Study protocol for COVID-19 breakthrough infections and vaccine-induced immune response among a cohort of healthcare workers, Bangladesh. by Md Zakiul Hassan, Ahamed Khairul Basher, Mohammed Ziaur Rahman, Taufiqur Rahman Bhuiyan, Fahmida Chowdhury, Md Kamal Hossain, Aninda Rahman, Md Nazmul Islam, Lindsey M Duca, Susan Cornelia Kaydos-Daniels, Benjamin A Dahl, Firdausi Qadri, Nancy Ortiz

“…<h4>Background</h4>To optimize vaccination strategies, it is useful to detect breakthrough infections and assess vaccine effectiveness in programmatic use. …”
Get full text

Non-invasive MRI measurements of age-dependent in vivo human glymphatic exchange using magnetization transfer spin labeling by Dahan Kim, Yujia Huang, Jiaen Liu

“…These findings survived when the exchange metrics were compensated for potential atrophy-related dilution effect caused by variations in intra-voxel CSF volume. Conclusion: Optimized MT-based parenchyma spin labeling followed by CSF partial saturation measurement demonstrated feasibility of a noninvasive MRI approach to detect glymphatic water exchange between human brain parenchyma and CSF in vivo, with statistically significant findings of age-related differences in the exchange measures.…”
Get full text

Investigation of heavy metals adsorbed on microplastics in drinking water and water resources of Zabol by Mohammad Reza Rezaei Kahkha, Jamshid Piri, Ali Faghihi-Zarandi, Massoud Kaykhaii

“…Future studies should explore the health effects of MPs and HMs, optimize sampling methods, and focus on long-term monitoring under diverse environmental conditions to address this emerging issue comprehensively.…”
Get full text

Developing a Smart Sensing Sock to Prevent Diabetic Foot Ulcers: Qualitative Focus Group and Interview Study by Jenny Corser, Irantzu Yoldi, Neil D Reeves, Pete Culmer, Prabhuraj D Venkatraman, Giorgio Orlando, Rory Peter Turnbull, Paul Boakes, Eric Woodin, Roger Lightup, Graham Ponton, Katherine Bradbury

“…MethodsThis qualitative study combined semistructured interviews and a focus group alongside a participant advisory group that was consulted throughout the study. …”
Get full text

Predicting the potential distribution areas of Leptotrombidium rubellum under current and future climate change by Qunzheng Mu, Qunzheng Mu, Fengfeng Li, Wenyu Li, Wenyu Li, Xiaoxia Wang, Mingyuan Tang, Kehan Chen, Yihao Jiang, Jingqi Liu, Shirong Zhang, Qiyong Liu, Chuan Wang

“…The results may facilitate a transition from passive to proactive vector monitoring.MethodsFifty-seven potential influencing factors were evaluated. …”
Get full text

Comparison of the Blood–Brain Barrier Penetration Ability and Anti-Neuroinflammatory Activity of Chromones in Two Types of Agarwood by Mengyuan Yang, Yanan Yuan, Jingfan Wei, Yifei Pei, Yuanfei Niu, Yifan Zhao, Xiangying Kong, Zhijie Zhang

“…It further investigated the absorption and brain distribution characteristics of these components in rats and their neuroprotective effects mediated through anti-neuroinflammatory pathways. <b>Methods</b>: This study confirmed, through ITS2 barcoding and chloroplast genome analysis, that both the ordinary and Qi-Nan agarwood are derived from <i>Aquilaria sinensis</i>. …”
Get full text

Presence of toxin-producing bacterial pathogens and associated risk factors in neonatal diarrhea of piglets on commercial sow farms in Vietnam by Duy Tien Do, Tram Thi Ngoc Ngo, Huong Dieu Vu, Nhat Minh Duong, Sittikorn Traiyarach, Danh Cong Lai, Joaquin Miguel Escuder

“…Key virulence genes detected included LT (35.96%), alpha toxin (95.61%), and toxin A (20.17%). …”
Get full text

Exploring the neuromagnetic signatures of cognitive decline from mild cognitive impairment to Alzheimer's disease dementiaResearch in context by Sinead Gaubert, Pilar Garces, Jörg Hipp, Ricardo Bruña, Maria Eugenia Lopéz, Fernando Maestu, Delshad Vaghari, Richard Henson, Claire Paquet, Denis-Alexander Engemann

Get full text

Impact of Nasal Anatomical Variation Subtype on Surgical Outcomes for Rhinogenic Contact Point Headache by Salvatore Lavalle, Annalisa Pace, Giuseppe Magliulo, Mario Lentini, Jerome Rene Lechien, Christian Calvo-Henriquez, Federica Maria Parisi, Giannicola Iannella, Antonino Maniaci, Daniela Messineo

“…This study aimed to clarify the correlation with nasal anatomical variation detected by CT and RCPH treatment outcomes. <b>Methods:</b> A prospective cohort study was conducted on 90 RCPH patients undergoing surgery or medical therapy. …”
Get full text

Prediction of Therapeutic Response and Prognosis in Ovarian Cancer Patients With Plasma Circulating Biomarkers by Haixia Cheng, Guangwen Yuan, Leilei Liang, Tiantian Wang, Jiarun Zhu, Hongying Yang, Zhendiao Zhou, Pei Wang, Qianqian Song, Yuchen Jiao, Mei Liu, Lingying Wu

“…ABSTRACT Background To assess whether changes in TP53 mutations and copy number alterations (CNA) in plasma circulating tumor DNA (ctDNA) can predict treatment response and prognosis in platinum‐resistant recurrent ovarian cancer (PROC) patients. Methods Fifty‐seven PROC patients were recruited. …”
Get full text

Comparison of prognostic factors that affect the survival of patients with metachronous and synchronous metastases of renal cell carcinoma by D. V. Semenov, R. V. Orlova, V. I. Shirokorad, S. V. Kostritsky, S. G. Grigoriev, Yu. S. Korneva

“…To identify prognostic factors affecting survival rates in patients with synchronous and metachronous renal cell carcinoma metastases.Materials and methods. A retrospective analysis of 934 patients with mPCC treated in the period 2006 to 2020 was performed, of which 319 (34.2%) patients were assigned to the intermediate prognosis group, and 388 (41.5%) to the unfavorable prognosis group. …”
Get full text

Associations Between the Polymorphisms in the Coding Sequence of SLCO1B1 and Blood Lipid Levels Before and After Treatment by Atorvastatin in the Chinese Han Adults with Dyslipidem... by Chen C, Tian Y, Jia F, Feng M, Zhang G, Li Q, Zhang Y, Sun N, Hu S, Ji Z

“…This study endeavors to evaluate the relationship between polymorphisms in the coding sequence (CDS) of SLCO1B1 gene and blood lipid levels before and after atorvastatin treatment among the Chinese Han adults with dyslipidemia.Patients and Methods: A total of 165 Chinese Han adults undergoing atorvastatin therapy were enrolled in this study and followed up quarterly. …”
Get full text

Recombinant Hydrophobic Polypeptide MBAY Loaded Into SPION-Exosome Realizes Sustained-Release to Improve Type 2 Diabetes Mellitus by Zong X, Xiao S, Xia H, Guo D, Wu J, Zhuang M, Rao L

“…Therefore, in our study, the transmembrane hydrophobic structure of the exosome signature protein CD81 was fused with BAY 55-9837 to obtain MBAY with sustained-release capability.Methods: MBAY was fabricated via genetic engineering, and the dissociation constant (Kd) was determined to assess its affinity for vasoactive intestinal peptide receptor type 2 (VPACII). …”
Get full text

Intraoperative Intraluminal Endoscopy in the Surgical Treatment of Patients with Esophageal Diverticula of Various Localization by A. L. Shestakov, M. V. Khrustaleva, M. E. Shahbanov, N. A. Bulganina, T. T. Bitarov, I. A. Boeva, A. T. Tskhovrebov, I. A. Tarasova, O. V. Rykov, I. M. Selivanova, A. A. Bezaltynnykh

“…To improve the results of surgical treatment of patients with esophageal diverticulum of various localization using intraoperative intraluminal endoscopy. Materials and Methods: The Department of Surgery of the Esophagus and Stomach, the Petrovsky National Research Centre of Surgery, has accumulated a large experience in treating diverticulosis patients. …”
Get full text

Pitfalls in the diagnosis of apparent homozygous mutations: two cases of IL10RA deficiency inflammatory bowel disease and a literature review by Xiu Shi, Ziqing Ye, Lai Qian, Wenhui Hu, Ye Yang, Chunmeng He, Zhiheng Huang, Bingbing Wu, Ying Huang

“…Methods Peripheral blood samples were collected from two patients and their parents. …”
Get full text

A multi-view CNN model to predict resolving of new lung nodules on follow-up low-dose chest CT by Jingxuan Wang, Xiaowen Zhang, Wei Tang, Marcel van Tuinen, Rozemarijn Vliegenthart, Peter van Ooijen

“…We evaluated the performance of a multi-view convolutional neural network (CNN) in distinguishing resolving and non-resolving new, intermediate-sized lung nodules. Materials and methods This retrospective study utilized data on 344 intermediate-sized nodules (50–500 mm3) in 250 participants from the NELSON (Dutch-Belgian Randomized Lung Cancer Screening) trial. …”
Get full text

Ameliorative Effect of Lacticaseibacillus paracasei Combined with Aerobic Exercise on Obesity in Mice by ZHAO Hanyi, CAO Sijia, QI Jianing, BIAN Yanqing, ZHANG Jiaqi, GAO Yuqi, FENG Zhaoyang, SUN Wenjing, XUE Yuling, WANG Yanhong, PENG Liping

“…Objective: To investigate the effect of Lacticaseibacillus paracasei N1115 combined with aerobic exercise on improving glucose and lipid metabolism, inflammatory response, learning and memory capacity, intestinal morphology and intestinal flora diversity in obese mice. Methods: C57BL/6 mice were used to establish an obese mouse model by feeding them a high-fat diet. …”
Get full text

Influence of light quality on the profiling of metabolites and the status of Lactobacillus community in the phyllosphere of hydroponically grown ginseng by Nooruddin Bin Sadiq, Ji-Eun Lee, Muhammad Hamayun, Seda Nur Kabadayı, Na-Yun Park, Bokyung Lee, Ho-Youn Kim

“…Based on the potential of controlled environments to shape both plant and microbial responses, the impact of different light conditions on the phyllosphere microbiota is crucial for plant health and productivity. Methods This study evaluated two Korean ginseng varieties exposed to different LED light treatments in a hydroponic system. …”
Get full text

Neurocognitive and emotional long-term effects of COVID-19 infections in children and adolescents: results from a clinical survey in Bavaria, Germany by Julia Hauke-Gleißner, Irina Jarvers, Silke Jordan, Stephan Gerling, Michael Kabesch, Romuald Brunner, Stephanie Kandsperger

“…Methods We conducted an observational study involving 85 pediatric patients aged 12–17 years (M = 12.48, 61.2% female) who had confirmed COVID-19 infections and were experiencing persistent symptoms for at least 4 weeks. …”
Get full text

Psychotropic Drugs for Older Adults With Psychiatric Disorders Presenting to the Emergency Department: Prescription Patterns and Treatment Outcomes by Marianna Mazza, Marcello Covino, Francesco Maria Lisci, Caterina Brisi, Georgios D. Kotzalidis, Giuseppe Marano, Francesca Abate, Maria Benedetta Anesini, Gianluca Boggio, Michele Ciliberto, Valeria De Masi, Cecilia Falsini, Ester Maria Marzo, Sara Rossi, Maria Chiara Spera, Alberto Torresi, Benedetta Simeoni, Francesco Franceschi, Gabriele Sani

“…Methods During 2014 to 2023, 342 aged patients (35.96% men and 64.04% women; median age = 73 years, range 68–79 years) sought help at the ED of our hospital and required psychiatric consultation. …”
Get full text