Combined thrombus fragmentation and catheter-directed thrombolysis in the treatment of pulmonary thromboembolism in high- and moderate-risk patients by V. Dimitrova, B. Vodenicharova, D. Dimitrov, P. Krastev

“…Aim: To evaluate the safety and efficacy of CBT in high- and moderate-risk patients with acute PE as an initial treatment strategy at one-year follow-up. Material and methods: For the period of May 2021- 2024, a total of 35 patients with acute PE were treated in our clinic. …”
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Glucocorticoids and mineralocorticoids in hair: facilitating accurate diagnosis of adrenal-related endocrine disorders by Bianca Heyns, Rialet Pieters, Marietjie Aletta Stander, Stephen Lawrence Atkin, Amanda Cecilia Swart, Amanda Cecilia Swart

“…Cortisol was 1.5-fold higher than cortisone in accordance with the circulatory cortisol/cortisone relationship.ConclusionsThe novel extraction method optimized steroid measurement, showing the consistency of measurement for glucocorticoids, cortisol and cortisone, and mineralocorticoids, corticosterone, 18-hydroxycorticosterone, and aldosterone. …”
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Elucidating metabolite and pH variations in stroke through guanidino, amine and amide CEST MRI: A comparative multi-field study at 9.4T and 3T by Kexin Wang, Licheng Ju, Guanda Qiao, Yajie Liang, Yihan Wu, Chengyan Chu, Joshua Rogers, Yuguo Li, Suyi Cao, Valina L. Dawson, Ted M Dawson, Piotr Walczak, Jiadi Xu

“…CEST contrasts were extracted using the Polynomial and Lorentzian Line-shape Fitting (PLOF) method. Both pMCAO and tMCAO models were utilized to examine the B1-dependence patterns and pH sensitivity of the different CEST contrasts in ischemic lesions compared to contralateral region. …”
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Egyptian pediatric kidney transplantation: highlights on post-transplant follow-up and management of complications by the Egyptian Pediatric Clinical Practice Guidelines Committee... by Bahia Moustafa, Neveen A. Soliman, Ihab Shaheen, Ahmed Badr, Fatma M. Atia, Mohamed K. El Hatw, Engy Adel Mogahed, Mona EL-Ghamrawy, Khaled El Khashab, Noha Shaheen, Mohamad G. Shouman, Abeer Selim, Magdy El-Sharkawy, Tarek Abd El Azeem, Mohamad Esmat, Manal Salman, Bedeir Ali-El-Dein, Mona Abdel Rahim, Muhamed A. El-Hadedy, Moatasem Elsayed Ghoneim, Mai S. Korkor, Tarek E. I. Omar, Yasser Amer, Ashraf Abdel Baky, On Behalf of Egyptian Pediatric Clinical Practice Guideline Committee

“…Aim/objectives This national adapted guideline aims to frame evidence-based post-transplant recommendations adopted or adapted from EB source guidelines to optimize post-transplant patient care. Methods Our guideline is evidence based adapted from four national and international source guidelines with permissions [KDIGO 2020, RA/BTS 2022–2018, EAU 2018] that were appraised with AGREE II instrument tool. …”
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In Vitro Evaluation of the Antibacterial Effect and Influence on the Bacterial Biofilm Formation of Glutamic Acid and Some Structural Analogues by Octavia-Laura Oancea, Cristina Nicoleta Ciurea, Anca Delia Mare, Adrian Man, Ruxandra Stefanescu, Aura Rusu

“…The influence on biofilm formation was assessed by the crystal violet method, reading the optical densities (ODs) by spectrophotometry. …”
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Scanner-specific optimisation of automated lesion segmentation in MS by David R. van Nederpelt, Giuseppe Pontillo, Mar Barrantes-Cepas, Iman Brouwer, Eva M.M. Strijbis, Menno M. Schoonheim, Bastiaan Moraal, Bas Jasperse, Henk-Jan M.M. Mutsaerts, Joep Killestein, Frederik Barkhof, Joost P.A. Kuijer, Hugo Vrenken

“…The aim of this study was to investigate the within-scanner repeatability and between-scanner reproducibility of lesion segmentation tools in pwMS across three different scanners and examine their accuracy compared to manual segmentations with and without optimization. Methods: 30 pwMS underwent a scan and rescan on three MRI scanners. …”
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Identification and validation of a novel autoantibody biomarker panel for differential diagnosis of pancreatic ductal adenocarcinoma by Metoboroghene O. Mowoe, Metoboroghene O. Mowoe, Hisham Allam, Joshua Nqada, Marc Bernon, Karan Gandhi, Sean Burmeister, Urda Kotze, Miriam Kahn, Christo Kloppers, Suba Dharshanan, Zafirah Azween, Pamela Maimela, Paul Townsend, Eduard Jonas, Jonathan M. Blackburn, Jonathan M. Blackburn

“…Autoantibodies (AAbs) in principle make attractive biomarkers as they arise early in disease, report on disease-associated perturbations in cellular proteomes, and are static in response to other common stimuli, yet are measurable in the periphery, potentially well in advance of the onset of clinical symptoms.MethodsHere, we used high-throughput, custom cancer antigen microarrays to identify a clinically relevant autoantibody biomarker combination able to differentially detect PDAC. …”
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Newborn Intravenous Injection of Liposomal CRISPR/Cas9 Complex Has No Incidence of Off-Targets or Tumors in Mice by Vinícius Monteagudo, Larissa Cristina Barbosa Flores, Melaine Lopes, Flavia Nathiely Silveira Fachel, Giselle Martins, Marina Siebert, Willian da Silva Carniel, Tuane Nerissa Alves Garcez, Helder Ferreira Teixeira, Ursula Matte, Roberto Giugliani, Guilherme Baldo, Édina Poletto, Roselena Silvestri Schuh

“…This study investigated whether the hydrodynamic administration of liposomal CRISPR/Cas9 complexes (LCs) in newborn mice induces off-target events or tumors. <b>Methods</b>: Liposomes were obtained through microfluidization. …”
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Novel Epigenetics Control (EpC) Nanocarrier for Cancer Therapy Through Dual-Targeting Approach to DNA Methyltransferase and Ten-Eleven Translocation Enzymes by Risa Mitsuhashi, Kiyoshi Sato, Hiroyoshi Kawakami

“…Herein, we demonstrate the potential of the EpC carrier in HCT116 human colon cancer cells to upregulate tumor suppressor gene expression and rapidly achieve cell cycle arrest. Methods: PLGA core nanoparticles were prepared by the W/O/W double emulsion method. …”
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Prognostic factors in patients with hepatocellular cancer with progression after liver transplantation by I. A. Dzhanyan, M. S. Novruzbekov, O. D. Olisov, V. V. Breder

“…The probability of progression of hepatocellular cancer after orthotopic liver transplantation within the first two years is about 75% and about 10% is detected after the fourth year. Progression of hepatocellular cancer remains the main factor limiting the life expectancy of patients after orthotopic liver transplantation.The aim of the study: to evaluate the results of antitumor treatment of patients with hepatocellular cancer progression after liver transplantation.Materials and methods. …”
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Recommendations of the Russian League Against Epilepsy (RLAE) on the use of magnetic resonance imaging in the diagnosis of epilepsy by G. N. Avakyan, D. V. Blinov, A. A. Alikhanov, E. M. Perepelova, V. A. Perepelov, S. G. Burd, A. V. Lebedeva, G. G. Avakyan

“…Introduction. The MRI method has revolutionized the diagnosis of epilepsy. …”
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A multi-level classification model for corrosion defects in oil and gas pipelines using meta-learner ensemble (MLE) techniques by Adamu Abubakar Sani, Mohamed Mubarak Abdul Wahab, Nasir Shafiq, Kamaludden Usman Danyaro, Nasir Khan, Adamu Tafida, Arsalaan Khan Yousafzai

“…Machine learning techniques are useful in detecting corrosion defects, ensemble methods that combine multiple classifiers offer better predictive accuracy. …”
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A systematic review of the literature in relation to the theoretical knowledge base for the-Clinical-functional research by evaluation including the modern apparatus modality of fu... by Irina Raluca Petcu, Gelu Onose

“…NIRS/fNIRS is a non-invasive brain imaging method and is a suitable technique for detecting brain activity during motor dynamics. …”
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Measurement of contact pattern displacement of hypoid gears with optical thermal camera by Stefan GERDHENRICHS, Manuel OEHLER, Daniel BUSCHMANN, Robert Heinrich SCHMITT, Oliver KOCH

“…To address these challenges, this paper presents a method for measuring the deflection of hypoid gear sets by an evaluation of thermographic contact pattern. …”
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ANALYSIS AND MINIMIZATION OF THE RISKS OF HARMFUL DEPENDENCIES IN THE PROCESS OF CONTINUOUS INTEGRATION AND IMPLEMENTATION OF SOFTWARE CODE by Danil N. Alekseev, Renat M. Khamitov

“…To prevent these threats, various protection methods are proposed, such as controlling access to private packages, using automated tools for monitoring and checking dependencies, and implementing machine learning systems to detect suspicious packages. …”
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Development of Aeromonas salmonicida Vaccine Carrier Expressing G Protein of Infectious Hematopoietic Necrosis Virus by Yatong GAO, Zhipeng WANG, Ye GAO, Ming ZHU, Jie LI

“…A PBS control was prepared using the same method. Rainbow trout were immunized by intraperitoneal injection with a vaccine or phosphate buffered saline (PBS) control. …”
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Caracterización de resistencia de las cuchillas centrales para molinos azucareros. // Resistance characterization of sugar mills central knives. by J. Hernández de la Torre, A. García Domínguez, E. Nápoles Padrón

“…Finally, the authors make suggestions<br />for a future study of wear and for the weight and volume optimization of the investigated object.</p><p><br />Key words: Central knife, sugar mills, finite element method.…”
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Volatile Organic Compounds in Honey: Tandem Mass Spectrometry as Tool to Quantitate Priority VOCs by Evangelia N. Tzanetou, Efstathia Vousaxaki, Kyriaki Machera, Jozef van der Steen, Konstantinos M. Kasiotis

“…The HS conditions were optimized, and method validation criteria were extensively investigated. …”
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Thyroid-stimulating hormone and thyroid hormone levels in association with occupational hazards in male coal miners by Yingshi DAI, Yingjun CHEN, Yingqi LUO, Yanhui LIU, Liuquan JIANG, Fan YANG, Gaisheng LIU, Qingsong CHEN

“…ObjectiveTo investigate the associations between occupational hazard exposure and thyroid-stimulating hormone (TSH) and thyroid hormone levels in male coal mine workers. MethodsA cross-sectional study design was adopted. …”
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Preclinical Study of a Dual-Target Molecular Probe Labeled with ⁶⁸Ga Targeting SSTR2 and FAP by Huanhuan Liu, Xiaojun Zhang, Yue Pan, Jingfeng Zhang, Hui Wen, Cong Zhang, Xiaodan Xu, Guangyu Ma, Ruimin Wang, Jinming Zhang

“…Methods: Using the somatostatin analog TATE and quinoline-based compound FAPI-46 as raw materials, we designed and synthesized ⁶⁸Ga-labeled TATE-46. …”
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