Economic assessment of energy consumption and greenhouse gas emissions from wheat production in Ardabil provience by Jabraeil Taghinazhad, َAdel Vahedi, Fayaz Ranjbar

“…The being Independent on agricultural productions lead to take more attention to modern methods and the objective of all these methods is increasing the performance with the efficient use of inputs or optimizing energy consumptions in agricultural systems. …”
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Electron paramagnetic resonance spectroscopy for analysis of free radicals in zebrafish. by Mitra Sabetghadam Moghadam, Eli Wiens, Sébastien Gauvrit, Ramaswami Sammynaiken, Michelle M Collins

“…Spin trapping with nitrone compounds like 5,5-dimethyl-1-pyrroline N-oxide (DMPO) is a method commonly employed for detecting free radicals. …”
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Scientific geovisualization of the dynamics of Sargassum dispersion and landfall in the Caribbean, based on satellite imagery and numerical forecasts. by Francisco Javier Osorno-Covarrubias, Jorge Prado Molina, Gabriela Gómez-Rodríguez, Uriel Mendoza, Stéphane Couturier

“…Further steps, beyond the scope of this study, would be required, including optimization of the remote sensing technique, improvement of the transport simulation methods, and an experimental framework for accuracy assessment. …”
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Mitochondrial morphology in fertile and infertile men: image processing and morphometric analysis of the sperm midpiece by María Fernanda Skowronek, Santiago Pietroroia, Gabriel de Cola, Mauricio Ramos, Diego Silvera, Gabriela Casanova, Federico Lecumberry, Adriana Cassina, Adriana Cassina, Rossana Sapiro, Rossana Sapiro

“…However, despite established links between abnormal sperm morphology and pathology, mitochondrial abnormalities in sperm remain relatively understudied.MethodsIn this study, we employed computational image analysis and fluorescence labelling to quantitatively assess morphometric changes in the sperm midpiece and correlate these findings with mitochondrial ultrastructure in fertile and infertile men.ResultsOur results revealed a significant increase in midpiece area, width, and roundness in sperm from men with teratozoospermia. …”
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Effects of osthole on renal tubular epithelial cell injury and Nrf2/HO-1 signal pathway induced by high glucose，hypoxia and reoxygenation by Han Ming-yue, Ding Yue-mei, Song Kai-yun

“…ObjectiveTo explore the effects of osthole on renal tubular epithelial cell damage and Nrf2/HO-1 signal pathway induced by high glucose，hypoxia and reoxygenation.MethodsHuman renal tubular epithelial cells HK-2 were cultured in high-glucose medium and subjected to hypoxia-reoxygenation treatment to establish a cellular model.CCK-8 experiment was utilized for detecting the effects of 0，10，20，40，80，160 µg/ml osthole on its growth and screen the optimal concentration.HK-2 cells were divided into control，model，osthole （80 µg/ml），ML385 （Nrf2 inhibitor，20 nmol/ml） and osthole （80 µg/ml）+ML385 （20 nmol/ml） groups.Except for control group，the other groups were induced for establishing cellular models.After high glucose，hypoxia and reoxygenation，CCK-8 experiment was utilized for detecting cellular viability in each group.Kits were employed for measuring the levels of reactive oxygen species （reactive oxygen species，ROS），glutathione peroxidase （GSH-Px），malondialdehyde （MDA），lactate dehydrogenase （LDH），tumor necrosis factor-α （TNF-α），interleukin-6 （IL-6） and interleukin-1β （IL-1β）； Immunofluorescence for detecting the expression of Nrf2/HO-1 pathway protein； Western blot for detecting the expression of Nrf2/HO-1 pathway protein.ResultsCompared with control group，HK-2 cellular viability （100±0 <italic>vs</italic> 43.47±6.14），cellular GSH-Px level （9.53±1.64 <italic>vs</italic> 3.25±0.32） and cellular Nrf2 protein （1.78±0.30 <italic>vs</italic> 0.89±0.12） were markedly down-regulated in model group （all <italic>P</italic>&lt;0.05）； the levels of ROS （1.13±0.17 <italic>vs</italic> 6.52±1.03） and TNF-α spiked markedly （all <italic>P</italic>&lt;0.05）.Compared with model and osthole + ML385 groups，HK-2 cellular viability （43.47±6.14，44.83±7.06 <italic>vs</italic> 87.76±9.42），cellular GSH-Px level （3.25±0.32，3.27±0.38 <italic>vs</italic> 9.07±1.78） and cellular Nrf2 protein （0.89±0.12，0.90±0.18 <italic>vs</italic> 1.74±0.26） rose in osthole group （<italic>P</italic>&lt;0.05）； ROS （6.52±1.03，6.47±0.96 <italic>vs</italic> 1.59±0.21） and TNF-α declined （both <italic>P</italic>&lt;0.05）； HK-2 cellular viability （43.47±6.14，44.83±7.06 <italic>vs</italic> 24.80±3.79），cellular GSH-Px level （3.25±0.32，3.27±0.38 <italic>vs</italic> 0.88±0.15） and cellular Nrf2 protein （0.89±0.12，0.90±0.18 <italic>vs</italic> 0.30±0.05） decreased in ML385 group （all <italic>P</italic>&lt;0.05）； ROS （6.52±1.03，6.47±0.96 <italic>vs</italic> 9.76±2.02） and TNF-α increased （all <italic>P</italic>&lt;0.05）.ConclusionOsthole can up-regulate the expression of Nrf2/HO-1 signaling pathway protein，suppress ROS and inflammatory factors production induced by high glucose，hypoxia and reoxygenation，thereby relieving oxidative stress and inflammation and lessening the damage of renal tubular epithelial cells.…”
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Prevalence of Onchocerca lupi in shelter dogs from an endemic region of the Southwestern USA by Maureen A. Kelly, Erin Clarke, Hassan Hakimi, Christine M. Budke, Guilherme G. Verocai

“…Methods This probe-based qPCR was optimized with a detection threshold of 0.33 pg for DNA of an adult female O. lupi. …”
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Genomic Characterization of Carbapenemase-Producing Enterobacteriaceae from Clinical and Epidemiological Human Samples by Alexander Tristancho-Baró, Laura Eva Franco-Fobe, Monica Pilar Ariza, Ana Milagro, Ana Isabel López-Calleja, Blanca Fortuño, Concepción López, Miriam Latorre-Millán, Laura Clusa, Rosa Martínez, Carmen Torres, Antonio Rezusta

“…This study analyses CPE trends at a tertiary hospital in Spain from 2021 to 2023, aiming to optimize personalized medicine. <b>Methods</b>: CPE isolates were the first isolate per patient, year, species, and carbapenemase from January 2021 to December 2023. …”
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Sex and racial differences in prevalence and clinical characteristics of people living with LDLR and PCSK9 familial hypercholesterolemia genetic variants: Data from the All of Us R... by Jeffery Osei, Alexander C. Razavi, Arshed A. Quyyumi, Danny J. Eapen, Yan V. Sun, Muin J. Khoury, Laurence Sperling

“…Further targeted efforts, including increased genetic testing, are needed to improve FH detection and optimize treatment, particularly in racial and ethnic minority groups where LLT use remains inadequate.…”
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Sagittal Plane Kinematic Deviations and Spatio-Temporal Gait Characteristics in Children with Idiopathic Toe Walking: A Comparative Analysis Using Statistical Parametric Mapping by Rocio Pozuelo-Calvo, Almudena Serrano-Garcia, Yolanda Archilla-Bonilla, Angel Ruiz-Zafra, Manuel Noguera-Garcia, Kawtar Benghazi-Akhlaki, Miguel Membrilla-Mesa, Carla DiCaudo, Jose Heredia-Jimenez

“…This study aims to evaluate spatio-temporal and sagittal plane kinematic differences between children with ITW and typically developing peers using Statistical Parametric Mapping (SPM). <b>Methods</b>: A cohort of 30 children with ITW and 30 typically developing peers aged 6–12 years participated in this study. …”
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Diagnostic Performance of Artificial Intelligence in Chest Radiographs Referred from the Emergency Department by Julia López Alcolea, Ana Fernández Alfonso, Raquel Cano Alonso, Ana Álvarez Vázquez, Alejandro Díaz Moreno, David García Castellanos, Lucía Sanabria Greciano, Chawar Hayoun, Manuel Recio Rodríguez, Cristina Andreu Vázquez, Israel John Thuissard Vasallo, Vicente Martínez de Vega

“…We assessed the concordance between the AI system and the resident, noted the frequency of doubtful cases for each category, identified how many were considered positive by the GS, and assessed variables that AI was not trained to detect. Methods: We conducted a retrospective observational study analyzing chest X-rays from a sample of 784 patients referred from the ED at our hospital. …”
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Mass Media Exposure and Cervical Cancer Screening in Rural Sub‐Saharan Africa: A Multi‐Country Cross‐Sectional Analysis by Alex Bawuah, Vicky Q. Wang, Khadijat Adeleye, Edward Kwabena Ameyaw, Sanni Yaya

“…This study aimed to examine the prevalence of cervical cancer screening in SSA and to identify factors associated with screening uptake, with a specific focus on the influence of mass media among rural women. Methods The analysis utilized data from the Demographic and Health Surveys (DHS) conducted in 11 SSA countries, encompassing responses from 72,565 rural women of reproductive age (15–49 years). …”
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Association Between Shift Work and Acute Coronary Syndrome According to Alcohol Intake and Smoking by Seok-Jin Ryu, Sun-Min Kim, Hyun-Yi Kook, Eun-Young Park, Eujene Jung

“…This study examines how smoking and alcohol intake may influence the effect of shift work on ACS risk, indicating a complex interaction among these factors in individuals engaged in shift work. <i>Materials and Methods</i>: This investigation utilized data from the Korean Genome and Epidemiology Study (KoGES). …”
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Evaluation of Self-Regulating Doped Ferrite Nanoparticles with Glucose, Chitosan, and Poly-Ethylene Glycol Coatings for Hyperthermia and Dual Imaging by Negri A, Conti A, Milan E, Forlin E, Gherlinzoni F, Morana G, Gottardi M, Matteazzi P, Speghini A, Bongers A, Marzola P

“…The NPs were assessed for their physicochemical attributes, magnetic fluid hyperthermia (MFH) efficacy, dual-imaging capabilities in Magnetic Resonance Imaging (MRI) and Magnetic Particle Imaging (MPI), cytocompatibility, and cellular uptake.Methods: Physicochemical characterization was conducted using Fourier-transform infrared spectroscopy (FTIR), dynamic light scattering (DLS), and zeta potential measurements. …”
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Dry Eye Epidemiology in Patients before Refractive Operations by S. N. Sakhnov, S. V. Yanchenko, A. V. Malyshev, Y. A. Kalantaevskaya, R. A. Ismaylova, E. M. Ehieva, M. V. Grishenko, I. V. Gorbunova, O. F. Ozhug, O. A. Klokova

“…Conclusion: Raising the awareness of ophthalmologists about the prevalence of early DE manifestations in patients before refractive surgery will help optimize the detection of this pathology. The obtained data on the structure of DE clinical and pathogenetic variants and the etiological prerequisites can serve as a basis for the development of therapy. …”
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Elevated CD4⁺/CD8⁺ ratio and D-dimer as diagnostic biomarkers for Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis versus infectious mononucleosis in children: a re... by Yun Cheng, Wenjia Tong, Wangqiang Li, Yuanyuan Duan, Jingjing Jin, Biquan Chen

“…Abstract Objective To identify potential diagnostic biomarkers distinguishing Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis (EBV-HLH) from infectious mononucleosis (EBV-IM) in pediatric patients using a retrospective case-control design. Methods This study enrolled a total of 160 pediatric patients, including 132 with Epstein-Barr virus-associated infectious mononucleosis (EBV-IM) and 28 with EBV-associated hemophagocytic lymphohistiocytosis (EBV-HLH). …”
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Advances in key technologies for the management, restoration, development, and utilization of coal mining subsidence areas by Zhuanghan MENG, Yutao WANG, Yanzhe TIAN

“…Their management, restoration, development, and utilization play a significant role in ecological security, food security, and energy transformation. MethodsThis study aims to address the unresolved and emerging issues in the management of coal mining subsidence areas. …”
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Marcadores dermatoglíficos y su relación con el perfil neuromuscular en deportistas colombianos de alto rendimiento (Dermatoglyphic markers and their relationship with the neuromu... by Carlos Alberto Ramos Parraci, Brayan Esneider Patiño-Palma, Carlos Ándres Wheeler-Botero

“…Abstract. Introduction: the detection of talents in the sports field is one of the most important aspects, which is based on the identification of the capacities, factors or psychological and social influences that are part of a high-performance athlete, therefore, the model of digital impressions leads to a more appropriate choice of sports specialization, with the perspective of optimizing individual talent. …”
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Genetic analyses and molecular associations of FSHR and GH genes for semen traits in Egyptian buffalo by Abdelfatah R. Zaghloul, Maher H. Khalil, Mahmoud M. Iraqi, Amin M. S. Amin, Ibrahim Abousoliman, Ayman G. EL Nagar

“…Identifying genetic markers linked to semen traits can thus enhance breeding programs and optimize artificial insemination strategies. The objectives of this study were to estimate variance components and heritability. estimating the breeding values (EBVs), plotting the genetic and phenotypic trends and detection of the molecular genetic associations of FSHR and GH genes using PCR–RFLP with semen traits comprising ejaculate volume (EV), sperms motility (SM), live sperms (LS), abnormal sperms (AS) and sperms concentration (SC) in Egyptian buffalo. …”
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DYNAMICS OF PROAND ANTI-INFLAMMATORY PROSTAGLANDINS IN CASES OF GENERALIZED PERIODONTITIS ACCOMPANIED BY DIFFERENT TYPES OF REACTIVITY OF THE BODY by Yu.Yu. Yarov, Yu.I. Silenko

“…The aim of this research was to study the dynamics of proand anti-inflammatory prostaglandins (F2α and E2) in the blood of patients with generalized periodontitis accompanied by normo-, hyperand hyporeactivity of the body after patch surgery. Materials and methods of research. 216 people aged 45 between 55 years old with the diagnosis of generalized periodontitis were examined. …”
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Predictive Modeling of Acute Respiratory Distress Syndrome Using Machine Learning: Systematic Review and Meta-Analysis by Jinxi Yang, Siyao Zeng, Shanpeng Cui, Junbo Zheng, Hongliang Wang

“…The findings will provide evidence-based insights to support the development of more accurate and effective ARDS prediction tools. MethodsWe performed a search across 6 electronic databases for studies developing ML predictive models for ARDS, with a cutoff date of December 29, 2024. …”
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