Long-Term Effectiveness and Safety of Proactive Therapeutic Drug Monitoring of Infliximab in Paediatric Inflammatory Bowel Disease: A Real-World Study by Susana Clemente Bautista, Óscar Segarra Cantón, Núria Padullés-Zamora, Sonia García García, Marina Álvarez Beltrán, María Larrosa García, Maria Josep Cabañas Poy, Maria Teresa Sanz-Martínez, Ana Vázquez, Maria Queralt Gorgas Torner, Marta Miarons

“…Background: This study evaluated the long-term effectiveness and safety of a multidisciplinary early proactive therapeutic drug monitoring (TDM) program combined with Bayesian forecasting for infliximab (IFX) dose adjustment in a real-world dataset of paediatric patients with inflammatory bowel disease (IBD). Methods: A descriptive, ambispective, single-centre study of paediatric patients with IBD who underwent IFX serum concentration measurements between September 2015 and September 2023. …”
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Controlled-release fertilizer affects leaf nitrogen allocation and photosynthesis to improve nitrogen use efficiency and yield in the sunflower field by Wenhao Ren, Xianyue Li, Xianyue Li, Xianyue Li, Tingxi Liu, Tingxi Liu, Ning Chen, Maoxin Xin, Qian Qi, Bin Liu

“…However, the changes in N allocation to enhance the photosynthesis under CRF have rarely been addressed.MethodsA two-year field experiment was conducted in the Hetao Irrigation District, Inner Mongolia, China from 2019 to 2020 to evaluate the effects of different fertilization strategies on soil NO3-N concentration, leaf nitrogen content, photosynthetic characteristics, yield, and nitrogen use efficiency (NUE) in sunflowers. …”
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Full-Wave Simulation of a Solenoid RF Coil for Small Animal Magnetic Resonance Imaging with a Clinical Scanner by Giulio Giovannetti, Francesca Frijia, Alessandra Flori, Vincenzo Positano

“…This paper describes the full-wave simulation of a solenoidal coil for Magnetic Resonance Imaging (MRI) using the finite-difference time-domain (FDTD) method. Such a simulator enables the estimation of the coil’s magnetic field pattern in a loaded condition, the coil inductance, and the sample-induced resistance. …”
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Fluticasone propionate in chronic rhinosinusitis with nasal polyps (CRSwNP): an artificial intelligence-driven consensus by Emilio Avallone, Raffaella Iannella, Antonella Di Lullo, Michele Grasso, Salvatore Musto, Enzo Piermichele Troncone, Giuseppe Tortoriello, Bernardino Cassiano, Simona Nappi, Gianluca Bava, Giovanna Piazzetta, Giovanni Tomacelli, Aurelio D’Ecclesia, Giacomo Spinato, Giacomo Matrone, Doriano Politi, Carlo De Luca, Claudio Caporale, Livio Presutti, Livio Presutti, Gabriele Molteni, Gabriele Molteni, Ernesto Pasquini, Francesco Panu, Simonetta Masieri, Stefano Di Girolamo, Giulio Cesare Passali, Luca de Campora, Giandomenico Maggiore, Domenico Di Maria

“…However, the need for a consensus on its use stems from the increasing focus on optimizing topical therapies to improve clinical outcomes and minimize systemic side effects.Materials and methodsThe Butterfly Decisions AI platform facilitated the collection and integration of evaluations and feedback, facilitating an expert consensus on 13 statements.ResultsThe participants agreed highly on the different statements. …”
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Regulatory effects of laser irradiation on greenhouse-grown strawberry productivity by LEI Kangqi, YANG Han, CHENG Feng, LEI Yumeng, LI Jianwei, QI Yetong, LI Zhitao, QI Xingjiang

“…The yield enhancement showed an increasing trend followed by stability with increasing laser intensity, with no significant difference between 0.5 and 1 PPFD treatments, indicating optimal effectiveness. …”
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Machine learning-based classification model to differentiate subtypes of invasive breast cancer using MRI by Nadesalingam Paripooranan, Warnakulasuriya Buddhini Nirasha, H. R. P. Perera, Sahan M. Vijithananda, P. Badra Hewavithana, Lahanda Purage Givanthika Sherminie, Mohan L. Jayatilake

“…Among the morphological features, the total volume of the contralateral breast, surface area of the contralateral breast, breast density, and the ratio of the total volume of the contralateral breast to its surface area had higher F-scores, indicating that the dimensions of the contralateral breast could be an important factor in differentiating IDC and ILC.ConclusionThis study successfully developed and optimized a predictive model based on breast morphological features to differentiate IDC and ILC using machine learning methods.…”
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The unexploited potential of data systems tracking medicines utilization: an opportunity to improve access to oncology combination therapies by Steven Simoens, David Dodwell, Michael Hartevelt, Peter Lindgren, Peter Lindgren, Michele Pistollato, Lisa Pont, Caridad Pontes, Alexander Roediger, Antun Sablek, Eric Van Ganse, Qinyi Wang, Chris Wenger, Tim Wilsdon, Entela Xoxi, Entela Xoxi, Brian Godman, Brian Godman

“…These include data quality, access for different stakeholders, minimizing the burden of data entry and management, and increasing support from national authorities to foster multi-stakeholder engagement.ConclusionWhile most countries possess data systems that could serve as a foundation for tracking combination oncology therapies, these systems require optimization and proper implementation. …”
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A Review of Research on Flight Delay Propagation: Current Situation and Prospect by N. Li, H. G. Yao

“…Among the methods for predicting delay propagation, models based on machine learning algorithms account for a large proportion and have shown good prediction performance. …”
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Prediction of Early Diagnosis in Ovarian Cancer Patients Using Machine Learning Approaches with Boruta and Advanced Feature Selection by Tuğçe Öznacar, Tunç Güler

“…By eliminating irrelevant features, this approach could guide clinicians towards more accurate results and optimize diagnostic precision. Methods: This study included both patients with and without ovarian cancer, creating a dataset containing 50 independent variables/features. …”
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Multi-Criteria Decision Analysis in Drug Discovery by Rafał A. Bachorz, Michael S. Lawless, David W. Miller, Jeremy O. Jones

“…To address this, we recently implemented a new Multi-Criteria Decision Analysis (MCDA) method as part of the AI-powered Drug Design (AIDD^TM) technology initiative. …”
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Pilot dispatching problem along a maritime corridor: a case study in the St. Lawrence River by Milad Hematian, Jean-François Audy, Mikael Rönnqvist

“…It integrates a comprehensive set of time-based performance measures, including working time, waiting time, and skill level differences, to optimize fairness and operational efficiency in pilot dispatching. …”
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Dietary soy protein reverses obesity-induced liver steatosis and alters fecal microbial composition independent of isoflavone level by Reza Hakkak, Reza Hakkak, Reza Hakkak, Soheila Korourian, Wei Li, Beverly Spray, Nathan C. Twaddle, Christopher E. Randolph, Elisabet Børsheim, Elisabet Børsheim, Elisabet Børsheim, Michael S. Robeson II

“…The current study was designed to test whether SPC-LIF and SPC-HIF diets would reverse liver steatosis and alter fecal microbial composition in adult obese Zucker rats with existing steatosis.MethodsSix-week-old male obese Zucker rats (n = 26) were fed a casein control diet (CAS) for 8 weeks and 7 rats were randomly selected and sacrificed to confirm liver steatosis. …”
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Resumption of Employment after Cervical Cancer Surgery: a 3-Year Follow-Up Study of Long-term Outcomes by Dmitry V. Blinov, Antonina G. Solopova, Elena V. Gameeva, Nazim G. Badalov, Mikhail A. Eremushkin, Alexandra M. Stepanova, Vsevolod N. Galkin, Alexander E. Ivanov, Saida A Akavova

“…To investigate the relationship between different rehabilitation programmes following cervical cancer surgery and return to work MATERIALS AND METHODS. …”
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Research on the supply-demand balance evaluation and driving mechanism of community public service facilities. by Jian Chen, Ying Fu, Shenglan Ma, Qiao Chen, Wanqing Zhang, Junlin Huang

“…This study takes 400 living circles in Changsha as samples and, based on the theory of "spatial equilibrium," applies CRITIC method, system coordination model, and geographic detector to systematically evaluate the "supply-demand" equilibrium of community-level public service facilities. …”
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A Single-Way Ranging Localization of AUVs Based on PSO of Outliers Elimination by Xinnan Fan, Zhongjian Wu, Jianjun Ni, Chengming Luo

“…Some simulation experiments are carried out to illustrate the performance of the proposed method compared with another localization algorithm.…”
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Perspectives of Nurse Leaders Regarding Time Management in Nursing: Qualitative Research by Ana Luiza Ferreira Aydoğdu

“…Results: Data were organized into five themes: (1) Factors that facilitate time management in nursing, (2) Factors that hinder time management in nursing, (3) Impairments to care due to inappropriate use of time, (4) Differences in relation to other health professions, and (5) Measures for optimizing time management in nursing. …”
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Dietitians and Nutritionists: Stigma in the Context of Obesity. A Systematic Review. by Franziska U C E Jung, Claudia Luck-Sikorski, Nina Wiemers, Steffi G Riedel-Heller

“…The aim of this article was to review the current state of quantitative research on weight-related stigma by dietitians and nutritionists.<h4>Method</h4>A systematic literature review was conducted in 2014 using PubMed, PsycINFO, Web of Science and Cochrane Library.…”
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Corner Reflector Plasmonic Nanoantennas for Enhanced Single-Photon Emission by Pedro Chamorro-Posada

“…A comprehensive numerical study of silver and gold corner reflector nanoantennas, employing the finite difference time domain method, is presented. The results demonstrate that a well-designed corner reflector can significantly enhance photon emission directivity while also substantially boosting the emission rate.…”
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Analysis measurements of millet collision coefficient of restitution for mechanized seeding. by Yifei Li, Wenqi Zhou, Shujuan Yi, Tao Chen, Dongming Zhang, Song Wang

“…A combination of bench and simulation tests validated the test results, showing no significant differences and confirming the method's viability for determining COR. …”
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Abstract 233: First‐line Techniques for Endovascular Therapy of Primary Distal medium Vessel Occlusion Stroke: A Matched Analysis by Mahmoud H. Mohammaden, Hend Abdelhamid, Mohamed R. Dohiem, Stavros G. Matsoukas, Johanna Fifi, Bradley J. Gross, Alhamza R. Al‐Bayati, Marta Olive‐Gadea, Marc Rodrigo‐Gisbert, Andre Monteiro, James M. Siegler, Mudassir Farooqui, Santiago Ortega‐Gutierrez, Gustavo J. Cortez, Ricardo A. Hanel, Ameer E. Hassan, Thanh N. Nguyen, Mohamed A. Salem, Jan‐Karl Burkhardt, Peter Kan, Omar Tanweer, Ali Alaraj, Diogo C. Haussen, Adnan H. Siddiqui, Raul G. Nogueira

“…We aimed to compare the clinical and procedural outcomes among first‐line SR, CA and combined techniques in patients with primary DMVO. Methods This is a retrospective analysis of a prospectively maintained database from 14 comprehensive stroke centers in the US and Europe. …”
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