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  1. 1

    4-WEEK OPEN-LABEL CONTROLLED RANDOMIZED COMPARATIVE STUDY OF THE INJECTABLE AND TABLETTED FORMULATIONS OF METHOTREXATE IN RHEUMATOID ARTHRITIS by Yu. V. Muravyev, L. N. Denisov, A. V. Alekseyeva, N. V. Muravyeva, E. L. Shakhramanova, K. A. Kasumova, D. A. Gukasyan, I. S. Dydykina, V. V. Lebedeva, E. L. Nasonov

    Published 2011-06-01
    “…Subjects and methods. A 24-week open-label controlled randomized comparative study evaluated the therapeutic and side effects of MTJ and methotrexate tablets in RA and clarified whether MTJ treatment might be continued if its tabletted formulation was discontinued because of adverse reactions. …”
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    Quantification of Metronidazole in Tablets: Combining Thin-Layer Chromatography in the GPHF-Minilab™ with Image Processing Using Open-Source ImageJ Software by Christopher L. Harmon, Sean Butts, Mary Elizabeth Sowers, Ed Bethea, David Jenkins

    Published 2024-10-01
    “…The USP Metronidazole Tablet high-performance liquid chromatography (HPLC) assay was used as the reference method. …”
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  3. 3

    Bioequivalence Analysis of Ondansetron Hydrochloride Tablets in Healthy Chinese Subjects: A Randomized, Open-Label, Two-Period Crossover Phase I Study by Caiyun Jia, Na Zhao, Haojing Song, Yiting Hu, Yufang Xu, Caihui Guo, Wanjun Bai, Zhanjun Dong

    Published 2024-10-01
    “…Twenty-six healthy subjects received one tablet of ondansetron under fasting conditions and 28 subjects received one under postprandial conditions. …”
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    Bioequivalence of China- and Germany-manufactured bisoprolol (Concor®) tablets in fasted and fed healthy Chinese participants: a randomized, open-label, two-way, crossover study by Hang Yin, Zhili Jin, Ran Li, Dandan Li, Lusha Wang, Ruihua Dong

    Published 2025-03-01
    “…BackgroundThe bioequivalence of Concor® (Merck Healthcare KGaA, Darmstadt, Germany), a bisoprolol-containing tablet, manufactured in China and Concor® tablets manufactured in Germany has not been previously reported.MethodsThis single-center, open-label, randomized, two-period, two-sequence, crossover trial (28 February 2023–19 May 2023) compared the pharmacokinetics and safety of bisoprolol 5-mg tablets manufactured in China (test product) with those of bisoprolol 5-mg tablets manufactured in Germany (reference product) in healthy Chinese adults under fasted and fed conditions. …”
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    Evaluating the pharmacokinetics and safety of blonanserin tablets and Lonasen®: a randomized, open-label, two-period, two-sequence, self-crossover phase I clinical trial by Bo Qiu, Bo Qiu, Haojing Song, Haojing Song, Xue Sun, Xue Sun, Congyang Ding, Congyang Ding, Runxuan Du, Wanjun Bai, Wanjun Bai, Zhanjun Dong, Zhanjun Dong

    Published 2025-01-01
    “…ObjectiveThis study evaluated the pharmacokinetic and safety profiles of generic and original blonanserin tablets under fasting and postprandial conditions, and the bioequivalence of two formulations to obtain sufficient evidence for abbreviated new drug application.MethodsA randomized, open-label, two-period, two-sequence, self-crossover bioequivalence study was conducted to assess the bioequivalence of the test and reference blonanserin tablets under fasting and postprandial conditions. …”
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    Bioequivalence study of ondansetron tablets by HPLC-MS by E. S. Stepanova, M. V. Ovcharov, S. S. Barsegyan, S. M. Nikonova, V. V. Shilov, V. V. Chistyakov

    Published 2014-04-01
    “…Within the cross, a single, open, randomized study with a week washout period, the two sequences has been studied bioequivalence of tablet forms two ondansetron 18 volunteers (8 mg dosage). …”
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    Pharmacokinetics and Bioequivalence of Two Formulations of Febuxostat 40-Mg and 80-Mg Tablets: A Randomized, Open-Label, 4-Way Crossover Study in Healthy Chinese Male Volunteers. by Zhu Luo, Feng Nan, Jia Miao, Zhihui Chen, Mei Li, Maozhi Liang

    Published 2016-01-01
    “…<h4>Unlabelled</h4>The present study aimed to investigate the pharmacokinetic properties of febuxostat in healthy Chinese male volunteers and evaluate whether the two formulations of febuxostat 40-mg and 80-mg tablets are bioequivalent. A randomized, open-label, 4-way crossover study was conducted in healthy Chinese male volunteers under fasting conditions. 24 eligible subjects were randomized in a 1:1:1:1 ratio to receive a single dose of test or reference formulation of febuxostat 40-mg or 80-mg tablet. …”
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    Transliterated Cuneiform Tablets of the Electronic Babylonian Library Platform by Yunus Cobanoglu, Jussi Laasonen, Fabian Simonjetz, Ilya Khait, Sophie Cohen, Zsombor Földi, Aino Hätinen, Adrian Heinrich, Tonio Mitto, Geraldina Rozzi, Luis Sáenz, Enrique Jiménez

    Published 2024-02-01
    “…As of the time of writing, the constantly growing dataset contains around 25,000 tablets with over 350,000 lines of transliterated text. …”
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    Evaluation of bioequivalence of two tablet forms of lisinopril in healthy volunteers by S. A. Altynbekov, G. A. Dzholdygulov, V. N. Seryakov, Y. M. Budach, O. E. Kurilo, N. I. Kuznetsova

    Published 2013-09-01
    “…Under cross, single, open, randomized trial with 1 week washout period, with two sequences of 18 volunteers studied bioequivalence coated tablets, two manufacturers of lisinopril (20 mg dose). …”
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    Bioequivalence study of tablet forms of risperidone, olanzapine and quetiapine in healthy volunteers by V. V. Pisarev, M. M. Ulyashova, K. A. Vdovin, N. I. Tiseyko

    Published 2013-04-01
    “…This article presents the results of three studies of bioequivalence tablet forms of atypical antipsychotics risperidone, olanzapine, and quetiapine produced by JSC «Northern Star», Russia and the corresponding original drugs risperidone, olanzapine and quetiapine. …”
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  12. 12

    Pharmaceutical evaluation of plantain peel pectin as a disintegrant in conventional tablets by Desmond A.B. Otu, Frederick W.A. Owusu, Mariam E. Boakye-Gyasi, Raphael Johnson, Marcel T. Bayor, Prince G. Acquah Jnr, Yayra Edzor-Agbo, Mary-Ann Archer

    Published 2025-05-01
    “…The hardness of all the tablets ranged between 5.57±0.15 kgF and 11.96±0.75 kgF, while the friability for all tablets was below 1%. …”
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    Application of <i>in vitro</i> studies to predict the pharmacokinetics of rivaroxaban tablets by A. V. Suvorova, P. A. Losenkova, Yu. V. Medvedev, E. A. Malashenko, K. K. Karnakova, N. S. Bagaeva, A. Yu. Savchenko, A. M. Poluyanov, I. E. Shohin

    Published 2024-09-01
    “…The clinical study of rivaroxaban tablets was a prospective, open-label, randomized, crossover, two-stage comparative study in two groups of volunteers with a single dose of drugs on the fast condition. …”
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    A randomized, open-label, multi-center, active-controlled phase II study comparing abiraterone acetate tablets (II), an improved formulation, versus originator abiraterone acetate in patients with metastatic castration-resistant prostate cancer by Xiaolin Lu, Tao Dai, Xue Chen, Bin Wu, Hui Chen, Jitao Wu, Dexin Yu, Huixin Ge, Jian Li, Houbao Huang, Tiwu Fan, Linzhong Cheng, Xiaoping Zhang, Xuepei Zhang, Xin Yao, Junli Wei, Zhenqiang Xu, Wenzeng Yang, Chaohong He, Jiexin Luo, Ling Guan, Bin Fu, Qilin Wang, Xiaofeng Chen, Yongdong Zhang, Benkang Shi, Bin Zheng, Yong Wang, Hong Luo, Guoqiang Chen, Huan Wang, Quanren Wang, Dingwei Ye

    Published 2025-05-01
    “…This multi-center, randomized, open-label, active-controlled phase II study compared the pharmacodynamics (PD), pharmacokinetics (PK), and safety of abiraterone acetate tablets (II) (AAT[II]), a new formulation of abiraterone acetate, and ZYTIGA®, the originator abiraterone acetate (OAA), in patients with metastatic CRPC. …”
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    Bioequivalence of bisoprolol, coated tablets 10 mg JSC «Chimpharm» Republic of Kazakhstan by Y. M. Budach, O. E. Kurilo, A. K. Sariev, D. A. Abaimov, M. V. Shiryaev, E. Y. Styrova, S. A. Altynbekov, G. A. Dzholdygulov, V. N. Seryakov, K. S. Altynbekov

    Published 2013-04-01
    “…Within the cross, a single, open, randomized study with 10 day washout period, the two sequences has been studied bioequivalence of tablet forms two bisoprolol 18 volunteers (10 mg dosage). …”
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    Comparative bioequivalence study of Pioglitazone tablets, 20 mg (JSC «Chimpharm», Kazakhstan) and Actos® Tablets, 30 mg («Eli Lilly Holdings, Takeda Global Research and Development... by A. K. Sariev, D. A. Abaimov, M. V. Shiryaev, E. Y. Styrova, S. A. Altynbekov, G. A. Dzholdygulov, V. N. Seryakov, Y. M. Budach, O. E. Kurilo

    Published 2013-09-01
    “…Within the cross, a single, open, randomized study with a two-week washout period, the two sequences has been studied bioequivalence of tablet forms two pioglitazone 18 volunteers (30 mg dosage). …”
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    Article