Ascitic ovarian cancer is an adequate preclinical model of carcinomatosis to study intraperitoneal chemoperfusion treatment by G. S. Kireeva, O. A. Belyaeva, K. Yu. Senchik, V. G. Bespalov, A. N. Stukov, E. A. Gubareva, M. A. Maydin

“…In our study, the model of peritoneal carcinomatosis in rats with ascitic ovarian cancer was used. material and methods. There were three groups of rats with ascitic ovarian cancer: 1 – the control group (n=15) having no treatment; 2 – rats receiving normothermic intraperitoneal chemoperfusion with cisplatin, 40 mg/kg (n=12); 3 – rats receiving hyperthermic intraperitoneal chemoperfusion with cisplatin, 20 mg/kg (n=14). …”
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Degradation of bisphenol A using a MOF@COF-modified polyacrylonitrile ultrafiltration membrane by Chloe G Hahn, Soraya P Malinga, Thollwana A Makhetha

“…This necessitates efficient removal methods due to a variety of limitations in conventional water treatment processes, such as harmful byproducts, saturation, and membrane fouling. …”
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Performance Analysis of Artificial Intelligence Models for Classification of Transmission Line Losses by Abraham O. Amole, Oluwagbemiga E. Ajiboye, Stephen Oladipo, Ignatius K. Okakwu, Ibrahim A. Giwa, Olamide O. Olusanya

“…Conventional approaches to analyzing power losses in electrical transmission networks have largely emphasized generic power loss minimization through the integration of loss-reducing devices such as shunt capacitors. However, achieving optimal power loss minimization requires a more data-driven and intelligent approach that transcends traditional methods. …”
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Prediction of type 2 diabetes mellitus using fasting plasma glucose and HbA1c levels among individuals with impaired fasting plasma glucose: a cross-sectional study in Thailand by Tullaya Sitasuwan, Raweewan Lertwattanarak

“…An HbA1c level ≥6.0% or FPG ≥5.9 mmol/L were the optimal cut-off thresholds for the prediction of the presence of T2DM. …”
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Predictive Value of a Noninvasive Serological Hepatic Fibrosis Scoring System in Cirrhosis Combined with Oesophageal Varices by Feiyue Zhang, Tong Liu, Pan Gao, Sujuan Fei

“…The aim of the study was to evaluate the predictive value of the four following scoring systems in cirrhosis combined with oesophageal varices: aspartate and platelet ratio index (APRI), aspartate aminotransferase-alanine aminotransferase ratio (AAR), FIB-4, and S index. Methods. A total of 153 patients with cirrhosis were categorized into groups with or without oesophageal varices. …”
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Acute Neurotoxicity in Children Treated for Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma: A 10-Year Single-Centre Experience by Izabela Kranjčec, Nada Rajačić, Tamara Janjić, Monika Kukuruzović, Filip Jadrijević-Cvrlje, Maja Pavlović, Jelena Roganović

“…Early recognition and timely management are essential for rapid recovery and optimal outcomes.…”
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Frequency of hemodynamic response to orthostatic stress in heart failure with reduced ejection fraction, associations with clinical blood pressure by D. N. Fedorova, A. E. Soloveva, M. Fudim, V. L. Galenko, A. V. Kozlenok, A. V. Berezina, S. V. Villevalde

“…To assess hemodynamic response to active standing test (AST) with beat-to-beat blood pressure (BP) monitoring, their association with office BP and symptoms of orthostatic intolerance in patients with heart failure (HF).Material and methods. Outpatient HF patients with documented  left ventricular ejection  fraction <40%, followed   up in a HF center  and receiving optimal medical therapy, underwent AST with beat-to-beat  non-invasive BP monitoring.Hemodynamic response was assessed according to the European Federation of Autonomic Societies criteria.Results. …”
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Diagnostic work-up in periprosthetic joint infections of the knee: can the albumin-to-globulin ratio be a screening tool? by Domenico De Mauro, Tiziana Ascione, Enrico Festa, Lucrezia Marasco, Filippo Leggieri, Sara Rosito, Matteo Innocenti, Edoardo Di Pace, Giovanni Balato

“…Furthermore, the diagnostic accuracy of the proposed threshold was evaluated. Materials and methods Between January 2020 and April 2022, patients with failed or painful knee arthroplasty who were admitted to a tertiary referral institution undergoing the standardized diagnostic protocol to identify those with a periprosthetic joint infection (PJI) were analyzed. …”
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A Novel Complex Networks Clustering Algorithm Based on the Core Influence of Nodes by Chao Tong, Jianwei Niu, Bin Dai, Zhongyu Xie

“…Next, the algorithm gets the final cluster structure after clustering the rest of the nodes in the network by optimizing method. Experiments on different datasets show that the clustering accuracy of this algorithm is superior to the classical clustering algorithm (Fast-Newman algorithm). …”
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3D-Printed microneedle assays for point-of-care applications by Haoyang Yan, Huibin Ma, Xin Jiang, Jintao Zheng, Mingxi Chen, Kayan Awawdeh, Xiaohong Jiang, Runzhi Zhou, Jiacheng Yu, Haotian Luo, Yue Jia, Zheng Liang, Weini Xin, Ester Segal, Keying Guo

“…Microneedle arrays (MNAs) offer a minimally invasive approach for point-of-care (POC) diagnostics, enabling biomarker detection in interstitial fluid (ISF) with reduced discomfort. 3D-printing technology has revolutionized MNAs fabrication, providing a cost-effective and customizable alternative to traditional methods. …”
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Protocol for genetic dissection of class switch recombination using genome-editing tools by Pengfei Dai, Tingting Liu, Dingpeng Yang, Yifeng Luo, Liu Daisy Liu, Xia Xie, Yafang Shang, Xiaojing Liu, Fei-Long Meng

“…Here, we present a protocol for inducing class switch recombination using base editors or CRISPR-Cas9. We provide optimized guide RNA (gRNA) sequences and describe steps for cytokine activation, electroporation, surface immunoglobulin detection, and data analysis. …”
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Predictive model for determining the indications for automated 3D ultrasound for screening patients at low risk of developing breast tumors by A. E. Garanina, A. V. Kholin

“…To develop indications for 3D ultrasound based on predictive screening models for patients with a low risk of developing breast tumors based on the identification of the most significant risk factors.Patients and methods. A retro-prospective clinical study has been conducted from February 2019 to May 2023. …”
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Effects of maternal feeding of clofibrate on hepatic fatty acid metabolism in suckling piglet by Jinan Zhao, Brandon Pike, Feng Wang, Lin Yang, Paige Meisner, Yanling Huang, Jack Odle, Xi Lin

“…The effective utilization of milk fat as primary energy is indispensably required. Methods Pregnant sows (n = 27) were randomly assigned into 3 treatments. …”
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Gravity-based microfiltration reveals unexpected prevalence of circulating tumor cell clusters in ovarian and colorectal cancer by Anne Meunier, Javier Alejandro Hernández-Castro, Nicholas Chahley, Laudine Communal, Sara Kheireddine, Newsha Koushki, Nadia Davoudvandi, Sara Al Habyan, Benjamin Péant, Anthoula Lazaris, Andy Ng, Teodor Veres, Luke McCaffrey, Diane Provencher, Peter Metrakos, Anne-Marie Mes-Masson, David Juncker

“…CTC clusters (cCTCs), even rarer, are of growing interest, notably because of their higher metastatic potential, but very difficult to isolate. Method We introduce gravity-based microfiltration (GµF) for facile isolation of cCTCs using in-house fabricated microfilters and 3D printed cartridges. …”
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Nutrients and Quality Aspects Characterizing <i>Ostrea edulis</i> Cultivated in Valli di Comacchio (Northern Italy) Across Different Seasons by Francesco Chiefa, Paola Tedeschi, Mirco Cescon, Valentina Costa, Elena Sarti, Manuel Salgado-Ramos, Noelia Pallarés, Natasha Damiana Spadafora, Leonardo Aguiari, Luisa Pasti

“…The antioxidant activity values differed between the two methods used (DPPH and photochemiluminescence assays); however, the oysters collected in June presented lower antioxidant capacity. …”
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Investigational approach to adenoviral conjunctivitis: comparison of three diagnostic tests using a Bayesian latent class model by Raja Sundaramurthy, Rahul Dhodapkar, Subashini Kaliaperumal, Belgode Narasimha Harish

“…Results: Adenovirus was detected in 54.8% (34/62) of cases by combination of all three methods. …”
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Achillea extracts elicit anti-diabetic neuropathic pain by modulating inflammatory cytokines by Ola Kbaydet, Maha Abou-Ela, Karim Raafat

“…Results and conclusion: The optimized and validated GC-MS method was developed to quantify the major EO components. …”
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A Hybrid Transfer Learning Framework for Brain Tumor Diagnosis by Sadia Islam Tonni, Md. Alif Sheakh, Mst. Sazia Tahosin, Md. Zahid Hasan, Taslima Ferdaus Shuva, Touhid Bhuiyan, Muhammad Ali Abdullah Almoyad, Nabil Anan Orka, Md. Tanvir Rahman, Risala Tasin Khan, M. Shamim Kaiser, Mohammad Ali Moni

“…The proposed system integrates advanced preprocessing techniques, an ensemble of pretrained deep learning models, and explainable artificial intelligence (XAI) methods to achieve high accuracy and reliability. …”
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Intestinal Cells-on-Chip for Permeability Studies by Marit Keuper-Navis, Hossein Eslami Amirabadi, Joanne Donkers, Markus Walles, Birk Poller, Bo Heming, Lisanne Pieters, Bjorn de Wagenaar, Adam Myszczyszyn, Theo Sinnige, Bart Spee, Rosalinde Masereeuw, Evita van de Steeg

“…Intestine-on-chip systems hold considerable promise as testing platforms, but several characteristics still require optimization and further development. Methods: An established intestine-on-chip model for tissue explants was adopted for intestinal cell monolayer culture. …”
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Preclinical studies of a PARP-targeted theranostic radiopharmaceutical for pancreatic cancer by Jie Gao, Jie Gao, Yuhao Wang, Ruoqi Wang, Mengya Liu, Mengya Liu, Hongliang Wang, Jianguo Li, Jin Du, Jin Du

“…ObjectiveThis study aims to improve the biodistribution of probes and enhance tumor targeting through 68Ga/177Lu-labeled optimized probes, thereby providing better tumor detection and assessment in PET imaging while also exploring their therapeutic effects on tumors.MethodsThe physicochemical properties of PARPi probes were optimized through polyethylene glycol (PEG) modification. …”
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