Is the Meibopatch Heated Pad Useful in Treating Patients with Meibomian Gland-Related Dry Eye Disease? – Assessing Tolerability, Acceptance, and Effectiveness by Bakhiet TE, Ansari AS, Williams GS, Awad MH, Thomas A

“…The ocular surface disease index (OSDI) questionnaire was utilized to evaluate symptoms both at baseline and following the four-week treatment period. …”
Get full text

Pathogenic mechanisms and molecular features of a novel UL2 gene-deficient duck enteritis virus endemic to China by Dan Yin, Yuehua Gao, Mingqing Xu, Jianhua Wang, Xiaofei Song, Zhen Li, Jianyun Peng, Min Kang, Bai Wei, Chengdong Yu, Yingjuan Qian, Yong-Sam Jung, Feng Hu, Junfeng Lv, Zhuoming Qin, Yufeng Li

“…Duck enteritis virus (DEV) was identified as the etiological agent responsible for an outbreak of morbidity and mortality in adult ducks on a farm in Jiangsu, China. …”
Get full text

Interruption of the visual cycle in a novel animal model induces progressive vision loss resembling Stargardts Disease by Fabiana Sassone, Catherine Estay-Ahumada, Michel J. Roux, Dominique Ciocca, Paola Rossolillo, Marie-Christine Birling, Janet R. Sparrow, Diego Montenegro, David Hicks

“…Non-invasive fundus imaging showed widespread photoreceptor loss, confirmed by ocular coherence tomography. Functional recording by single flash and flicker electroretinography showed significant decline in photopic (cone) light responses. …”
Get full text

Electroretinographic and Morphological Characterization of the Retina of Annexin A1 Knockout Mice by Rafael André da Silva, André Maurício Passos Liber, Luiz Philipe de Souza Ferreira, Francisco Manuel Moreno-Carmona, Diego Dias dos Santos, Monielle Sant’Ana, Marcelo Fernandes Costa, Dora Fix Ventura, Cristiane Damas Gil

“…Background/Objectives: The annexin A1 (AnxA1) protein has proven important in ocular disease homeostasis and holds great therapeutic promise. …”
Get full text

In vitro and in vivo regenerative processes resulting from the effect of experimental samples of synthetic polyvinyl formal based hydrogel implants by Yu.M. Samchenko F.D., A.P. Maletskyi, S.M. Dybkova, T.G. Gruzina, L.S. Rieznichenko, V.I. Podolska, L.O. Kernosenko, O.V. Artemov, T.P. Poltoratska, N.M. Zholobak, V.G. Kolesnichenko

“…Material and Methods: Scanning electron microscopy (SEM) analysis; Vero cell culture evaluation of in vitro regenerative processes by the wound-healing assay; evaluation of in vivo regenerative processes in the rabbit ocular and crest tissues resulting from the effect of experimental samples of synthetic PVF based hydrogel implants. …”
Get full text

Stratification of the Extent of Visual Impairment Identifies Sex-Specific Degenerative Changes in Retinal Structure and Function during Aging by Genea Edwards, Sean M. Riordan, Caitlin Buchholz, Marc Mardelli, Carlyn P. Euritt, Rodrigo Perez-Magnelli, Ariej Rafiq, Avery Engelmeyer, Peter Koulen

“…Background: Initial manifestations of neurodegenerative ocular conditions, including age-related macular degeneration (AMD) and glaucoma, often remain undetected in the early stages and can begin after the age of 50 years with the likelihood gradually increasing each year thereafter. …”
Get full text

Age-Related Macular Degeneration and Circadian Preference by Garces E, Slota K, Stewart MW, Guzman MP, Werninck NM, Castillo PR

“…While the disparity in survey responses between study participants and controls was generally not statistically significant, more study participants struggled with attending exercises between 7:00 and 8:00 in the morning compared to controls (45% vs 21%, P=0.02). …”
Get full text

Methylene Blue Reduces Electroretinogram Distortion and Ganglion Cell Death in a Rat Model of Glaucoma by Ronan Nakamura, Nicolás S. Ciranna, Juan C. Fernández, Rafael Peláez, Álvaro Pérez-Sala, Miriam Bobadilla, Juan J. López-Costa, César F. Loidl, Alfredo Martínez, Manuel Rey-Funes

“…We have shown that MB treatment can be effective in preventing physiological and morphological hallmarks of optic neuropathy in a model of ocular hypertension, which faithfully recapitulates human open-angle glaucoma. …”
Get full text

Effects of COVID-19 protective measures on the ophthalmological patient examination with an emphasis on gender-specific differences by Bernhard Steger, Antonia Osl, Reinhard Angermann, Christoph Palme

“…Objective In response to the COVID-19 pandemic, strict hygiene and containment measures have been instituted in the clinical ophthalmological examination to prevent virus transmission. …”
Get full text

Efficacy, safety and cost-effectiveness of methotrexate, adalimumab or their combination in non-infectious non-anterior uveitis: a protocol for a multicentre, randomised, parallel... by José Antonio Pinto, Alex Fonollosa, Ester Carreño, Maria Isabel Rodriguez, David Diaz-Valle, Diana Peiteado, Luis Rodriguez-Rodriguez, Miguel Cordero-Coma, Marta Tejera Santana, Lidia Cocho, Ana Belen Rivas, Amanda Lopez-Picado, Valentina Calamia, Felix M Francisco Hernandez, Angel Garcia-Aparicio, Javier Garcia-Gonzalez, Jose Juan Mondejar, Leticia Lojo-Oliveira, Llucí Martínez-Costa, Santiago Munoz, Beatriz Rodriguez-Lozano, Esperanza Pato, Elena Molina, Luis Alberto Tebar, Mara Albert Fort, Mayte Ariño Gutierrez, Pedro Arriola Villalobos, Joseba Artaraz Beobide, Antonio Atanes Sandoval, Jose Manuel Sanchez, Francisco Blázquez, Pablo Borges Deniz, Lara Borrego Sanz, Gabriela Bustamante Sanchez-Arnedo, Bruno Casco Silva, Ricardo Cuiña Sardiña, Almudena De Pablo Cabrera, Maria Del Mar Esteban Ortega, Patricia Fernandez Puente, Dalifer Dayanira Nuñez, Javier Garcia Bella, Sara Garcia Carazo, Luis Garcia Onrubia, Jose Maria Morales, Jose Antonio Fernandez, Vanesa Hernandez Hernandez, Inés Hernanz Rodriguez, Jose Maria Cantalapiedra, Ventura Hidalgo Barrero, Maria De Jovani Casano, Sara López Sierra, Virginia Lozano Lopez, Alfredo Madrid Garcia, Rosalia Mendez Fernandez, Pilar Nozal Aranda, Eugenio Perez Blazquez, Chamaida Plasencia Rodriguez, Sheila Recuero Diaz, Ignacio Robles Barrena, Esther Rodriguez Almaraz, Fayna Maria Gonzalez, Guadalupe Rodriguez Martinez, Fredeswinda Isabel Bueno, Ioana Ruiz Arruza, Beatriz Sanchez Marugan, Olga Sanchez Pernaute, Armelle Schlinker Giraud, Alvaro Seijas Lopez, Patricia Simon Alonso, Elia Valls Pascual

“…The complete and maintained resolution of the ocular inflammation will be assessed by masked evaluators (primary outcome). …”
Get full text