Individualized Analysis of Nipple‐Sparing Mastectomy Versus Modified Radical Mastectomy Using Deep Learning by Enzhao Zhu, Linmei Zhang, Pu Ai, Jiayi Wang, Chunyu Hu, Huiqing Pan, Weizhong Shi, Ziqin Xu, Yidan Fang, Zisheng Ai

“…To mitigate bias in treatment allocation, advanced statistical methods, including propensity score matching (PSM) and inverse probability treatment weighting (IPTW), were applied. …”
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A comparative study of patient–physician empathy in telehealth and traditional in-person visits by Abdulrahman M Jabour

“…The findings also suggest gender-specific preferences that could inform the optimization of telemedicine practices. Further research is recommended to explore these differences in more diverse populations.…”
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Candidate Interventions for Integrating Hypertension and Cardiovascular-Kidney-Metabolic Care in Primary Health Settings: HEARTS 2.0 Phase 1 by Andres Rosende, Cesar Romero, Donald J. DiPette, Jeffrey Brettler, Patrick Van der Stuyft, Gautam Satheesh, Pablo Perel, Niamh Chapman, Andrew E. Moran, Aletta E. Schutte, James E. Sharman, Vilma Irazola, Mark D. Huffman, Norm R. C. Campbell, Abdul Salam, Fernando Lanas, Antonio Coca, Sebastian Garcia-Zamora, Alejandro Ferreiro, Patricio Lopez-Jaramillo, Jorge Rico-Fontalvo, Emily Ridley, Dean Picone, David Flood, Daniel José Piñeiro, Carolina Neira Ojeda, Gonzalo Rodriguez, Irmgardt A. Wellmann, Marcelo Orias, Marcela Rivera, Matías Villatoro Reyes, Oyere Onuma, Shaun Ramroop, Taskeen Khan, Yamile Valdes Gonzalez, Weimar Kunz Sebba Barroso, Frida L. Plavnik, Eric Zuniga, Ana María Grassani, Carlos Tajer, Ezequiel Zaidel, Marcos J. Marin, Shana Cyr-Philbert, Ignacio Amorin, Miguel Angel Diaz Aguilera, Luiz Bortolotto, Alvaro Avezum, Antonio Luiz P. Ribeiro, Sheldon Tobe, Teresa Aumala, Sonia Angell, Pablo Lavados, Sheila Ouriques Martins, Ana Munera Echeverri, Marc G. Jaffe, Dorairaj Prabhakaran, Gianfranco Parati, Xin Hua Zhang, Anthony Rodgers, Salim Yusuf, Paul K. Whelton, Pedro Ordunez

“…This paper focuses on Phase 1, highlighting targeted interventions to improve and update the HEARTS Clinical Pathway. Methods: First, the coordinating group defined the project’s scope, objectives, principles, methodological framework, and tools. …”
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Impact of leadless pacemaker implantation site on cardiac synchronization and tricuspid regurgitation by Xiao-fei Gao, Hong Zhu, Jia-sheng Zhang, Ning-Zhang, Xiao-hong Pan, Yi-Zhou Xu

“…Abstract Background To investigate the optimization of leadless pacemaker placement and to assess its impact on heart synchronization and tricuspid regurgitation. …”
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To Compare and Evaluate the Efficacy of 1% Alendronate Gel and 10% Doxycycline Gel as an Adjunct to SRP in Patients with Chronic Periodontitis: A Randomized Controlled Clinical Tri... by Laloo Phassang, Radhika Kapoor, Prashant Tyagi, Amit Wadhawan

“…This method offers advantages over systemic delivery, such as reduced dosage and frequency, minimized systemic toxicity, and the avoidance of gastrointestinal issues and first-pass metabolism. …”
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Preparation of Hollow Nanocarbon Spheres Supported Bismuth and Electrocatalytic Reduction of CO₂ to Formic Acid by REN Mingye, Han Shihao, HU Jingbing, ZHAO Kun, GAO Pan, YANG Shaoxia

“…In order to solve the electrocatalysts with low reaction activity, low formic acid formation rate and poor long-term stability in the CO₂RR process, hollow nano-carbon sphere-supported bismuth oxide catalysts (Bi₂O₃@HCS) were prepared by template method. Metallic bismuth (Bi) has preferable HOCO* adsorption energy and hollow nanospheres have a good active component limiting effect. …”
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Exploring Human Use of Monoclonal Antibodies Against Critical Bacteria: A Scoping Review of Clinical Trials by Marco Piscaglia, Giovanni Scaglione, Camilla Genovese, Fabio Borgonovo, Fabio Brivio, Flavia Rampichini, Renata Grifantini, Alessandra Bandera, Andrea Gori, Marta Colaneri, Emanuele Palomba

“…This review evaluates the clinical efficacy, safety, and limitations of mAbs targeting critical bacterial pathogens, analyzing factors influencing therapeutic outcomes, and proposing strategies to optimize their clinical application. Methods A comprehensive analysis of clinical trials investigating antibacterial mAbs was conducted. …”
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Marketing Model of Tourism Enterprises Based on New Media Environment by Linna Wang, Xiaoyi Wang, Mei Song, Tianjiao Niu

“…Aiming at the problem of new media marketing strategy in shopping tourism scenic spots, this paper applies descriptive research, questionnaire survey, statistical processing, mathematical model, and other research methods to analyze the characteristics of new media such as prominence of personalization, increased audience selectivity, and diversified forms of expression presented by new media compared with traditional media, as well as the differences between the two in terms of communication status, dominant state, and audience state. 4I Marketing theory is applied to new media marketing, the changes in the marketing environment and marketing needs under the background of new media, and the extensive impact of these changes on the marketing mix strategy; the basic strategies and expected effects of new media marketing of tourism enterprises are studied from the aspects of product, price, channel, and promotion; the IPA model is constructed, and the empirical analysis of the shopping tourist attractions of Changshu Garment City in China is carried out. …”
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Computer-Assisted Evaluation of Zygomatic Fracture Outcomes: Case Series and Proposal of a Reproducible Workflow by Simone Benedetti, Andrea Frosolini, Flavia Cascino, Laura Viola Pignataro, Leonardo Franz, Gino Marioni, Guido Gabriele, Paolo Gennaro

“…CAS-optimized reductions demonstrated measurable improvements compared to traditional methods, underscoring their utility in outcome evaluation. …”
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THE ISSUES OF THE SUBSTANTIATION OF PEER AGRICULTURAL LAND PLOTS EXCHANGE IN UKRAINE by Mykola MALASHEVSKYI, Andrii TARNOPOLSKYI, Olena MALASHEVSKA

“…The results can be used for the improvement of land reallotment modeling based on heuristic and optimization methods.…”
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Repetitive Transcranial Magnetic Stimulation targeted with MRI based neuro-navigation in major depressive episode: a double-blind, multicenter randomized controlled trial. by Bruno Millet, Ghina Harika-Germaneau, Redwan Maatoug, Florian Naudet, Jean-Michel Reymann, Valérie Turmel, Jean-Marie Batail, Jacques Soulabaille, Nematollah Jaafari, Dominique Drapier

“…<h4>Method</h4>This evaluator- and patient-blind, multicenter RCT assessed the superiority in terms of efficacy of 10 HF rTMS sessions of the left DLPFC targeted with MRI based neuro-navigation versus similar sessions targeted by the standard 5 cm technique. …”
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Abstract 012: First‐line Stent Retriever Versus Contact Aspiration or Combined Technique for Posterior Cerebral Artery Occlusion EVT by Piers Klein, Thanh N Nguyen, Mohamad Abdalkader, Muhammad M Qureshi, Patrik Michel, Davide Strambo, Daniel Strbian, Christian Herweh, Markus A Möhlenbruch, Silja Räty, Marta Olivé‐Gadea, Marc Ribo, Marios Psychogios, Urs Fischer, Anh Nguyen, Joji Kuramatsu, David Haupenthal, Martin Köhrmann, Cornelius Deuschl, Jordi Kühne Escolà, Shadi Yaghi, Liqi Shu, Volker Puetz, Simon Nagel, Hend Abdelhamid, Negar Asdaghi, Judith Clark, Dominique P Cornelius Marterstock, Bruno Cunha, Guilherme Dabus, Jelle Demeestere, Shashvat Desai, Francesco Diana, Tobias Engelhorn, Johanna T Fifi, Isabel Fragata, Uta Hanning, Diogo Haussen, Ashutosh P Jadhav, Jessica Jesser, Maximilian Kaeder, Johannes Kaeshmacher, Daniel Kaiser, Kimmo Lappalainen, Italo L'Infante, Joao Pedro Marto, Hesham Masoud, Stavros Matsoukas, Volker Maus, Thomas R. Meinel, Lukas Meyer, Milena Miszczuk, Mahmoud Mohammaden, Maxim Mokin, Adnan Mujanovic, Raul Nogueira, Christian H Nolte, Sven Poli, Khouloud Poli, Joao Nuno Ramos, Christoph Riegler, Michele Romoli, Vasu Saini, Sergio A Salazar‐Marioni, Sunil A Sheth, Eberhard Siebert, James Siegler, Neil Suryadareva, Lieselotte Vandewalle, Pekka Virtanen, Charlotte S Weyland, Shadi Yaghi

“…Introduction The optimal reperfusion technique in patients with isolated posterior cerebral artery (PCA) occlusion is uncertain. …”
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Adjuvant combination and antigen multimerization shape neutralizing antibody and T cell responses to a SARS-CoV-2 RBD subunit vaccine by João Pedro da Silva Nunes, Mariângela de Oliveira Silva, Juliana de Souza Apostolico, Isabela Pazotti Daher, Rodolfo Ferreira Marques, Marcio Massao Yamamoto, Alexia Adrianne Venceslau Brito Carvalho, Maria Fernanda de Castro-Amarante, Edison Luiz Durigon, Carsten Wrenger, Luiz Mario Ramos Janini, Edmarcia Elisa de Souza, Robert Andreata-Santos, Juliana Terzi Maricato, Edecio Cunha-Neto, Edecio Cunha-Neto, Edecio Cunha-Neto, Jorge Kalil, Jorge Kalil, Silvia Beatriz Boscardin, Silvia Beatriz Boscardin, Daniela Santoro Rosa, Daniela Santoro Rosa

“…We also screened different adjuvants to optimize both humoral and cellular immunity. …”
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Cancer Awareness Among People Living with HIV (PLWH): Insights from an Italian Survey of Oncologists and Infectious Disease Specialists by Dalu D, Iardino R, Vaccher E, Lasagna A, Digaetano M, Leone AG, Ruggieri L, Massari E, Blondeaux E, Gori A, Mussini C, Rizzardini G, Bassetti M, Di Biagio A, Mastroianni CM, Brogonzoli L, Cascio M, Perrone F, Cinieri S, Beretta GD, La Verde N

“…More than a third of oncologists worked in a hospital without an infectious diseases department, using a remote method of communication for interdisciplinary discussion (telephone and Email were used in 64.5% of cases). …”
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An Enhanced Interval Type-2 Fuzzy C-Means Algorithm for Fuzzy Time Series Forecasting of Vegetation Dynamics: A Case Study from the Aksu Region, Xinjiang, China by Yongqi Chen, Li Liu, Jinhua Cao, Kexin Wang, Shengyang Li, Yue Yin

“…Accurate prediction of the Normalized Difference Vegetation Index (NDVI) is crucial for regional ecological management and precision decision-making. …”
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Thermal-mechanical coupled stress prediction of printed circuit heat exchanger in the supercritical CO2 Brayton cycle by Junlin Chen, Wenhai Du, Keyong Cheng, Xunfeng Li, Xiulan Huai, Jiangfeng Guo, Pengfei Lv, Hongsheng Dong

“…Dimensional analysis yielded predictive formulas for thermal stress (±13.3 % error) and mechanical stress (±14.3 % error), validated against finite element method results. A backpropagation neural network further improved prediction accuracy (errors <10 %). …”
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Assessing blood-brain barrier (BBB) integrity in an Alzheimer’s disease mouse model: is the BBB globally or locally disrupted? by Ehsan Nozohouri, Behnam Noorani, Dhavalkumar Patel, Yeseul Ahn, Sumaih Zoubi, Ulrich Bickel

“…Our findings challenge the assumption of widespread BBB leakiness in the Tg2576 AD model, highlighting the need for multi-method approaches to assess BBB integrity and optimize drug delivery in AD.…”
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Effective cellular and neutralizing immunity against SARS-CoV-2 after mRNA booster vaccination is associated with pDC and B cell activation by Dorit Fabricius, Carolin Ludwig, Carolin Ludwig, Matthias Proffen, Matthias Proffen, Janina Hägele, Janina Hägele, Judith Scholz, Judith Scholz, Christiane Vieweg, Christiane Vieweg, Immanuel Rode, Immanuel Rode, Simone Hoffmann, Simone Hoffmann, Sixten Körper, Sixten Körper, Hubert Schrezenmeier, Hubert Schrezenmeier, Bernd Jahrsdörfer, Bernd Jahrsdörfer

“…This study aimed to elucidate the immune responses, including B cell, plasmacytoid dendritic cell (pDC), and T cell activation, following mRNA booster vaccination.MethodsIn a longitudinal cohort study, 136 individuals received three different vaccination regimens: homologous mRNA, heterologous vector-mRNA-mRNA, or heterologous vector-vector-mRNA vaccinations. …”
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Advanced ECG Analysis to Evaluate Multimodal Exercise Effects on Cardiovascular Health by Ruta Brazdzionyte, Deivydas Velicka, Kristina Motiejunaite, Kristina Poderiene, Zivile Kairiukstiene

“…<i>Materials and Methods</i>: A total of 50 physically inactive males, aged 20–35 years, were recruited for a 6-week MEP. …”
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Establishing translational performance standards for TB therapy using rifampicin-based regimens in a male and female high-burden murine model by Jason E. Cummings, Lisa Woolhiser, Barbara Graham, Gregory T. Robertson, M. Nurul Islam, Richard A. Slayden

“…Abstract Background Establishing efficacy benchmarks in preclinical tuberculosis (TB) models is essential for optimizing and prioritizing therapeutic regimens. However, standardized classification methods for comparing high-performing regimens are currently lacking. …”
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