PD-L1 and p53 expression in squamous cell carcinoma of the oropharynx depending on human papilloma virus status by D. Sh. Polatova, A. Yu. Madaminov, A. V. Savkin, A. I. Nurzhabov, N. K. Asamedinov, D. A. Ibragimova, R. R. Davletov, S. K. Nasirov

“…Easy testing, low cost, reliability, and high sensitivity of immunohistochemical analysis for p16INk4a allowed to widely use this method for Hpv status determination.Aim. To determine the association between programmed death-ligand 1 (pD-L1) and p53 expression and presence of indirect Hpv marker – p16INk4a – in patients with OSCC.Materials and methods. …”
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Prevalence and molecular characterisation of multi-drug resistant ST11 hypervirulent Klebsiella pneumoniae in a teaching hospital by Xue Li, Kai Ma, Xin Liu, Ping Cheng, Lailai Li, Yihui Chai, Mingle Cao, Yuqi Yang

“…Methods We conducted a retrospective analysis of 102 carbapenem-resistant CRKP strains. …”
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Parametric study and optimisation of supercritical extraction of Chlorella Vulgaris microalgae using Response surface methodology by Milap G. Nayak, Reena D. Gamit

“…Also, extraction involving SCCO2 and its optimisation involving the RSM method showed an effective and statistically sound method for algal oil extraction.…”
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Research on path planning for coal mine rescue robots by ZHU Hongbo, YIN Hongliang

“…This paper proposes a path planning method for coal mine rescue robots based on a Hierarchical Smooth Optimization Bidirectional A* guided dynamic window approach (HSTA*-G-DWA) algorithm. …”
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Radiomic study on preoperative multi‐modal magnetic resonance images identifies IDH‐mutant TERT promoter‐mutant gliomas by Haoyu Wang, Shuxin Zhang, Xiang Xing, Qiang Yue, Wentao Feng, Siliang Chen, Jun Zhang, Dan Xie, Ni Chen, Yanhui Liu

“…A diagnostic model (multilayer perceptron classifier) for detecting the IDHmut pTERTmut gliomas was trained using an automatic machine‐learning algorithm named tree‐based pipeline optimization tool (TPOT). …”
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The role of diffuse correlation spectroscopy and frequency-domain near-infrared spectroscopy in monitoring cerebral hemodynamics during hypothermic circulatory arrestsCentral Messa... by Alexander I. Zavriyev, BS, Kutlu Kaya, MS, Parisa Farzam, PhD, Parya Y. Farzam, BS, John Sunwoo, PhD, Arminder S. Jassar, MBBS, Thoralf M. Sundt, MD, Stefan A. Carp, PhD, Maria Angela Franceschini, PhD, Jason Z. Qu, MD

“…Conclusions: FDNIRS-DCS is able to detect changes in CBFi, SO2, and CMRO2i with intervention and can become a valuable tool for optimizing cerebral protection during HCA.…”
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CVT-HNet: a fusion model for recognizing perianal fistulizing Crohn’s disease based on CNN and ViT by Lanlan Li, Ziyue Wang, Chongyang Wang, Tao Chen, Ke Deng, Hong’an Wei, Dabiao Wang, Juan Li, Heng Zhang

“…In addition, the MobileNetV2 with Coordinate Attention mechanism and encoder modules are optimized to improve the precision of detecting anal fistulas. …”
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Exploring Attention in Depth: Event-Related and Steady-State Visual Evoked Potentials During Attentional Shifts Between Depth Planes in a Novel Stimulation Setup by Jonas Jänig, Norman Forschack, Christopher Gundlach, Matthias M. Müller

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U-Net-based VGG19 model for improved facial expression recognition by Xiaohu ZHAO, Jingyi ZHANG, Mingzhi JIAO, Lixun XIE, Lanfei WANG, Weiqing SUN, Di ZHANG

“…These innovations contribute to achieving state-of-the-art performance in facial expression recognition, making the proposed method an important contribution to advancing computer vision and deep learning. …”
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A humanized anti-MSLN×4-1BB bispecific antibody exhibits potent antitumour activity through 4-1BB signaling activation and fc function without systemic toxicity by Da-yan Zhang, Zhi-hua Zhang, Wen-ting Liu, Wei-ming Zhou, Peng-fei Zhou, Juan-juan Wei, Xue-jing Dai, Xiao-li Zeng, Yu-qiong Zhou, Han-wang Li, Heng Zhang, Ao-lin Shen, Lian-sheng Cheng, Guo-dong Shen, Yi-fu He

“…Therefore, a safe and efficient immunostimulatory molecule is urgently needed for cancer immunotherapy. Methods A novel anti-MSLN×4-1BB bispecific antibody (bsAb) was generated via antibody engineering, and its affinity and activity were detected via enzyme-linked immunosorbent assay (ELISA), flow cytometry, and T-cell activation and luciferase reporter assays. …”
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Balancing the benefits and risks of colchicine use among patients with atherosclerotic cardiovascular disease: an umbrella review of meta-analyses of randomised controlled trialsRe... by Rui-Han Bao, Na Zhao, Xiao-Feng Jiang, Zi-Han Cong, Jun Liu, Long-Dan Kang, Yu-Han Chen, Jia-Nan Sun, Wei-Yi Xing, Jia-Xin Liu, Xue-Li Bai, Hai-Chen Lv, Jing-Ying Zhao, Qi-Peng Ma, Ting-Ting Gong, Qi-Jun Wu

“…Publication bias was detected via funnel plot asymmetry or Egger’s test. …”
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Impact of Improved Sanitation Standard Operating Procedures on Microbial Populations at Three Tree Fruit Packing Facilities by M. Laura Rolon, Marysabel Mendez Acevedo, Priscilla Sinclair, Dumitru Macarisin, Luke F. LaBorde, Jasna Kovac

“…Total aerobic bacteria were quantified using a standard plate count method, and Listeria spp. and L. monocytogenes concentration was quantified using a Most Probable Number method. …”
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MEGA PROTAC, MEGA DOCK-based PROTAC mediated ternary complex formation pipeline with sequential filtering and rank aggregation by Sadettin Y. Ugurlu, David McDonald, Ramazan Enisoglu, Zexuan Zhu, Shan He

“…Once candidate PPCs are selected, a grid search method is used separately for translation and rotation. …”
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Dynamic Monitoring of Goaf Stress Field and Rock Deformation Driven by Optical Diber Sensing Technology by Jing Chai, Zhe Yan, Yibo Ouyang, Dingding Zhang, Jianfeng Yang, Gaoyi Yang, Chenyang Ma

“…Addressing the critical technological needs for the real-time monitoring of stress distribution in mining areas, a new method for inverting goaf pressure using distributed optical fiber monitoring data is proposed. …”
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The acceptability of blood spot screening and genome sequencing in newborn screening: a systematic review examining evidence and frameworks by Duncan Chambers, Susan Baxter, Anastasios Bastounis, Katherine Jones, Burak Kundakci, Anna Cantrell, Andrew Booth

“…Background Population-wide newborn blood spot screening programmes are a successful public health intervention used to detect whether the baby is at risk of certain rare conditions, with the aim of earlier diagnosis and provision of optimal care and treatment. …”
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Letter from editor by Carlos A. Vargas

“…From Morocco, a study aimed to evaluate geostatistical methods for delimitation of anomalies detected in the phosphatic series of Sidi Chenane found that the exponential model is the best one to represent the spatial variability of their geoelectric data; models of the geology were successfully obtained from geostatistical method, which help mapping the phosphate deposit inclusions and the estimations of phosphate reserves were improved and better constrained. …”
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STUDY OF BIOCHEMICAL MARKERS’ CONTENT OF BONE TISSUE METABOLISM IN THE ORAL LIQUID OF PATIENTS WITH GENERALIZED PERIODONTITIS by I.V. Vozna, A.V. Samoilenko, S.V. Pavlov

“…The object and research methods. There were examined 178 patients. The study group consisted of 126 patients with generalized periodontitis of initial (8), I (32), II (68), and III (18) severity levels, chronic course who are working in hazardous conditions of the "Dniprospetsstal" plant in Zaporizhzhya. …”
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Adaptive data embedding for curved spaces by Anoop Praturu, Tatyana O. Sharpee

“…Application of the method to COVID sequences revealed that viral evolution leaves the dimensionality of the space unchanged but produces a logarithmic increase in curvature, indicating a constant rate of information acquisition optimized under selective pressures. …”
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Integration of Artificial Neural Network in a IEEE 5 BUS System by T. L. Makosso, A. Almaktoof, K. Abo-Al-Ez

“…In the context of Artificial Neural Networks (ANNs), the Levenberg-Marquardt (LM) algorithm is an extensively utilized optimization method. It is generally used to train feedforward neural networks, especially when those networks have several layers and complicated optimization problems. …”
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Clustering of unknown protocol messages based on format comparison by ZHANG Mingyuan, LIU Xiaolei, WU Xiaohu, ZHANG Xiaojian

“…In this paper, we propose an Unknown Protocol Packet Clustering MethodBased on Format Matching (CUPFC), which introduces the enhanced Barcos paradigm, defines Token Format Distance (TFD) and Message Format Distance (MFD) to represent the format similarity of Token and packets, and introduces Jaccard distance and an optimized sequence alignment algorithm to calculate them. …”
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