Co-design of a routine clinical review to improve the safety of high dose radical cure treatment for Plasmodium vivax malaria: findings from Cambodia and Ethiopia by Sarah A. Cassidy-Seyoum, Muthoni Mwaura, Keoratha Chheng, Muhaba Kejela, Kansite Gellebo Korra, Tsegaberhan Wodaj, Tamiru Shibiru Degaga, Michelle S. Hsiang, Lorenz von Seidlein, Rupam Tripura, Bipin Adhikari, Benedikt Ley, Dysoley Lek, Ric N. Price, Nora Engel, Kamala Thriemer

“…A clinical review visit on day 3 post-treatment initiation could facilitate adherence and improve safety, but it is unclear how it could be integrated into routine malaria care. Methods Between March and September 2023, focus group discussions (FGDs) with P. vivax malaria patients and healthcare providers were conducted in Cambodia and Ethiopia. …”
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Effects of vegetation restoration on soil fungi community structure and assembly process in a semiarid alpine mining region by Yuanyuan Xue, Yuanyuan Xue, Wei Liu, Qi Feng, Meng Zhu, Jutao Zhang, Lingge Wang, Lingge Wang, Zexia Chen, Zexia Chen, Xuejiao Li, Xuejiao Li

“…Despite its ecological significance, current comprehension regarding the structure composition and assembly mechanisms of soil fungal communities following vegetation restoration in these fragile ecosystems remains insufficient.MethodsWe used the high-throughput sequencing and null model analysis to determine the variations and environmental drivers of soil fungal community structures and assembly processes across different restoration chronosequences (natural plant sites, unrestored sites, 2-year restoration sites, and 6-year restoration sites) in a semiarid alpine coal mining region.ResultsArtificial vegetation restoration significantly enhanced the α diversity of soil fungal communities while reducing β diversity. …”
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Does Stricter Command-and-Control Environmental Regulation Promote Total Factor Productivity? Evidence from China’s Industrial Enterprises by Wei Chen, Luwen Gao, Xing Xu, Yan Zeng

“…This study selects the policy of China’s National Environmental Protection “Eleventh Five-Year Plan” as a quasi-natural experiment and uses the difference-in-differences (DID) method to analyze the effect of stricter command-controlled environmental regulations on total factor productivity from the enterprise level. …”
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Molecular modelling of four penicillins: bencylpenicillin, phenoxymethylpenicillin, ampicillin and amoxicillin by Elso Manuel Cruz Cruz, Eslhey María Sánchez Domínguez

“…<br /><strong>Objective:</strong>To compare structural properties, density of the atomic charges and the frontier orbitals of four penicillins: bencylpenicillin, phenoxymethylpenicillin, ampicillin and amoxicillin. <strong><br />Method:</strong>The molecular structures were optimized with PM3 semiempirical calculi. …”
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School-based management practices and utilization of special education fund by Edwin T. Castillo, Maria Kristina M. Cay

“…Guided by Musgrave's (1959) theory of public finance and Dalton's (1922) principle of maximum social advantage, the research employed a mixed-method explanatory sequential design. Data were gathered from 232 respondents using purposive sampling, with a validated questionnaire as the primary instrument. …”
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The Impact of Government Intervention in Rural Tourism Development on Residents’ Income: A Quasi-Natural Experiment from China by Shuaishuai Li, Shuping Shen, Yang Hu, Ruiqi Sun

“…This study investigates the relationship between government intervention in rural tourism and the income growth of rural residents by utilizing a Difference-in-Differences method based on county-level data from the China County-Level Statistical Yearbooks from 2006 to 2022. …”
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Metabolism and immune responses of striped hamsters to ectoparasite challenges: insights from transcriptomic analysis by Xinchang Lun, Yiguan Wang, Ning Zhao, Yujuan Yue, Fengxia Meng, Qiyong Liu, Xiuping Song, Ying Liang, Liang Lu

“…Hosts adjust their physiological and immune states to optimize survival strategies during different ectoparasite stages, enhancing our understanding of host-ectoparasite interactions. …”
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Longitudinal analysis of hsa-miR-3163, hsa-miR-124-3p, hsa-miR-548c-3p, and hsa-miR-27a-3p as prognostic biomarkers in HIV-infected patients by Ilker Inanç Balkan, Ilker Inanç Balkan, Ilker Inanç Balkan, Andleeb Shahzadi, Haktan Sönmez, Burhaneddin Oktan, Muhammad Ihtisham Umar, Bilgül Mete, Fehmi Tabak, Günnur Deniz, Umut Can Küçüksezer

“…This study aimed to evaluate the expression and diagnostic potential of in silico-identified miRNAs (miR-124-3p, miR-27a-3p, miR-548ac-3p, miR-3163) before and during antiretroviral treatment (ART), together with their correlations with immunological markers (CD4 count, CD4/CD45 ratio) and virological parameters (HIV RNA load).MethodsBlood samples and clinical data of 16 patients were collected at 4 different time points; before the initiation of ART (baseline), 1st, 2nd and 6th months following HIV diagnosis. 16 healthy controls were enrolled to this study. …”
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CONCOMITANT CARDIOVASCULAR DISEASES AND ANTIHYPERTENSIVE TREATMENT IN OUTPATIENT PRACTICE (BY THE RECVASA REGISTRY DATA) by M. M. Loukianov, S. A. Boytsov, S. S. Yakushin, S. Yu. Martsevich, A. N. Vorobyev, A. V. Zagrebelnyy, N. N. Nikulina, K. G. Pereverzeva, E. A. Pravkina, A. D. Deev, E. V. Kudryashov, E. N. Belova

“…To study a pattern of concomitant cardiovascular diseases (CVDs) and to estimate particularities and quality of medical antihypertensive therapy in hypertensive patients in real outpatient practice with a help of the Registry in Ryazan region.Material and methods. A total of 3690 patients with hypertension, ischemic heart disease, chronic heart failure and atrial fibrillation, who had attended general practitioners and cardiologists of 3 outpatient clinics in Ryazan city, were enrolled in the outpatient Registry of cardiovascular diseases (RECVASA). …”
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Exploring lymphocyte subsets in COVID-19 patients: insights from a tertiary academic medical center with a high proportion of patients on immunosuppression by Katrijn Daenen, Katrijn Daenen, Samantha van Hooijdonk, Kirby Tong-Minh, Kirby Tong-Minh, Willem A. Dik, Petrus M. van Hagen, Petrus M. van Hagen, Jilske A. Huijben, Diederik Gommers, Eric C. M. van Gorp, Eric C. M. van Gorp, Henrik Endeman, Virgil A. S. H. Dalm, Virgil A. S. H. Dalm

“…Given that immunosuppressive drugs significantly impact lymphocyte profiles, we aimed to determine the association between prior use of immunosuppressive drugs, lymphocyte subsets, and COVID-19 severity in our population with a high prevalence of immunosuppression.MethodsIn 2021, suspected COVID-19 patients were included in the ED. …”
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Synthesis, Anticancer Screening, and In Silico Evaluations of Thieno[2,3-<i>c</i>]pyridine Derivatives as Hsp90 Inhibitors by Balakumar Chandrasekaran, Mohammad F. Bayan, Ali Hmedat, Bilal A. Al-Jaidi, Deniz M. Al-Tawalbeh, Duaa Abuarqoub, Anas J. Rasras, Da’san M. M. Jaradat, Abdel Naser Dakkah, Wafa Hourani, Rajshekhar Karpoormath

“…<b>Conclusion</b>: The compound <b>6i</b> induced cell death via mechanisms that are different from apoptosis. Thus, the synthesized thieno[2,3-<i>c</i>]pyridine derivatives can be suitable lead compounds to be optimized to obtain potent anticancer agents through Hsp90 inhibition.…”
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Specular Reflection Image Enhancement Based on a Dark Channel Prior by Ye Xin, Zhenhong Jia, Jie Yang, Nikola K. Kasabov

“…Experimental results show that this method can effectively enhance the information in specular highlight images, and its processing results are obviously better than those of other algorithms.…”
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Fabrication-Tolerant Single-Transverse-Mode Supersymmetric Laser Arrays by Ruigang Zhang, Yu Lu, Tiange Wu, Sikang Yang, Kaiyuan Wang, Qiaomu Hu, Yunlong Li, Deming Liu, Shuang Zheng, Minming Zhang

“…Two independent superpartners are introduced on both sides of the main array, with one coupling and eliminating the higher-order odd symmetry supermodes, and the other coupling and eliminating the higher-order even symmetry supermodes in the main array, enabling more efficient coupling of higher-order transverse modes into the lossy superpartners, which leads to the increased loss of high-order supermodes. RDS design method is used to improve the single-transverse-mode characteristics with fabrication tolerance, which considers the fabrication error in ridge waveguide width during the optimization process. …”
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Global estimation of dengue disability weights based on clinical manifestations data by Han-Qi Ouyang, Zi-Yu Zhao, Okugbe Ebiotubo Ohore, Wei-Hao Li, Li Hong, Li-Ying Wang, Hong-Rui Zhang, Fu-Chun Zhang, Raman Velayudhan, Daniel Argaw Dagne, Ibrahima Socé Fall, Guo-Jing Yang

“…Methods We conducted a systematic search across six databases (Scopus, Web of Science, PubMed, China National Knowledge Infrastructure, Wanfang Data, and Database of Chinese sci-tech periodicals) for studies on human dengue clinical manifestations or infection from the establishment of each database through December 31, 2023. …”
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Impact of genetic risk and lifestyles on cardiovascular disease-free and total life expectancy: a cohort study by Dong Sun, Qiufen Sun, Yinqi Ding, Canqing Yu, Dianjianyi Sun, Yuanjie Pang, Pei Pei, Ling Yang, Iona Y. Millwood, Robin G. Walters, Huaidong Du, Jun Zhang, Dan Schmidt, Junshi Chen, Zhengming Chen, Liming Li, Jun Lv, the China Kadoorie Biobank Collaborative Group

“…Methods The China Kadoorie Biobank recruited participants from five urban and five rural areas across China during 2004–2008 and followed them up till December 31, 2018. …”
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Assessment of risk factors for high-grade cervical or endometrial lesions to triage women with AGC-FN: a retrospective study by Shuxia Xu, Tingting Jiang, Xiaodan Mao, Liangzhi Cai, Xite Lin, Yao Tong, Binhua Dong, Pengming Sun

“…Methods This retrospective utilized data from the China’s Fujian Cervical Pilot Project (FCPP). …”
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Effects of inter-culture, arabinogalactan proteins, and hydrogen peroxide on the plant regeneration of wheat immature embryos by Wei ZHANG, Xin-min WANG, Rong FAN, Gui-xiang YIN, Ke WANG, Li-pu DU, Le-le XIAO, Xing-guo YE

“…Moreover CS (79.05%), JM22 (7.55%), CN16 (101.87%), YM18 (365.56%), Yangmai 20 (YM20) (10.48%), and CB301 (187.40%) were more responsive to 0.005 ‰ of H2O2, and NC4 (35.37%) obtained the highest shoot regeneration rates at 0.01 ‰ of H2O2. Overall, these two methods, inter-culture and AGP (or H2O2) application, can be further applied to wheat transgenic research.…”
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Co-isolation of human donor eye cells and development of oncogene-mutated melanocytes to study uveal melanoma by Yunxi Chen, Eva Jin, Mohamed Abdouh, Éric Bonneil, Daniel Alexander Jimenez Cruz, Thupten Tsering, Qianqian Zhou, Aurélie Fuentes-Rodriguez, Alexandra Bartolomucci, Alicia Goyeneche, Solange Landreville, Miguel N. Burnier, Julia V. Burnier

“…NCM growth and behavior were characterized under different culture conditions (i.e., supplementation with serum and 12-O-tetradecanoylphorbol-13-acetate) to determine optimized protocols. …”
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Assessment of intra-fractional and inter-fractional motion in esophageal cancer treated with intensity-modulated proton therapy by Xiaoying Fan, Shuting Wang, Weijie Li, Kangning Meng, Wei Huang, Yong Yin, Tianyuan Dai

“…Seven IMPT plans with different robust optimization parameters were designed for the 21 Ginter patient. …”
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Machine learning algorithms to predict stroke in China based on causal inference of time series analysis by Qizhi Zheng, Ayang Zhao, Xinzhu Wang, Yanhong Bai, Zikun Wang, Xiuying Wang, Xianzhang Zeng, Guanghui Dong

“…Setting CHARLS adopts a multi-stage probability sampling method, covering samples from 28 provinces, and collects data every two years through computer-aided personal interviews (CAPI). …”
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