Point-Of-Care low-field MRI in acute Stroke (POCS): protocol for a multicentric prospective open-label study evaluating diagnostic accuracy by Mauro Silvestrini, Simona Sacco, Massimo Caulo, Simona Marcheselli, Carmine Marini, Sergio Lucio Vinci, Angelo Galante, Marco Colasurdo, Raffaele Ornello, Matteo Foschi, Stefano Necozione, Mario Muselli, Paola Olimpia Achard, Luciano Fratocchi, Marco Cavallaro, Gabriele Polonara, Laura Straffi, Luca Sorrentino, Enrico Franconi, Marcello Alecci

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Modelling of SDN switch with OpenFlow protocol in AnyLogic by I.A. Filippov, V.A. Volkov, K.I. Nikishin, E.I. Gurin

“…In order to solve this problem, software- defined networks (SDN) are used, the main component of which is switch with OpenFlow protocol. The purpose of the study is to model a SDN switch with OpenFlow protocol in AnyLogic, in order to obtain the transmission characteristics of SDN, experimentally evaluate these characteristics. …”

The Development of the Open Machine-Learning-Based Anti-Spam (Open-MaLBAS) by Isaac C. Ferreira, Marcelo V. C. Aragao, Edvard M. Oliveira, Bruno T. Kuehne, Edmilson M. Moreira, Otavio A. S. Carpinteiro

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Phase I trial on the safety of olprinone for low central venous pressure management aimed at haemorrhage control during open and laparoscopic hepatectomy: a study protocol by Katsuhiko Uesaka, Yuya Miura, Teiichi Sugiura, Ryo Ashida, Katsuhisa Ohgi, Mihoko Yamada, Shimpei Otsuka, Yoshiyasu Kato, Takuya Oyakawa, Eiji Ando, Sunao Tamai

“…Phosphodiesterase-3 (PDEIII) inhibitors such as milrinone have shown efficacy in managing low CVP and maintaining haemodynamic stability. …”
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Evaluating the Efficacy and Safety of 48-Week Low-Dose Dienogest Administration in Patients With Dysmenorrhea Caused by Endometriosis: Protocol for a Randomized, Open-Label, Parallel-Group Trial by Kyoko Kikuno, Ryuta Asada, Takuma Ishihara, Yoshimasa Bomoto, Saki Murase, Yoko Ueda, Tomomi Shiga, Yoh Hayasaki, Tatsuro Furui, Satoko Matsuzaki, Masahiko Takemura, Kazutoshi Matsunami, Makoto Kubo, Naoki Ito, Masanori Isobe, Ken-ichirou Morishige

“…MethodsThis randomized, open-label, parallel-group, dose-comparison, multicenter trial follows the SPIRIT (Standard Protocol Items: Recommendations for Interventional Trials) 2013 guidelines and is conducted at 6 centers in Japan. …”
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Efficacy and Safety of Low-Dose Lenvatinib and Toripalimab in Patients With Recurrent Platinum-Resistant Ovarian Cancer: Study Protocol of a Multicenter, Open-Label, Single-Arm, Phase II Clinical Trial by Su H, Shang X, Liu H, Wang Y, Yu Y, Xu Y, Jiang K, Feng F

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Tegoprazan and low- or high-dose amoxicillin dual therapy versus bismuth-containing quadruple therapy for eradication (TREAT): protocol for a multicenter, open-label, non-inferiority, randomized controlled trial by Yi Hu, Xin Xu, Cong He, Nian-Shuang Li, Yong Xie, Xu Shu, Nong-Hua Lu, Yin Zhu

“…The antibiotic resistance and the impacts of therapy on gut microbiota are also evaluated. Design: Study protocol for a multicenter, open-label, non-inferiority, randomized controlled trial. …”
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Low Communication-Cost PSI Protocol for Unbalanced Two-Party Private Sets by Jingyu Ning, Zhenhua Tan, Kaibing Zhang, Weizhong Ye

“…In this paper, we propose a low communication-cost PSI protocol designed specifically for unbalanced two-party private sets, aiming to enhance the efficiency of communication. …”
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Critical care service delivery across healthcare systems in low-income and low-middle-income countries: protocol for a systematic review by Srinivas Murthy, Teri Reynolds, Richard Lowsby, Neill KJ Adhikari, Andrew George Lim, Lia Ilona Losonczy, Michael S Jaung, Sojung Yi, Sean Kivlehan, Enrico Dippenaar, Marc Li Chuan L C Yang, P Andrew Stephens, Nicole Benzoni, Nana Sefa, Emily Suzanne Bartlett, Brandon Alexander Chaffay, Naeha Haridasa, Bernadett Pua Velasco, Caitlin A Contag, Amir Lotfy Rashed, Patrick McCarville, Paul D Sonenthal, Nebiyu Shukur, Abdelouahab Bellou, Carl Mickman, Adhiti Ghatak-Roy, Allison Ferreira

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Low-value clinical practices in adult traumatic brain injury: an umbrella review protocol by Belinda J Gabbe, Henry Thomas Stelfox, Patrick Archambault, François Lauzier, Fiona Lecky, Francois Lamontagne, Michaël Chasse, Pier-Alexandre Tardif, Lynne Moore, Imen Farhat, John Kortbeek, Paule Lessard-Bonaventure, Catherine Truchon, Alexis F Turgeon

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Evaluating low back pain through electrodermal activity: a systematic review protocol by Sergio Hernandez-Sanchez, Sergio Sebastia-Amat, Juan Tortosa-Martinez, Gema Sanchis-Soler, Juan Manuel Cortell-Tormo

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Core outcome set in paediatric sepsis in low- and middle-income countries: a study protocol by Niranjan Kissoon, Srinivas Murthy, Gavin Wooldridge

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Methods of assessment of diabetic retinopathy in low- and middle-income countries: a protocol for scoping review by John Ellis, Andrew Blaikie, Obaid Kousha, Luis Cunha Gil, Idayani Panggalo

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Enhancing provider–patient connection through low-effort interventions: a scoping review protocol by Tianjing Li, Vineet Chopra, Ben Harnke, Claire Brickson, Dagan Hammar, Amiran Baduashvili

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Preventive strategies for low anterior resection syndrome: a protocol for systematic review and evidence mapping by Yang Li, Quan Wang, Xin-Yu Zhang, Ke-Lu Yang, Xiao-Nan Liu, Rui-Shu Li, Shi-Qi Wang

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Open-radiomics: a collection of standardized datasets and a technical protocol for reproducible radiomics machine learning pipelines by Khashayar Namdar, Matthias W. Wagner, Birgit B. Ertl-Wagner, Farzad Khalvati

“…We used the BraTS 2020 open-source Magnetic Resonance Imaging (MRI) dataset to demonstrate how our proposed technical protocol could be utilized in radiomics-based studies. …”
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Healthy Lifestyle Program (HeLP) for low back pain: protocol for a randomised controlled trial by Steven J Kamper, Emma K Robson, Simon Davidson, Priscilla Viana da Silva, Amanda Williams, Rebecca K Hodder, Hopin Lee, Alix Hall, Connor Gleadhill, Christopher M Williams

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Obstetrical safety indicators for preventing hospital harms in low risk births: a scoping review protocol by Jeremy M Grimshaw, Jessica Reszel, Sandra I Dunn, Mark C Walker, Aislinn Conway

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Detection of pulmonary nodules: a clinical study protocol to compare ultra-low dose chest CT and standard low-dose CT using ASIR-V by Marie Ludwig, Emilie Chipon, Julien Cohen, Emilie Reymond, Maud Medici, Anthony Cole, Alexandre Moreau Gaudry, Gilbert Ferretti

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Metformin for low back pain: Study protocol for a randomised, double-blind, placebo-controlled trial by Yuan Z. Lim, Donna M. Urquhart, Yuanyuan Wang, Mahnuma Mahfuz Estee, Anita E. Wluka, Stephane Heritier, Flavia M. Cicuttini

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