-
17881
Prevalence and clinical implications of anti-drug antibody formation and serum drug levels among patients with IBD receiving anti-TNF therapy: A cross-sectional study
Published 2025-03-01“…This study assesses the prevalence of anti-TNF drug levels (DLs) and antibodies (ATAbs) in patients with IBD in Saudi Arabia and explores their associations with IBD type and prior anti-TNF failure. Methods: This cross-sectional study included patients aged 14–75 years diagnosed with Crohn’s disease (CD) or ulcerative colitis (UC), treated with anti-TNF medications at King Fahad Medical City over January 2016 to December 2022. …”
Get full text
Article -
17882
Trends and forecast of drug-resistant tuberculosis: a global perspective from the GBD study 2021
Published 2025-03-01“…Recently, with the continued rise of DRTB, global TB prevention and control efforts have faced even greater challenges.AimsThis study aimed to quantify the changes in age-standardized incidence rate (ASIR) of two types of DRTB from 1991 to 2021 using the Global Burden of Disease (GBD) database, and to examine the epidemiological differences across various regions and countries and applied the autoregressive integrated moving average (ARIMA) model to predict the epidemiological trends of MDRTB and EDRTB from 2022 to 2030.MethodsData were extracted from the GBD database from 1991 to 2021. …”
Get full text
Article -
17883
Effect of Capsular Tension Ring on Refractive and Morphological Outcomes in Pseudoexfoliative Eyes
Published 2025-03-01“…Postoperative refractive PE was calculated using an optimized A-constant and the Kane formula.Results: A total of 25 eyes were included in each group. …”
Get full text
Article -
17884
Mental state as a predictor of outcome in spinal stenosis surgery: Four quadrants model integrating patient satisfaction and functional outcome
Published 2024-01-01“…This clinically relevant difference underscores the importance of addressing depression and anxiety in preoperative counselling to optimize patient satisfaction and functional outcomes.…”
Get full text
Article -
17885
Gouty arthritis patients’ diagnostic, biochemical, and hematological characteristics study: a single-center retrospective study
Published 2024-12-01“…Abstract Objective This study aims to investigate the diagnostic, biochemical, and hematological characteristics of patients with gouty arthritis and analyze their correlations with baseline characteristics to guide clinical practice, develop personalized treatment strategies, and improve patient outcomes. Methods A single-center retrospective analysis was conducted on 8,344 patients with acute gouty arthritis admitted to our hospital between January 2014 and December 2023. …”
Get full text
Article -
17886
Frequency and Antifungal Susceptibility Patterns of Candida Species Isolated from Clinical Samples of Patients Attending to a Tertiary Healthcare Setting in Karnataka, India
Published 2025-01-01“…Hegde Charitable Hospital, a 1000-bed tertiary healthcare teaching hospital in Mangalore. Subjects and Methods: Candida identification was performed using automated identification systems, while antifungal susceptibility testing was done using the VITEK 2 AST YS08 system. …”
Get full text
Article -
17887
Comparing the effectiveness of pregabalin and duloxetine in the management of neuropathic pain
Published 2025-04-01“…Such insights are crucial for optimizing neuropathic pain management strategies and improving patient outcomes. …”
Get full text
Article -
17888
Creatine in women’s health: bridging the gap from menstruation through pregnancy to menopause
Published 2025-12-01“…The review also considers the impact of hormonal changes on creatine metabolism and effectiveness as a dietary supplementation.Methods This is a narrative overview of historical and recent research evaluating the effects of creatine in women.Results Early studies demonstrated the benefits of creatine on exercise performance in women, though they often overlooked menstrual cycle variability. …”
Get full text
Article -
17889
Higher magnesium depletion score increases the risk of all‑cause and cardiovascular mortality in US adults with diabetes.
Published 2025-01-01“…This cohort study aims to explore the potential association between the MDS and all-cause and cardiovascular mortality in diabetic patients.<h4>Methods</h4>In this study, we analyzed data from 5,219 diabetic individuals from National Health and Nutrition Examination Survey (NHANES) 2003-2018. …”
Get full text
Article -
17890
Hospital length of stay and its predictors among surgical patients at public hospitals in Addis Ababa, Ethiopia
Published 2025-07-01“…Accordingly, this study aimed to assess the length of hospital stay and its predictors among surgical patients at public hospitals in Addis Ababa, Ethiopia.MethodsA prospective cohort study was conducted among 394 surgical patients from August 1 and November 30, 2023. …”
Get full text
Article -
17891
The impact of adult attachment on career decision-making in Chinese college students: the chain mediating role of self-differentiation and social support
Published 2025-04-01“…A direct path (β = −0.059, p < 0.05) confirmed attachment’s independent impact. Grade-level differences emerged: mediation effects were pronounced among lower-grade students, while seniors prioritized practical factors.DiscussionThe findings validate an emotion-psychology-resource transformation mechanism, demonstrating how secure attachment optimizes decisions through self-differentiation and social support. …”
Get full text
Article -
17892
YOUTUBE AS A SOURCE OF HEALTH INFORMATION: QUALITY AND RELIABILITY ANALYSIS OF SARCOPENIA-RELATED VIDEOS
Published 2024-12-01“…This research assessed the features and quality of YouTube videos concerning sarcopenia. Methods. On September 9, 2024, YouTube videos were viewed in incognito mode using the keywords «sarcopenia» and «loss of muscle strength.» …”
Get full text
Article -
17893
Biomechanical comparison of multiple zero-profile systems in anterior cervical discectomy and fusion: a finite element analysis
Published 2025-05-01“…The two-screw ZP (TSZP), four-screw ZP (FSZP), and ROI-C implants are frequently applied, yet the biomechanical performance across varying bone qualities remains unclear. Methods A finite element (FE) model of the cervical spine (C3-C7) was constructed with TSZP, FSZP, and ROI-C implants at C4/C5 to simulate normal and osteoporotic conditions. …”
Get full text
Article -
17894
Does Platelet-rich Plasma Delay Ankle Osteoarthritis Surgery? A Systematic Review
Published 2024-09-01“…Platelet-rich plasma (PRP) therapy has emerged as a potential treatment to alleviate symptoms and delay surgical interventions in ankle OA, akin to its established role in knee OA. Materials and methods: A systematic search was conducted across major databases from inception to present, following preferred reporting items for systematic reviews and meta-analyses (PRISMA) guidelines. …”
Get full text
Article -
17895
Pooled prevalence and subgroup variations of Tetralogy of Fallot among children and adolescents with congenital heart defect in Sub-Saharan Africa: A systematic review and meta-ana...
Published 2025-01-01“…<h4>Objective</h4>This review aims to systematically assess the prevalence of Tetralogy of Fallot among children and adolescents with congenital heart defects in Sub-Saharan Africa from January 2000 to January 2024.<h4>Methods</h4>All original observational studies focused on children and adolescent population diagnosed with congenital heart defects within Sub-Saharan Africa; reported the primary outcome of interest were included. …”
Get full text
Article -
17896
Radiation Awareness and X-Ray Use in Cardiology: An International Independent Web-Based Survey
Published 2024-01-01“…Radiation awareness and correct management of X-ray use are the cornerstone to comply with the principles of exposure optimization and justification. Methods and Results. …”
Get full text
Article -
17897
Correlation between vascular access satisfaction and demoralization syndrome in elderly patients with maintenance hemodialysis: a multi-center study
Published 2025-05-01“…Secondary objectives included identifying predictors of VAS and comparing DS severity between patients with high and low VAS scores. Methods A retrospective analysis was conducted from April 2024 to October 2024, involving 350 elderly MHD patients from three tertiary hospitals in China. …”
Get full text
Article -
17898
Surgical Timing and Postoperative Outcomes in Distal Femur Fractures: Does Early Intervention Matter?
Published 2025-06-01“…This study examines the relationship between surgical timing and postoperative outcomes in distal femur fracture patients. Methods This retrospective cohort study utilized the American College of Surgeons National Surgical Quality Improvement Program (ACS NSQIP) database to identify patients aged 65 and older who underwent surgery for distal femur fractures between 2015 and 2022. …”
Get full text
Article -
17899
A clinical study of coronary computed tomographic angiography in the diagnostic performance, risk assessment and guidance of treatment for coronary heart disease
Published 2025-12-01“…Objective This study aimed to evaluate the diagnostic performance, risk assessment, and treatment-guiding value of coronary computed tomographic angiography (CCTA) in patients with coronary heart disease (CHD).Methods The diagnostic value of CCTA for CHD was assessed by analyzing key parameters including sensitivity, specificity, accuracy, positive predictive value, and negative predictive value. …”
Get full text
Article -
17900
Crop classification in Google Earth Engine: leveraging Sentinel-1, Sentinel-2, European CAP data, and object-based machine-learning approaches
Published 2025-05-01“…Although object-based (OB) methods within Google Earth Engine (GEE) improve accuracy and output quality in contrast to pixel-based approaches, their application to crop classification remains relatively rare. …”
Get full text
Article