strength (FS), elastic modulus (ME), water sorption (SOR), and solubility (SOL). …”
Get full text

Genetic and transcriptomic analyses of early-onset colon cancer (EOCC): a post hoc analysis of 2973 patients from two adjuvant randomized trials by A. Gandini, C. Gallois, H. Blons, C. Mulot, N. Agueeff, C. Lepage, R. Guimbaud, L. Mineur, J. Desramé, B. Chibaudel, A. de Reyniès, T. André, P. Laurent-Puig, J. Taieb

Get full text

Aging, HIV infection, and alcohol exert synergist effects on regional thalamic volumes resulting in functional impairment by Adolf Pfefferbaum, Natalie M. Zahr, Stephanie A. Sassoon, Rosemary Fama, Manojkumar Saranathan, Kilian M. Pohl, Edith V. Sullivan

“…Unknown is whether aging with HIV affects thalamic nuclei and associated functions differentially and whether the common comorbidity of alcohol use disorder (AUD) + HIV accelerates aging. Methods: This mixed cross-sectional/longitudinal design examined 216 control, 69 HIV, and 74 HIV + AUD participants, age 25–75 years old at initial visit, examined 1–8 times. …”
Get full text

Re-sperm collection with a short abstinence time: a strategy for successful cryopreservation in cryptozoospermia by Wen-Rui Zhao, Bo Liu, Xue-Feng Luo, Jin-Yan Xu, Chen Luo, Yuan Liu, Yang Xian, Fu-Ping Li

“…This study aimed to evaluate the impact of a 2-hour abstinence interval on sperm cryopreservation outcomes and assisted reproductive success in patients with cryptozoospermia. Methods: This retrospective study was conducted at a human sperm bank affiliated with a tertiary hospital from September 2023 to September 2024. …”
Get full text

Neuropsychological outcome of indoor rehabilitation in post-COVID-19 condition—results of the PoCoRe study by Michael Jöbges, Melanie Tempfli, Melanie Tempfli, Christoph Kohl, Christoph Herrmann, Stefan Kelm, Alexa Kupferschmitt, Alexa Kupferschmitt, Alexa Kupferschmitt, Ida Montanari, Nike Walter, Gerhard Suetfels, Thomas Loew, Volker Köllner, Volker Köllner, Thilo Hinterberger

“…The PoCoRe study aimed to evaluate the burden of neuropsychological deficits in PCC patients undergoing multidisciplinary indoor rehabilitation and to describe possible changes in this symptomatology.MethodsThe PoCoRe study, a prospective, non-randomized, controlled longitudinal study, recruited PCC patients from six German indoor rehabilitation centers. …”
Get full text

Impact of carbohydrate timing on glucose metabolism and substrate oxidation following high-intensity evening aerobic exercise in athletes: a randomized controlled study by Stig Mattsson, Fredrik Edin, Jonny Trinh, Peter Adolfsson, Johan Jendle, Stefan Pettersson

“…Specifically, it examined the effects of pre- or post-exercise carbohydrate (CHO) ingestion on glucose metabolism, glucose regulation, and overall substrate oxidation in well-trained athletes during and after physical exercise (PE), spanning the nocturnal period and the subsequent morning.Methods Ten male endurance cyclists participated in the study. …”
Get full text

Stress state calculation and potential failure risk identification of LNG storage tank inlet pipeline by Yanbing WANG, Hong ZHANG, Mengying XIA, Hongyu ZHOU, Baisong LI, Qiyu HUANG, Xiaoben LIU

“…Future efforts should focus on optimizing operational processes to reduce this temperature difference, assess safety risks, and ensure stable and reliable pipeline operation.…”
Get full text

Effectiveness of an Innovative Mobile-Based Perioperative Care Program for Women Undergoing Breast Cancer Surgery (iCareBreast): Randomized Controlled Trial by Yan Pang, Honggu He, Ruey-Pyng Ng, Nicole Kim Luan Lee, Me Me Win Htein, Xiao-Xin Zhao, Ying-Hong Li, Elizabeth Jiahui Chan, Lixia Zhu, Guang Yu Liu, Minna Pikkarainen, Swee-Ho Lim

“…The assessment focused on perioperative self-efficacy, anxiety, depression, fatigue, HR-QoL, and perioperative care satisfaction. MethodsA two-group randomized control trial was conducted at a tertiary hospital in Singapore. …”
Get full text