CYTOKINES IN ANTERIOR EYE CHAMBER LIQUID: THEIR ROLE IN DEVELOPMENT OF SYSTEMIC IMMUNE RESPONSE TO OCULAR TISSUE ANTIGENS by I. G. Kulikova, O. S. Slepova, E. V. Denisova, L. A. Kovaleva, P. V. Makarov, D. N. Lovpache

“…The work is dedicated to studies of interrelations between the cytokine contents in the liquid from anterior eye chamber (AEC), and development of systemic immune response to ocular tissue antigens, described in terms of an anterior eye chamber-associated immune disturbance (ACAID phenomenon). …”
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Cognitive and Ocular Factors Jointly Determine Pupil Responses under Equiluminance. by Tomas Knapen, Jan Willem de Gee, Jan Brascamp, Stijn Nuiten, Sylco Hoppenbrouwers, Jan Theeuwes

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CHANGES IN GLUTATHIONE PEROXIDASE ACTIVITY IN CARDIAC TISSUES OF RATS IN RESPONSE TO MECHANICAL INJURY OF THE BLOOD-OCULAR BARRIER by O. N. Gulenko, A. A. Devyatkin, P. V. Boriskin, O. N. Pavlova, V. V. Leonov, R. G. Karimova

“…Mechanical eye injury and damage to the blood-ocular barrier cause inflammation resulting in oxidative stress,  which, in turn, triggers myocardial ischemia, since the heart's need for oxygen exceeds its supply. …”
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Association of systemic inflammatory biomarkers with ocular disease: a large population-based cross-sectional study by Xue Wang, Haitao Jiang, Can Zhang

“…Abstract Background The aim of this study was to explore the association of systemic inflammatory biomarkers (systemic immune-inflammation (SII) index and systemic inflammatory response index (SIRI)) with the prevalence of ocular disease in the general population of the United States (U.S.). …”
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A pH-Responsive Poly Beta-Amino Ester Nanoparticulate Thermo-Responsive PEG-PCL-PEG Hydrogel Dispersed System for the Delivery of Interferon Alpha to the Ocular Surface by Yosra Abdalla, Lisa Claire du Toit, Philemon Ubanako, Yahya Essop Choonara

“…This study focuses on the design of an injectable pH-responsive and protective nanoparticle system dispersed into a thermo-responsive hydrogel for site-specific sustained delivery of interferon alpha (IFN-α2b) in the treatment of ocular surface tumours. …”
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The clinical safety landscape for ocular AAV gene therapies: A systematic review and meta-analysis by Zishi Liu, Haoliang Zhang, Huixun Jia, Hong Wang, Zhonghe Huang, Yuhao Tang, Zilin Wang, Jing Hu, Xiaohuan Zhao, Tong Li, Xiaodong Sun

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Dataset combining EEG, eye-tracking, and high-speed video for ocular activity analysis across BCI paradigms by Eva Guttmann-Flury, Xinjun Sheng, Xiangyang Zhu

“…We introduce a large dataset capturing electroencephalogram (EEG) signals, eye-tracking, high-speed camera recordings, as well as subjects’ mental states and characteristics, to provide a multifactor analysis of eye-related movements. Four paradigms - motor imagery, motor execution, steady-state visually evoked potentials, and P300 spellers - are selected due to their capacity to evoke various sensory-motor responses and potential influence on ocular activity. …”
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Refining Parkinson’s syndrome symptom forecasting using incorporated ocular imaging and the SymptoSense model by V. Jayasudha, N. Deepa, Devi Thiyagarajan

“…Combining NLP and ocular imaging, this innovative approach is evaluated against benchmark models like Forward Maximal Matching, Backward Maximal Matching, Bi-directional Maximal Matching, Word Embeddings, Sentiment Analysis, and Term Frequency-Inverse Document Frequency. …”
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Measurement of Corneal Biomechanical Properties using Corneal Visualisation Scheimpflug Technology and Ocular Response Analyser in Healthy Saudi Female Adults: A Cross-sectional St... by Farah Maqsood, Noura Aldossari, Menwah Al Matrafi, Musarat Amina, Maram M Bawazir

“…The IOP, CCT, and the corneal biomechanical properties at the first applanation (time-T1, velocity-V1, length-L1, deformation amplitude-DA1), second applanation (time-T2, velocity-V2, length-L2, deformation amplitude-DA2), highest concavity (Highest Concavity Time-HCT, Highest Concavity Radius-HCR, Highest Concavity Deformation Amplitude-HCDA), and Peak Distance (PD) were evaluated by using Corneal Visualisation Scheimpflug Technology (CST) whereas, Ocular Response Analyser (ORA) was used for the comparison of biomechanical properties. …”
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Early expression of osteopontin glycoprotein on the ocular surface and in tear fluid contributes to ocular surface diseases in type 2 diabetic mice. by Ananya Datta, Xin Yi Li, Manshul Nagpaul

“…However, its specific roles in modulating ocular surface dynamics and immune responses in diabetes remain unexplored. …”
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Transient ocular hypertension remodels astrocytes through S100B. by Weiran Huang, Kenji Matsushita, Rumi Kawashima, Susumu Hara, Yuichi Yasukura, Kaito Yamaguchi, Shinichi Usui, Koichi Baba, Andrew J Quantock, Kohji Nishida

“…A mouse model of transient ocular hypertension (OHT) and an in vitro cell stretch model were established to mimic the pathological conditions of increased intraocular pressure and mechanical stress on cultured cells. …”
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Psychometric validation of the Chronic Ocular Pain Questionnaire (COP-Q) by Amy Findley, Brigitte J. Sloesen, Nicola Hodson, Agkreta Leventi, Ben Pascoe, Rob Arbuckle, Paul O’Brien, Christel Naujoks, Michela Montecchi-Palmer, Diana Plaza, Paul M. Karpecki, Pedram Hamrah

“…Abstract Background The Chronic Ocular Pain Questionnaire (COP-Q) is a newly developed patient-reported outcome (PRO) measure intended to assess symptoms and impacts associated with Chronic Ocular Surface Pain (COSP). …”
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Characteristics of ocular findings of patients with coronavirus disease 2019 in China by Shudan Wang, Jiaoyang Feng, Rui Zhu, Xin Jin, Yiheng Ding, Di Jin, Yu Guo, Hong Zhang

“…The anonymous survey collected information on demographics, systemic COVID-19 symptoms, ocular diagnosis and symptoms, comorbidities and disease history.ResultsA total of 2,405 survey responses were collected and the final analysis included individuals in the 335 COVID-19 positive group and 434 individuals in the COVID-19 negative group. …”
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Presumed ocular tuberculosis in a developed country: a descriptive retrospective analysis of patients from a tertiary health care centre in the United Kingdom by Mariam M. Boshra, Amira Stylianidies, Hitesh Agrawal

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Selective Laser Trabeculoplasty Outcomes in Phakic and Pseudophakic Patients: A Meta-Analysis by Rushil Kumbhani, Amanda Wong, Aretha Zhu, Paras Shah, Tristan Tham, Farihah Anwar, Daniel Zhu

“…Conclusions: Our pooled and subgroup analysis revealed no significant difference in SLT response between the two populations. …”
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NMR Spectroscopy of Human Eye Tissues: A New Insight into Ocular Biochemistry by Tomasz Kryczka, Edward Wylęgała, Dariusz Dobrowolski, Anna Midelfart

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Role of Janus Kinase (JAK) Inhibitor in Autoimmune Ocular Inflammation: A Systematic Review by Ji Wen, Huifang Hu, Menglin Chen, Hang Yang, Yi Zhao, Yi Liu

“…Different types of JAK inhibitors might be associated with different responses when used to treat ocular inflammation. Conclusions. …”
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Identification of a Novel Subtype of Ocular Hypertensive Eyes with the Lowest Risk of Progression Under Treatment by Asma Poursoroush, Vida Abedi, Xiaoqin Huang, Jiang Li, Alireza Vafaei Sadr, Amy L. de Jongh Curry, Louis R. Pasquale, Michael V. Boland, Chris A. Johnson, Siamak Yousefi

“…Among these, one cluster demonstrated a significantly better response to ocular hypotensive medication compared to the others. …”
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Prevalence of bacterial eye infections and multidrug resistance patterns among eye infection suspected patients in Ethiopia: a systematic review and meta-analysis by Mihret Tilahun, Alemu Gedefie, Bekele Sharew, Habtu Debash, Agumas Shibabaw

“…Abstract Background Bacterial eye infections are major global health issue in developing countries like Ethiopia, poor hygiene, limited healthcare infrastructure, and inadequate treatment options contribute to the increased burden of these infections, leading to significant ocular morbidity and potential blindness. Major bacterial pathogens, including Staphylococcus aureus, Haemophilus influenzae, Streptococcus pneumoniae, and Pseudomonas aeruginosa, are responsible for these infections. …”
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Systematic dissection of pleiotropic loci and critical regulons in excitatory neurons and microglia relevant to neuropsychiatric and ocular diseases by Yunlong Ma, Dingping Jiang, Jingjing Li, Gongwei Zheng, Yao Deng, Xuanxuan Gou, Shuaishuai Gao, Cheng Chen, Yijun Zhou, Yaru Zhang, Chunyu Deng, Yinghao Yao, Haijun Han, Jianzhong Su

“…Functionally, excitatory neuron-specific regulons were involved in axon guidance and synaptic activity, while microglia-specific regulons were associated with immune response and cell activation. In sum, these findings underscore the genetic link between psychiatric disorders and ocular diseases.…”
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