Impact of a pharmacist driven antimicrobial stewardship program on inpatient antibiotic consumption in a Chinese Tertiary Hospital: a 5-year retrospective study by Can Qian, Ting Yuan, Fuyong Zhang, Shiyuan Gou, Chunmei Jiang, Xuebing Chen, Ya Huang, Xiaolin Zhao, You Du, Chenglong Li, Yangyun Han, Huaiyu Su

“…Pharmacists play a critical role in AMS due to their combined management functions and professional expertise.ObjectiveTo investigate the impact of a Pharmacist-Driven Antimicrobial Stewardship program on the consumption of antibiotics in a hospital.MethodsUnder the support of a hospital top-level design, we implemented a Pharmacist-Driven Antimicrobial Stewardship program led by pharmacists and involving multiple disciplines. …”
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Preterm preeclampsia screening and prevention: a comprehensive approach to implementation in a real-world setting by Stefania Ronzoni, Shamim Rashid, Aimee Santoro, Elad Mei-Dan, Jon Barrett, Nanette Okun, Tianhua Huang

“…This study assesses the feasibility of implementing preterm preeclampsia screening and prevention by leveraging information from our current aneuploidy screening program in a real-world setting with geographic separation clinical site and laboratory analysis site. Methods A prospective cohort study involved pregnant individuals undergoing nuchal translucency scans between 11 and 14 weeks. …”
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Real-time intestinal perfusion assessment for anastomotic site selection using laser speckle contrast imaging: Verification in a porcine model by Danique J.I. Heuvelings, Mahdi Al-Taher, Joost Calon, Manish Chand, Laurents P.S. Stassen, Tim Lubbers, Kevin P. Wevers, Luigi Boni, Nicole D. Bouvy, Wido Heeman

“…Therefore, we explored the efficacy and feasibility of a new laser speckle contrast imaging system to assess real-time intestinal perfusion. Methods: Three gradually perfused porcine small bowel loops were created, and five senior surgeons were asked to assess the perfusion differences based on laser speckle contrast images using PerfusiX-Imaging®. …”
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Chlorhexidine and benzalkonium chloride: promising adjuncts in combating multidrug resistant Klebsiella pneumoniae in healthcare settings by Amal F. Makled, Azza Z. Labeeb, Heba M. Moaz, Asmaa S. Sleem

“…Antimicrobial susceptibility was determined using the disc diffusion method. Minimum inhibitory concentrations (MICs) of chlorhexidine and benzalkonium chloride were measured via agar dilution. …”
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A protocol for a pilot randomised controlled trial of a Tailored Intervention for people with moderate-to-severe Chronic Obstructive Pulmonary Disease and Co-morbidities delivered... by Richard Lowrie, David Anderson, Aziz Sheikh, Jane Moir, Andrew McPherson, Bethany Stanley, Gillian Cameron, Lynda Attwood, Donald Noble, Elaine Rankine, Jennifer Anderson, Nicola Greenlaw, Fiona Hughes, Emma McIntosh, Samuel Owusu Achiaw, Caitlin Jones, Frances S. Mair

“…In addition, findings from the economic and process evaluations along with information obtained on the proposed quantitative efficacy outcomes inform on the sample size required for a subsequent definitive RCT will help inform on future research. Methods We describe methods for a multicentre pilot RCT, with parallel economic and qualitative process evaluations of TICC PCP. …”
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Microwave Reflectometry for Online Monitoring of Metal Powder Used in Laser Powder Bed Fusion Additive Manufacturing by Farzaneh Ahmadi, Reza Zoughi

“…While promising, this investigation represents an initial step in the long journey toward optimizing millimeter-wave methods for integration into real-world LPBF AM systems.…”
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Relevance of Preoperative Vessel Mapping and Early Postoperative Ultrasonography in Predicting Arteriovenous Fistula Failure in Chronic Kidney Disease Patients by Shikhar Gupta, Mehtab Ahmed, Sayema, Azam Haseen, Saif Quaiser

“…Introduction: The increasing prevalence of chronic kidney disease (CKD), coupled with advancements in the diagnosis and treatment of renal diseases and improvements in life expectancy, has led to a greater number of patients requiring hemodialysis. The preferred method of vascular access for hemodialysis is AV fistula formation; however, it is associated with a high rate of failure. …”
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Droplet microfluidic screening to engineer angiotensin-converting enzyme 2 (ACE2) catalytic activity by Evelyn F Okal, Philip A. Romero, Pete Heinzelman

“…Conclusions This work demonstrates the potential of droplet microfluidics for therapeutic peptidase engineering, offering a robust and accessible method to optimize enzyme properties for clinical applications.…”
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Automatic Plant Watering System Using RTC And Rain Sensor by Haris Yuana, Zunita Wulansari, Mukh Taofik Chulkamdi

“…RTC is used to set the watering schedule based on a predetermined time, while the rain sensor serves as an automatic controller to stop watering when rain is detected. The system development method involves designing well-integrated hardware and software. …”
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Pathological complete response after monotherapy with immune checkpoint inhibitors for bifocal colon cancer in a patient with lynch syndrome and situs inversus totalis: a case repo... by Jun Feng, Wenbo Niu, Juan Zhang, Yuanyi Ding, Zheng Li, Jianfeng Zhang, Baokun Li, Chenhui Li, Feifei Wang, Guiying Wang, Guiying Wang, Guiying Wang, Bin Yu

“…Future studies should investigate the optimal timing of immunotherapy, combination treatment strategies, and methods to mitigate immune-related toxicities. …”
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Prognostic significance of combined PCPE-1 and α-fetoprotein for hepatocellular carcinoma by Ruhua Zhang, Wanqi Chen, Xuelan Peng, Zhiguang Zhang, Shangjiu Yang, Li Zhong

“…Immunohistochemistry was used to detect PCPE-1 levels in 155 HCC patients. The ROC curve was employed to determine the optimal cutoff value of PCPE-1. …”
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Management of Evans’ Syndrome in Pregnancy: A Case Report and a Narrative Review by Giulia Fontana, Micaela Fredi, Cecilia Nalli, Rossana Orabona, Brunetta Guaragni, Laura Picciau, Valeria Cancelli, Laura Andreoli, Sonia Zatti, Angela Tincani

“…Given its rarity, available data concerning the clinical course and optimal management in pregnancy are limited. <b>Methods</b>: We present the case of a 32-year-old woman who experienced ES during her first pregnancy. …”
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The Effect of Systemic Inflammation and Clinicopathologic Features on Survival in Malignant Pleural Mesothelioma: A Multicenter Analysis by Nadiye Sever, Sedat Yıldırım, Ali Fuat Gurbuz, Delyadil Karakaş Kılıç, Esra Zeynelgil, Yunus Emre Altintaş, Berivan Deniz Çimik, Yeşim Ağyol, Ali Kaan Güren, Pınar Erel, Erkam Kocaaslan, Burak Paçacı, Mustafa Alperen Tunç, Abdussamet Çelebi, Nazım Can Demircan, Selver Işık, Rukiye Arıkan, Murat Araz, Serdar Karakaya, Murat Sarı, Osman Köstek, İbrahim Vedat Bayoğlu

“…<i>Materials and Methods:</i> This retrospective, multicenter study included 217 patients diagnosed with MPM between January 2009 and March 2024. …”
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Global surveillance of circulating microRNA for diagnostic and prognostic assessment of acute myocardial infarction based on the plasma small RNA sequencing by Xiaomin Wang, Yaojun Lu, Ruiping Zhao, Bing Zhu, Jian Liu, Qiang Yue, Rina Wu, Shuwen Han, Yuanyuan Gao, Juan Chen, Jie Gong, Danna He, Teng Xu, Jianchao Ying

“…Differentially-circulated miRNAs were analyzed between each group. All detected circulating miRNAs were examined by ROC analysis and then LASSO dimension reduction to obtain an optimal panel for diagnosis of AMI. …”
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Brain glucose metabolism in patients with traumatic brain injury undergoing rehabilitation: a longitudinal 18F-FDG PET study by Valeria Pingue, Valeria Pingue, Irene Bossert, Daniela D’Ambrosio, Antonio Nardone, Antonio Nardone, Giuseppe Trifirò, Nicola Canessa, Nicola Canessa, Diego Franciotta

“…BackgroundMeasuring 18F-FDG PET-detected brain glucose uptake provides reliable information on metabolic tissue abnormalities, cells dysfunction, and neurovascular changes after traumatic brain injury (TBI).ObjectivesWe aimed to study the relationship between post-traumatic brain glucose metabolism and functional outcomes in the so far unexplored field of longitudinally 18F-FDG PET-monitored patients undergoing rehabilitation after moderate-to-severe TBI.MethodsFourteen patients consecutively admitted to our unit in the post-acute phase after TBI underwent 18F-FDG-PET scans performed before and 6 months after inpatient rehabilitation program. …”
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Complications of lung cancer radiation therapy and the preventive role of positron-emission tomography by O. Yu. Stoliarova, Yu. V. Dumanskyi, O. V. Syniachenko, Ye. D. Yehudina, O. O. Khaniukov

“…Materials and methods. 1071 patients with LC at the ages from 24 to 86 years (mean age 59 years) were observed (83 % of men and 17 % of women). …”
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Effects of cold-water immersion on health and wellbeing: A systematic review and meta-analysis. by Tara Cain, Jacinta Brinsley, Hunter Bennett, Max Nelson, Carol Maher, Ben Singh

“…<h4>Objective</h4>This systematic review and meta-analysis aimed to evaluate the psychological, cognitive, and physiological effects of CWI in healthy adults.<h4>Methods</h4>Electronic databases were searched for randomized trials involving healthy adults aged ≥ 18 years undergoing acute or long-term CWI exposure via cold shower, ice bath, or plunge with water temperature ≤15°C for at least 30 seconds. …”
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Productivity, activity of digestive and antioxidant enzymes of carp (Cyprinus carpio Linnaeus, 1758) as a result of the use of inulin in low-nutrient feeds by O. Deren, O. Dobrianska, M. Koryliak

“…At the end of the experimental feeding, the selected fish were analyzed for productive parameters, antioxidant and digestive enzyme activity using methods generally accepted in aquaculture. Findings. …”
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Determination of the Polyphenol Composition of Raspberry Leaf Using LC-MS/MS by Hind Mesfer S. Alkhudaydi, Esther Njeri Muriuki, Jeremy P. E. Spencer

“…This approach aimed to quantify polyphenols in the brew and identify optimal steeping times for maximum polyphenol release. …”
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Screening and Risk Analysis of Atrial Fibrillation After Radiotherapy for Breast Cancer: Protocol for the Cross-Sectional Cohort Study “Watch Your Heart (WATCH)” by Laura Saint-Lary, Baptiste Pinel, Loic Panh, Gaelle Jimenez, Julien Geffrelot, Youlia Kirova, Jeremy Camilleri, David Broggio, Marie-Odile Bernier, Corinne Mandin, Christelle Levy, Serge Boveda, Juliette Thariat, Sophie Jacob

“…MethodsWATCH is a cohort study that will include 200 patients over 65 years old, treated with RT for BC 5 years before inclusion and without a history of AF. …”
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