Characterization of Mucosal Immune-Related lncRNAs and mRNAs in a Mouse Model of Allergic Conjunctivitis by Zhang H, Zhang H, Leng Q, Zheng YJ

“…GO analysis indicated that both upregulated and downregulated genes were enriched in biological processes related to response to stimulus, immune system processes, signaling, and metabolic processes. …”
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Real-world clinical insights and aqueous humor biomarker analysis of diabetic macular edema subtypes classified by OCT following intravitreal injections by Liangzhang Tan, Shoukuan Liu, Wenrui Linghu, Yifeng Ke, Yongtao Li, Emmanuel Eric Pazo, Xinjun Ren

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Effectiveness of social support programmes on loneliness in community-dwelling older adults: study protocol for a meta-analysis of randomised controlled trials by Li Yao, Tingting Ren, Xiaofang Li, Yinhua Wang, Tingshu Wang

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Prevalence and temporal trends in myopia and high myopia children in China: a systematic review and meta-analysis with projections from 2020 to 2050Research in context by Wei Pan, Seang-Mei Saw, Tien Yin Wong, Ian Morgan, Zhikuan Yang, Weizhong Lan

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When do we need to perform a diagnostic lumbar puncture for neurometabolic diseases? Positive yield and retrospective analysis from a tertiary center by Göknur Haliloğlu, Emine Vezir, Leyla Baydar, Saniye Onol, Serap Sivri, Turgay Coşkun, Meral Topçu

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Non-specific effects of different sham acupuncture methods and their impact on true acupuncture effectiveness in migraine: a protocol for systematic review and network meta-analysi... by Fan Jiang, Haifeng Zhang, Lun Li, Qinhong Zhang, Meng Lin, Yongjian Liu, Yong Fu, Jiahui Yang, Qilin Liu, Meiyi Zhu, Xiumei Yan

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Is a thermal pulsation system (LipiFlow) effective as a standalone treatment for meibomian gland dysfunction and dry eye? A systematic review and meta-analysis by Kai-Yang Chen, Hoi-Chun Chan, Chi-Ming Chan

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The Influence of Glaucoma as a Comorbidity on Cytokine Expression in Aqueous Humor of Patients with Fuchs Endothelial Corneal Dystrophy and Bullous Keratopathy by N. V. Fisenko, T. A. Demura, G. A. Osipyan, K. S. Avetisov

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A first-in-human, prospective pilot trial of umbilical cord-derived mesenchymal stem cell eye drops therapy for patients with refractory non-Sjögren's and Sjögren's syndrome dry ey... by Di Zhang, Taige Chen, Qi Liang, Xuebing Feng, Jiaxuan Jiang, Zeying Chen, Yun Tang, Yiran Chu, Bin Wang, Kai Hu

“…Abstract Background Patients with refractory dry eye disease (DED) often face the threat of diminished visual quality and have limited responses to existing treatments. Ocular injection of Mesenchymal stem cells (MSCs) has recently emerged as a promising new therapeutic strategy for DED. …”
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Myopic choroidal neovascularization with dilated choroid vessels is prone to progression into subretinal fibrosis following anti-vascular endothelial growth factor therapy: a retro... by Xiangjun She, Qiwei Cai, Wangjing Yao, Shixin Zhao, Zhe Lv, Suyan Shan, Jiwei Tao, Yun Zhang

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The influence of corneal biomechanical factors on surgically induced corneal astigmatism by Yufan Yin, Yaning Li, Guihua Liu, Jiarui Su, Jiahui Lu, Yuanfeng Jiang, Xiteng Chen, Fang Tian, Bei Du, Shaochong Bu

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Identifying prioritization of therapeutic targets for ankylosing spondylitis: a multi-omics Mendelian randomization study by Lingyu Dai, Lan Xia, Guannan Su, Yu Gao, Qingyan Jiang, Peizeng Yang

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Orthokeratology for myopia control: a three-year longitudinal study on axial length modulation influenced by baseline age and spherical equivalent by Xiaoxue Hu, Zixun Wang, Boxuan Sun, Xiang Wan, Feng Chang, Weiping Lin, Ruihua Wei

“…Abstract Background Myopia, particularly high myopia (spherical equivalent (SE) ≤ -6.00D), poses significant risks of irreversible vision loss due to ocular complications. Orthokeratology (Ortho-k), a corneal reshaping intervention, has demonstrated efficacy in slowing axial length (AL) elongation. …”
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Revealing the structural microenvironment of high metastatic risk uveal melanomas following decellularisation by Karen Aughton, Joshua Hattersley, Sarah E Coupland, Helen Kalirai

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Chlamydia trachomatis ompA variants in trachoma: what do they tell us? by Aura A Andreasen, Matthew J Burton, Martin J Holland, Spencer Polley, Nkoyo Faal, David C W Mabey, Robin L Bailey

“…<h4>Background</h4>Trachoma, caused by Chlamydia trachomatis (Ct), is the leading infectious cause of blindness. Sequence-based analysis of the multiple strains typically present in endemic communities may be informative for epidemiology, transmission, response to treatment, and understanding the host response.…”
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Pathway-Wide Genetic Risks in Chlamydial Infections Overlap between Tissue Tropisms: A Genome-Wide Association Scan by Chrissy H. Roberts, Sander Ouburg, Mark D. Preston, Henry J. C. de Vries, Martin J. Holland, Servaas A. Morré

“…Genetic polymorphisms in molecular pathways involving G protein-coupled receptor signalling, the Akt/PI3K cascade, the mitotic cell cycle, and immune response have been identified in association with the development of trachomatous scarring, an ocular form of chlamydia-related fibrotic pathology. …”
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Changes in retinal and choroidal thickness after carotid endarterectomy: a systematic review by Ana Cibrão-Pedroso, João Rocha-Neves, Rafael Vieira, João Barbosa Breda, André Ferreira

“…Overall, variability in study designs, Optical Coherence Tomography protocols, and follow-up durations limits comparability, precluding meta-analysis. Conclusions This review highlights a potential association between carotid endarterectomy and improved ocular perfusion, as reflected by changes in choroidal thickness. …”
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Atypical migratory reactive arthritis related to Hepatitis C Virus by Clara C. Sánchez-Rodríguez, Ana M. Mendoza-Martínez, Héctor R. Sánchez-Nuncio, Jorge H. Luna-Domínguez

“…He begins with conjunctival injection, ocular pruritus, increased conjunctival secretion with ocular foreign body sensation, dysuria, and foamy urine. …”
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Deciphering mitochondrial dysfunction in keratoconus: Insights into ACSL4 from machine learning-based bulk and single-cell transcriptome analyses and experimental validation by Yuchen Cai, Tianyi Zhou, Xueyao Cai, Wenjun Shi, Hao Sun, Yao Fu

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Identification of a novel single nucleotide deletion in the NHS causing Nance-Horan syndrome by Teng Huang, Ya-Nan Liu, Dan-Tong Ding, Qiao Wang, Qiu-Ling Xie, Xue-Chuan Miao, Chuan Qin, Xiu-Feng Huang, Jin Li

“…This study aimed to identify the genetic cause responsible for NHS in a Chinese family with four individuals primarily presenting with congenital cataracts. …”
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