Development status and key technologies of deep-sea towing autonomous underwater vehicles by Guanyu LU, Tiedong ZHANG, Zhenglin LI, Dapeng JIANG, Ming LEI, Wanzhen LUO

“…Modeling flexible bodies is key to accurate analysis, and combining multi-body dynamics, finite element method (FEM), and computational fluid dynamics (CFD) methods is a future trend. …”
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Advancements in digital drilling technology for deep engineering: a review by Keqi Fan

“…Numerous researches devoted to adopting the digital drilling methods for the in-situ application of deep rock engineering. …”
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Exploring Bioinformatics Solutions for Improved Leishmaniasis Diagnostic Tools: A Review by Natáli T. Capistrano Costa, Allana M. de Souza Pereira, Cibele C. Silva, Emanuelle de Oliveira Souza, Beatriz C. de Oliveira, Luiz Felipe G. R. Ferreira, Marcelo Z. Hernandes, Valéria R. A. Pereira

“…Nevertheless, the diagnostic methods do eventually have limitations, and there is no established gold standard. …”
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Development of a Simple and Accurate Molecular Protocol Using 16SrRNA for Species-Specific Identification of <i>Achromobacter</i> spp. by Giulia Maria Saitta, Laura Veschetti, Rebecca Feletti, Angela Sandri, Marzia Boaretti, Paola Melotti, Maria Carelli, Maria M. Lleò, Giovanni Malerba, Caterina Signoretto

“…Thermal profiles were optimized, and qPCR was performed on serial bacterial DNA dilutions to determine the detection limit (LOD). …”
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Unveiling the Spatial Variation in Ecosystem Services Interactions and Their Drivers Within the National Key Ecological Function Zones, China by Tingjing Zhang, Quanqin Shao, Haibo Huang

“…We assessed and validated five key ES in the National Key Ecological Function Zones (NKEFZs) of China—net primary productivity (NPP), soil conservation (SC), sandstorm prevention (SP), water retention (WR), and biodiversity maintenance (BM). By integrating the optimal parameter geographical detector with constraint line methods, we further explored the complex responses of ES interactions to driving factors across different functional zones. …”
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The role of mutation testing in patients with chronic myeloid leukemia in chronic phase after imatinib failure and their outcomes after treatment modification: Single-institutional... by Puligundla Krishna Chaitanya, Karnam Ashok Kumar, Bala Stalin, Gundeti Sadashivudu, Maddali Lakshmi Srinivas

“…Imatinib dose hike to the failure cases resulted in optimal hematological response rates.…”
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Patients with Primary Malignant Retroperitoneal Tumor: Surgical Treatment Outcomes by D. V. Omelchenko, A. B. Vasin

“…Determining the most optimal tactics for the diagnosis and treatment of primary malignant retroperitoneal tumors is highly relevant today. …”
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Optimisation of the adaptive neuro-fuzzy inference system for adjusting low-cost sensors PM concentrations by Martina Casari, Piotr A. Kowalski, Laura Po

“…These methods are chosen as benchmarks owing to their established effectiveness in calibration procedures.We propose certain preprocessing steps for detecting and rectifying anomalies, alongside introducing two distinct data-splitting methodologies. …”
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Test-Retest Reliability of the Isometric Soleus Strength Test in Elite Male Academy Footballers by David Rhodes, Josh Jeffery, Daniel Brook-Sutton, Jill Alexander

“… # STUDY DESIGN Test-retest reliability single cohort study. # METHODS Thirty elite male footballers (age = 22.8±5.0 years, height = 180.0±0.08 cm, weight = 70.57±4.0 kg) performed the ISST, through three maximum 3-second hold efforts with one minute rest between repetitions and 48 hours between tests, in each test. …”
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Establishing translational performance standards for TB therapy using rifampicin-based regimens in a male and female high-burden murine model by Jason E. Cummings, Lisa Woolhiser, Barbara Graham, Gregory T. Robertson, M. Nurul Islam, Richard A. Slayden

“…Abstract Background Establishing efficacy benchmarks in preclinical tuberculosis (TB) models is essential for optimizing and prioritizing therapeutic regimens. However, standardized classification methods for comparing high-performing regimens are currently lacking. …”
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The safety of cyclosporine and tacrolimus in pediatric nephrotic syndrome patients: a disproportionate analysis based on the FAERS database by Yu Liu, Chong Yan, Yaowang Zhao, Sui Deng, Jiancheng Zu

“…We employed three signal detection methods—Proportional Reporting Ratio (PRR), Relative Reporting Ratio (RRR), and Reporting Odds Ratio (ROR)—to assess the risk of drug-related AEs. …”
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Rapid Determination of Fatty Acids in Ziziphi Spinosae Semen from Different Origins by Internal Extractive Electrospray Ionization Mass Spectrometry by Peng LIU, Ning WANG, Si-yu XIE, Le-ting WANG, Zhe-hao LIANG, Run-chen LAI, Man-man QIN

“…Researches have indicated that the medicinal value of Ziziphi Spinosae Semen is attributed to its abundant fatty acid components. In this study, a method of internal extractive electrospray ionization mass spectrometry (iEESI-MS) was established for simultaneous quantification of five fatty acids, including linoleic acid, oleic acid, linolenic acid, stearic acid, and palmitic acid in Ziziphi Spinosae Semen from various origins. …”
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Performance of malaria rapid diagnostic test, microscopy, polymerase chain reaction, and histopathology to diagnose malaria among pregnant and parturient women using peripheral, pl... by Aklilu Alemayehu, Ahmed Zeynudin, Joseph Beyene, Delenasaw Yewhalaw

“…Conclusion Diagnostic performance of RDT and microscopy was sub-optimal to detect Plasmodium infection among pregnant and parturient women. …”
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Linguistic Markers of Pain Communication on X (Formerly Twitter) in US States With High and Low Opioid Mortality: Machine Learning and Semantic Network Analysis by ShinYe Kim, Winson Fu Zun Yang, Zishan Jiwani, Emily Hamm, Shreya Singh

“…We also evaluated the predictive power of these linguistic features using machine learning and identified key thematic structures through semantic network analysis. MethodsWe collected 1,438,644 pain-related tweets posted between January and December 2021 using tweepy and snscrape. …”
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Optimasi Fuzzy C-Means dan K-Means Menggunakan Algoritma Genetika untuk Pengklasteran Dataset Diabetic Retinopathy by Muhammad Ezar Al Rivan, Steven Steven, William Tanzil

“…Retina disorder can be known from data extracted from eye image. Early detection conduct using clustering. These methods are Fuzzy C-Means and K-Means. …”
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Evaluation of a fermented palm kernel meal as a prebiotic for enhancing immune response in Indonesian red claw crayfish (Cherax quadricarinatus) by Diki Danar Tri Winanti, Hilma Nahwa Firdausi, Maulid Wahid Yusup, Putu Cinthia Delis, Agus Setyawan, Yeni Elisdiana, Hilma Putri Fidyandini, Muhammad Kholiqul Amiin, Ari Widodo

“…PO and SOD activities significantly increased on days 5 and 14, respectively, with optimal responses at the highest dietary FPKM inclusion. …”
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Determination of acylcarnitines in intact brain tumors using coated blade spray mass spectrometry (CBS-MS) by Joanna Bogusiewicz, Karol Jaroch, Jacek Furtak, Marcin Birski, Krystyna Soszyńska, Anna Majdańska, Agata Ryfa, Marek Harat, Barbara Bojko

“…Therefore, this study aimed to optimize and test the coated blade spray mass spectrometry (CBS-MS) method in analyzing potential biomarkers in brain tumor studies: acylcarnitine. …”
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[18F]F-FMISO and [18F]F-FLT PET/CT dual-nuclide imaging for in vivo prediction of drug resistance in pancreatic cancer by SUN Chenwei, HAI Wangxi, QU Qian, XI Yun

“…Objective·[18F]F-FMISO and [18F]F-FLT are specific PET imaging agents for detecting the hypoxia microenvironment and cell proliferation, respectively. …”
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Tissue gene expression analysis approach in a context of high technical and biological heterogeneity by Evan Bagley, Souvik Seal, Lauren R. Fanning, Jean-Sebastien Anoma, Tami Crawford, Benjamin G. Vincent, Elizabeth L. Barry, Martha J. Shrubsole, Erin Kirk, John A. Baron, Dale C. Snover, David N. Lewin, Todd A. Mackenzie, Xiaohua Gao, Melissa A. Troester, Alexander V. Alekseyenko, Kristin Wallace

“…Methods The approach incorporates a colon specific positive control gene set (11 genes) to minimize sample exclusions. …”
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Improving consistency in methane emission quantification from the natural gas distribution systems across measurement devices by J. Tettenborn, D. Zavala-Araiza, D. Zavala-Araiza, D. Stroeken, H. Maazallahi, H. Maazallahi, C. van der Veen, A. Hensen, I. Velzeboer, P. van den Bulk, F. Vogel, L. Gillespie, L. Gillespie, S. Ars, J. France, J. France, D. Lowry, R. Fisher, T. Röckmann

“…Currently, the most common method for emission quantification uses the maximum methane enhancement detected while crossing a methane plume. …”
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